Clinical trials: Pigment; Lesion
Pigmentation
Evaluation of the Efficacy and Safety of PiQo4 System for the Treatment of Pigmented Lesions
A total of at least 25 healthy subjects at a single site, aged 21-70 years old with congenital or acquired challenging/resistant, age/sun-related flat and benign facial pigmentation with or without hand pigmentation who wish to…
- Trial name
- NCT03565146
- Testing
- PiQo4 Laser System
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Focus Medical, LLC
Cutaneous Mastocytosis
Improvement of Pigmented Skin Lesions in Patients With Mastocytosis After Performing 2 Sessions of Pigment Laser
Cutaneous mastocytosis can be isolated or associated with systemic involvement. Urticaria pigmentosa affects around 80 to 85% of adult patients with cutaneous mastocytosis.
- Trial name
- LaserMasto (NCT04377828)
- Testing
- Pigment laser
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Toulouse
Benign Pigmented Lesions
Pilot Evaluation of the Lutronic PicoPlus System for the Treatment of Benign Pigmented Lesions of the Hands
Prospective, multi-site, non-randomized study of up to 40 treated subjects; subjects enrolled may be greater than subjects treated.
- Trial name
- NCT04208100
- Testing
- PicoPlus
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Benign Pigmented Lesions
Evaluation of Laser Treatment for Benign Pigmented Lesions by Non-invasive, Cellular Resolution Optical Coherence Tomography
In recent years, with the maturity of laser technology, laser therapy is one of the popular options for the treatment of pigment diseases. The absorption spectrum of melanin ranges from 300 to 1,000 nm.
- Trial name
- NCT04861246
- Testing
- Laser, ApolloVue® S100 Image System, VISIA®
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Basal Cell Carcinoma, Melanoma
Multi-Wavelength and Coherence Confocal Reflectance Microscopy of Pigmented and Non-Pigmented Lesions on the Skin In-Vivo
The purpose of this study is to image skin and skin lesions with a new imaging technology called "multiwavelength and coherence confocal reflectance microscopy".
- Conditions
- Basal Cell Carcinoma, Melanoma, Non-Malignant Skin Disorders, Squamous Cell Carcinoma
- Trial name
- NCT00574392
- Testing
- Multiwavelength and coherence confocal reflectance microscopy (Vivascope 1500m multiwavelength)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Genital Tumor, Pigmented Lesions
Comparison of Dermatoscopy X400 Interpreted by 6 Non-dermatologists and an Artificial Intelligence Software Skin Artificial Intelligence Versus Dermatoscopy x 20
Pigmented lesions of the genital mucosa are common, affecting between 10% and 20% of the population. The clinical appearance is sometimes confusing.
- Trial name
- NCT06079619
- Testing
- Analysis of photos of pigmented tumours by the three groups
- Where
- France
- Volunteers
- 157 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pigmentation
Evaluation of Broadband Light Treatment Protocol for Pigmented Skin Lesions - A Comparative Study
Evaluation of Broadband Light Treatment Protocols for Pigmented Skin Lesions - A comparative study
- Trial name
- NCT05662592
- Testing
- Broadband Light
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Sciton
Acne, Acne Scars - Mixed Atrophic and Hypertrophic
AVAVA MIRIA General Use
A general protocol to treat a variety of dermatologic conditions and collect patient feedback. Primary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment.
- Conditions
- Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle
- Trial name
- NCT06868615
- Testing
- AVAVA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Skin Cancer
Spectral Diagnosis of Cutaneous Malignancy
The goal of this clinical research study is to evaluate the use of an imaging technology called spectral diagnosis. Researchers want to find out if a special spectral-diagnosis probe can be used to detect skin cancers.
- Trial name
- NCT00476905
- Testing
- Spectral Diagnosis Probe
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- M.D. Anderson Cancer Center
Wrinkle, Acne Scars
Post Market Usability Evaluation Of The PicoSure Pro Device
The intended use of the PicoSure and PicoSure Pro devices used in this study is to treat additional patients with the new PicoSure Pro device and collect additional data on the devices.
- Conditions
- Wrinkle, Acne Scars, Benign Epidermal Pigmented Lesions, Benign Dermal Pigmented Lesions
- Trial name
- NCT05102617
- Testing
- PicoSure Pro Device, PicoSure Device, Topical Cosmeceuticals
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Cynosure, Inc.
Wrinkle, Pigmented Lesions
Clinical Evaluation to Demonstrate the Safety and Performance of the Candela PicoWay System™
This study is intended to demonstrate the safety and efficacy of the PicoWay™ Laser System for its intended uses: clearance of benign pigmented lesions and improvement in appearance of wrinkles.
- Trial name
- NCT04727099
- Testing
- PicoWay Laser System
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Vascular Lesion, Pigmented Lesions
Safety and Efficacy Evaluation of SMART Camera Treatment Presets for Cutaneous Lesions Using IPL
Multi-center, Prospective, Open-Label with Before-After Study Design. Each subject will receive a single treatment. Treatment presets will be determined by the SMART Camera system and approved by the physician.
- Trial name
- NCT05755139
- Testing
- IPL with smart diagnostic handpiece
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Melanoma, Pigmented Lesions
Dermoscopy Augmented Histology Trial, a Randomized Controlled Trial
Pathologists provide the current gold standard in skin lesion diagnostics, most often primarily based on the interpretation of histological slides.
- Trial name
- DAHT-RCT (NCT05004792)
- Testing
- DermLoop Learn
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Benign Pigmented Lesions
Picosecond Laser for Ttreatment of Benign Pigmented Lesions
The purpose of this study is to determine whether Pico laser is effective and safe in the treatment of benign pigmented lesions.
- Trial name
- NCT02146820
- Testing
- GentleMax system
- Where
- 2 sites in United States, China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Actinic Keratosis
Development and Validation of a Quality of Life Instrument for Actinic Keratosis
Actinic keratoses (AKs) are some of the most common lesions seen by dermatologists. Flesh colored to erythematous, these lesions often present with scaling or crusting in sun damaged regions of the body.
- Trial name
- AKRQ (NCT01444989)
- Testing
- AKRQ questionnaire, Skindex-16, DLQI, Skin Health Calculator
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Benign Pigmented Lesions
785nm Picosecond Laser for Treatment of Benign Pigmented Lesions
This is an open-label, multi-center study. Subjects in this study will receive up to eight (8) treatments in 11±5 weeks (6-16 weeks) interval, with the PicoWay device using the 785 nm wavelength alone or combined with 1064 nm or…
- Trial name
- NCT02891239
- Testing
- PicoWay
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Lentigo, Hyperpigmentation
Efficacy and Tolerance of D-pigment Versus Moisturizer in Hands' Lentigo Lesions With or Without Laser Therapy
Pierre Fabre Dermo-Cosmétique has commercialized a cosmetic product (D-pigment rich texture) for treatment of hyperpigmentation.
- Trial name
- NCT03457246
- Testing
- D-Pigment rich texture, Hydrance optimale riche
- Volunteers
- 40 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Lesion; Pigment, Diagnostic Self Evaluation
Perceptual Expertise Training for Triage of Moles
The aim of this study is to assess a novel educational mobile and online application which will use images of pigmented skin lesions with question prompts to train future medical providers to more accurately detect malignant…
- Trial name
- NCT03246633
- Testing
- Perceptual Training
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Melanoma (Skin), Pigmented Lesions
Dermoscopy Augmented Histology Trial, Consensus Agreement Diagnosis Made by Dermatopathology Experts
It has been suggested that pathologists' diagnostic accuracy and confidence could be improved if they gained access to additional clinical information and in-vivo clinical and dermoscopic images of melanocytic tumors.
- Trial name
- NCT05712551
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Herlev Hospital
Epidermal Pigmented Lesions, Skin Toning
Evaluation of the 755nm Alexandrite Laser for Skin Toning and Epidermal Pigmented Lesions in Asian Skin Types
The purpose of this study is to assess treatment for facial skin toning and removal of epidermal pigmented lesions for Asian patients using the 755nm Alexandrite laser
- Trial name
- NCT01754246
- Testing
- 755nm Alexandrite Laser
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.