Clinical trials: Physical Function in Older Adults
Frail Elderly, Aging
Targeting Aging With a Ketone Ester for Function in Frailty
This study aims to find out if a food supplement that contains a naturally occurring substance, ketones, can help to improve strength and general wellness in adults at, or over the age of 65 years who are experiencing a slight…
- Conditions
- Frail Elderly, Aging, Immune Function, Muscle Function
- Trial name
- TAKEOFF (NCT06645847)
- Testing
- Ketone ester
- Where
- 3 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging
Stroke
Effect of Task Oriented Training on Cognitive Function in Elderly Stroke Patients
Background: The impact of stroke at the time of diagnosis is on the attention and executive functions, which may be impaired at various post-stroke intervals.
- Trial name
- NCT06445998
- Testing
- task oriented training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Mild Cognitive Impairment
Effects of Brain Training Games on Cognitive Function and Quality of Life in MCI
The study aims to determine the effects of brain training games on cognitive function and Quality of life among older adults with MCI.
- Trial name
- NCT06437704
- Testing
- Brain training game Lumosity, Simulation game simcity buildit
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Healthy People Programs
Boxing Training, Physical-functional Fitness and Cognitive Performance in Older Adults
The aim of the study is to evaluate and to compare the effects of two exercise regimes (Boxing Training -BT and Multicomponent Training -MT) and 12 weeks of follow-up on cognitive health status, physical-functional fitness, and…
- Trial name
- Boxe4Ageing (NCT05826314)
- Testing
- Boxing training, Exercise
- Where
- Portugal
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Chronic Pain
Reactions of Older Adults Driving After Cannabis Exposure
Objective of the Protocol: The primary aim of the current protocol is to examine whether or not habitual use of medical marijuana affects psychomotor functioning operationalized as driving performance.
- Trial name
- ROADACE (NCT04629716)
- Testing
- Medical Cannabis
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Florida State University
Anesthesia; Functional
Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children
The aim of this prospective randomized study is to investigate comparatively the effect of neostigmine-atropine versus sugammadex on speed and quality of recovery and on postoperative cognitive function \& behavior in children…
- Trial name
- NCT02455921
- Testing
- neostigmine - atropine, Sugammadex
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Attikon Hospital
Mild Cognitive Impairment
Consumption of Potatoes, Avocados and Chickpeas and Cognitive Function in Older Adults
Cognitive impairment is also a major risk factor for development of dementia later in life. Findings from the investigators studies suggest that the carotenoids, lutein and zeaxanthin may be important in cognitive function in the…
- Trial name
- NCT01620567
- Testing
- avocado, potato or chickpea
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tufts University
Sarcopenia
Understanding Acute Sarcopenia
This study aims to characterise acute changes in muscle mass, strength, physical performance in hospitalised older adults. We will assess the impact of these changes upon physical function at three month follow-up, and assess for…
- Trial name
- NCT03858192
- Testing
- Colorectal surgery procedure, Emergency abdominal surgery, Antibiotics
- Where
- United Kingdom
- Volunteers
- 168 people
- Sponsor
- University of Birmingham
Elderly, Solid Malignancy
Geriatric Oncology Surgical Assessment and Functional rEcovery After Surgery
Multicenter, international, prospective, observational study, designed to evaluate the postoperative results in terms of quality of life and functional recovery of elderly patients after major cancer surgery.
- Trial name
- GOSAFE (NCT03299270)
- Testing
- Questionnaires
- Where
- 28 sites in United States, Greece and 8 more
- Volunteers
- 1,004 people
- Sponsor
- AUSL ROMAGNA
Geriatrics Rehabilitation
Effect of Modified Poco-Poco Exercise to Cognitive Function and Quality of Life in Elderly
Subjects with sarcopenia will get a modified poco-poco exercise program was assessed for tongue strength, cognitive function, and quality of life
- Trial name
- NCT07029321
- Testing
- Modified poco-poco exercises
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Padjadjaran
Multidomain Intervention
Effects of Passive Lower-limb Exoskeleton-assisted Training on Motor and Daily Function Improvements in Older Adults
According to National Development Council estimation, Taiwan is about to enter a super-aged society in 2025, and health promotion for the elderly are critical issues nowadays.
- Trial name
- NCT06543888
- Testing
- passive exoskeleton- assisted gait training programs, Conventional gait training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Aging, Postoperative Cognitive Dysfunction
Postoperative Cognitive Function and EEG
In the elderly patients undergoing elective non-cardiac major surgery, the differences of EEG parameters between those with and without postoperative cognitive dysfunction were observed to determine the characteristic changes of…
- Conditions
- Aging, Postoperative Cognitive Dysfunction, EEG With Periodic Abnormalities
- Trial name
- POEM (NCT04219033)
- Testing
- EEG(Electroencephalogram) change
- Where
- 18 sites in China
- Volunteers
- 1,250 people
- Sponsor
- Air Force Military Medical University, China
Oral Health, Oral Health Related Quality of Life
Oral (Hypo-)Function, General Function and Nutritional Status in Elderly Hospitalized Patients
The goal of this observational study is to learn about the effects of a reduced oral function on the nutritional status of non-acute hospitalized elders and on their oral health quality of life.
- Conditions
- Oral Health, Oral Health Related Quality of Life, Nutrition Disorders in Old Age
- Trial name
- Ohyp (NCT06557226)
- Testing
- oral and nutritional examination
- Where
- 2 sites in Switzerland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Elderly, Healthy
Agility Training on Physical Performance, Cognitive Function and Brain Activities in Elderly
Agility comprised of cognitive and physical functions, which influences whole-body movement with change of speed and direction. Agility training is widely used in athletes, and recent studies have begun to apply it into the…
- Trial name
- NCT05531396
- Testing
- Agility Training, Health Education
- Where
- Taiwan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Blood Pressure
The Effect of Whey Protein Supplementation on Vascular and Cognitive Function in Older Adults
The "hardening of the arteries" observed with aging raises blood pressure and contributes to poor brain blood flow and loss of cognitive function (i.e. attention, memory, solving problems, making decisions).
- Trial name
- NCT01956994
- Testing
- Whey protein supplement, Carbohydrate supplement
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Cognitive/Functional Effects, Depression
Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer
RATIONALE: Gathering information from older patients with newly diagnosed cancer may help doctors learn more about the risks of functional decline.
- Conditions
- Cognitive/Functional Effects, Depression, Hematopoietic/Lymphoid Cancer, Malnutrition
- Trial name
- NCT00769951
- Testing
- medical chart review, questionnaire administration, cognitive assessment
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Case Comprehensive Cancer Center
Elderly, Mild Cognitive Impairment
Binaural Beats and Cognitive Physical Dual-task Training for Enhancing Cognitive Function in Older Adults With Mild Cognitive Impairment
Mild cognitive impairment is a typical trasnitional stage betweeen the normal aging process and the onset of dementia. Mental exercises and aerobic exercises can shield brain from cognitive decline in elderly.
- Trial name
- NCT07110870
- Testing
- Cognitive Physical Dual task training, Binaural Beats and Cognitive physical dual task training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Foundation University Islamabad
Vascular Health
FLAVIOLA Health Study
Atherosclerosis progressively occurs with increasing age in the general population. So far most dietary intervention studies with flavanols were performed over short time frames and in small groups of young healthy and older…
- Trial name
- FHS (NCT01799005)
- Testing
- Flavanol (410 mg), Control (no flavanols)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Metabolism - Cerebral Energy
The Efficient Brain Study
Cerebral energy metabolism declines with advanced aging, and is implicated in age-related cognitive decline, Alzheimer's disease (AD), and other forms of neurodegenerative disease (Parkinson's disease).
- Trial name
- NCT02771366
- Testing
- Fermented Papaya Preparation, Granulated Sugar
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
COVID-19, Hemodiafiltration
Immune Function in Elderly Patients With Mild to Moderate COVID-19 on Hemodialysis
This randomized controlled trial will focus on the effects of early oral nutritional supplementation on immune function in elderly patients with mild to moderate COVID-19 on maintenance hemodialysis.
- Trial name
- NCT05366205
- Testing
- Oral nutritional supplement, Nutrition consultation
- Volunteers
- 112 people
- Sponsor
- Ruijin Hospital