Clinical trials: Physiological Measurement
Heartburn, Gastro-esophageal Reflux
Assessment of Gastro-esophageal Reflux Using Endo-Flip vs Bravo
Monitoring oesophageal pH provides a definitive diagnosis of patients with gastro-oesophageal reflux disease (GORD), especially those in whom the association between reflux and symptoms is uncertain and those under consideration…
- Trial name
- NCT00481949
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Erectile Dysfunction
TRIP-patch vs Duplex
To measure saturation and desaturation of the cavernosal tissue with a cutaneous placed penile sensor, before and during full rigidity.
- Trial name
- NCT06402097
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- St. Antonius Hospital
Respiratory Rate Monitoring
Validation of Respiratory Rate Measurement Accuracy Using a Smartwatch
This prospective study evaluates the accuracy of commercial wearable devices by comparing their respiratory rate measurements against clinical standards like spirometers and ECGs in healthy adults.
- Trial name
- BREATHWATCH (NCT07578389)
- Testing
- Respiratory rate monitoring using wearable device
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Erectile Dysfunction
Feeling Hot 1: Environmental Influences of Overnight Measurement on Skin Temperature of the Erectile Penis
The Feeling Hot studies focus on the proof-of-principle of using temperature sensing as a tool to detect nocturnal erections. In the Feeling Hot 1 study the influence of environmental factors of overnight measurements are studied…
- Trial name
- NCT05183581
- Testing
- Feeling Hot sensor system
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Using Remote Photoplethysmography for Physiological Parameters
Evaluation of Remote Photoplethysmography to Assist Vital Signs Measure in Pediatrics
Introduced in 1930, photoplethysmography techniques presented the possibility of measuring SpO2 and heart rates (HR) using the absorption of light by the blood to define these signals.
- Trial name
- rMonitoped1 (NCT06231654)
- Testing
- Remote photoplethysmography for physiological parameters
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Fondation Lenval
Healthy
Chiropractic Adjustment on Physiological Measurements
This research is designed to study the effects of chiropractic adjustment on the physiological responses (EEG, EMG, HRV, skin temperature, and respiration) of college student and faculty population.
- Trial name
- NCT00379873
- Testing
- ProAdjuster
- Volunteers
- healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Physiological Responses to Contact With Dogs, Psychological Responses to Contact With Dogs
Measuring Effects of Contact to Dogs
The study aims to identify and quantify objective non-invasive measures of the immediate effect of contact with dogs in a standardized experimental setup.
- Conditions
- Physiological Responses to Contact With Dogs, Psychological Responses to Contact With Dogs, Behavioural Responses to Contact With Dogs
- Trial name
- NCT04696419
- Testing
- Different intensities of contact to dogs
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Vulvovaginal Atrophy, Genital Disorder
Psychometric Validation of the Portuguese DIVAS-Q in Women With Vulvovaginal Atrophic Symptoms
To determine the reliability and validity of the Portuguese version of the DIVA questionnaire in Portuguese women. This validation will support its use both in research and in routine clinical practice in this population.
- Conditions
- Vulvovaginal Atrophy, Genital Disorder, PROMs
- Trial name
- DIVAS-Q (NCT07250490)
- Where
- Portugal
- Volunteers
- 300 people
- Sponsor
- Instituto Politécnico de Leiria
Psychological Stress, Heart Rate Variability
A Database for Emotion Analysis Using Physiological and Psychological Assessment by 40FY
A comprehensive study examining the physiological, emotional and psychological aspects of stress among Korean adults
- Conditions
- Psychological Stress, Heart Rate Variability, Mental Health Services
- Trial name
- NCT06172673
- Where
- South Korea
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- 40FY
Pelvic Floor Disorders, Sexual Dysfunction
A Multi Center Study to Validate a Condition-specific Measure of Sexual Health in Women With Pelvic Floor Disorders
Study Aims: 1. To validate a new measure of sexual function and activity in women with PFDs; 2. To establish the responsiveness to change of the new measure.
- Conditions
- Pelvic Floor Disorders, Sexual Dysfunction, Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT00952406
- Testing
- Survey
- Where
- 14 sites in United States, United Kingdom
- Volunteers
- 877 people
- Sponsor
- International Urogynecological Society
Respiratory; Disorder, Functional, Impaired
Evaluation of the Metrological Reliability of Connected Objects in the Measurement of Medical Physiological Parameters
Many connected objects available over-the-counter to the general public claim to measure physical quantities that may have a medical application.
- Trial name
- EVALEXPLO (NCT03803098)
- Testing
- reference measure, alternative measure
- Where
- 2 sites in France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Physiological Responses, Behavior
Behavioural and Physiological Responses to Dog Visits in Nursing Homes
In brief the study aims to investigate how nursing home residents receiving dog visits respond to contact with the dog, by comparing visits with and without a dog present.
- Conditions
- Physiological Responses, Behavior, Mood
- Trial name
- NCT05516264
- Testing
- Dog visits/control visits, Control visits/dog visits
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acute Respiratory Failure, High Flow Nasal Cannula
Tracheal Positive Pressure During High Flow Nasal Oxygen Administration in Critically Ill Patients: a Physiologic Study.
High flow nasal cannula administration in critically ill patients is frequently used to improve acute respiratory failure or to prevent respiratory failure after extubation.
- Conditions
- Acute Respiratory Failure, High Flow Nasal Cannula, Critically Ill, Airway Disease
- Trial name
- HPEEP (NCT05467332)
- Testing
- HIGH FLOW NASAL OXYGEN
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Sleep Apnea
Validation of a Contactless Vital Signs Measurement Sensor
The primary aim of this study is to validate the performance of Sleepiz One+ for the measurement of vital physiological parameters in adult population, against a laboratory-based polysomnography.
- Trial name
- NCT04676191
- Testing
- Sleepiz One+, Polysomnography
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- Sleepiz AG
Skin Thickness
Echographic Measurement of Skin Thickness in Children
To optimize a medical device for intradermal injection, knowledge concerning the thickness of epidermis and dermis at the proximal forearm is required.
- Trial name
- PIDIC-1 (NCT02727114)
- Testing
- Echographic measurement of skin thickness
- Where
- 3 sites in Belgium
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Novosanis NV
Urologic Diseases, Patient Satisfaction
Developing a PROM for Recurrent Urinary Tract Infection
This study aims to develop and validate the first set of patient-reported outcome measures for recurrent urinary tract infection (UTI): the Recurrent UTI Symptom Scale and the Recurrent UTI Impact Questionnaire.
- Conditions
- Urologic Diseases, Patient Satisfaction, Pain, Chronic, Sexual Dysfunction
- Trial name
- NCT05086900
- Testing
- Non-interventional Cross-sectional Patient Reported Outcome Measure Development
- Where
- United Kingdom
- Volunteers
- 283 people
- Sponsor
- University of Reading
Respiration Rate, Monitoring, Physiologic
Respiratory Rate Validation Study
The goal of this clinical trial is to test how accurately a new chest-worn device called the Perin Health Patch measures breathing rate in adults aged 22 and older.
- Trial name
- NCT07147907
- Testing
- Chest Worn Respiratory Rate Monitor
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Perin Health Devices
Critical Illness
Cortisol Levels as a Measure of Accumulated Physiological Stress in ICU Patients Undergoing Mechanical Ventilation
Critical illness is a situation of severe and prolonged stress for patients with mechanical ventilation (MV). Between 40-80% of these patients present the Post-ICU syndrome, a set of physical, cognitive, psychological alterations…
- Trial name
- Corti-COG (NCT03736135)
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Corporacion Parc Tauli
Cardiovascular Physiological Phenomena, Intensive Care Unit Syndrome
Echocardiographic Measurement of Myocardial Work
Echocardiography is recommended for the hemodynamic management of patients with shock. Recently, a new echocardiographic method has been proposed that provides a non-invasive measurement of myocardial work incorporating different…
- Trial name
- MYOLOAD (NCT06422481)
- Testing
- Fluid administration, Norepinephrine administration or increase in norepinephrine dosage
- Where
- 3 sites in France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
MRI, Sequence Optimization
Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects
IRMaGe is a Joint Service Unit (UMS) which provides users of brain exploration equipment (clinical MRI and preclinical, TMS, EEG, NIRS and metabolomics).
- Conditions
- MRI, Sequence Optimization, Physiological Measurement
- Trial name
- MAP-IRMaGE (NCT05036629)
- Testing
- MRI Protocol
- Where
- France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble