Clinical trials: Physical Illness
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito: 2850m) to sea level on six-minute walking distance and scores in patients with pulmonary arterial hypertension PAH, who live permanently >2600m.
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, Six-minute Walk Test, High Altitude Effects
- Trial name
- NCT07804472
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Respiratory Tract Infections (RTI), Influenza-like Illness
Clinical Assessment of Respiratory Events for Kids: Integrating Diagnostics and Stewardship
This study, called Care4Kids, aims to improve the management of respiratory infections in children visiting emergency departments.
- Conditions
- Respiratory Tract Infections (RTI), Influenza-like Illness, Children
- Trial name
- CARE4KIDS (NCT07453914)
- Testing
- SPOTFIRE R
- Where
- 3 sites in France, Greece and 1 more
- Volunteers
- 720 people
- Sponsor
- BioMérieux
Critical Illness
Validation of the SD-ICU. A Risk Assessment Tool of Unplanned ICU Readmission
In a recent study, which included 845 patients that at the time of ICU discharge had at least one risk factor for readmission, the investigators' group developed a new readmission risk score in the ICU, Safe Discharge from ICU…
- Trial name
- NCT02330874
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- Hospital Sao Domingos
Covid19, Sequelae of; Infection
Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
The study will assess whether Niagen, a safe dietary supplement, improves recovery of COVID-19 related symptoms in individuals who were infected at least 2 months prior to study entry ("Long-COVID" "Long-haulers").
- Conditions
- Covid19, Sequelae of; Infection, Cognitive Symptom
- Trial name
- NCT04809974
- Testing
- Niagen
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Cannabis Use Disorder, Mental Health Disorder
Regulated Cannabis Access in Basel
The randomised controlled study on regulated cannabis access in pharmacies in Basel aims to investigate the effects of regulated cannabis access on consumption behaviour and mental and physical health in comparison to the illegal…
- Conditions
- Cannabis Use Disorder, Mental Health Disorder, Physical Illness
- Trial name
- NCT05522205
- Testing
- Regulated cannabis access in pharmacies
- Where
- Switzerland
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Health Department of the Canton of Basel-Stadt
Neuromuscular Blockade, Critical Illness
Pharmacological Reversal of Neuromuscular Blockade in Critically Ill Patients
The goal of this clinical trial is to compare the effect of use of reversal agents for neuromuscular blockade in critically ill patients on time for neurological assessment after endotracheal intubation The main questions it aims…
- Conditions
- Neuromuscular Blockade, Critical Illness, Neurologic Findings
- Trial name
- NCT05993390
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Critical Illness
Clinical Characteristics and Discharge Assessment of Patients From Palliative Care
The number of people having chronic diseases and the demand for palliative care has increased. The factors that have an impact on length of stay and discharge of patient who were admitted to palliative care center will be…
- Trial name
- NCT04755374
- Testing
- Discharged ≤ 21 days, Prolonged discharge
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Pediatrics, Critical Illness
Construction and Application of the Visualization Training Platform Based on a Multimodal Standardized Dataset for Pain Assessment in Critically Ill Children
The goal of this clinical trial is to learn if the visualization training platform based on a multimodal standardized dataset for pain assessment in critically ill children is applicable for pain assessment training.
- Conditions
- Pediatrics, Critical Illness, Pain Measurement
- Trial name
- NCT06431802
- Testing
- Conventional intervention, Platform intervention
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Ketogenic Dieting, Altitude Hypoxia
Effect of Isocaloric Ketogenic Diet on Physical Performance at High Altitude
A ketogenic diet (KD) reduces daily carbohydrates (CHOs) ingestion by replacing most calories with fat. KD is of increasing interest among athletes because it may increase their maximal oxygen uptake (VO2max), the principal…
- Conditions
- Ketogenic Dieting, Altitude Hypoxia, Physical Activity
- Trial name
- ICKD (NCT05603689)
- Testing
- Isocaloric ketogenic diet
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Clinique Romande de Readaptation
Post-Intensive Care Syndrome (PICS), Critical Illness Recovery
Virtual Reality for Recovery After Intensive Care (PICS)
The goal of this clinical trial is to learn if virtual reality (VR) helps improve thinking and memory skills in adults who have stayed in the intensive care unit (ICU).
