Clinical trials: Physical Trauma
Acute Respiratory Distress Syndrome, Diaphragm Injury
Re-Evaluation of Systemic Early Neuromuscular Blockade and Transthoracic Ultrasound Assessment of the Diaphragm
ROSETTA is a multi-centre study evaluating the time course of diaphragm thickness and function following exposure to neuromuscular blockade or control in patients with acute respiratory distress.
- Conditions
- Acute Respiratory Distress Syndrome, Diaphragm Injury, Neuromuscular Blockade
- Trial name
- ROSETTA (NCT03132896)
- Where
- 6 sites in United States
- Sponsor
- University Health Network, Toronto
Scar Formation, Autologous Fat Grafting
3-D Imaging Assessment of Scar Formation and Would Healing in Fat Grafted vs Non-Fat Grafted Facial Reconstruction Wound Sites
The purpose of this study is to assess scar-formation and wound healing following the use of autologous fat grafting in facial reconstruction patients.
- Trial name
- NCT01750424
- Testing
- Autologous Fat Grafting, No intervention
- Where
- United States
- Sponsor
- Yale University
Carpal Tunnel Syndrome
Preoperative Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome
Study Design: A double-blind randomized controlled study. Background: Patients operated on for carpal tunnel release surgery may persist with pain after surgery, which could be modulated by psychosocial factors such as…
- Trial name
- NCT03576196
- Testing
- Preoperative Pain Neuroscience Education, Usual Care
- Where
- Chile
- Volunteers
- 2 people
- Sponsor
- Hospital Clínico La Florida
Rib Fractures, Pain
The Pain Control in Rib Fracture With Non-invasive Stabilization (RCT)
Brief summary: Background: Rib fractures are one of the most common causes of trauma disabilities and have become an important health issue. Patients usually suffer from severe pain.
- Conditions
- Rib Fractures, Pain, Thorax; Fracture
- Trial name
- NCT05080686
- Testing
- Posthorax Thoraxbelt
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Hip Injuries and Disorders
Investigating Postural Parameters in Different Hip Pathologies
"It is known that pelvic parameters affect physical hip functions in hip pathologies. Depending on the type and severity of hip pathologies, posture, muscle strength, balance, and pain parameters may change, thereby impacting an…
- Trial name
- NCT06851793
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ototoxicity, Unspecified Childhood Solid Tumor, Protocol Specific
Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin
RATIONALE: New ways to find out about hearing loss after treatment with chemotherapy may improve the ability to plan cancer treatment and may help patients live more comfortably.
- Trial name
- NCT00458887
- Testing
- management of therapy complications
- Where
- 81 sites in United States, Australia and 1 more
- Volunteers
- 301 people
- Sponsor
- Children's Oncology Group
Spinal Cord Injuries (SCI)
A Comprehensive Assessment of Altered Embodiment in Individuals With Spinal Cord Injury
Spinal cord injury (SCI) occurs when trauma or other factors damage the spinal cord, disrupting the flow of sensory information from the body to the brain.
- Trial name
- SCI_Embodiment (NCT06688916)
- Testing
- Behavioral assessment, Functional Magnetic Resonance Imaging (fMRI)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Proximal Femur Fractures, Nerve Block Assessment
Comparison Of Preoperative Ultrasound Guided Fascia Iliaca Block Versus Femoral Nerve Block for Proximal Femur Fractures Before Positioning for Spinal Anaesthesia
Proximal femur fractures are among the most painful orthopedic injuries Adequate analgesia is essential to facilitate positioning for spinal anesthesia, reduce opioid requirements, and minimize related complications.
- Trial name
- NCT07716358
- Testing
- Femoral Nerve Block, Fascia Iliaca Nerve Block
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Sahara Medical College Narowal Pakistan
ACL Injury, Meniscal Injuries
Intraoperative Energy Expenditure During ACL Reconstruction Surgery
This prospective observational study evaluates the intraoperative energy expenditure of the surgeon during anterior cruciate ligament reconstruction procedures.
