Clinical trials: Placebo-Post
Anemia
A Study to Evaluate the Safety of Epoetin Alfa and Its Effectiveness in Facilitating the Presurgical Collection of Blood From Anemic Patients for Possible Self-transfusion During and After Scheduled Joint Surgery.
The purpose of this study is to evaluate the safety of epoetin alfa and its effectiveness in facilitating the presurgical collection of blood from anemic patients for possible self-transfusion during and after scheduled joint…
- Trial name
- NCT00270062
- Testing
- epoetin alfa
- Volunteers
- 77 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Vasalgia, Headache
The Effect of Sphenopalatine Ganglion Block on Headache and Vasalgia
The purpose of this study is to evaluate the effect of sphenopalatine ganglion block (SPG block) on headache and veisalgia (hangover) the day after attending the metal festival Copenhell.
- Conditions
- Vasalgia, Headache, Hangover
- Trial name
- NCT07060586
- Testing
- Sphenopalatine Ganglion Block
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Systemic Inflammatory Response Syndrome, Postoperative Shock
The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery
In this randomized, double-blind, placebo-controlled study, the investigators will assess whether preoperative disruption of the gut microbiota by a course of broad spectrum antibiotics will attenuate the postoperative systemic…
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Shock, Coronary Artery Disease, Extracorporeal Circulation; Complications
- Trial name
- REMEDI (NCT03939273)
- Testing
- Vancomycin Oral, Metronidazole Oral, Ciprofloxacin Pill
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Radboud University Medical Center
Macular Edema
Prophylactic Nepafenac and Ketorolac Versus Placebo in Patients Undergoing Cataract Surgery
Assess prophylactic efficacy of topical non-steroidal anti-inflammatory drops in preventing macular edema. Patient undergoing uncomplicated cataract surgery will be enrolled and randomized to nepafenac, ketorolac, or placebo.
- Trial name
- PNK (NCT01395069)
- Testing
- Nepafenac 0.1%, Ketorolac 0.5%
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Queen's University
Neuropathic Pain, Chronic Pain
Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children
This study concerns children aged to 12 to 17-years with local chronic neuropathic pain after trauma or surgery. It is a multicentric randomized controlled superiority trial in parallel arms : experimental arm: Capsaicin 8%…
- Trial name
- CAPSAPED (NCT05997979)
- Testing
- Capsaicin 8% patch, Hydrocolloid dressing
- Where
- 10 sites in France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Brest
Healthy
Study to Evaluate the Presence of a Hangover Effect in Healthy Adults After Administration of Songha® Night Tablets
Study to determine the presence of a hang-over effect in healthy volunteers the day after the administration of Songha® Night
- Trial name
- NCT02273453
- Testing
- Songha® Night, Oxazepam
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Ebola Hemorrhagic Fever
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers
The purpose of this study is to evaluate the safety and tolerability of healthy male and female subjects with intravenous (IV) infusions of AVI 7537 compared to matched placebo in and to evaluate the pharmacokinetics (PK).
- Trial name
- NCT01593072
- Testing
- AVI-7537, Normal Saline Solution (NSS)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sarepta Therapeutics, Inc.
Healthy Volunteers
A Dose-Block Randomized, Placebo Controlled (Double-blind), Active Controlled(Open-label), Dose-escalation Study
The study design of this trial is a Dose-Block Randomized, Placebo controlled (Double-blind), Active Controlled(Open-label), Dose-escalation.
- Trial name
- NCT02175056
- Testing
- HL2351, Kineret(Anakinra)
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Handok Inc.
Non-Small Cell Lung Cancer Stage III
A Study of CS1001 in Subjects With Stage III Non-Small Cell Lung Cancer
This is a randomized, double-blind, placebo-controlled, multicenter phase III study to evaluate the efficacy and safety of CS1001 in subjects with locally advanced/unresectable (Stage III) non-small cell lung cancer that has not…
- Trial name
- NCT03728556
- Testing
- CS1001 monoclonal antibody
- Where
- China
- Volunteers
- 381 people
- Sponsor
- CStone Pharmaceuticals
Anesthesia, General
A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part A: Japanese Participants (P05956)
The objective of this trial was to establish the dose-response of T2 (the amplitude of the first response of second twitch to train of four (TOF) stimulation, expressed as percentage of control first twitch,T1) in Japanese and…
- Trial name
- NCT00591409
- Testing
- sugammadex
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Dandruff
Evaluation of the Efficacy of SeS2 Shampoo on Subjects Having Dandruff
A shampoo containing SeS2 was evaluated versus placebo on healthy subjects suffering from dandruff in order to assess clinical benefits and its impact on fungal and bacterial scalp microbiota.
