Clinical trials: Physical Illness
Sepsis, Septic Shock
Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey
The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of sepsis in adult patients admitted to Intensive Care Units (ICUs) in…
- Conditions
- Sepsis, Septic Shock, Critical Illness, Organ Dysfunction
- Trial name
- TURK-SOFA2 (NCT07300306)
- Where
- Turkey (Türkiye)
- Volunteers
- 3,379 people
- Sponsor
- Marmara University
Cancer, Kidney Diseases
Patient Reported Unmet Needs for Function and Supportive Occupational- and Physiotherapy Rehabilitation Interventions
Purpose: To determine unmet functional needs in patients referred to the Palliative Care Unit at Rigshospitalet, Copenhagen University Hospital will be asked to fill out self reported questionnaires regarding problem intensity…
- Conditions
- Cancer, Kidney Diseases, Heart Failure, Neurologic Disorder
- Trial name
- NCT04066153
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Musculoskeletal Pain Disorder
Risk Assessment for Prolonged Sickness Absence Due to Musculoskeletal Conditions
Musculoskeletal (MSK) conditions are a leading cause of years lived with disability worldwide and for the last decade they have also been the most common cause of sickness absence and disability pension in Norway.
- Trial name
- NCT04196634
- Testing
- Risk assessment
- Where
- Norway
- Volunteers
- 560 people
- Sponsor
- Oslo Metropolitan University
COVID 19
Convalescent Plasma for COVID-19 Patients (CPCP)
Prior findings in various viral respiratory diseases including SARS-CoV-related pneumonia suggest that convalescent plasma can reduce mortality, although formal proof of efficacy is still lacking.
- Trial name
- CPCP (NCT04521036)
- Testing
- Convalescent Plasma as Therapy for Covid-19 patients
- Where
- Vietnam
- Volunteers
- 4 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Intensive Care Unit, Muscle Strength
Normative Values for Peripheral Muscle Strength in Critical Patients and Healthy Individuals
Muscle strength is an important indicator of overall health and is a factor that has been associated with increased mortality in critical patients.
- Trial name
- HHD-ICU (NCT06296381)
- Where
- 4 sites in Brazil
- Volunteers
- 180 people
- Sponsor
- University of Pernambuco
Depressive Disorder, Somatoform Disorder
Physical Activity in Insurance Medicine: Effects on Patients With Psychiatric Disorders
We will conduct a randomized control trial to investigate whether and to what extent regular and guided group physical activity over 12 weeks (2 sessions à 1 hour/week) improves physical fitness and (physio-)psychological…
- Conditions
- Depressive Disorder, Somatoform Disorder, Anxiety Disorder, Personality Disorder
- Trial name
- PhysActIV (NCT01928264)
- Testing
- Physical activity
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Basel, Switzerland
Inflammatory Bowel Disease, Ulcerative Colitis
Understanding and Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
This research will examine the impact of brain activity, cognitive processing immune functioning, and gastrointestinal functioning on depressive symptoms and response to a psychotherapeutic intervention in youths with…
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease, Depression
- Trial name
- NCT00769353
- Testing
- Primary and Secondary Coping Enhancement Training, Supportive Non-directive Therapy
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Disease, Life-limiting Illness
Quality of Life Assessment and Practice Support System in Home Care Services for Older Adults
Older adults living with incurable and advancing life-limiting illness frequently desire to spend as much time as possible comfortably at home, rather than in hospital.
- Conditions
- Chronic Disease, Life-limiting Illness, Palliative Care
- Trial name
- QPSS (NCT02940951)
- Testing
- QPSS, Usual care
- Where
- 2 sites in Canada
- Volunteers
- 565 people
- Sponsor
- Trinity Western University
Critical Illness, Physical Disability
Neuromuscular Electrical Stimulation (NMES) Preserves Muscle Mass in Intensive Care Unit (ICU)
Background: Low-frequency neuromuscular electrical stimulation (NMES) attenuates the loss of muscle mass of Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Physical Disability, Muscle Atrophy
- Trial name
- NCT05287919
- Testing
- Patients received the standard physical therapy (SPT) programme (passive mobilization) twice a day., Patients received the low-frequency neuromuscular electrical stimulation (NMES), Patients received the medium-frequency neuromuscular electrical stimulation (NMES)
- Where
- Chile
- Volunteers
- 54 people
- Sponsor
- Gabriel Nasri Marzuca-Nassr
Critical Illness
Parenteral Nutrition With Intravenous and Oral Fish Oil for Intensive Care Patients
The primary objective is to assess the effect of fish oil-enriched enteral and parenteral nutrition on blood oxygenation in critically ill patients.
