Clinical trials: Pilonidal Sinus Disease
Pilonidal Disease, Pilonidal Cyst/Fistula
MIPE for Pilonidal Disease
Pilonidal disease often presents as a chronic, relapsing condition. A variety of procedures are used in the management of pilonidal disease, with varying degrees of morbidity, disease-free interval, and long-term success.
- Conditions
- Pilonidal Disease, Pilonidal Cyst/Fistula, Pilonidal Sinus Without Abscess, Pilonidal Cyst Without Abscess
- Trial name
- NCT03772873
- Testing
- minimally invasive pilonidal excision
- Where
- 10 sites in United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pilonidal Disease, Pilonidal Disease of Natal Cleft
Topical Anti-Androgens in Pilonidal Sinus Disease
The goal of this randomized clinical trial is to test the topical drug clascoterone in patients with pilonidal disease, which is a common, benign skin condition of the gluteal cleft.
- Conditions
- Pilonidal Disease, Pilonidal Disease of Natal Cleft, Pilonidal Sinus, Pilonidal Cyst
- Trial name
- NCT06286397
- Testing
- 1% Clascoterone, Vehicle Cream
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Pennsylvania
Pilonidal Disease of Natal Cleft
Effect of Platelet Rich Plasma on Healing of Operated Pilonidal Sinus by Open Method
The aim of the study is to assess the healing promotion effect of platelet rich plasma in patient being operated for sacrococcygeal pilonidal sinus disease by open excision
- Trial name
- NCT04430413
- Testing
- Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Infected Pilonidal Sinus
Radiofrequency Treatment for Pilonidal Disease : Safety of Use, Efficacy and Patient Satisfaction at 6 Months
Infected pilonidal sinus is a common suppuration that occurs twice as often in men as in women, usually between the ages of 15 and 30. Clinical diagnosis is easy, whether the presentation is acute or chronic.
- Trial name
- RaTPiD (NCT05855733)
- Testing
- radiofrequency treatment
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Pilonidal Sinus Treatment, Pilonidal Sinus Disorder
Phenol or Laser: Best Minimally Invasive Treatment for Pilonidal Sinus?
Pilonidal sinus disease is a common condition. There is still ongoing research on the ideal treatment. Pilonidal sinus disease is most common in men between the ages of 20 and 30.
- Conditions
- Pilonidal Sinus Treatment, Pilonidal Sinus Disorder, Surgical Outcomes
- Trial name
- NCT06721169
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Mersin University
Sacrococcygeal Pilonidal Sinus Disease
Hardware Wound Healing In Surgical Treatment Of Sacrococcygeal Pilonidal Sinus Disease
THEME RELEVANCE. Sacrococcygeal pilonidal sinus disease (SPD) is a congenital disease that's well spread and constitutes 1-2% of all surgical pathologies. In all Coloproctological pathologies, the disease composes 14-20% (G.I.
- Trial name
- HWHPSD (NCT01876537)
- Testing
- Hardware wound healing, Usual Surgery
- Where
- Russia
- Volunteers
- 39 people
- Sponsor
- Voronezh N.N. Burdenko State Medical Academy
Infected Pilonidal Sinus
Radiofrequency Treatment for Pilonidal Disease : Clinical Investigation on Safety of Use, Efficacy and Patient Satisfaction at 6 Months
Infected pilonidal sinus is a common suppuration that occurs twice as often in men as in women, usually between the ages of 15 and 30. Clinical diagnosis is easy, whether the presentation is acute or chronic.
- Trial name
- RFKP (NCT07557589)
- Testing
- Radiofrequency treatment
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- CHI MONT DE MARSAN ET PAYS DES SOURCES
Anorectal Diseases, Hemorrhoids
Comparative Analysis of Hypobaric Versus Hyperbaric Bupivacaine for Spinal Anesthesia in Day-Case Anorectal Surgery
Spinal anesthesia for anorectal surgery ( fistulotomy, fissure repair, pilonidal sinus excision,hemorrhoidectomy..) is a popular and widely used method characterized by rapid onset, delivery, easy mobilization and short hospital…
- Conditions
- Anorectal Diseases, Hemorrhoids, Anal Polyp, Pilonidal Sinus
- Trial name
- NCT05409820
- Testing
- use of different spinal anesthesia techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Pilonidal Sinus, Pilonidal Disease
Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone)
The goal of this randomized clinical trial is to establish the efficacy of 'pit picking with laser therapy' versus 'pit picking alone' on both short and long-term outcomes in patients of 12 years and older with primary pilonidal…
- Conditions
- Pilonidal Sinus, Pilonidal Disease, Pilonidal Sinus of Natal Cleft, Pilonidal Disease of Natal Cleft
- Trial name
- LA POPA (NCT06140199)
- Testing
- Pit-picking surgery, Pit-picking surgery with Sinus Laser assisted Closure
- Volunteers
- 482 people
- Sponsor
- dr. IJM Han-Geurts
Pilonidal Sinus
A Single Center Experience in the Management of Pilonidal Disease
Sacrococcygeal pilonidal disease (PND) is a common entity affecting the skin and subcutaneous tissue of the upper portion of the natal cleft of the buttocks.
- Trial name
- NCT05892198
- Testing
- surgery
- Volunteers
- 101 people
- Sponsor
- Mansoura University
Pilonidal Disease
A Trial in Mini-invasive Pilonidal Sinus Disease Surgery
Pilonidal sinus disease is a chronic acquired disease leading to significant morbidity and healthcare costs in young man and women.
- Trial name
- NCT06964763
- Testing
- surgery + laser, surgery + fibrine glue
- Where
- Finland
- Volunteers
- 188 people
- Sponsor
- Helsinki University Central Hospital
Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess
SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study.
Pilonidal sinus disease (PSD) is a chronic inflammatory condition of the sacrococcygeal region that frequently affects young adults, often causing pain, drainage, and recurrent infection.
- Conditions
- Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess, Pilonidal Sinus, Pilonidal Cysts
- Trial name
- SiLaC-LaPaz (NCT07260643)
- Testing
- SilaC
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Paz
Pilonidal Sinus Disease, Laser Therapy
Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus
This study compares two treatment approaches for pilonidal sinus disease: laser treatment alone versus laser treatment combined with phenol application.
- Trial name
- PLEPS (NCT07023952)
- Testing
- Laser Treatment, Crystallized Phenol
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Pilonidal Disease, Pilonidal Cyst
Feasibility of a Novel Technique for Pilonidal Wound Healing
Pilonidal disease (PD) is a chronic disease with a major impact on patient quality of life and productivity. Thus, wound healing would have a significant effect on patient quality outcomes, patient quality of life, and healthcare…
- Conditions
- Pilonidal Disease, Pilonidal Cyst, Pilonidal Sinus
- Trial name
- NCT02330159
- Testing
- Novel Wound Healing Protocol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Southeast Clinical Research Associates, Houston, Texas
Pilonidal Sinus
Bascom Cleft Lift Versus Limberg Flap for Sacrococcygeal Pilonidal Sinus
A pilonidal sinus is a cyst on the natal cleft of the buttocks that often contains hair and skin debris. The condition is common and requires surgery to be cured. Several surgical procedures are described in literature.
- Trial name
- NCT01337869
- Testing
- Bascom Cleft Lift, Limberg Flap
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trabzon Numune Training and Research Hospital
Pilonidal Disease, Pilonidal Sinus
Non-Powered Negative Pressure Wound Therapy vs Open Technique for Pilonidal Disease
Pilonidal Disease is disease of young patients with significant morbidity and is difficult to treat. Currently multiple methods are practiced for the treatment of the disease, two of them are preferred over others and practice…
- Trial name
- NPWTvsOT (NCT03483480)
- Testing
- NPWT for Pilonidal Surgery, Excision of Pilonidal sinus with normal dressing
- Where
- Ireland
- Volunteers
- 32 people
- Sponsor
- The National Children's Hospital, Tallaght
Pilonidal Sinus Disease
VAAPS Combined With Loose Seton Drainage for Postoperative Self-Care: A Prospective Single-Arm Cohort Study
Pilonidal sinus is a chronic infection of the sacrococcygeal skin that mainly affects young adults. Traditional surgery leaves large wounds requiring weeks of daily dressing changes away from home.
- Trial name
- PKUPH-PS01 (NCT07855107)
- Testing
- VAAPS with Loose Seton Drainage
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University People's Hospital
Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease
The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus
"Assessment of postoperative pain with conventional and tumescent local anesthesia in the laser treatment of pilonidal sinus." The aim of this study is to: examine the possible difference in postoperative pain between two local…
- Conditions
- Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease, Pilonidal Sinus Treatment, Laser Ablation
- Trial name
- NCT07408414
- Testing
- local anesthesia using 2% lidocaine, SiLaC, Questionnaire and physical examination
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Opća županijska bolnica Požega
Pilonidal Disease
Comparison of Laser Destruction of Pilonidal Sinus Disease (SILAC) and Bascom II Procedure.
Surgical treatment witn lateralization of intergluteal cleft is still gold standard for pilonidal sinus disaease. But nowadays minimally invasive treatment methods such as the use of a diode laser (SiLac, Sinus Laser Closure) to…
- Trial name
- SI-BAS (NCT05715983)
- Testing
- Bascom II procedure, SiLaC
- Where
- Russia
- Volunteers
- 164 people
- Sponsor
- Russian Society of Colorectal Surgeons
Pilonidal Sinus
The Most Frequently Preferred Surgical Method In The Treatment Of Sacrococcygeal Pilonidal Disease
There is no consensus on which procedure is the ideal surgical method in the treatment of sacrococcygeal pilonidal disease (SPD).
- Trial name
- NCT04599517
- Where
- Turkey (Türkiye)
- Volunteers
- 6,748 people
- Sponsor
- Konya Meram State Hospital