Clinical trials: Physical Function Improvement
Elbow Fractures
The Efficacy of Telerehabilitation Program for Improvement of Upper Limb Function Among Adults Post Elbow Fractures
This experimental research aims to examine the efficacy of Telerehabilitation treatment using a computerized system (MediTouch) in improving the upper limb function post elbow fractures.
- Trial name
- NCT02713958
- Testing
- Telerehabilitation, Rehabilitation
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center
Stroke, TDCS
BSD-10CH TDCS for Upper Limb Function Improvement in Stroke Patients: a Randomized Clinical Trial
This clinical study compares the effectiveness and safety of the BSD-10CH transcranial direct current stimulation (tDCS) device, applied alongside rehabilitation therapy, with a control device in stroke patients.
- Trial name
- NCT06740604
- Testing
- BSD-10CH
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Pusan National University Yangsan Hospital
Myocardial Infarction, Death
BAMI. The Effect of Intracoronary Reinfusion of Bone Marrow-derived Mononuclear Cells(BM-MNC) on All Cause Mortality in Acute Myocardial Infarction
This is a multinational, multicentre, randomised open-label, controlled, parallel-group phase III study. Its aim is to demonstrate that a single intracoronary infusion of autologous bone marrow-derived mononuclear cells is safe…
- Trial name
- BAMI (NCT01569178)
- Testing
- Bone Marrow aspiration and intracoronary reinfusion
- Where
- 33 sites in Belgium, Czechia and 8 more
- Volunteers
- 375 people
- Sponsor
- Queen Mary University of London
Acute Respiratory Distress Syndrome (ARDS)
Application of Electrical Impedance Tomography in Evaluating Pulmonary Function Improvement After High Lateral Recumbent Position Therapy in ARDS Patients
This randomized controlled trial investigates the effects of prone positioning versus lateral positioning at different angles (30°, 90°, 120°) on pulmonary function improvement in patients with acute respiratory distress syndrome…
- Trial name
- NCT07375849
- Testing
- Place the patient in the 90-degree high lateral position., Place the patient in the 30-degree low lateral position., Place the patient in the 120-degree high lateral position.
- Volunteers
- 140 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Chronic Low Back Pain (Non-specific, Uncomplicated)
Telerehabilitation Program to Improve Function in People With Chronic Low Back Pain Compared With Conventional Care
The goal of this clinical trial is to evaluate whether an additional telerehabilitation program, combined with conventional care, can improve functional recovery in adults with chronic low back pain treated in primary care…
- Trial name
- TELEREHAB-LC (NCT07248813)
- Testing
- Telerehabilitation Program, Conventional care
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Mild Cognitive Impairment, Alzheimer's Disease(AD)
Neuclare Device for Temporary Improvement of Executive Function in Patients With Mild Cognitive Impairment and Prodromal Alzheimer's Disease
This study is a multicenter, randomized, double-blind, parallel-group, prospective confirmatory clinical trial designed to evaluate whether the Neuclare medical device can temporarily improve executive function (planning and…
- Trial name
- NCT07239310
- Testing
- Participants receive Neuclare Device while continuing their cognitive medication
- Where
- 7 sites in South Korea
- Volunteers
- 138 people
- Sponsor
- Deepsonbio
Acquired Brain Injury, Executive Function Disorder
Goal Management Training (GMT) for Improvement of Cognitive Control Function After Acquired Brain Injury
The goal of this clinical trial is to investigate predictors of treatment outcome, and the effect of individual treatment components of Goal Management Training (GMT) for improvement of cognitive control function in people with…
- Trial name
- NCT06604000
- Testing
- GMT Usual, GMT Cuing, GMT Boost
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- St. Olavs Hospital
Bronchial Asthma
Two Inhalation Methods Using a Pressurized Metered Dose Inhaler With Valved Holding Chamber to Assess Improvement in Lung Function After SABA Administration in Bronchial Asthma
Bronchial asthma is a chronic inflammatory disorder characterized by recurrent reversible episodes of breathlessness, wheezing, chest tightness and/ or cough.
- Trial name
- NCT05428956
- Testing
- Single Inhalation technique, Tidal inhalation technique
- Where
- 2 sites in India
- Volunteers
- 897 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Peripartum Cardiomyopathy
Effect of Bromocriptine on Left Ventricular Function in Women With Peripartum Cardiomyopathy
This is a randomized, controlled clinical trial to evaluate the efficacy and safety of bromocriptine for improvement of left ventricular function of women with Peripartum cardiomyopathy (PPCM). A Multi center trial in Germany.
- Trial name
- PPCM (NCT00998556)
- Testing
- Bromocriptine
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Hannover Medical School
Back Pain Lower Back
Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory)
Our clinical trial has the purpose to evaluate the effectiveness in reducing pain and improving function and quality of life during a 6-months follow-up of a therapeutic exercise program compared to pharmacological treatment with…
- Trial name
- DLSEA (NCT01374269)
- Testing
- Exercise program, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- 2 sites in Colombia
- Volunteers
- 90 people
- Sponsor
- Grupo Rehabilitacion en Salud
Reduction in Pain, Reduction of Inflammation
Hand OA AND Methotrexate Use
Osteoarthritis (OA) is a common disabling condition, for which no effective therapy currently exists. Synovitis has been demonstrated in hand OA imaging.
- Conditions
- Reduction in Pain, Reduction of Inflammation, Improvement in Function
- Trial name
- Hand OA & MTX (NCT01927484)
- Testing
- 25 mg/week oral methotrexate tablets
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- University of Alexandria
Heart Failure
Evaluation of Myocardial Improvement in Patients Supported by Ventricular Assist Device Under Optimal Pharmacological Therapy
Cardiac function may improve in patients with end-stage heart failure who receive long-term support with ventricular assist devices (VAD).
- Trial name
- NCT00402376
- Testing
- Pravastatin, Carvedilol, Perindopril, Biventricular assist device (Thoratec paracorporeal assist device)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Stroke
Robotic Rehabilitation of the Upper Limb After a Stroke
Hemiparesis is the most common motor disorder after a stroke. Most patients do not recover functional use of their paretic upper limb.
- Trial name
- ROBOASSIST (NCT03584477)
- Testing
- Robot InMotion 2.0, Conventional rehabilitation
- Where
- 2 sites in France
- Volunteers
- 54 people
- Sponsor
- Clinique Les Trois Soleils
Stroke
Effect of U-Health Service in Stroke Patients
Provides mobile programs for occupational and speech therapy to patients with stroke.
- Trial name
- NCT01815905
- Testing
- Mobile program for occupational and speech therapy, Traditional rehabilitation therapy
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Bundang Hospital
Hematologic Disease, Hemophilia A
BAY14-2222 Prophylaxis and Joint Function Improvement (Adults)
The purpose of the study is to evaluate the effect of prophylactic treatment on the number of joint bleeds and quality of life in severe hemophilia A subjects compared to on-demand treatment in a one-group two-treatment schedule…
- Trial name
- NCT00586521
- Testing
- Kogenate (BAY14-2222)
- Where
- 11 sites in United States, France and 3 more
- Volunteers
- 20 people
- Sponsor
- Bayer
Liver Disease, Liver Cirrhosis
Hepatocyte Matrix Implant Study
This clinical investigation of the hepatocyte matrix implant is an evaluation blinded non-randomized and monocentric pilot study of Phase I, which is conducted as a therapeutic investigation.
- Trial name
- HMI (NCT00935454)
- Testing
- Hepatocyte matrix implantation
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Baermed
Irritable Bowel Syndrome
Feasibility Assessment of Cardiovascular Endurance Training for the Symptomatic Improvement of Irritable Bowel Syndrome Patients With a Sedentary and Non-active Lifestyle.
This exploratory study's primary objective is the changes of irritable bowel syndrome (IBS) symptom severity by cardiovascular endurance training (CET) in relation to the baseline sedentary or non-active lifestyle.
- Trial name
- NCT05680766
- Testing
- Cardiovascular endurance training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Obesity, Heart Failure, Diastolic
Improving Metabolic Health in Patients With Diastolic Dysfunction
The purpose of this study is to determine whether 1 year of supervised exercise training in obese individuals at high risk for developing HF, incorporating high intensity interval training (HIIT) two to three times per week in…
- Conditions
- Obesity, Heart Failure, Diastolic, Metabolic Syndrome
- Trial name
- MTG (NCT03448185)
- Testing
- High intensity exercise, Omega-3 fish oil, Yoga
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Ischemic Cardiomyopathy
Eccentric Manual Resistance Training in Patients With Ischemic CMP
Patients with ischemic cardiomyopathy and mildly reduced ejection fraction suffer from reduced functional capacity and fatigue caused by loss of muscle strength and reduced aerobic capacity.
- Trial name
- NCT04829955
- Testing
- Eccentric manual resistance training, Concentric manual resistance resistance training
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Vienna Hospital Association
Erectile Dysfunction
LiST Plus PRP Injection Therapy vs LiST Monotherapy for ED Treatment
We designed a double blind randomized sham-controlled trial in order to investigate and compare the treatment efficacy of LiST plus PRP intracorporeal injection vs LiST plus placebo (normal saline intracorporeal injection) in men…
- Trial name
- NCT05366504
- Testing
- LiST + PRP intracorporeal injection
- Volunteers
- 60 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece