Clinical trials: Physical Health
Stroke, Physical Activity
Activating Behavior for Lasting Engagement After Stroke
Stroke survivors demonstrate high levels of sedentary behavior, placing them at risk for exacerbation of chronic health conditions. This may lead to recurrent stroke.
- Conditions
- Stroke, Physical Activity, Sedentary Lifestyle, Behavior, Health
- Trial name
- ABLE (NCT03305731)
- Testing
- Activating Behavior for Lasting Engagement
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Pittsburgh
Mental Disorder in Adolescence
Personalized Assessment of Client Experiences
The purpose of this study is to compare two clinical approaches to youth mental health care.
- Trial name
- PACE (NCT04369924)
- Testing
- Unidimensional Measurement-Based Care, Multidimensional Measurement-Based Care
- Where
- United States
- Volunteers
- 1,261 people
- Sponsor
- University of Miami
Post-Mastectomy Chronic Pain Syndrome
Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Post-mastectomy pain due to nerve injury leads to long-term opioid use and diminished quality-of-life. The investigators on this study will evaluate the regenerative peripheral nerve interface (RPNI), a novel surgical approach to…
- Trial name
- RPNI (NCT04530526)
- Testing
- Regenerative Peripheral Nerve Interface
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan Rogel Cancer Center
Mental Illness, Physical Illness
Evaluation of Peer Specialists on VA PACTs
In August 2014, the White House issued an Executive Action mandating that 25 VA medical centers place Peer Specialists (Veterans recovered from mental illness who are trained to support other Veterans with mental illness) on…
- Trial name
- Peers on PACT (NCT02732600)
- Testing
- Facilitated Implementation
- Where
- 25 sites in United States
- Volunteers
- 5,616 people
- Sponsor
- VA Office of Research and Development
Contraception
Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience
The primary objective of this mixed methods pilot study is to understand women's experiences with postplacental intrauterine device (IUD) insertion through postpartum semi-structured interviews.
- Trial name
- PIPPI (NCT02312726)
- Testing
- Postplacental IUD insertion
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Overweight and Obesity
Rapid Evaluation of Innovative Intervention Components to Maximize the Health Benefits of Behavioral Obesity Treatment Delivered Online: An Application of Multiphase Optimization Strategy
When delivered online, behavioral obesity treatments have the potential to reach large numbers of individuals with overweight/obesity and produce significant improvements in health and wellbeing.
- Trial name
- NCT04520256
- Testing
- Online Behavioral Weight Loss Program, Virtual Reality for Behavioral Weight Loss Skills Training, Tailored Interactive Video Feedback
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- The Miriam Hospital
Coronary Heart Disease, Susceptibility to, 5, Prediabetic State
Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease
The purpose of this study is to examine whether the use of genetic test information and/or health coaching in patient risk counseling for heart disease and diabetes affect health behaviors and health outcomes in active-duty Air…
- Trial name
- NCT01884545
- Testing
- Health coaching, Genetic risk counseling, Standard risk assessment
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Duke University
Contraception, Inhalation of Nitrous Oxide
Nitrous Oxide for Pain Management During In-office Transcervical Sterilization
This is a randomized, double blind study that aims to measure the difference in maximum pain experienced during in-office transcervical sterilization (Essure®) for women receiving either inhaled nitrous oxide or standard oral…
- Trial name
- NEST (NCT02312739)
- Testing
- In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Sedentary Employees
Way to Be Active I (Teams)
Employers are increasingly looking for opportunities to motivate sedentary employees to become more physically active. Workplace walking programs have had mixed success and typically show most improvement among participants that…
- Trial name
- NCT02001194
- Testing
- Individual Incentives, Team Incentives, Individual plus Team Incentives
- Volunteers
- 304 people
- Sponsor
- University of Pennsylvania
Alcoholism
Examination of Zinc, S-adenosylmethionine, and Combination Therapy Versus Placebo in Alcoholics
This is a randomized, placebo controlled trial of dietary zinc and S-adenosylmethionine (SAMe) in otherwise healthy alcoholic US Veterans.
