Clinical trials: Physical Fatigue
Neuromuscular Diseases
Effectiveness and Cost-effectiveness of the Energetic Program
Fatigue is present in at least 60% of the patients with a muscle disease and can be the most disabling symptom. In combination with other impairments, this often results in low levels of physical activity and decreased social…
- Trial name
- NCT02208687
- Testing
- Energetic, Control group
- Where
- Netherlands
- Volunteers
- 53 people
- Sponsor
- Radboud University Medical Center
Migraine
"Personalized Physiotherapy for Migraine: Effects on Pain, Fatigue, and Physical Function"
Migraine is a prevalent neurological disorder associated with pain, fatigue, and reduced physical function. The aim of this randomized controlled trial is to examine the effects of a personalized and structured physiotherapy…
- Trial name
- TIP-MIG (NCT07261384)
- Testing
- Personalized Structured Physiotherapy Intervention, Standard Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Physical Endurance, Muscle Fatigue
Assessment of the Acute Effect of Cycling Practice in Lumbar and Thigh Muscles
Introduction: Cycling represents a very important level of practice, being among the most practiced sports in Spain. As in any other sport discipline, its practice is associated with the appearance of overloads and sports…
- Conditions
- Physical Endurance, Muscle Fatigue, Musculoskeletal Pain, Muscle Tightness
- Trial name
- NCT03442933
- Testing
- 3 hours Road Cycling Time Trial, 3 hours Mountain Biking Time Trial
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Diabete Mellitus, Aging
Non-exercise Physical Activity Intervention
Physical inactivity is prevalent in older adults and poses a risk factor for the development of type 2 diabetes. The aim of this pilot study was to examine the effect of non-exercise physical activity using a standing desk on…
- Conditions
- Diabete Mellitus, Aging, Cognitive Change
- Trial name
- STAND (NCT04410055)
- Testing
- Sitting, Static standing, Dynamic standing
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Science and Research Centre Koper
Myasthenia Gravis
Can Interval Walking Influence on Fatigue in the Danish Cohort of Myasthenia Gravis Patients
The study is a controlled, randomized intervention trial. Patients are randomized into either an intervention group or a control group. The duration of the study is 10 weeks.
- Trial name
- NCT03900585
- Testing
- Interval walking
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Multiple Sclerosis
Feasibility of Web-based CBT-I Intervention in Individuals With Multiple Sclerosis
Forty individuals with multiple sclerosis (MS) will be randomly assigned to a 6-week web-based cognitive behavior therapy for insomnia intervention (wCBT-I) or to wCBT-I plus biweekly support meetings with research personnel via…
- Trial name
- NCT03783585
- Testing
- Cognitive behavioral therapy for insomnia, Cognitive behavioral therapy for insomnia + biweekly support
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Kansas Medical Center
Cancer-related Problem/Condition, Exercise
Combined Technology Enhanced Home Exercise Program and Other Non-pharmacological Intervention for Cancer Survivors
A 12 weeks technology enhanced home exercise (TEHE) program using mobile technologies that provide immediate feedback and send reminder messages to improve exercise motivation is developed.
- Conditions
- Cancer-related Problem/Condition, Exercise, Acupressure
- Trial name
- TEHEplus (NCT03576274)
- Testing
- Technology Enhanced Home Exercise (TEHE), Auricular Point Acupressure (APA), Mindfulness body scan (MBI)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
All Tumor Entities Treated With TKI Therapy
Reduction of Cancer Related Fatigue in Patients During TKI Therapy
The purpose of this pilot study is to determine the effects of a 12-week resistance training program on cancer related fatigue in cancer patients receiving tyrosine kinase inhibitor (TKI) therapy.
- Trial name
- RECAP (NCT01645150)
- Testing
- Progressive strength training
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- German Cancer Research Center
Idiopathic Pulmonary Fibrosis
Respiratory Muscle Strength in Patients With Idiopathic Pulmonary Fibrosis
Respiratory muscle strength, dyspnea perception, physical activity and quality of life measurements will be performed and groups will be compared in two groups consisting of patients with idiopathic pulmonary fibrosis referred to…
- Trial name
- NCT03588260
- Testing
- no intervention - cross-sectional observational only
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphoid System Neoplasm
Physical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Locally Advanced, Metastatic, or Recurrent Cancer
This phase II/III trial studies how well physical activity with or without dexamethasone works in reducing cancer-related fatigue in patients with cancer that has spread to other places in the body or has come back.
- Conditions
- Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphoid System Neoplasm, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT03583255
- Testing
- Dexamethasone, Exercise Intervention
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- M.D. Anderson Cancer Center
Colonic Cancer, Postoperative Care
Rehabilitation Following Laparoscopic Colonic Surgery
The standard procedure for treating colonic cancer is changing from open surgery to laparoscopic surgery. Following open colonic surgery patients are fatigued and loss body mass and have a reduction in physical function, but the…
- Conditions
- Colonic Cancer, Postoperative Care, Fatigue
- Trial name
- NCT00938210
- Testing
- Laparoscopic colonic surgery
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Aarhus University Hospital
Sleep Disturbance, Fatigue
Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease
The purpose of this study is to determine if either a targeted type of talk therapy (Phase I) or medication, Wellbutrin, (Phase II) improve sleep disturbance and/or fatigue in individuals with Inflammatory Bowel Disease (IBD).
- Conditions
- Sleep Disturbance, Fatigue, Inflammatory Bowel Disease
- Trial name
- NCT02162862
- Testing
- Behavioral Counseling, bupropion-SR
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Eva Szigethy
Hypertension, Elevated Blood Pressure
Blood Pressure Following Isometric Exercise in Inactive Adults
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed…
- Conditions
- Hypertension, Elevated Blood Pressure, Sedentary Lifestlye
- Trial name
- BELIEF-BP (NCT06937164)
- Testing
- Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Fatigue, Older Adults (65 Years and Older)
The Effect of a Passive Hip Exoskeleton on Daily-life Fatigue in Older Adults
This crossover study investigates whether a passive lower-limb exoskeleton (Exoband) can reduce perceived exertion during everyday mobility tasks in older adults.
- Trial name
- NCT07359573
- Testing
- Performance test, Exoband
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Multiple Sclerosis (MS)
Physical Capacity and Rehabilitation of Patients With Multiple Sclerosis
The purpose of this study is to assess the physical capacity of patients with multiple sclerosis and the effects of rehabilitation, encompassing physical therapy and physical activity as it is carried out in the day hospital of…
- Trial name
- REHABSEP (NCT02352194)
- Testing
- Rehabilitation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Multiple Sclerosis, Quality of Life
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
Patients with multiple sclerosis (MS) struggle on a daily basis with accompanying, "Invisible" symptoms like primary fatigue, pain and emotional-cognitive disorders.
- Conditions
- Multiple Sclerosis, Quality of Life, Motivation, Pain
- Trial name
- NCT03768830
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Chronic Physical Health Conditions
MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace
The specific aim of the study is to evaluate the health benefits of a series of group workshops designed for workers with chronic physical health conditions.
- Trial name
- NCT01978392
- Testing
- Self-management group workshops
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Metabolic Syndrome
Determination Physical Activity Levels,Quality Life,Depression and Fatigue Severity Individuals With Metabolic Syndrome
The aim of the study was to determine the Physical Activity Levels, Quality of Life, Depression and Fatigue Severity of Individuals with Metabolic Syndrome.
- Trial name
- NCT05184634
- Testing
- PHYSICAL ACTIVITY LEVELS, DEPRESSION LEVELS, FATİGUE SEVERİTY
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Büşra Sarıkaya
Fall, Fatigue
Determinants of the Fall Risk Profile and Quality of Life of Older Subjects Visting Climatic Health Resorts
The main objective of the study conducted in subjects aged 65 or older visiting the French Balaruc-les-bains climatic health resort was to : Determine factors that distinguish fallers from not fallers Determine factors that may…
- Trial name
- NCT04277000
- Where
- France
- Volunteers
- 1,471 people
- Sponsor
- University Hospital, Montpellier