- Trial name
- NCT01162928
- Testing
- Nutriflex Omega special + Oxepa, Nutriflex Lipid special + Pulmocare
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- B. Braun Melsungen AG
Critical Illness
Assessment of Hemodynamic Responses at Adequate Depth of Anesthesia Using Bispectral Index During Rapid Sequence Intubation in the Emergency Department
Rapid sequence intubation (RSI) is the standard approach for emergency airway management in critically ill patients requiring endotracheal intubation.
- Trial name
- NCT07722897
- Testing
- Bispectral Index (BIS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Akdeniz University Hospital
Critical Illness, Muscle Weakness
Relationship Between Muscle Strength and Physical Function in ICU
This observational study aims to assess the relationship between muscle strength and physical function in critical ill patients. Grip and quadriceps strengths are measured using a standardized protocol of dynamometry.
- Conditions
- Critical Illness, Muscle Weakness, Physical Disability, Physical Dependence
- Trial name
- NCT04284475
- Testing
- Quadriceps strength, Grip strength, ICU mobility scale
- Where
- Belgium
- Volunteers
- 93 people
- Sponsor
- University of Liege
Pelvic Floor Disorders, Ultrasound Therapy; Complications
Role of Rehabilitation for the Repair of Pelvic Floor Injuries Associated to Vaginal Delivery Identified by 3/4D Transperineal Ultrasound
SUMMARY: (Objective, design, scope of the study, subjects of study, instrumentation, results, conclusions) Objectives: To evaluate if the physiotherapy treatment in pelvic floor dysfunctions, identified by transperineal…
- Conditions
- Pelvic Floor Disorders, Ultrasound Therapy; Complications, Physical Disorder, Obstetric Labor Complications
- Trial name
- NCT03592160
- Testing
- Physiotherapy treatment
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital Universitario de Valme
Exercise Therapy, Behavior and Behavior Mechanisms
Health-Enhancing Adapted Physical Activity Program at "Mon Stade"
Introduction: Regular practice of exercise or physical activity (PA) is a recognized intervention as a determinant of good health acquisition, maintenance, or recovery for a large number of chronic pathologies.
- Conditions
- Exercise Therapy, Behavior and Behavior Mechanisms, Adherence, Patient, Lifestyle, Sedentary
- Trial name
- SESAME (NCT04716322)
- Testing
- Adapted Physical Activity
- Where
- France
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Mon Stade Sports Medicine Centre
Stroke, Post-Stroke Cognitive Impairment (PSCI)
Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment
This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy.
- Conditions
- Stroke, Post-Stroke Cognitive Impairment (PSCI), Cognitive Dysfunction, Virtual Reality Therapy
- Trial name
- NCT07125170
- Testing
- Kinesix XR on Meta Quest 3
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Somatoform Disorders
Treatment of Medically Unexplained Physical Ailments (Somatization Disorder)
The purpose of this study is to compare cognitive behavior therapy (CBT) to medical care-as-usual for the treatment of patients with high levels of medically unexplained physical symptoms (Somatization Disorder).
- Trial name
- NCT00050583
- Testing
- Cognitive Behavioral Therapy, CBT
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Pain, Pain Management
Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustments
Both severe pain and opioid therapy are associated with negative effects. The experience of pain is common in the intensive care unit, but it is highly individual and difficult to assess, as patients are often unable to…
- Conditions
- Pain, Pain Management, Critical Illness
- Trial name
- INVISIBLE (NCT07473115)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Critical Illness, Post Intensive Care Syndrome (PICS)
Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)
This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS).
- Conditions
- Critical Illness, Post Intensive Care Syndrome (PICS), Cardiopathy
- Trial name
- CARDIO-PICS (NCT07599306)
- Testing
- Tele-rehabilitation, Standard of Care
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Critical Illness, Delirium in the Intensive Care Unit
Digital and Plasma Biomarkers in Delirium
The goal of this observational study is to learn if there are potential digital and plasma-based biomarkers that could help detect, predict, and prognosticate delirium in older adult patients who are admitted to the intensive…
- Conditions
- Critical Illness, Delirium in the Intensive Care Unit, Sleep Quality
- Trial name
- DELTA (NCT07694206)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Scripps Health
Critical Illness, COVID-19
Neurocognitive Impairment in Patients With COVID-19
Delirium and acute neurocognitive impairment are increasingly observed in adult and pediatric patients with COVID-19. Prospective clinical studies combining clinical and laboratory examinations including specific biomarkers of…
- Conditions
- Critical Illness, COVID-19, Central Nervous System Injury, Delirium
- Trial name
- NCoV (NCT04359914)
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- University of Rostock