Clinical trials: Pilon Fractures, open to volunteers
Ankle Fractures, Pilon Fracture
Simplified Post Op Rehabilitation for Ankle and Pilon Fractures
The aim of this study is to compare standard post operative rehabilitation with a simplified wooden block stretching protocol that will yield similar results.
- Trial name
- NCT05280639
- Testing
- Wooden block, Formal physical therapy or Home Exercise Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Open Pilon Fractures
Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass
Open pilon fractures are challenging problems to manage. Infection rates vary from 6-30% and metaphyseal nonunion varies from 7-20%.
- Trial name
- NCT07227493
- Testing
- Fibergraft Aeridyan Matrix
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Missouri-Columbia
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Pilon Fractures
Talar Osteochondral Lesions With Pilon Fractures
Patients with pilon fractures have a high incidence of talar osteochondral lesions. In this study, patients will undergo ankle arthroscopy at the time of external fixation.
- Trial name
- NCT07553221
- Testing
- Diagnostic Ankle Nano-Arthroscopy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Missouri-Columbia
Pilon Fracture
Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)
High energy intra-articular fractures of the distal tibia, or Pilon fracture, is a devastating injury with multiple short and long term complications.
- Trial name
- NCT03652753
- Testing
- N-acetylcysteine, Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Missouri-Columbia
Ankle Fractures, Pilon Fracture
FRAME Study (Frailty-Related Ankle Fracture Management and Evaluation)
This will be a multi-centre randomized controlled trial, with London Health Sciences Centre (LHSC) as the lead site. Elderly patients with complex ankle fractures who meet the inclusion criteria and provide consent will be…
- Trial name
- FRAME (NCT05131321)
- Testing
- Primary ankle arthrodesis (fusion), ORIF (open reduction and internal fixation), Intramedullary Fibular Nailing (IMFN)
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Feasibility Study on Nitropaste Using Intraoperative SPY Imaging.
- Conditions
- Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)
- Trial name
- SPY NITROPASTE (NCT07004764)
- Testing
- Nitroglycerin Ointment 2%
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University