Clinical trials: Physical Function, open to volunteers
Postoperative Pain, Shoulder Arthroscopic Surgeries
Interscalene Block Versus Infraspinatus-Teres Minor Interfascial Plane Block for Shoulder Arthroscopy
This prospective randomized controlled study aims to compare the effects of interscalene block, infraspinatus-teres minor interfascial plane block, and a control group on postoperative analgesia and diaphragmatic function in…
- Conditions
- Postoperative Pain, Shoulder Arthroscopic Surgeries, Diaphragmatic Dysfunction
- Trial name
- NCT07670780
- Testing
- Ultrasound-Guided Interscalene Block, Ultrasound-Guided Infraspinatus-Teres Minor Interfascial Plane Block
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
Autism Spectrum Disorder, Gastrointestinal Diseases
Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.
This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Diseases, Healthy
- Trial name
- NCT06290258
- Testing
- Fecal microbiota transplantation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy, Stroke
Influence of Brain Oscillation-Dependent TMS on Motor Function
Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands.
- Conditions
- Healthy, Stroke, Normal Physiology, Aging
- Trial name
- NCT03288220
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sleep, Cardiovascular Risk Factor
Sleep Duration and Cardiovascular Health
This is a cross-sectional study with an optional intervention that will examine how extreme sleep durations relate to cardiovascular health, physical activity, and sleep quality by studying three groups of participants: short…
- Trial name
- Goldilocks (NCT04804124)
- Testing
- Regularized Sleep Schedule
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Spinal Cord Injuries (SCI)
Spatiotemporal tSCS in Spinal Cord Injury
Spinal cord injury leads to long-lasting impairment, and currently, there is no cure for paralysis. Although transcutaneous spinal cord stimulation has shown promising results in recovering lost movements, its poor selectivity in…
- Trial name
- NCT07397559
- Testing
- No Stimulation, Conventional tSCS, Spatiotemporal tSCS
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Washington University School of Medicine
Parkinson Disease
The Effects of Ischemic Conditioning in Individuals With Parkinson's Disease
Ischemic conditioning (IC) is a promising therapy that can mimic the physiological effects of physical exercise. IC consists of using a cuff to measure blood pressure and calibrate 200 mmHg on the upper or lower limb.
- Trial name
- NCT06293118
- Testing
- Ischemic conditioning group
- Volunteers
- 50 people
- Sponsor
- Hospital Israelita Albert Einstein
Duchenne Muscular Dystrophy (DMD)
The Effect of Dual-tasking Program on Cognitive and Physical Functions and Independence in Activities of Daily Living in Children With Duchenne Muscular Dystrophy: A Single-blind Randomized Controlled Trial
Duchenne Muscular Dystrophy (DMD) is an X-linked recessive disorder characterized by progressive muscle degeneration and frequent developmental, cognitive and behavioral impairments, occurring in one in 5000 live births of boys.
- Trial name
- DMD-DUAL-FUNC (NCT06887491)
- Testing
- Conventional physiotherapy program, Conventional physiotherapy program + Dual task program
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Lokman Hekim University
Diabetes Mellitus
Convenient Home Access for Routine Monitoring in Diabetes (Charm-D Study)
Diabetes mellitus is a global problem and regular monitoring of blood sugar control is important to reduce the risk of complications secondary to poor sugar control.
- Trial name
- CHARM-D (NCT06695325)
- Testing
- HbA1c test
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Tameside General Hospital
Alzheimer's Disease (AD)
Amyloid-β Clearance Mechanisms in Alzheimer's Disease
The focus of this study is to examine the protein-plaque clearance (Aß) in relation to the blood-brain-barrier, the glymphatic system, brain lymphatic system and enzymatic degradation.
- Trial name
- AmyClearAD (NCT05059158)
- Testing
- positron emission tomography (PET)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Laryngeal Dystonia, Focal Dystonia
Effects of Neuromodulation in Laryngeal Dystonia
Laryngeal dystonia (LD) causes excessive vocal fold abduction (opening) or adduction (closing) leading to decreased voice quality, job prospects, self-worth and quality of life.
- Trial name
- NCT05095740
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Tensiomyography, Gastrocnemius Muscle Assessment
Tensiomyography of Gastrocnemius in Lumbar Radiculopathy
This cross-sectional study aims to evaluate the neuromuscular characteristics of the gastrocnemius muscles in individuals with chronic lumbar radiculopathy using tensiomyography (TMG).
- Conditions
- Tensiomyography, Gastrocnemius Muscle Assessment, Chronic Lumbar Radiculopathy
- Trial name
- TMGGLR (NCT06767280)
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Postpartum Sexual Dysfunction, Postpartum Depression
POSH-Ex: Physiotherapist-Led Telerehabilitation Exercise Programme for Postpartum Sexual Health
Postpartum women frequently experience impairments in sexual function, pelvic floor dysfunction, fatigue, and depressive symptoms, all of which may adversely affect their quality of life during the postpartum period.
- Conditions
- Postpartum Sexual Dysfunction, Postpartum Depression, Fatigue, Physical Activity
- Trial name
- POSH-Ex (NCT07747285)
- Testing
- POSH-Ex (Postpartum Sexual Health Exercise)
- Where
- Croatia
- Volunteers
- 84 people
- Sponsor
- University Medical Centre Ljubljana
Sarcopenia, Gestational Diabetes Mellitus (GDM)
Sarcopenia in Gestational Diabetes
Sarcopenia is a syndrome characterized by loss of skeletal muscle mass and strength, and physical performance deterioration. Prevalence of sarcopenia in elderly people is remarkably high (prevalence of about 25% in 60+ years…
- Conditions
- Sarcopenia, Gestational Diabetes Mellitus (GDM), Pregnancy Complications, Adverse Maternal and Neonatal Outcomes
- Trial name
- SiGnal-D (NCT06876090)
- Testing
- Sarcopenia tests (for muscle mass, muscle function, physical performance), Oral Glucose Tolerance Test, Montreal Cognitive Assessment
- Where
- 3 sites in Austria, Italy
- Volunteers
- 200 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
Knee Pain
Validity and Reliability of Video-Based Functional Physiotherapy Assessment of Subacute Knee Injuries
This study aims to validate a function-based physiotherapy assessment for subacute knee pain without using specific knee tests. Assessments are conducted either in-person or via video consultations in primary care.
- Trial name
- NCT07212920
- Testing
- Physiotherapy digital assessment, Physiotherapy assessment - only functional tests
- Where
- 3 sites in Sweden
- Volunteers
- 138 people
- Sponsor
- Vastra Gotaland Region
Kidney Transplant Rejection
AIIM Trial: Personalized Medicine Approach to Kidney Allograft Function
The objective of the proposed study it to perform a pilot clinical trial both to establish feasibility of applying a computational, augmented intelligence based approach, Phenotypic Precision Medicine (PPM), to optimizing…
- Trial name
- AIIM (NCT05432765)
- Testing
- Phenotypic Personalized Medicine Dosing, Standard of Care Dosing
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Florida
Healthy Volonteers
Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function
Local vibration is a non-invasive neuromuscular stimulation modality used in training and rehabilitation for its effects on neuromuscular function, particularly its ability to induce nervous adaptations.
- Trial name
- VIB-EXPRESS (NCT07344298)
- Testing
- Local vibration protocol
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Non-small Cell Lung Cancer, Lung Cancer
3D Virtual Resection for Predicting Lung Function in VATS
This study aims to validate a novel preoperative assessment strategy using three-dimensional (3-D) computed tomography (CT) reconstruction and virtual resection simulation.
- Conditions
- Non-small Cell Lung Cancer, Lung Cancer, Lung Neoplasms
- Trial name
- NCT07436598
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Stroke
Cranial Nerve Neuromodulation to Improve Arm Function and Brain Plasticity in Stroke
Following a stroke, persistent residual muscle weakness in the upper limb (UL) drastically impacts the individuals' quality of life and level of independence.
- Trial name
- CN-NINM (NCT06386510)
- Testing
- Strength training, Cranial nerve non-invasive neuromodulation
- Where
- 3 sites in Canada
- Volunteers
- 74 people
- Sponsor
- Université de Sherbrooke
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Blood Flow Restriction Training, Patella Position
BFR Training for Post ACLR
This randomized clinical trial is designed to compare three different rehabilitation methods for patients who have undergone anterior cruciate ligament (ACL) reconstruction.
- Conditions
- Blood Flow Restriction Training, Patella Position, Muscle Morphology, Anterior Cruciate Ligament Reconstruction
- Trial name
- NCT07142889
- Testing
- Low load-BFRt, High load-Eccentric training
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Udayana University
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