Clinical trials: Physical Injury
Disorder of Consciousness, Traumatic Brain Injury
Validity and Feasibility of the CRSR-FAST
The CRS-R is a standardized and validated bedside assessment of conscious awareness. It is used routinely for diagnosis and prognosis of patients with disorders of consciousness (DOC) as well as in research settings.
- Trial name
- CRSR-FAST (NCT03549572)
- Testing
- Coma Recovery Scale-Revised
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Healthy Athlete
Movement Assessment for Concussion Management
Previous work in the area of concussion management has focused heavily on neuro-cognitive testing. In addition to routine neuro-cognitive testing through Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT),this…
- Trial name
- NCT02776904
- Testing
- Immediate Post-concussion Assessment and Cognitive Testing, Gait with single and dual task, Y-Balance test
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Non Small Cell Lung Cancer
Feasibility Study of Enhanced MRI for Early Stage Non Small Cell Lung Cancer (NSCLC)
This is a pilot study. A pilot study is done with a small number of participants to see if a technique works before using it in a larger research study.
- Trial name
- NCT01799135
- Testing
- DCE-MRI scan, Stereotactic Body Radiation Therapy, 4D-CT scan
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Dana-Farber Cancer Institute
Wounds and Injuries
Randomized Control Trial of Booster Seat Education Material to Increase Perceived Benefit Among Parents
Seat belts protect people from injuries by diverting crash forces to stronger anatomical structures: the rib cage and the pelvis.
- Trial name
- NCT03573830
- Testing
- Transport Canada material, Enhanced material
- Where
- Canada
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Osteoporotic Fractures, Osteoporosis, Postmenopausal
A 5-Year Follow-up Study Investigating Factors Associated With Osteoporotic Fracture in Chinese Postmenopausal Women
This proposed study was designed to investigate the prevalence of a 5-year incident osteoporotic fracture and evaluate the association of a 5-year change of 25-hydroxyvitamin D (25[OH]D)/bone turnover makers/bone mineral density…
- Trial name
- PK-VF (NCT02247011)
- Testing
- Questionaire survey, Bone mineral density examination, Vertebral fracture assessment
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Displaced Ankle Fractures
Assessment of Ability of 3D Fluorscopy in Aiding Accurate Syndesmotic Reduction Following Traumatic Ankle Injury
The purpose of this study is to determine if use of new imaging technology termed "3D fluoroscopy" will lead the surgeon to change the position of the fractured bones to a more accurate position.
- Trial name
- NCT03163017
- Testing
- 2D Fluoroscopy, 3D Fluoroscopy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Injuries
The Use of Public Messaging for the Promotion of Firearm Safety to Veterans
This pilot study seeks to determine if exposure to the firearm safety public service announcement (PSA) developed by the U.S. Department of Veterans Affairs (VA) is associated with changes in related beliefs and safe storage…
- Trial name
- NCT03417752
- Testing
- Exposure to firearm safety PSA, Exposure to health promotion PSA
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- Canandaigua VA Medical Center
Brain Concussion, Blast Injuries
Metacognitive Training to Enhance Strategy Use in Blast-Related TBI
Enhanced Goal Management Training (GMT) is a 10-week group or individual therapy that teaches strategies to improve an individual's ability to complete everyday tasks.
- Trial name
- NCT00857207
- Testing
- Goal Management Training
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Spina Bifida
Virtual Reality Based Testing of Power Wheelchair Driving Skills
The purpose of this research study is to examine whether computer based or virtual reality based driving assessments are as useful as real-world power wheelchair driving tests in measuring driving performance and whether they may…
- Conditions
- Spinal Cord Injury, Spina Bifida, Spinal Cord Disease
- Trial name
- NCT00951509
- Testing
- Power Mobility Road Test (PMRT)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- US Department of Veterans Affairs
Wound Healing
A Test of Different Kinds of Bandages on Healing of Wounds
This two-week study will compare the healing of minor wounds when no bandage is applied against four different types of bandages.
- Trial name
- NCT01770860
- Testing
- 6660, 4314, 8336
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Products Company Division of Johnson & Johnson Consumer Companies, Inc.
Physical Frailty, Hip Fracture
Exercise and Testosterone Therapy in Elderly Men With Physical Frailty
The primary aim of this study is to determine, in hypogonadal older men with physical frailty, whether exercise training combined with testosterone replacement therapy can improve skeletal muscle strength, and lean mass, to a…
- Conditions
- Physical Frailty, Hip Fracture, Elective Hip Replacement, Hypogonadism
- Trial name
- NCT00345969
- Testing
- Transdermal Testosterone gel (1%), Supervised exercise training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Washington University School of Medicine
Diabetic Foot Ulcers, Pressure Ulcers
Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds
To compare HP828-101 to standard of care for the management of partial or full thickness wounds
- Trial name
- NCT00971048
- Testing
- HP828-101, Hydrogel/Hydrocolloid
- Where
- 11 sites in United States
- Volunteers
- 88 people
- Sponsor
- Healthpoint
Anterior Cruciate Ligament Injuries, Exercise
Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion
Osteoarthritis (OA) is a leading cause of disability worldwide that affects millions of Americans each year. Posttraumatic OA (PTOA) significantly impacts patients after anterior cruciate ligament (ACL) injury and ACL…
- Conditions
- Anterior Cruciate Ligament Injuries, Exercise, Cartilage, Articular, Knee Injuries
- Trial name
- NCT04906499
- Testing
- Physical Activity Promotion
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of North Carolina, Chapel Hill
Wound Healing
Assessment Of Infrared Photobiotherapy for Improved Wound Healing
The purpose of this study is to examine whether or not Low Level Laser Therapy (LLLT) can reduce pain and/or improve wound healing in patients with an acute traumatic injury to the upper extremity (wrist, forearm, or elbow).
- Trial name
- NCT00426166
- Testing
- Low Level Laser Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Toledo Health Science Campus
Lung Injury, Acute
SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS
This is an early phase (Phase IIa), randomized, double-blind, parallel group, multi-centre study for subjects with trauma (physical injury) who are at risk for developing Acute Lung Injury (ALI) or Acute Respiratory Distress…
- Trial name
- NCT00996840
- Testing
- SB-681323 Intravenous 3mg, SB-681323 Intravenous 7.5 mg, SB-681323 Intravenous 7.5mg
- Where
- 6 sites in United States
- Volunteers
- 77 people
- Sponsor
- GlaxoSmithKline
Anterior Cruciate Ligament (ACL) Tear, Physical Therapy
The Effect of Various Strength Training Protocols in ACL Reconstructed Participants
The purpose of the study is to determine how two different blood flow restriction training programs used in conjunction with standard rehabilitation affect leg strength.
- Trial name
- NCT03364647
- Testing
- Arm A - blood flow restriction training, Arm B - standard of care
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Brian W. Noehren
Stroke, Traumatic Brain Injury
Informal Caregivers ANSWERS-VA
The purpose of this study is to determine the effectiveness of the ANSWERS- VA intervention (Acquiring New Skills While Enhancing Remaining Strengths for Veterans) while also determining it's cost effectiveness in the stroke and…
- Trial name
- NCT02398409
- Testing
- ANSWERS - Acquiring New Skills While Enhancing Remaining Strengths, Control
- Where
- 2 sites in United States
- Volunteers
- 143 people
- Sponsor
- VA Office of Research and Development
Radiation Dermatitis
Bacterial Decolonization to Prevent Radiation Dermatitis
The purpose of this study is to determine whether bacterial decolonization of the nares and skin prior to treatment with radiotherapy (RT) for patients with cancers of the head and neck or breast, can prevent high-grade radiation…
- Trial name
- NCT03883828
- Testing
- Chlorhexidine gluconate solution, Mupirocin Ointment
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Montefiore Medical Center
Stress Disorders, Post-Traumatic, Affect
Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health
Posttraumatic stress disorder (PTSD) has devastating health consequences. Evidence-based PTSD interventions address the substantial burden of PTSD on the health of individuals and societies; however, several individuals receiving…
- Conditions
- Stress Disorders, Post-Traumatic, Affect, Memory
- Trial name
- NCT05523453
- Testing
- Processing of Positive Memories Technique (PPMT), Supportive Counseling (SC)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Texas, Denton, TX
Proximal Humeral Fractures
Comparison of Early and Late Therapy for Adults With Non-Operatively Treated Proximal Humerus Fractures
The purpose of the study is to compare two common ways of rehabilitating after proximal humerus fractures treated non-operatively.
- Trial name
- NCT00438633
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Massachusetts General Hospital