Clinical trials: Physical Function Improvement
Tricuspid Insufficiency, Tricuspid Regurgitation (TR)
PASCAL Precision-GDMT Registry
The goal of this observational study is to demonstrate that successful tricuspid valve repair with the PASCAL Precision System in participants with at least severe tricuspid insufficiency and left ventricular dysfunction will be…
- Conditions
- Tricuspid Insufficiency, Tricuspid Regurgitation (TR), Left Ventricular Cardiac Dysfunction, Left Ventricular (LV) Systolic Dysfunction
- Trial name
- PASCAL (NCT07578129)
- Volunteers
- 50 people
- Sponsor
- Ceric Sàrl
Impotence
Improvement of Erectile Dysfunction by Fluvastatin in Patients With Cardiovascular Risk Factors
The purpose of the study is to determine the effect of fluvastatin on penile arterial blood flow and erectile function in patients with arteriogenic ED and cardiovascular risk factors.
- Trial name
- NCT00382161
- Testing
- Fluvastatin-sodium
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital, Saarland
Attention Deficit Hyperactivity Disorder
Concerta and Strattera on the Executive Function in Attention Deficit Hyperactivity Disorder (ADHD) Children
The objective of this study is to compare the effect of Concerta (Osmotic Release Oral System Extended Release Methylphenidate HCL, OROS MPH) and Strattera (Atomoxetine) on the laboratory and ecological executive function in…
- Trial name
- NCT01065259
- Testing
- OROS MPH, Atomoxetine
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Peking University
Cognitive Decline
A Home-based e-Health Intervention in the Elderly: MOVI-ageing
This protocol study aims to evaluate the efficacy of the MOVI-ageing intervention, a complex home-based eHealth intervention of cognitive-demanding exercise for the elderly, in improving: global cognitive function and basic…
- Trial name
- MOVI-ageing (NCT05928078)
- Testing
- intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Cognitive Function 1, Social
Effects of Wheat Bran Extract on Cognitive and Memory Function
The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of water extract from wheat Triticum aestivum L on cognitive and memory function.
- Trial name
- NCT02489747
- Testing
- WBE
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Obstructive Sleep Apnea Syndrome, Obesity
Influence of nCPAP on Metabolic Consequences Associated With OSAS
Context: Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular morbidity. Recurrent episodes of occlusion of upper airways during sleep result in hormonal changes that may predispose to high cardiovascular…
- Trial name
- NCT00435643
- Testing
- nasal continuous positive airway pressure
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Alzheimer's Disease
Efficacy, Safety and Response Predictors of Astragalus Membranaceus on the Improvement of Cognitive Function in Mild-to-Moderate Alzheimer's Disease
Alzheimer's disease (AD), the most common cause of dementia, is characterized by cognitive impairment, mental and behavioural abnormalities, and social dysfunction.
- Trial name
- NCT05578443
- Testing
- 10g Astragalus, Routine treatment, 20g Astragalus
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fujian Medical University Union Hospital
Frailty, Cognitive Decline
The Effectiveness of a Dual-task Training Program
The purpose of this study is to explore the effect of a dual-task training intervention on cognitive function,physical function, depression symptoms and quality of life in middle-aged and elderly people with cognitive impairment.
- Trial name
- NCT06450119
- Testing
- walking training, cognition training
- Volunteers
- 196 people
- Sponsor
- Taipei Medical University
ST-segment Elevation Myocardial Infarction (STEMI)
The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction
The aim of the study was to intervene in the Aerobic exercise time of patients with STEMI and to explore the optimal exercise time for STEMI patients
- Trial name
- NCT06385834
- Testing
- Morning aerobic exercise, Evening aerobic exercise
- Where
- China
- Volunteers
- 201 people
- Sponsor
- RenJi Hospital
Alzheimer's Disease
Endothelial Facilitation in Alzheimer's Disease
Purpose of the study: Patients with mild Alzheimer's Disease will be given three different drugs over a 4-month period to try to increase the blood flow to their brains, and improve blood vessel and brain function.
- Trial name
- NCT01439555
- Testing
- Simvastatin, L-Arginine, Tetrahydrobiopterin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Massachusetts, Worcester
Osteoarthritis (OA) of the Knee
Effectiveness of Stanley Paris Manual Therapy vs. Conventional Physiotherapy in Reducing Pain and Improving Function in Grade II Knee Osteoarthritis
This study aims to compare two different physiotherapy approaches for people suffering from Grade II Knee Osteoarthritis (OA) - a condition that causes knee pain, stiffness, and difficulty in walking.
- Trial name
- SPMT vs CPT in (NCT07317375)
- Testing
- Hands-on manual therapy including joint mobilization, soft tissue and neural mobilization, and movement retraining based on the Stanley Paris Concept., Conventional Physiotherapy Standard physiotherapy care including electrotherapy modalities (TENS, ultrasound), strengthening, flexibility, and balance training exercises.
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Ibadat International University, Islamabad
Knee Osteoarthritis
Improvement in Pain and Function Following a Physiotherapy Program in Older Adults With Knee Osteoarthritis
This study evaluates the combination of a therapeutic exercise program and dry needling in the treatment of knee osteoarthritis in older adults.
- Trial name
- NCT02698072
- Testing
- Therapeutic exercise, Dry needling
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Exercise Therapy, Chronical Kidney Disease
Therapeutic Exercise Programme to Improve the Functional Capacities, Depression and Anxiety of Patients With Chronic Kidney Disease During Haemodialysis Sessions.
Therapeutic Exercise During Outpatient Hemodialysis Treatment for Patients with Chronic Kidney Disease
- Trial name
- Actyren-HD (NCT06883968)
- Testing
- Therapeutic exercise during hemodialysis session
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- University of Vic - Central University of Catalonia
Intestinal and Immune Function Improved
The Effect of Probiotics on the Improvement of Intestinal and Immune Function
Evaluate the effectiveness and safety of Lactobacillus delbrueckii subsp. bulgaricus LB42 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
- Trial name
- NCT06873438
- Testing
- Probiotic group
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Chronic Obstructive Pulmonary Disease
Observational Non-interventional Study With Spiriva in Chronic Obstructive Pulmonary Disease Patients With Exercise-induced Dyspnoea
This observational non-interventional study is designed to demonstrate the improvement of physical function in COPD patients with exercise-induced dyspnoea on treatment with Spiriva (tiotropium 18 µg capsules) and allows adverse…
- Trial name
- NCT00540163
- Where
- 177 sites in Germany
- Volunteers
- 1,296 people
- Sponsor
- Boehringer Ingelheim
Fibromyalgia
Development of Treatments Aiming at Improvement of Function in Patients With Chronic Widespread Pain
The study aims to evaluate the effects of adding supervised exercise in supplement to an educational self-management program, and to determine which subgroups would gain effects of the treatment.
- Trial name
- NCT00545649
- Testing
- Exercise and education, Education
- Where
- 3 sites in Sweden
- Volunteers
- 164 people
- Sponsor
- Göteborg University
Cervical Cancer, Postoperative Bladder Dysfunction
Transcutaneous Electrical Nerve Stimulation in Nerve-Sparing Radical Hysterectomy: Effects on Bladder Management and Quality of Life in Cervical Cancer
To evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on bladder management, pelvic floor muscle strength, and quality of life (QoL) in patients undergoing nerve-sparing radical hysterectomy (NSRH) for…
- Conditions
- Cervical Cancer, Postoperative Bladder Dysfunction, Urinary Retention, Pelvic Floor Muscle Weakness
- Trial name
- NCT07070687
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Fudan University
Exercise, Parkinson Disease
Comparing the Effects of Instability Resistance Training Versus Aerobic Training on Cognitive and Motor Improvements Found in Parkinson's Disease Participants
This study will be looking at the effects that instability resistance training and aerobic training, individually, have on the improvement of various motor and cognitive impairments present in individuals with Parkinson' disease.
- Trial name
- NCT03711955
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Alcoholic Liver Disease
Herbal Supplements for Improvement of Liver Function in Participants With Alcoholic Liver Disease
Alcoholic liver disease represents the major health issues and it ranges from simple steatosis to cirrhosis. There is a paucity of data to support the allopathic intervention among these group of patients.
- Trial name
- NCT03503708
- Testing
- Livitol-70
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Composite Interceptive Med Science
Acute Coronary Syndrome
Study on Prediction of Left Ventricular Remodeling Using ST2
Patients who underwent percutaneous coronary intervention after diagnosis of acute coronary syndrome should be enrolled in the study and follow - up.
- Trial name
- TRUSTED (NCT03841214)
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Keimyung University Dongsan Medical Center