Clinical trials: Physical Function, open to volunteers
Dysphagia, Esophageal
Striated Esophageal Motor Function Modulation in Health and Disease
The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.
- Trial name
- NCT05708885
- Testing
- Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction, Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
- Where
- United States
- Volunteers
- 557 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Pain, Postoperative, Muscle Weakness
Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty
The goal of this clinical trial is to compare two regimens of the pericapsular nerve group (PENG) block, an ultrasound-guided injection of local anaesthetic targeting the nerves supplying the front of the hip joint, for…
- Conditions
- Pain, Postoperative, Muscle Weakness, Arthroplasty, Replacement, Hip
- Trial name
- NCT07855341
- Testing
- Pericapsular nerve group (PENG) block, Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Chronic Low Back Pain
Virtual Reality-Based Rehabilitation Versus Conventional Therapy in Patients With Chronic Low Back Pain
This study aims to evaluate the effectiveness of rehabilitation using virtual reality compared with conventional physiotherapy in patients with chronic low back pain.
- Trial name
- NCT07463105
- Testing
- Virtual Reality-Assisted Rehabilitation, Conventional Rehabilitation
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- University of Rzeszow
Cognition, Mood
Investigation on the Chronic Effects of Nepalese Pepper (Zanthoxylum Armatum DC) on Cognitive Function, Mood and Gaming Performance in Young, Healthy, Action Video Gamers
The goal of this clinical trial is to learn if daily supplementation with a Nepalese Pepper Extract (Zanthoxylum Armatum, ZA) can improve cognitive performance and gaming performance in action video gamers aged 16 to 39, when…
- Conditions
- Cognition, Mood, Gaming Performance, Fatigue
- Trial name
- NCT07752329
- Testing
- Nepalese Pepper (Zanthoxylum Armatum DC) extract 275mg
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Non-functioning Pituitary Adenoma
Individualized Physical Activity or Patients With Non Functioning Pituitary Adenoma
The goal of this clinical trial is to learn about physical activity's effect on health in people who have had surgery of a non-functioning pituitary adenoma.
- Trial name
- NCT06163261
- Testing
- Physical activity
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Vastra Gotaland Region
Swimming, Inspiratory Muscle Strength
Effects of Inspiratory Training on Respiratory Function in Swimming
Introduction: The diaphragm is the primary inspiratory muscle and plays a key role in ventilation, trunk stability, and exercise efficiency.
- Conditions
- Swimming, Inspiratory Muscle Strength, Inspiratory Muscle Training
- Trial name
- NCT07595341
- Testing
- Inspiratory training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Sacubitril/Valsartan, Hypertension
Effect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World Study
The purpose of this study is to investigate the effect of sacubitril/valsartan on cardiac function assessed by cardiac magnetic resonance (CMR) in hypertensive patients stratified by BMI.
- Conditions
- Sacubitril/Valsartan, Hypertension, Obesity
- Trial name
- NCT05498675
- Testing
- Sacubitril / Valsartan Oral Tablet [Entresto], ACEI/ARB
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Friendship Hospital
ACS - Acute Coronary Syndrome, Ticagrelor
Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor
The FLORA-ACS study aims to evaluate the relationship between dysbiosis and high platelet reactivity during treatment with ticagrelor in patients with a history of acute coronary syndromes and investigate the use of rifaximin to…
- Conditions
- ACS - Acute Coronary Syndrome, Ticagrelor, Microbiota, Platelet Aggregation
- Trial name
- FLORA-ACS (NCT07203846)
- Testing
- Rifaximin
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Respiratory Muscles, Cardiorespiratory Fitness
Effects of Aerobic and Diaphragmatic Exercises on Choir Singers
The goal of this randomized-controlled study is to compare the effects of diaphragmatic breathing exercise training provided by a physiotherapist and aerobic exercise training applied in addition to diaphragmatic breathing…
- Trial name
- NCT06745869
- Testing
- Diaphragmatic breathing exercise training, Aerobic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medipol University
Liver Transplant, Erector Spina Plan Block
Perioperative Analgesia With Erector Spinae Plane Block in Liver Transplant Recipients
The goal of this clinical trial is to learn if ESP block is safe and effective for perioperative analgesia in patients undergoing liver transplant.
