Clinical trials: Physical Trauma
Prostatectomy, Neutrophil Gelatinase-Associated Lipocalin
Evaluation of Kidney Damage Using NGAL Measurements
The main objective of this study is to evaluate whether blood NGAL measurement provides superiority over sCr and BUN tests in early diagnosis for assessing renal function in patients undergoing robotic urological surgery.
- Conditions
- Prostatectomy, Neutrophil Gelatinase-Associated Lipocalin, Kidney Function Tests
- Trial name
- NCT06274125
- Testing
- Robotic-Assisted Laparoscopic Radical Prostatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara City Hospital Bilkent
Concussion, Brain, Motor Vehicle Accident
Research Evaluating Sports ConcUssion Events - Rapid Assessment of Concussion and Evidence for Return
RESCUE-RACER is jointly sponsored by the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. The RESCUE-RACER programme evaluates motorsports competitors at baseline (CArBON) and post-injury (CARS).
- Trial name
- RESCUE-RACER (NCT03844282)
- Testing
- Clinical assessment (SCAT5), ImPACT, CANTAB
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Spinal Cord Injuries
Experience of Rehabilitation Amongst Individuals With Paraplegia
This study is a qualitative study exploring the facilitators to physical and vocational rehabilitation and also explores the barriers in empowering individuals with paraplegia
- Trial name
- NCT05267223
- Testing
- Semi-structured interviews
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Asir John Samuel
Tennis Elbow, Health Adult Subjects
Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)
This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus.
- Conditions
- Tennis Elbow, Health Adult Subjects, Lateral Elbow Tendinopathy (Tennis Elbow), Pressure Pain Threshold (PPT)
- Trial name
- NCT07178288
- Testing
- Physiological/measurement-validation study
- Where
- Jordan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Lateral Epicondylitis (Tennis Elbow), Lateral Epicondylalgia
Effectiveness of Combined Super Inductive System (SIS) Therapy With Therapeutic Exercise and Health Education in Lateral Elbow Tendinopathy
Background Lateral epicondylalgia is the most common cause of lateral elbow pain and affects approximately 1% to 3% of the population.
- Conditions
- Lateral Epicondylitis (Tennis Elbow), Lateral Epicondylalgia, Lateral Elbow Tendinopathy
- Trial name
- SIS (NCT07495254)
- Testing
- Super Inductive System (SIS), therapeutic dose, Therapeutic Exercise Program, Health Education
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- University of Vic - Central University of Catalonia
Cirrhosis, Liver, Acute Kidney Injury
Initial Resuscitation for Acute Kidney Injury in Cirrhosis
The goal of this interventional study is to evaluate two strategies for how to provide intravenous (IV) fluids for treating patients with acute kidney injury (AKI) in cirrhosis.
- Conditions
- Cirrhosis, Liver, Acute Kidney Injury, Hepatorenal Syndrome
- Trial name
- RAKI-VAGA (NCT06525623)
- Testing
- Recommendation: No Further Resuscitation, Recommendation: Resuscitation with Crystalloid, Recommendation: Resuscitation with Colloid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Accident Injury, Home Injury
Implementation of the Child Housing Assessment for a Safe Environment
This implementation study uses a multi-method quantitative and qualitative, non-experimental design to estimate the magnitude of home injury risks, identify strategies for addressing those risks and sustaining those…
- Trial name
- CHASE (NCT05886270)
- Testing
- Housing Assessment/Safety Modifications
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post Traumatic Stress Disorder
Effects of Antagonistic Actions in Response to Trauma Exposure
The overarching objective of this study is to investigate the use of antagonistic actions as a treatment augmentation strategy for enhancing emotional processing during exposure to trauma-relevant stimuli.
- Trial name
- NCT04617769
- Testing
- Psychoeducation, Exposure
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Texas at Austin
Wound Infection Bacterial, Identification
Percutaneous Wound Sampling With Analysis in Blood Culture (PERKA-B) Method
The aim of this study was to evaluate whether there is a difference in pathogen detection rates when tissue samples obtained from infected wound sites are processed using standard microbiological methods compared with inoculation…
- Trial name
- NCT07325786
- Testing
- Tissue culture collection
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Prof. Dr. Bülent M. Ertuğrul
Cardiac Surgery, Brain Injury
The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS)
Context: Neurocognitive dysfunction complicates coronary artery bypass graft surgery. Neurocognitive dysfunction is a measurable problem with thinking. Erythropoietin may be a neuroprotectant.
- Trial name
- NCT00336466
- Testing
- Human recombinant erythropoietin
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Calgary
Acute Respiratory Failure With Hypoxia
PEEP in Patients With Acute Respiratory Failure
Positive end-expiratory pressure (PEEP) has become an essential component of the care of critically ill patients who require ventilatory support.
- Trial name
- NCT04912960
- Testing
- Mechanical ventilation
- Where
- 3 sites in Spain
- Volunteers
- 15 people
- Sponsor
- Jesus Villar
Acquired Brain Injury
Exercise and Physical Activity in Children With Pediatric Acquired Brain Injury
Exercise and physical activity in children with pediatric acquired brain injury
- Trial name
- DIScover_Ped (NCT06804486)
- Testing
- Exercise, Recommendation to Deprescribe
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidade da Coruña
Stress Disorders, Post-Traumatic
The Effects of Home-Based Telemental Health for Rural Veterans With PTSD
The intent of this study is to assess whether cognitive functioning improves as Post-Traumatic Stress Disorder (PTSD) symptoms decrease as a step toward developing an objective measure of PTSD improvement.
- Trial name
- HBTMH (NCT02295410)
- Testing
- CPT
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Pacific Islands Health Care System
Neuroinflammatory Response, Nerve Injury
Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity
The aim of this observational study is to answer the following questions in individuals with acute and chronic exposure to organophosphates. The main questions to be addressed are 1.
- Conditions
- Neuroinflammatory Response, Nerve Injury, Nerve Damage, Neurotoxicity
- Trial name
- NCT06021262
- Testing
- exposure to organophosphates
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Musculoskeletal Injury
Return to Baseball After BFR Therapy for Shoulder Injury
The literature is limited on whether BFR therapy provides improved return to function after acute rotator cuff or biceps rehabilitation in non-operative cases, and whether there is a clear mechanism of action in musculotendinous…
- Trial name
- NCT04248413
- Testing
- Blood Flow Restriction Therapy, Standard physical rehabilitation
- Sponsor
- Wake Forest University Health Sciences
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Burns (Physical Finding)
Mechanical Ventilation With and Without Postural Drainage in Burn Patients With ARDS
Inhalation injury become a more common cause of death in burn patients but alone the smoke injury has low mortality rate. It is reported that a combination of smoke injury with cutaneous burn increases the mortality rate and…
- Trial name
- NCT05321888
- Testing
- Mechanical Ventilation, Mechanical Ventilation with Postural drainage
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Postoperative Complications
Integrating Data, Algorithms and Clinical Reasoning for Surgical Risk Assessment
Brief Summary: The goal of this study is to implement and test an intelligent perioperative system (IPS) that in real-time predicts risk for postoperative complications using routine clinical data collected in electronic health…
- Trial name
- IDEALIST (NCT02741986)
- Testing
- Risk estimation
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Florida
Fractures, Bone, Patient Fall
Bone Strength and Physical Activity in Patients With a Recent Clinical Fracture
The risk for a subsequent fracture is significantly higher in patients presenting with a fracture compared to individuals without a previous fracture and is highest within the first 2 years after the initial fracture.
- Conditions
- Fractures, Bone, Patient Fall, Osteoporosis, Physical Activity
- Trial name
- NCT05138640
- Testing
- Not applicable. The study is designed as an observational cohort study
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Joop P.W. van den Bergh
Psychiatric Disorder, Stress Reaction
Real-Time Assessment of Stress and Stress Response
Stress is a complex natural phenomenon, frequently related to a physiological response, including heart rate, heart rate variability, respiratory rate, skin conductance and temperature.
- Conditions
- Psychiatric Disorder, Stress Reaction, Stress, Psychological, Stress, Physiological
- Trial name
- NCT04100213
- Testing
- Trier Social Stress Test
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
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