Clinical trials: Physical Impairment
Patients Treated for Cancer
Cancer Related Cognitive Impairment
Various recent scientific data testify to the cognitive deficiencies of cancer patients, called Cancer-Related Cognitive Impairments (CRCI) (Noal, Daireaux \& Joly, 2010).
- Trial name
- APACO (NCT03949322)
- Testing
- Adapted Physical Activity Program
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Institut Cancerologie de l'Ouest
Subjective Cognitive Decline, Alzheimer Disease
Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns
AHEAD is a prospective, longitudinal, risk-stratified single-arm interventional study enrolling 300 patients with Subjective Cognitive Decline (SCD) at IRCCS San Raffaele Hospital, Milan, Italy.
- Conditions
- Subjective Cognitive Decline, Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
- Trial name
- AHEAD (NCT07652931)
- Testing
- High-frequency Transcranial Magnetic Stimulation (TMS), Digital Cognitive Training, Structured Physical Exercise
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele
Parkinson Disease, Cognitive Impairment
Physical Therapy and Cognitive Decline
Background: Mild Cognitive Impairment in Parkinson's disease (PD-MCI) is considered a predictor for the development of dementia, a major source of eventual treatment-refractory disability.
- Trial name
- PD-MCI (NCT04012086)
- Testing
- Physical therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Breast Cancer
Intellectual Impairment in Women With Breast Cancer
RATIONALE: Breast cancer and its treatment may cause changes in a patient's ability to think, learn, and remember. Gathering information about a woman's genes, brain function, and personal history may help doctors learn more…
- Trial name
- NCT00896324
- Testing
- Cognitive Rehabilitation, Active Neurofeedback Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Vision Disability
Assessment of an Augmented Reality Low Visual Aid in Children and Young People With Visual Impairment
Approximately 24,500 children and young people (CYP) in England have a visual impairment (VI). VI refers to a loss of vision that cannot be corrected with glasses or contact lenses. Low vision aids (e.g.
- Trial name
- NCT05201482
- Testing
- SightPlus
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Maculopathy
AVIGA3 (Cohort 2.0)
Age-Macular Degeneration (AMD) is a common eye condition and a leading cause of vision loss among people age 50 and older. It causes damage to the macula, a small area near the centre of the retina needed for sharp, central…
- Trial name
- AVIGA3 (NCT07255859)
- Testing
- Amsler Grid, AVIGA
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Tan Tock Seng Hospital
Diabetes, Prediabetes
The Usefulness of Postprandial Triglyceride for Assessment of Cardiovascular Risk
The hypertriglyceridemia at fasting status has been known to be an important risk factor for cardiovascular disease (CVD). Recently, postprandial triglyceride (TG) levels draw an attention as a superior predictor of CVD because…
- Trial name
- NCT01972542
- Testing
- Oral fat tolerance test
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Subarachnoid Hemorrhage, Delayed Cerebral Ischemia
Swiss SOS MoCA - DCI Study
The primary objective of this multicenter observational study is to determine the effect size of the relationship between DCI and neuropsychological impairment 14-28 days and 3 months after aSAH.
- Conditions
- Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, Stroke, Complication
- Trial name
- NCT03032471
- Testing
- There is no intervention for this study. Patients are allocated to the study groups based on whether or not DCI occurs.
- Where
- 6 sites in Switzerland
- Volunteers
- 128 people
- Sponsor
- Swiss SOS Study Group
Pain, Mental Health Impairment
Physiotherapy and Psychological Among Refugees From Syria
The war in Syria began in 2011 and refugees from this country have faced stressors including security risks, lack of access and availability of basic services and resources as well as family, community, and socio political…
- Trial name
- NCT03951909
- Testing
- Physiotherapy activity and awareness intervention: PAAI, Psychological intervention: Teaching recovery techniques (TRT)
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- University of Bergen
Frailty, Mild Cognitive Impairment
Influence of Square-stepping Exercise on Brain Activation, Cognitive Function and Physical Performance in Frail Elders With MCI
This study is to elucidate the possible mechanisms of SSE by examining brain activation differences between SSE patterns and usual walking, as well as the relationship between brain activity and SSE performance, between cognitive…
- Trial name
- NCT05173363
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Yang Ming Chiao Tung University
Insulin Resistance, Obesity
Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity
A combination of generally regarded as safe (GRAS) compounds named GLY-LOW, which included: alpha lipoic acid, pyridoxamine, nicotinamide, piperine and thiamine, were examined in pre-clinical experiments.
- Conditions
- Insulin Resistance, Obesity, Cardiovascular Diseases, Cognitive Impairment
- Trial name
- NCT06242535
- Testing
- GLY-LOW
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hoskinson Health and Wellness Clinic
Covid19, Neurological Disorder
COVID-19 Versus Neurological Impairment, Physical Activity, Social Contacts and Education
The research will make it possible to assess patients who recovered from COVID-19 for the incidence of neurological problems (impaired balance, gait, coordination, concentration and attention), and changes in the quality of life…
- Conditions
- Covid19, Neurological Disorder, Balance; Distorted, Gait Disorders, Neurologic
- Trial name
- NCT04934085
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Breast Cancer, Obesity
Remote Assessment of Cognition, Insulin Resistance and Omega-3 Fatty Acid Biomarkers in Breast Cancer Survivors
Majority of breast cancer survivors are overweight or obese at time of diagnosis, putting them at increased risk for insulin resistance and Type 2 Diabetes Mellitus (T2DM).
- Trial name
- RACIRO-3 (NCT05048108)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Communication Disorders
Adaptive and Individualized AAC
This project will test the feasibility of developing a smart augmentative or alternative communication (AAC) system that is effective in delivering communication capabilities that automatically adapt to the users' physical…
- Trial name
- NCT04247828
- Testing
- Experimental AAC, Generic AAC
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Coordination Impairment
Physical Activity on Eye Hand Coordination Post Strabismus Surgery
The aim of this study is to determine the effect of physical activity on eye hand coordination in patient with amblyopia after strabismus surgery.
- Trial name
- NCT06759792
- Testing
- eye hand coordination exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid
Exertional Heat Injury
Integrating Cognitive Assessments Into the Heat Tolerance Test After Exertional Heat Injury
This prospective observational study is to evaluate soldiers post-exertional heat injury (EHI) during a heat tolerant test (HTT) to investigate the impact on their cognitive performance.
- Trial name
- NCT06764264
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Medical Corps, Israel Defense Force
Renal Impairment
Assessment of Renal Function by Multiparametric MRI
Metabolic syndrome is a collection of conditions that affect at least three of the following five criteria: abdominal obesity, high blood pressure, high fasting glucose levels, high triglyceride levels, and low levels of…
- Trial name
- NCT06407375
- Testing
- mpMRI
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cognitive Impairment, Healthy Control
Prediction of MMSE Scores for Cognitive Impairment
This study aims to explore the potential of using machine learning (ML) algorithms to predict cognitive status, specifically MMSE scores, based on oral health and demographic data.
- Trial name
- NCT06611475
- Testing
- MMSE ≤26
- Where
- Sweden
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Inadequate or Impaired Respiratory Function, Diabetes
Effects of Respiratory Muscle Training in Obese Women
The objective of this study will be to evaluate the effects of inspiratory muscle training (IMT) on the physical fitness of obese women It is believed that the application of these exercises helps in the improvement of…
- Conditions
- Inadequate or Impaired Respiratory Function, Diabetes, Hypertension
- Trial name
- NCT03767556
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Treatment of Type I Diabetes Mellitus.
Dendritic Cells for Type 1 Diabetes Mellitus (T1DM) Therapy
Phase IB will evaluate the safety of autologous, ex vivo-engineered, co-stimulation impaired dendtritic cells to maintain and improve functional residual beta cell mass in new onset Type I Diabetes Mellitus (T1DM) patients.
- Trial name
- NCT01947569
- Testing
- Biological
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- DiaVacs, Inc.