- Trial name
- NCT05506592
- Testing
- dermatological product
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Healthy
Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446
This study is designed to evaluate the safety, tolerability and PK of AZD1446 in Subjects when given as multiple dose administration for either 7 Days (Day 1 single dose, Day 2-6 multiple doses) in Part A and optionally at…
- Trial name
- NCT00902993
- Testing
- AZD1446
- Where
- 2 sites in Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Hepatocellular Carcinoma
A Study of Ramucirumab (IMC-1121B) Drug Product (DP) and Best Supportive Care (BSC) Versus Placebo and BSC as 2nd-Line Treatment in Participants With Hepatocellular Carcinoma After 1st-Line Therapy With Sorafenib
This is a Phase 3 multicenter, randomized study evaluating the safety and efficacy of ramucirumab DP plus BSC as a double-blind, placebo-controlled (placebo plus BSC) comparison.
- Trial name
- REACH (NCT01140347)
- Testing
- Ramucirumab DP (IMC-1121B), BSC
- Where
- 146 sites in United States, Australia and 25 more
- Volunteers
- 565 people
- Sponsor
- Eli Lilly and Company
Early Pregnancy Failure
Comparing Two Medical Treatments for Early Pregnancy Failure.
This study aims to compare whether a combination of two drugs (Mifepristone and misoprostol) are superior compared to using only one of these drugs (Misoprostol) as medical treatment for a miscarriage.
- Trial name
- Triple M (NCT03212352)
- Testing
- Mifepristone, Misoprostol
- Where
- 13 sites in Netherlands
- Volunteers
- 342 people
- Sponsor
- Radboud University Medical Center
Asthma
Study on the Effects of an AMP Challenge on Asthmatic Patients Following Treatment With Fluticasone Propionate
Inhaling AMP causes an inflammatory response in the lung. This study will investigate whether 5-days of treatment with fluticasone propionate protects the lung from responding to the AMP in this way.
- Trial name
- NCT00400855
- Testing
- Fluticasone propionate
- Where
- 2 sites in New Zealand
- Volunteers
- 49 people
- Sponsor
- GlaxoSmithKline
Chronic Fatigue Syndrome
Clinical Trial to Measure the Maximun HR After ReConnect ® Supplementation vs. Placebo in CFS.
The main objective is evaluate to safety and efficacy of oral Reconnect ® (food supplementation composed by Coenzyme Q10, NADH, phosphoserine y vitamin C) on the maximum HR during an exercise test in CFS
- Trial name
- ReConnect (NCT02063126)
- Testing
- ReConnect (NADH plus CoQ10)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Posttraumatic Stress Disorder
Pilot Study of the Safety and Efficacy of Four Different Potencies of Smoked Marijuana in 76 Veterans With PTSD
This pilot study gathered preliminary evidence of the safety and efficacy of four potencies of smoked cannabis to manage chronic, treatment-resistant PTSD among veterans: (1) High THC/ Low CBD (High THC), (2) Low THC/High CBD…
- Trial name
- NCT02759185
- Testing
- High THC cannabis, High CBD cannabis, THC/CBD cannabis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Multidisciplinary Association for Psychedelic Studies
Cancer, Breast Cancer
Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours
Add-Aspirin aims to assess whether regular aspirin use after standard curative therapy can prevent recurrence and improve survival in individuals with non-metastatic common tumours.
- Conditions
- Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT02804815
- Testing
- Aspirin 100mg, Aspirin 300mg
- Where
- 82 sites in Ireland, United Kingdom
- Volunteers
- 11,000 people
- Sponsor
- University College, London
Preterm Labor
Vaginal Progesterone for the Prolongation of Pregnancy After Arrested Pre-term Labor
Patients diagnosed with arrested pre-term labor following tocolytics at 24-34 gestational weeks will be randomly allocated to receive either vaginal micronized progesterone 400 mg/day or no treatment.
- Trial name
- NCT02430233
- Testing
- micronized progesterone 400 mg (Utrogestan)
- Where
- 3 sites in Israel
- Volunteers
- 129 people
- Sponsor
- HaEmek Medical Center, Israel
Knee Injuries
Effects of Intraarticular IL1-Ra on Pain and Inflammatory Mediators After Knee Arhroscopy
This project investigates the relation between acute pain and local inflammation. Pain reported by the patients for knee arthroscopy are compared with local changes in inflammatory mediators by using microdialysis technique.
- Trial name
- NCT01997138
- Testing
- Anakinra 100 mg in 2 ml saline IA
- Where
- Norway
- Sponsor
- Oslo University Hospital
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