- Trial name
- NCT07683247
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- ASL Lecce
Trauma-related Mental Health Symptoms
Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans
The current proposal aims to refine and examine an intervention called Calm Moms. Calm Moms is a web-based treatment program designed to reduce anxiety, stress, and low mood symptoms among pregnant Veterans with a history of…
- Trial name
- NCT06906185
- Testing
- Calm Moms-V, Care As Usual
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Osteoporosis Fracture
Continuation of Anti-osteoporotic Treatment 1 Year After Initial Administration
The aim of this observational study is to assess the obstacles and levers to the continuation of anti-osteoporotic treatment, and to identify those where action could be taken to improve the quality of care for fractured…
- Trial name
- POUROSTEO (NCT06024148)
- Testing
- phone survey
- Volunteers
- 250 people
- Sponsor
- University Hospital, Grenoble
Bone Fractures
Kefir Peptides for Bone Fracture Healing
This study is designed to evaluate the effects of kefir-derived peptides on bone healing in patients with upper limb fractures. Kefir peptides are natural protein fragments that may promote bone formation and reduce inflammation.
- Trial name
- KPs-Fracture (NCT07166458)
- Testing
- Kefir Peptide, Standard Care (in control arm)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Jen-Chieh Lai
Brain Injuries
Examination of Virtual Supermarket (Vmall) as an Assessment of Executive Functions in Children and Adolescents With Acquired Brain Injury
The purpose of this research is to find whether or not there are differences in the executive functions during "shopping" in a "virtual mall", between children with Acquired Brain Injury (ABI) vs healthy children.
- Trial name
- NCT00425958
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Holistic Care, Mental Health
Using Integrated Care and Wearable Technology to Evaluate Outcomes of the Shields & Stripes Program for Veterans and First Responders
This study aims to evaluate outcomes from the Shields \& Stripes (S\&S) program - a 12-week, multidisciplinary wellness intervention designed for veterans and first responders.
- Conditions
- Holistic Care, Mental Health, Sleep, PTSD
- Trial name
- S&S Wellness (NCT07452900)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor University
Complex Regional Pain Syndrome, Peripheral Nerve Injuries
Somatosensory Assessment and Rehabilitation of Allodynia (SARA)
This pilot study will test a new therapy, somatosensory rehabilitation, for the painful sensitivity experienced by persons with nerve injuries and/or complex regional pain syndrome (CRPS).
- Conditions
- Complex Regional Pain Syndrome, Peripheral Nerve Injuries, Hand Fractures
- Trial name
- SARA (NCT02070367)
- Testing
- Somatosensory rehabilitation, Usual treatment: physiotherapy
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Exercise, Developmental Dysplasia of the Hip
Physical Therapy Applications on the Hip and Defined Functional Parameters in Children With Developmental Hip Dysplasia
The aim of this study was to investigate the effects of physical therapy and rehabilitation applications on the hip and defined functional parameters in children with developmental hip dysplasia.
- Trial name
- NCT06007833
- Testing
- Physical Therapy and Rehabilitation Modalities, Conventional Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Inonu University
Chronic Liver Injury, Mindray Hepatus 9 Ultrasound Diagnostic System
Multicenter Clinical Study on Noninvasive Assessment of Hepatic Steatosis and Fibrosis Using Visual Transient Elastography
Using liver biopsy as the gold standard, this study will conduct visual transient elastography (ViTE) examinations using Mindray Hepatus 9 ultrasound diagnostic system in patients with liver injury to evaluate the diagnostic…
- Trial name
- NCT07128108
- Testing
- Visual Transient Elastography (ViTE) Examination
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Cognitive Dysfunction
Effects of Dexmedetomidine on Cognitive Outcome and Brain Injury Markers
Dexmedetomidine is a drug with sedative, anxiolytic, and analgesic properties. Benefits of its use covers good sedations without respiratory suppression, reduced circulating catecholamines due to decreased sympathetic…
- Trial name
- NCT03585452
- Testing
- Dexmedetomidine Infusion, Propofol based general anesthesia
- Where
- Poland
- Volunteers
- 23 people
- Sponsor
- Michał Kowalczyk
Spinal Cord Injuries
Effectiveness of NEUROM and tDCS for Motor Recovery in Chronic Paraplegia
Traumatic Spinal Cord Injury (TSCI) is a catastrophic, unexpected, and devastating event that can occur along the spinal column (cervical, thoracic, and lumbar).
- Trial name
- NEUROM (NCT04790149)
- Testing
- Conventional Rehabilitation, NEUROM + tDCS, NEUROM
- Where
- Lebanon
- Volunteers
- 56 people
- Sponsor
- Lebanese University
Anterior Cruciate Ligament Injury, Muscle Weakness
WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery
An assessment of the effect of surgical anterior cruciate ligament (ACL) on thigh muscles is critical to the improvement of knee rehabilitation and preservation.
- Trial name
- WEAKNESS (NCT03200678)
- Testing
- isokinetic assessment
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
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