- Trial name
- NCT06857331
- Testing
- Erector Spinae Plane Block using 0.2% ropivacaine
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Bogomolets National Medical University
Aged, Exercise Therapy
Comparative Effects of Multicomponent Training Concerning Elastic Band Training on Physical Fitness, Postural Balance, and Health-related Quality of Life in Older Women
Objective: To compare the effects of MCT versus EBT on functional fitness, postural balance, and HRQoL in older women. Methods: Single-blind, parallel-group randomized controlled trial lasting 16 weeks (2 sessions/week, 60 min).
- Conditions
- Aged, Exercise Therapy, Physical Performance
- Trial name
- RCT (NCT07561879)
- Testing
- Multicomponent training program, Elastic band training program
- Volunteers
- 40 people
- Sponsor
- Universidad Católica del Maule
Infertility, Female, Perimenopausal Disorder
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
- Conditions
- Infertility, Female, Perimenopausal Disorder, Menstrual Cycle Abnormal
- Trial name
- PRP (NCT03951194)
- Testing
- Autologous Platelet Rich Plasma (PRP) intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Spina Bifida
Motor Imagery-Supported Thoracic Expansion in Children With Spina Bifida
This study will investigate whether adding motor imagery to thoracic expansion exercises can improve respiratory function in children with spina bifida.
- Trial name
- NCT07846202
- Testing
- Thoracic Expansion Exercises, Motor Imagery-Supported Thoracic Expansion Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Kyphosis
Comparison of Exercise With & Without Bracing in Office Workers With Kyphosis
The study aims to Compare PT and bracing in improving posture, pain, and functionality in patient with kyphosis. It also assess the additive benefits of combining PT with bracing.
- Trial name
- NCT06867003
- Testing
- physical therapy with bracing, physical therapy without bracing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Arterial Hypertension, Resistant Hypertension
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity.
- Conditions
- Arterial Hypertension, Resistant Hypertension, Microvascular Function, Nitrate Supplementation
- Trial name
- NCT06169241
- Testing
- Beetroot extract
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Normal Physiology, Alcohol Use Disorder
Addictions Neuroclinical Assessment (ANA)
Background: Alcohol use disorder (AUD) is a major public health problem. In the U.S., 16 to 18 million adults have an AUD. Researchers want to test an assessment tool called the ANA.
- Trial name
- NCT04946851
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Primary Progressive Aphasia
Enhancing Language Function in Primary Progressive Aphasia
This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA).
- Trial name
- PPA (NCT04920318)
- Testing
- tDCS + language therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arizona
Structure and Function of MRI
Ultrahigh Field Body MR Imaging
The primary objective of this study is to develop new ways to acquire MRI data and/or new ways to analyze the acquired data.
- Trial name
- NCT02236143
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Multiple Sclerosis, Healthy Controls Group - Age and Sex-matched
Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis
Walking and motor control impairments are among the most common manifestations experienced by people with multiple sclerosis (pwMS) and may already be present in individuals with mild disability.
- Trial name
- NCT07505355
- Where
- 4 sites in Belgium, Italy and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Stroke, Post Stroke Hand Rehabilitation
Effects of Neuromuscular Electrical Stimulation With Neural Mobilization in Stroke Patients
The goal of this clinical trial is to learn if neuromuscular electrical stimulation combined with upper limb neural mobilization works to improve hand grip and upper limb function in post-stroke patients.
- Trial name
- NCT07629908
- Testing
- Conventional physical therapy, Neuromuscular Electrical Stimulation
- Volunteers
- 44 people
- Sponsor
- Riphah International University
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