Clinical trials: Physical Trauma
Burns
Assessment of the Treatment of Severely Burned With Anabolic Agents on Clinical Outcomes, Recovery and Rehabilitation
The purpose of the program is to study and characterize the outcome of burn injury with particular attention to improving the rehabilitation of burn survivors, including children.
- Trial name
- NCT00675714
- Testing
- Stable Isotope Infusion Study, Collection of blood and tissues, Radiology testing: Dual-energy X-ray absorptiometry (DEXA), ultrasound, MRI
- Where
- United States
- Volunteers
- 1,126 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Traumatic Brain Injury
Mayo Clinic Traumatic Brain Injury Model System Center: The CONNECT Trial
Mayo Clinic has been funded by the National Institute on Disability Independent Living \& Rehabilitation Research (NIDILRR) as a Traumatic Brain Injury (TBI) Model System Center continuously since 1998.
- Trial name
- CONNECT (NCT02088099)
- Testing
- Complex clinical intervention, Treatment as usual
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Injuries
Cartilage Injury and Remodeling After ACL Rupture and Reconstruction: Functional Imaging and Biomarkers
The proposed study will establish novel relationships between intra-articular MSC recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors, and downstream…
- Trial name
- NCT04970706
- Testing
- ACL reconstruction
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Burns
Indocyanine Green (ICG) and SPY Imaging for Assessment of Burn Healing
Three patients were recruited for assessment of ICG fluorescence in burns.
- Trial name
- NCT02766244
- Testing
- ICG/SPY, Antibiotic Ointment
- Volunteers
- 3 people
- Sponsor
- Texas Tech University Health Sciences Center
Myelopathy Cervical, Cervical Spondylosis
Establishing the Validity and Reliability of a Dexterity Assessment Tool
Every year, thousands of Canadians are diagnosed with degenerative cervical myelopathy (DCM), a form of non-traumatic injury caused by spinal cord compression in the neck.
- Conditions
- Myelopathy Cervical, Cervical Spondylosis, Spinal Cord Compression
- Trial name
- NCT05910593
- Testing
- Dexterity Assessment Tool
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Lateral Epicondylitis (Tennis Elbow), Lateral Epicondylalgia
Effectiveness of Combined Super Inductive System (SIS) Therapy With Therapeutic Exercise and Health Education in Lateral Elbow Tendinopathy
Background Lateral epicondylalgia is the most common cause of lateral elbow pain and affects approximately 1% to 3% of the population.
- Conditions
- Lateral Epicondylitis (Tennis Elbow), Lateral Epicondylalgia, Lateral Elbow Tendinopathy
- Trial name
- SIS (NCT07495254)
- Testing
- Super Inductive System (SIS), therapeutic dose, Therapeutic Exercise Program, Health Education
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- University of Vic - Central University of Catalonia
Wounds and Injuries, Physical Activity
Swiss Army Physical Fitness Training
The purpose of this study is to determine whether the new sport concept of the Swiss Armed Forces influences the physical and psychological fitness of the recruits.
- Conditions
- Wounds and Injuries, Physical Activity, Mood (Psychological Function), Motivation
- Trial name
- SAFT (NCT02570295)
- Testing
- Swiss Army Physical Fitness Training
- Where
- Switzerland
- Volunteers
- 722 people
- Sponsor
- Swiss Federal Institute of Sport Magglingen
Soft Tissue Filler Complication, Surgical Flap Ischemia
Randomized Evaluation of Indocyanine Green Fluorescence Angiography-Guided Versus Standard Clinical Perfusion Assessment During Gluteal Permanent Synthetic Filler Removal
This randomized clinical trial will compare indocyanine green fluorescence angiography-guided assessment with standard clinical assessment of gluteal flap perfusion during removal of permanent synthetic fillers.
- Conditions
- Soft Tissue Filler Complication, Surgical Flap Ischemia, Tissue Necrosis
- Trial name
- NCT07808957
- Testing
- Indocyanine Green, Standard Clinical Perfusion Assessment
- Where
- Colombia
- Volunteers
- 300 people
- Sponsor
- Research Inc
Traumatic Brain Injury, Subarachnoid Hemorrhage
Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention
To show that the use of intravenous levetiracetam(LEV;Keppra)for seizure prevention in patients in the Neuroscience Intensive Care Unit will result in fewer side effects compared to the current standard of care anticonvulsant and…
- Trial name
- Keppra (NCT00618436)
- Testing
- Levetiracetam, Phenytoin
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Cincinnati
Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
In the last four years alone, residents of Puerto Rico have experienced a slew of natural disasters including Hurricane Maria in 2017, earthquakes in 2019 and 2020, the continued COVID-19 pandemic from 2020-2022, and most…
- Conditions
- Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder, Stress, Burn Out
- Trial name
- NCT05701111
- Testing
- Start with the Heart Students, Start with the Heart Teachers, Cue Centered Therapy Counselors
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 80,800 people, healthy volunteers welcome
- Sponsor
- Stanford University
Occupational Injuries, Occupational Exposure
The Effect of Intelligent Exercise and Ergonomic Recommendations on Surgeon Musculoskeletal Discomfort
The goal of this clinical trial is to investigate the effects of Intelligent Physical Exercise Training (IPET) and ergonomic recommendations on musculoskeletal pain among abdominal and pelvic surgeons.
- Trial name
- NCT06112106
- Testing
- Intelligent Physical Exercise Training (IPET)
- Where
- 7 sites in United States, Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acute Kidney Injury, Biomarkers
Combining Biomarkers and Electronic Risk Scores to Predict AKI in Hospitalized Patients
The study's objective is to evaluate the additive value of renal biomarkers (from blood and urine) for identifying individuals at high risk for severe acute kidney injury (AKI) above that of a novel natural language processing…
- Trial name
- NCT05988658
- Testing
- ESTOP - AKI 2.0
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Chicago
Spinal Cord Injuries, Respiratory Complication
Parameters Related to Physical Activity Level in SCI
Spinal cord injury (SCI) is a devastating health condition associated with permanent disability and reduced life expectancy. It is stated that its annual incidence worldwide varies between 12.1 and 57.8 per million, and its…
- Conditions
- Spinal Cord Injuries, Respiratory Complication, Cardiovascular Complication
- Trial name
- NCT06089226
- Testing
- Assessment Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istinye University
Fracture Femur, Hip Arthroplasty Replacement
Cognitive and Physical Recovery After Hip Fracture in Frail Patients Using Digital Rehabilitation Technology
The aim of this study is to evaluate whether integrating a technology-based rehabilitation approach with conventional therapies in the rehabilitation of patients with proximal femoral fracture may be advantageous compared with…
- Conditions
- Fracture Femur, Hip Arthroplasty Replacement, Total Hip Arthroplasty (THA)
- Trial name
- FEWF (NCT07392515)
- Testing
- Experimental intervention - integrated treatment with a sensor-based device, Conventional rehabilitation intervention
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- C.O.T. Cure Ortopediche Traumatologiche S.p.A.
Brain Injuries
Brain Injury Therapy of Exercise and Enriched Environment
The purpose of this study is to determine whether exercise or exercise with enrichment is beneficial in individuals who previously had a head injury.
- Trial name
- BITEEE (NCT03256643)
- Testing
- Exercise, Delayed Exercise, Exercise and enrichment
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Wayne State University
Craniocerebral Trauma
Fitness Training After Traumatic Brain Injury
The aim of this project is to compare the efficacy of two different fitness exercise programmes on improving fitness and psychosocial functioning in a traumatic brain injured population.
- Trial name
- NCT00251108
- Testing
- Cardiorespiratory fitness training
- Where
- 3 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Sydney South West Area Health Service
Bladder (Urothelial, Transitional Cell) Cancer, TURBT
INTRAOPERATIVE BLADDER INJURY ASSESSMENT IN TURBT USING BICEP
Transurethral resection of bladder tumor (TURBT) is the cornerstone procedure in the diagnosis and treatment of bladder cancer but is associated with a spectrum of intraoperative bladder injuries ranging from minor mucosal tears…
- Conditions
- Bladder (Urothelial, Transitional Cell) Cancer, TURBT, Bladder Injury
- Trial name
- BICEP in TURBT (NCT07396038)
- Testing
- No intervention is assigned as part of this observational study. All procedures are performed as part of routine clinical care.
- Volunteers
- 1,000 people
- Sponsor
- Necmettin Erbakan University
Closed Femur Fracture
Rehabilitation Enhanced by Partial Arterial Inflow Restrictions
The Rehabilitation Enhanced by Partial Arterial Inflow Restriction (REPAIR) Study will be conducted in a patient population of individuals recovering from a traumatic diaphyseal fracture of the femur.
- Trial name
- REPAIR (NCT02746458)
- Testing
- Blood Flow Restriction, Delfi PTSII Tourniquet System
- Where
- 8 sites in United States
- Volunteers
- 219 people
- Sponsor
- Major Extremity Trauma Research Consortium
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Postmenopausal Osteopenia
Effects of Kinect-based Virtual Reality Training in Postmenopausal Women With Osteopenia
Osteopenia is a clinical term to define the declined Bone Mineral Density (BMD) as per the normal reference values but not low enough to meet osteoporotic diagnostic criteria.
- Trial name
- NCT04862910
- Testing
- Kinect Based Virtual Reality Training, Control Group
- Where
- 2 sites in Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
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