Clinical trials: Pilonidal Disease
Pilonidal Sinus, Wound Healing
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
This is a single-blinded, multicentre, prospective randomised controlled trial (RCT) comparing post-operative and patient-reported outcomes for patients undergoing application of negative-pressure wound therapy (NPWT) after sinus…
- Trial name
- ENVELOP (NCT06647290)
- Testing
- Negative Pressure Wound Therapy, Standard wound care
- Where
- 10 sites in Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
Pilonidal Sinus
Umblical Pilonidal Sinus Evaluation
Purpose: Pilonidal sinus disease (PSD) is a chronic inflammatory condition of skin due to implanted loose hair. PSD is commonly seen in sacrococcygeal region, but can also be seen in axilla, perineum, suprapubic regions, on hands…
- Trial name
- NCT04856605
- Testing
- surgery
- Volunteers
- 82 people
- Sponsor
- Istanbul Medeniyet University
Pilonidal Sinus of Natal Cleft, Pilonidal Sinus Without Abscess
Crystallized Phenol Treatment in Pilonidal Sinus
Pilonidal sinus disease is an acquired disorder of the natal cleft and its incidence is reported as 6 in 100,000. Although there are many opinions regarding the treatment of pilonidal sinus disease in the literature, surgery is…
- Trial name
- NCT04681443
- Testing
- Crystallized phenol application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gulhane Training and Research Hospital
Pilonidal Sinus
The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease
The use of local liquid phenol for pilonidal sinus disease was first introduced by Maurica and Greenwood in 1964. Phenol, also known as carbolic acid, has been proven to be an effective sclerosing agent for treating pilonidal…
- Trial name
- NCT06324656
- Testing
- crystallized phenol + platelet rich plasma application, crystallized phenol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Necmi Kadıoğlu Hospital
Pilonidal Disease
Surgical Approach for Pilonidal Disease
In our hospital, between January 2013 and January 2017, those operated with the Modified Limberg flap method after the Rhomboid excision due to pilonidal disease, and those operated with the un-roofing curettage method will be…
- Trial name
- NCT04334681
- Testing
- Un-roofing curettage method, Modified Limberg Flap Group
- Where
- Turkey (Türkiye)
- Volunteers
- 278 people
- Sponsor
- Konya Meram State Hospital
Squamous Cell Carcinoma, Pilonidal; Cyst, Malignant
Surgery Plus Intraoperative Radiotherapy as Treatment for Squamous Cell Carcinoma Over Pilonidal Disease.
Background: Pilonidal sinus is a very common disease. Malignant transformation occurs in 0,1% of patients. The investigators present a case of squamous cell carcinoma arised from recurrent pilonidal disease, managed by multimodal…
- Conditions
- Squamous Cell Carcinoma, Pilonidal; Cyst, Malignant, Surgery
- Trial name
- NCT04201002
- Testing
- Resection plus intraoperative radiotherapy
- Where
- 2 sites in Spain
- Volunteers
- 1 people
- Sponsor
- Hospital Provincial de Castellon
Pilonidal Sinus Disease, Sacrococcygeal Pilonidal Sinus
Primary Closure vs Open Technique for Pilonidal Sinus
The purpose of this randomized controlled trial is to compare two commonly used surgical techniques for the treatment of pilonidal sinus disease: excision with primary closure and excision with open (lay-open) technique.
- Conditions
- Pilonidal Sinus Disease, Sacrococcygeal Pilonidal Sinus, Chronic Infected Sinus Tract, Post-surgical Wound Healing
- Trial name
- NCT07311707
- Testing
- Primary Suturing of Surgical Wound, Open Surgical Wound Management
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Sacrococcygeal Pilonidal Disease
Modified Limberg Procedure Versus Lateral Advancement Flap With Burrow's Triangle Procedure in the Treatment of Pilonidal Sinus
The investigators want to share our study that is the "Comparison of Modified Limberg Flap Transposition and Lateral Advancement Flap Transposition with Burrow's Triangle in the Surgical Treatment of Sacrococcygeal Pilonidal…
- Trial name
- NCT02116738
- Testing
- Flap Transposition Procedures
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ankara Mevki Military Hospital
Recurrence, Postoperative Complication
Videoendoscopic Pilonidal Sinus Surgery
This study examines performing pilonidal sinus surgery minimal invasively with videoendoscopic approach.
- Trial name
- videosinus (NCT01583751)
- Testing
- videoendoscopic resection of pilonidal sinus
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- SB Istanbul Education and Research Hospital
Endoscopic Pilonidal Sinus
Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease
Aim of the work To compare lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing time and return to daily…
- Trial name
- NCT04418310
- Testing
- Lay open and curettage, Endoscopic (E.P.Si.T) method
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Pilonidal Sinus
Limberg-flap: Prospective Data Collection
The investigators think, that the treatment of pilonidal sinus with excision and covering of the defect with a Limberg-flap is a very good treatment option.
- Trial name
- NCT00672555
- Testing
- Limberg-flap
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Cantonal Hospital of St. Gallen
Pilonidal Sinus, Pilonidal Disease
The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children
Chronic wounds that fail to heal over extended periods pose a significant financial burden on the healthcare system, underscoring the urgent need to enhance clinical treatments.
- Trial name
- NCT06391307
- Testing
- Crystallized phenol, Crystallized phenol + Exosome, Crystallized phenol + Stem Cell
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Azizoğlu
Pilonidal Sinus of Natal Cleft
Long-term Outcome After Pit-pick for Simple Pilonidal Sinus Disease
Single-center cohort study of long-term results after pit-pcik for pilonidal sinus disease.
- Trial name
- NCT05027607
- Testing
- Bascom's pit-pick
- Where
- Denmark
- Volunteers
- 158 people
- Sponsor
- Nordsjaellands Hospital
Pilonidal Sinus
Staging System for Chronic Symptomatic Pilonidal Sinus Disease
A staging system was defined based on morphological extent of disease (stage I to stage IV for primary disease, and stage R for recurrent disease). Specific surgical technique was used for each stage.
- Trial name
- NCT02712970
- Testing
- pit-picking technique, Bascom Cleft Lift, Rhomboid excision with the Limberg Flap
- Volunteers
- 367 people
- Sponsor
- Trabzon Numune Training and Research Hospital
Pilonidal Sinus
Study on Surgical Treatment of Pilonidal Sinus Disease
Comparison of limited excision-primary closure, Limberg, and modified Limberg flap techniques for the surgical treatment of pilonidal sinus disease, each performed by a separate surgeon, in terms of postoperative outcomes and…
- Trial name
- NCT02849197
- Testing
- surgery for pilonidal sinus disease
- Volunteers
- 802 people
- Sponsor
- Bezmialem Vakif University
Pilonidal Sinus Disorder
Factors Affecting Wound Dehiscence in Pilonidal Sinus Surgery (ORIPIS)
The goal of this multicenter, prospective, observational study is to investigate factors associated with wound dehiscence following pilonidal sinus surgery.
- Trial name
- NCT07370714
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Ankara Etlik City Hospital
Pilonidal Sinus, Sacrococcygeal Pilonidal Disease
Karydakis Flap Versus Burow's Triangle Advancement Flap in the Surgery of Sacrococcygeal Pilonidal Sinus Disease
In this study, we aim to compare the Karydakis flap and Burow's Triangle Advancement Flap techniques applied in the surgical treatment of pilonidal sinus in terms of complications, time to return to normal activity, and…
- Trial name
- NCT05289297
- Testing
- Karydakis Flap Procedure, Burow's Triangle Advancement Flap Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul Sultanbeyli State Hospital
Pilonidal Disease
Pain Control for Laser Epilation in Pilonidal Disease
It's unclear if the application of topical lidocaine prior to laser follicle ablation is effective in reducing discomfort from the procedure.
- Trial name
- NCT06640946
- Testing
- Topical lidocaine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- David Mooney
Non-abscessed Pilonidal Cyst
Cost-utility Analysis of the Use of a Laser Fiber in the Management of Non-abscessed Pilonidal Cyst
This multicenter, prospective, randomized, open-label trial compares laser fiber treatment with conventional surgery in adults with non-abscessed pilonidal cyst.
- Trial name
- ACONIDAL (NCT07652099)
- Testing
- Laser fiber treatment, Conventional surgery
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Elsan
Pilonidal Sinus
Mid-line Excision Versus Karydakis Operation for Pilonidal Sinus
The trial compares excision in the midline at surgery for pilonidal disease versus excision lateral of the midline (Karydakis operation) at surgery for pilonidal disease by randomly allocating patients with pilonidal disease to…
- Trial name
- NCT00412659
- Testing
- Surgery for pilonidal disease, midline excision, Surgery for pilonidal disease, Karydakis operation
- Where
- 2 sites in Sweden
- Volunteers
- 125 people
- Sponsor
- Umeå University