- Trial name
- ExZACTO (NCT01899521)
- Testing
- Bronchoscopy, Zinc sulfate 220 mg once daily, S-adenosylmethionine 400 mg twice daily
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- VA Office of Research and Development
Sedentary Employees
Way to Be Active 2 (Lotteries)
Employers are increasingly looking for opportunities to motivate sedentary employees to become more physically active. Workplace walking programs have had mixed success and typically show most improvement among participants that…
- Trial name
- NCT02005276
- Testing
- Basic Lottery, Combined Lottery, Jackpot Lottery
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- University of Pennsylvania
Overweight and Obesity, Health Behavior
Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II
College students are in a newly independent phase of life; many of whom encounter unhealthy dietary decision- making, barriers to physical activity, and poor sleep behaviors.
- Conditions
- Overweight and Obesity, Health Behavior, Sleep Deprivation
- Trial name
- NCT02996864
- Testing
- Healthy Detours App, Fat Secret App
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Obesity
Coaching Veterans to Healthy Weights and Wellness
ASPIRE has completed enrollment of patients at the Ann Arbor and Cleveland Medical Centers in a study that is examining the impact of an innovative approach to weight loss ("Aspiring to Lifelong Health in VA", aka "ASPIRE-VA").
- Trial name
- ASPIRE (NCT00967668)
- Testing
- Small change approach to improve physical activity and diet, MOVE! Usual Care
- Where
- 2 sites in United States
- Volunteers
- 481 people
- Sponsor
- US Department of Veterans Affairs
Patient Participation, Pediatric ALL
Inclusion Appeal Videos and Intent to Register for Pediatric Clinical Trials
An informational video about joining a Research Notification Registry is being compared with a version of the video tailored to African/ African American parents, reminding them about the importance of their being included in…
- Trial name
- NCT06138145
- Testing
- Video, Survey
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Nutritional Assessment
Validity of the PortionSize App to Measure Children's Food Intake
The purpose of this study is to assess the validity of the PortionSize™ app to quantify children's own dietary intake and children's intake by parents or caregivers.
- Trial name
- NCT05587816
- Testing
- Validation of the PortionSize app
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Sedentary Behavior, Cognitive Impairment
A Physical Activity Program to Disrupt Sedentary Time in Older Latinos
To test the feasibility of an intervention designed to replace sedentary time with physical activity in older Latinos, delivered in their homes to improve cognitive function and brain connectivity.
- Trial name
- PAIS (NCT04507464)
- Testing
- Ecological Momentary Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Rheumatoid Arthritis, Cardiovascular Diseases
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk…
- Conditions
- Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
- Trial name
- CARE RA (NCT04488497)
- Testing
- Cardiovascular Risk Assessment for Patients with Rheumatoid Arthritis, Standard of care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cancer
A Web-Based Physical Activity Intervention in Adolescent Survivors of Childhood Cancer
Five year survival following a diagnosis of childhood cancer has reached 83%, making long term health outcomes among survivors an important concern.
- Trial name
- NCT01778127
- Testing
- Activity Monitor, Interactive Website, Educational Materials
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- St. Jude Children's Research Hospital
Breast Cancer, Colorectal Cancer
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health
This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial…
- Conditions
- Breast Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer
- Trial name
- AMPLIFY (NCT04000880)
- Testing
- Adapting MultiPLe Behavior Interventions That eFfectively Improve (AMPLIFI) Cancer Survivor Health, Diet-Exercise, Exercise-Diet
- Where
- 2 sites in United States
- Volunteers
- 603 people
- Sponsor
- University of Alabama at Birmingham
Female Sexual Dysfunction, Female Sexual Dysfunction Due to Physical Condition
Effect of Peripheral Neuromodulation on Vaginal Blood Flow - Study 2
The overall purpose of this research is to improve sexual function in women with sexual dysfunction. The goal of this study is to see if either of two nerve stimulation interventions cause a short-term change in vaginal blood…
- Trial name
- NCT06999265
- Testing
- Transcutaneous electrical nerve stimulation - Tibial Nerve, Transcutaneous electrical nerve stimulation - Genital Nerve, Neutral and Erotic Film Clip Alternation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Michigan