Clinical trials: Physical Restraints
- Condition Physical Restraints
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Insulin Resistance, Obesity
Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity
A combination of generally regarded as safe (GRAS) compounds named GLY-LOW, which included: alpha lipoic acid, pyridoxamine, nicotinamide, piperine and thiamine, were examined in pre-clinical experiments.
- Conditions
- Insulin Resistance, Obesity, Cardiovascular Diseases, Cognitive Impairment
- Trial name
- NCT06242535
- Testing
- GLY-LOW
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hoskinson Health and Wellness Clinic
Cardiovascular Disease, Diabetes
Diet and Activity Promotion Among Older Working Adults
The trial will test whether the Alive email-delivered health behavior program can improve subjects' physical activity, fruits and vegetables and saturated/trans fats and added sugars.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Aging
- Trial name
- ALIVE (NCT01233063)
- Testing
- Physical Activity and Diet Intervention via Alive2
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Berkeley Analytics, Inc.
Glucose Homeostasis
Comparison of the Effects of a 12-Week Consumption of Two Carbonated Beverages on Insulin Sensitivity
The purpose of this study is to determine whether consumption of carbonated drinks containing sweeteners affect insulin sensitivity.
- Trial name
- SEDULC (NCT02031497)
- Testing
- Drink with sweeteners, Drink without sweeteners
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute For European Expertise in Physiology
Pulmonary Disease, Chronic Obstructive
Effects of Tiotropium on Breathing Capacity and Exercise Limitation in Early Stages of Chronic Obstructive Pulmonary Disease
Optimal clinical management in early stages of COPD is not established. Tiotropium has been shown to improve exercise tolerance during (CWR) cycle ergometry with GOLD stage II to IV COPD, improvements in constant speed treadmill…
- Trial name
- NCT01072396
- Testing
- Tiotropium
- Where
- 15 sites in United States, Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Physical Activity, Blood Pressure
Simulated Passive Jogging & Jumping Devices & NO
Movement is important for overall health. Lack of movement has been shown to be associated with numerous diseases. This study will assess the validity and usefulness of two innovative low risk, non-invasive wellness devices, the…
- Trial name
- NCT03426774
- Testing
- Gentle Jogger, Gentle Jumper
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sackner Wellness Products LLC
Cardiac Disease
SHAPE:SeeingtheHeartwithAIPoweredEcho
Establish transthoracic echocardiogram (TTE) exams performed with Bay Labs EchoGPS guidance technology can be used in a primary care setting to accurately identify cardiac disease.
- Trial name
- SHAPE (NCT03705650)
- Testing
- Limited Echocardiogram
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sara Guttas
Overweight and Obesity
Web-based Weight Loss Intervention
Excess weight is a major risk factor underlying leading causes of death globally, including cardiovascular disease, type 2 diabetes, and some cancers.
- Trial name
- NCT03400696
- Testing
- Lower carbohydrate diet, Higher fiber diet, Physical activity focused
- Where
- 2 sites in United States
- Volunteers
- 63,656 people, healthy volunteers welcome
- Sponsor
- 23andMe, Inc.
Cancer Prevention
Step up to Health, Nigeria! Impact of 2022 World Cancer Day Walk on Health Behaviors Among Nigerians
Cancer awareness is a critical element of cancer prevention and control. Creating public awareness on risk factors, preventative strategies, and the importance of early screening is the foundation upon which a cancer control…
- Trial name
- NCT05239325
- Testing
- World Cancer Day Walk
- Where
- Nigeria
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- AshtaYoga, LLC
Physical Activity
Caminamos: A Smartphone App for Latinas to Connect With Walking Partners
Despite numerous interventions designed to increase physical activity, few are specifically tailored to Latinas, a population where higher rates of obesity, diabetes, and other chronic diseases are present.
- Trial name
- Caminemos (NCT03854916)
- Testing
- Caminemos Juntas App, World Walking App
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
PHYSIOLOGICAL PHENOMENA, Homeostasis
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
TRU-OMNIBODY is a prospective observational study designed to develop and independently validate a research-only whole-body digital twin.
- Conditions
- PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
- Trial name
- TRU-OMNIBODY (NCT07805044)
- Testing
- Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Blood Pressure, Hypertension
Validation Study of CART BP as a Wearable Cuffless Blood Pressure Monitor
This study aims to evaluate the accuracy of the CART BP, a medically approved ring-type blood pressure monitor, in comparison to the traditional auscultatory method using a dual-head stethoscope.
- Conditions
- Blood Pressure, Hypertension, Blood Pressure, High, Blood Pressure, Low
- Trial name
- NCT06513975
- Testing
- CART BP, sphygmomanometer
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sky Labs
Mild Cognitive Impairment, So Stated, Mild Dementia
Cognitive/Physical Computer-Game Blended Training With Personalized Brain Network Activation Technology for the Elderly
The study involves a novel Virtual Reality Interface that offers full-body immersion "Alterniity AR" and more specifically computer exercises blended with game activities.
- Conditions
- Mild Cognitive Impairment, So Stated, Mild Dementia, Healthy
- Trial name
- AlterniityAR (NCT02417558)
- Testing
- Alterniity Augmented Reality (AAR), VideoGrade
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- XtremeVRI AG
Sleep Quantity, Sleep Efficiency
Sleep, Physical Activity, and Dietary Habits Among High School Student-athletes and Non-athletes During an Academic Semester
Adolescent's poor sleep habits have been linked to adverse outcomes. Recent advances in activity tracking have provided researchers with cost-effective and non-invasive measurements of sleep in a free-living environment.
- Trial name
- NCT04997603
- Testing
- Accelerometer
- Where
- 4 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Healthy
Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% Under Conditions of Heat and Exercise
The objectives of this study are to evaluate the pharmacokinetic and adhesion performance of ZTlido (lidocaine topical system) 1.8% during physical exercise, application of heat, and under normal conditions.
- Trial name
- NCT04150536
- Testing
- Lidocaine topical system 1.8%
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.
Exercise, Health Behavior
Physical Activity Smartphone App for African American Men (FitBros) Ph II
Low physical activity levels contribute to African American men experiencing health disparities across a number of chronic diseases.
- Conditions
- Exercise, Health Behavior, Technology
- Trial name
- NCT05621044
- Testing
- FitBrothers smartphone active app, Nike Training Club
- Where
- 3 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Fitness
The Effect of a Combination of Orange- and Pomegranate Actives on Physical Fitness in Elderly People
The primary objective of this study is to determine the effect of daily supplementation of a combined orange- and pomegranate extract for a period of 4 weeks on physical fitness compared to placebo.
- Trial name
- NCT03781999
- Testing
- Actiful
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- BioActor
Muscle Injury
The Effects of PeptiStrong and Exercise to Enhance Muscle Strength in Young Subjects
A randomised, double-blind, placebo controlled study to evaluate the effect of PeptiStrong supplementation in conjunction with an exercise program to enhance muscle strength and endurance in young male and female subjects.
- Trial name
- NCT05946746
- Testing
- PeptiStrong
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Newborns
UK Baby Study Using a Baby Wash and Lotion Regimen
The skin of a newborn has a sensitive skin barrier relative to an older child and an adult. Newborn's skin, for example, is extremely vulnerable to damage by environmental agents such as harsh detergents, some topical oils, and…
- Trial name
- BOND (NCT03142984)
- Testing
- Cosmetic Products
- Where
- 2 sites in United Kingdom
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Ventilation Therapy; Complications
Diaphragmatic Mobility In Ventilated Assisted Patients
The study was a randomized controlled trial. A total of 24 patients who met the inclusion criteria were included in this study and randomly divided by sealed envelope method into Experimental and Control groups with 12 patients…
- Trial name
- NCT04733261
- Testing
- Diaphragmatic mobility, Chest Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aqua Medical Services (Pvt) Ltd