Clinical trials: Physiopathology
Stroke, Shoulder Dislocation or Subluxation
Effect of High Intensity Laser on Hemiplegic Shoulder Dysfunction
Hemiplegic shoulder pain (HSP) is a common and disabling complication following a stroke, and it may affect the quality of life. It often occurs following two to three months of stroke.
- Trial name
- NCT05595720
- Testing
- hight intenisty laser
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Deraya University
Constipation, Constipation - Functional
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle…
- Conditions
- Constipation, Constipation - Functional, Dyssynergia
- Trial name
- NCT05823259
- Testing
- Hybrid Telehealth Program: Respiratory Muscle Training and Patient Education, Standard Physical Therapy Care
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Inflammation, Cognitive Impairment
Trial Assessing Light Intensity Exercise on the Health of Older Breast Cancer Survivors
The Trial Assessing Light-Intensity Exercise on the Health of Older Breast Cancer Survivors pilot randomized controlled trial aims to evaluate the efficacy of a home-based, light-intensity physical activity intervention among 56…
- Conditions
- Inflammation, Cognitive Impairment, Anxiety, Alcohol Drinking
- Trial name
- TALIEHO (NCT04965246)
- Testing
- Physical Activity, Usual Care
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Milton S. Hershey Medical Center
Cognitive Impairment
Health Care Courses of Elderly Hospitalized Patients for Inappropriate Reasons: Qualitative and Economic Analyzes
For almost 17 % of cases patients over 75 years are sent for inappropriate reasons to the emergency unit. They are described as inappropriate hospitalization because they don't require the use of technical platform or diagnostic…
- Trial name
- PAGE (NCT02749669)
- Testing
- Qualitative research
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Régis AUBRY
Erectile Dysfunction Following Radical Prostatectomy
Safety and Tolerability of a Novel Implantable Device for the Treatment of Erectile Dysfunction
The goal of this clinical trial is to assess if a new device is safe to use as a potential treatment for erectile dysfunction following radical prostatectomy.
- Trial name
- NCT06968494
- Testing
- Activation of pro-erectile nerves within the pelvic plexus
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Comphya Inc.
Mild Cognitive Impairment (MCI)
Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients
The goal of this study is to evaluate the safety and tolerability of Gamma Glutamylcysteine (GGC) supplement at different doses (400mg/day or 800mg/day or 1200mg/day) when administered orally to patients with MCI over 3 months.
- Trial name
- MCI-GSH (NCT07583251)
- Testing
- Gamma- Glutamylcysteine, Gamma- Glutamylcusteine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Pravat Mandal
Parkinson Disease
Investigating the Cholinergic Contribution to Gait Dysfunction in Parkinson's Disease
People with Parkinson's disease often experience problems with 'gait' and balance. Gait refers to the way a person moves while walking, such as their speed and length of steps.
- Trial name
- NCT06903910
- Testing
- Donepezil (Aricept)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Virginia
Temporomandibular Joint Disorders, Temporomandibular Joint Pain
Intra-articular I-PRF Injections in Patients With Temporomandibular Joint Dysfunction
The aim of the study will be to analyze the results of injection treatment in patients diagnosed with temporomandibular joint dysfunction manifested by pain and/or limited jaw mobility.
- Trial name
- NCT05883982
- Testing
- I-PRF injection
- Where
- Poland
- Volunteers
- 51 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
HIV, Endothelial Dysfunction
Safety and Efficacy of Salsalate to Treat Endothelial Dysfunction in HIV-infected Adults
This is a phase II, open label, randomized-controlled pilot study designed to study both the efficacy and safety of salsalate in decreasing endothelial cell dysfunction, systemic inflammation, and insulin resistance in…
- Conditions
- HIV, Endothelial Dysfunction, Inflammation, Insulin Resistance
- Trial name
- Salsalate (NCT01046682)
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University Hospitals Cleveland Medical Center
Heart Failure
QUantum Genomics Incremental Dosing in Heart Failure - QUID-HF
Heart Failure (HF) a common clinical condition characterized by either by a heart that does not pump sufficiently or becomes stiff. A variety of mechanisms contribute to progressive cardiac remodeling and dysfunction.
- Trial name
- QUID-HF (NCT02780180)
- Testing
- QGC001
- Where
- 23 sites in Czechia, France and 6 more
- Volunteers
- 23 people
- Sponsor
- Quantum Genomics SA
Mild Cognitive Impairment (MCI)
Evaluation of the Effect of Healthy Lifestyle Intervention for Patients With Mild Cognitive Impairment
This clinical study aims to evaluate the feasibility and preliminary effectiveness of a comprehensive lifestyle intervention program for patients with mild cognitive impairment.
- Trial name
- NCT06942780
- Testing
- Exercise intervention, Social intervention, Dietary intervention
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Pelvic Floor Disorders
Pelvic Floor Dysfunction Among Female Physiotherapy Students: A Cross-Sectional Study
This study aims to: 1. estimate the prevalence of pelvic floor dysfunction among female physiotherapy students at Cairo University. 2.
- Trial name
- NCT06808542
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Cairo University
Environmental Enteric Dysfunction
Glucagon-like Peptide 2 (GLP-2) in Undernourished Women Improving From Histology-Confirmed Environmental Enteric Dysfunction (EED)
The goal of this clinical trial is to learn whether teduglutide, a medicine that helps the intestine heal, can improve environmental enteric dysfunction in undernourished women aged 18 to 35 years living in urban slums of Dhaka.
- Trial name
- GAME (NCT07537686)
- Testing
- Teduglutide 0.05 dose
- Volunteers
- 55 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Erectile Dysfunction
Endovascular Therapy for Erectile Dysfunction
Brief Summary: Background and pathophysiology Erectile dysfunction is a serious disease with a significant impact on the quality of life.
- Trial name
- RE-ACTION (NCT04333173)
- Testing
- endovascular procedure
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Clinica San Gaudenzio
Cognitive Decline, Cognitive Impairment, Mild
Evaluation of Pilot Community-based Multi-domain Program Older Adults at Risk of Cognitive Impairment
The multi-domain programme was adapted from a larger international multi-domain interventional study for the Singapore community of older adults at risk of cognitive impairment.
- Trial name
- NCT04440969
- Testing
- Multi-domain intervention
- Where
- Singapore
- Volunteers
- 199 people
- Sponsor
- Geriatric Education and Research Institute
Lung Transplant Infection
Inhaled Beclomethasone After Community-Acquired Respiratory Viral Infection in Lung Transplant Recipients
The purpose of this study is to determine if the use of inhaled beclomethasone after a community-acquired respiratory viral infection in a lung transplant recipient decreases the risk of the subsequent development of chronic lung…
- Trial name
- NCT02351180
- Testing
- Inhaled beclomethasone
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Washington University School of Medicine
Multiple Sclerosis, Cognitive Deficits
Effects of Cognitive Behavioural Therapy and Exercise on Stress and Cognitive Deficits in Multiple Sclerosis
High levels of psychological stress have been reported by 90% of patients with MS experiencing disease exacerbation, and approximately 39% of those with more stable disease course.
- Conditions
- Multiple Sclerosis, Cognitive Deficits, Stress, Psychological
- Trial name
- NCT01763983
- Testing
- Cognitive Behavioural Therapy, Aerobic Exercise
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- Sunnybrook Health Sciences Centre
Alzheimer Disease, Mild Cognitive Impairment
Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease
This study investigates the effects of Valaciclovir treatment to individuals with Alzheimer's disease or Mild Cognitive Impairment of Alzheimer's Disease Type.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Herpes Simplex
- Trial name
- VALZ-Pilot (NCT02997982)
- Testing
- Valaciclovir 500Mg Tablet
- Where
- 2 sites in Sweden
- Volunteers
- 33 people
- Sponsor
- Hugo Lovheim
Adolescent Mental Health, Psychosocial Adaptation
Trauma-Informed School Intervention for Adolescent Mental Health and Self-Injury Prevention in China
This study evaluated a school-based psychosocial adaptive capacity enhancement program for Chinese adolescents. The program was developed to support students who may have experienced childhood household dysfunction or other…
- Conditions
- Adolescent Mental Health, Psychosocial Adaptation, Childhood Household Dysfunction
- Trial name
- TISI-China (NCT07583524)
- Testing
- School-Based Psychosocial Adaptive Capacity Enhancement Program
- Where
- China
- Volunteers
- 5,787 people, healthy volunteers welcome
- Sponsor
- WU Han
Cognitive Impairment, Cardiovascular Risk Factor
The Active Mind Study
The purpose of this study is to explore whether physical exercise, mindfulness training, or both interventions together can improve cognitive function in individuals with multiple risk factors for the development of dementia in…
- Trial name
- NCT03289546
- Testing
- Mindfulness training, Aerobic training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- The Miriam Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.