- Conditions
- Post-Intensive Care Syndrome (PICS), Critical Illness Recovery, Rehabilitation After Critical Illness, Rehabilitation Exercise of ICU Patients
- Trial name
- VR4ICU (NCT07585500)
- Testing
- Immersive VR Multi-Domain Rehabilitation, Tablet-Based Multi-Domain Training
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- University of Minho
Covid-19, Critical Illness
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Introduction: Survivors of acute respiratory failure develop persistent muscle weakness and deficits in cardiopulmonary endurance combining to limit physical functioning.
- Conditions
- Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
- Trial name
- OPTIMAL (NCT04412330)
- Testing
- ICU Recovery + Physical Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Kentucky
Chronic Physical Health Conditions
MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace
The specific aim of the study is to evaluate the health benefits of a series of group workshops designed for workers with chronic physical health conditions.
- Trial name
- NCT01978392
- Testing
- Self-management group workshops
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Heart Failure With Reduced Ejection Fraction, Atrial Fibrillation, Persistent
Pulmonary Artery Pressure and Right Heart Evaluation for Patients Requiring Physiological Pacing Treatment
With the aging of society, the use of cardiac pacing in patients with irreversible bradycardia is increasingly widespread. As early as the 1950s, right ventricular pacing (RVP) began to be used in patients with atrioventricular…
- Conditions
- Heart Failure With Reduced Ejection Fraction, Atrial Fibrillation, Persistent, Sick Sinus Syndrome, Atrioventricular Block
- Trial name
- NCT05575557
- Testing
- Right heart catheterization
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Cardiovascular Diseases, Respiratory Diseases
Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children
This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age…
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Mental Health Disorders, Heat Illness
- Trial name
- NCT07643571
- Testing
- WeChat Mini-program Based Heat Health Risk Early Warning Intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Nutrition Assessment, Critical Illness
Indirect Calorimetry: SensorMedics Vmax vs GE Carescape - a Method Comparison Study
Dosing of nutrition in PICUs is mainly based on patient weight and assumptions on clinical status. There is however poor correlation between these calculations and actual energy consumption measured with indirect calorimetry…
- Conditions
- Nutrition Assessment, Critical Illness, Children
- Trial name
- NCT02987309
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Oslo University Hospital
Fall Patients, Pain
Physiotherapy in Emergency Department: a Service Analysis From a French Hospital
The skills of physiotherapists have been employed to enhance access to optimal care in Emergency Departments (ED). No study has yet been conducted on the practices in France.
- Conditions
- Fall Patients, Pain, Sprains, Respiratory Insufficiency
- Trial name
- NCT06528899
- Testing
- Physical Therapy
- Where
- 2 sites in France
- Volunteers
- 461 people
- Sponsor
- Université de Nantes
Chronic Obstructive Pulmonary Disease, Asthma
Sickness Absence Versus Physical, Mental, and Job-related Factors in Patients With Chronic Pulmonary Disease
People with chronic respiratory disease have shortened work life, their disease is associated with greater work disability and they are at greater risk of being unemployed.
- Trial name
- NCT01118104
- Testing
- Vocational pulmonary rehabilitation
- Where
- Norway
- Volunteers
- 318 people
- Sponsor
- LHL Helse
Psychiatric Disorders, Common Mental Disorders
Prevalence and Effect of Detecting Common Mental Disorders in Long-term Sickness Absence
The hypothesis was that a large fraction of individuals with common mental disorders were undetected in long-term sickness and that detection of the disorders by screening, a psychiatric diagnostic examination and feedback to the…
- Conditions
- Psychiatric Disorders, Common Mental Disorders, Depression, Anxiety
- Trial name
- PRW (NCT01989728)
- Testing
- psychiatric examination and feedback
- Where
- Denmark
- Volunteers
- 1,121 people
- Sponsor
- Region MidtJylland Denmark
Mental Disorders
Physical Activity in Patients With Severe Mental Illness
The aim of the study was to evaluate the applicability of the Physical Activity Scale (PAS) in relation to patients with severe mental illness.
- Trial name
- NCT01329094
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Influenza, Influenza-like Illness
A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD
A total of 18,000 eligible subjects (or 6,000 subject distributed evenly between the 3 study arms) will be enrolled. Eligible subjects will be randomized in 1:1:1 (cell-culture-based vaccine, the recombinant vaccine, or the…
- Conditions
- Influenza, Influenza-like Illness, Influenza Vaccines
- Trial name
- PAIVED (NCT03734237)
- Testing
- Egg based influenza vaccines, Recombinant influenza vaccines, Cell-culture based influenza vaccines
- Where
- 9 sites in United States
- Volunteers
- 15,448 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine