Clinical trials: Physical Functional Impairment
HIV-1 Infection
PREPARE (A5361s) Ancillary Study of REPRIEVE (A5332)
Aging with HIV is associated with earlier development of frailty (weakness) or disability, including loss of physical and muscle strength, and walking speed.
- Trial name
- PREPARE (NCT03070223)
- Testing
- Pitavastatin
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 602 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Renal Impairment
Assessment of Renal Function by Multiparametric MRI
Metabolic syndrome is a collection of conditions that affect at least three of the following five criteria: abdominal obesity, high blood pressure, high fasting glucose levels, high triglyceride levels, and low levels of…
- Trial name
- NCT06407375
- Testing
- mpMRI
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Zurich
HIV Associated Neurocognitive Disorder
Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder
The purpose of this study is to see if paroxetine and fluconazole are safe and effective as a treatment for problems with memory, concentration, thinking, and judgment in people who are infected with HIV.
- Trial name
- ParaFlu (NCT01354314)
- Testing
- Fluconazole, Paroxetine, Paroxetine and Fluconazole
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins University
Arthritis, Pain
Non-cancer Pain and Cognitive Impairment: A Disabling Relationship
To compare the efficacy of long-acting oxycodone to extended-release acetaminophen in older persons with no and mild to moderate cognitive impairment and persistent moderate or higher intensity non-cancer lower extremity…
- Conditions
- Arthritis, Pain, Cognitive Impairment
- Trial name
- NCT01264965
- Testing
- long acting oxycodone, extra strength acetaminophen
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Chicago
Respiratory Insufficiency, Depression
Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respiratory Failure
More and more people are surviving after receiving life support for respiratory failure in the intensive care unit, but these patients often experience problems with depression and physical functioning that lead to reduced…
- Conditions
- Respiratory Insufficiency, Depression, Rehabilitation, Critical Care
- Trial name
- BEHAB (NCT03431493)
- Testing
- Behavioral Activation - Rehabilitation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Johns Hopkins University
Renal Impairment
Pharmacokinetic Assessment of Sodium Sulfide in Subjects With Impaired Renal Function
This is a Phase 1 study to assess the pharmacokinetics (PK) of IK-1001 (sodium sulfide) in healthy volunteers as well as in subjects with varying degrees of impaired renal function.
- Trial name
- NCT00879645
- Testing
- Sodium Sulfide
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mallinckrodt
Osteoarthritis, Knee, Quality of Life
Yoga for Managing Knee Osteoarthritis in Older Women: a Feasibility Study
The study hypothesized that it is feasible and safe to use Hatha yoga in older women with knee osteoarthritis (OA), and practicing Hatha yoga regularly will help reduce pain and stiffness, enhance physical function, and improve…
- Conditions
- Osteoarthritis, Knee, Quality of Life, Poor Quality Sleep, Physical Impairment
- Trial name
- NCT01832155
- Testing
- Hatha yoga
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Motor Activity, Health Behavior
Targeting Physical Activity to Improve Cardiovascular Health in Type 2 Diabetes
This study plans to learn more about physical activity and physical function in sedentary older adults with type 2 diabetes.
- Conditions
- Motor Activity, Health Behavior, Diabetes Mellitus, Type 2
- Trial name
- NCT02473926
- Testing
- Physical Activity, Questionnaires
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Colorado, Denver
Cerebral Palsy, Child, Preschool
Effect of Power Wheelchairs on the Development and Function of Young Children With Severe Physical Disabilities
Self-produced locomotion often is limited in children with cerebral palsy and other conditions that cause severe motor impairments.
- Trial name
- NCT01115998
- Testing
- Power wheelchair, No power wheelchairs
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Physical Disability, Cognitive Impairment
Improving Aging in Place in Subsidized Housing
This pilot study will evaluate the feasibility and preliminary effectiveness of an adapted version of the Function Focused Care intervention, delivered by telephone, for improving aging in place for older adults living in…
- Conditions
- Physical Disability, Cognitive Impairment, Physical Activity
- Trial name
- NCT04212442
- Testing
- Independent Living Program for Affordable Housing.
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania