Clinical trials: Placebo-Post
Gynecology
An Endometrial Cancer Chemoprevention Study of Metformin
The goal of this clinical research study is to learn about the effects of metformin and/or a program called "lifestyle intervention" on the endometrium (inner lining of the uterus) in post-menopausal women who are also obese…
- Trial name
- NCT01697566
- Testing
- Metformin, Endometrial Biopsy, Lifestyle Intervention
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy
Assess the Safety, Tolerability and Pharmacokinetics of AZD5213 After Single and Multiple Ascending Oral Doses in Healthy Young and Elderly Japanese Subjects
The purpose of this study is to investigate the safety, tolerability and pharmacokinetics of AZD5213 in healthy young and elderly Japanese subjects
- Trial name
- NCT01335451
- Testing
- AZD5213
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Peritonsillar Abscess
Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage
This study aims to look at the necessity for prescribing antibiotics post-drainage of peritonsillar abscesses (PTA). This will be a single-blinded randomized-control trial with two arms - patients receiving placebo versus those…
- Trial name
- PTA (NCT01715610)
- Testing
- Clavulin, Clindamycin
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Posttraumatic Stress Disorder
Modafinil in the Treatment of PTSD (Posttraumatic Stress Disorder)
The purpose of this study is to determine if modafinil is more effective than placebo in the treatment of posttraumatic stress disorder (PTSD) in male combat veterans who have been deployed to Iraq or Afghanistan.
- Trial name
- NCT01726088
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Biomedical Research Foundation
Asthma
A Study to Compare the Efficacy and Safety of Different Dosings of Olodaterol Administered With the Respimat® Inhaler in Patients With Moderate to Severe Asthma
This study will compare efficacy and safety of different regimens of olodaterol administration in asthma (once daily, twice daily) with placebo in a complete cross-over design each within one of the two daily dose groups (medium…
- Trial name
- NCT01311661
- Testing
- Olodaterol low daily dose twice daily, Olodaterol medium daily dose twice daily
- Where
- 36 sites in United States, Austria and 4 more
- Volunteers
- 206 people
- Sponsor
- Boehringer Ingelheim
Acute Postoperative Pain, Dental Pain
A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction
The primary objective of this trial is to assess the safety and tolerability of single, ascending doses of CYT-1010 in healthy male and female volunteers and in the treatment of acute postoperative pain after third molar…
- Trial name
- NCT07905105
- Testing
- CYT-1010
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cytogel Pharma, LLC
Pain, Post-surgical
Analgesic Efficacy Of Valdecoxib In Patients Following Bunion Surgery
To assess the analgesic efficacy and general safety of 2 dosing regimens of valdecoxib compared to placebo on the first post-operative day in patients with moderate or severe pain following bunionectomy surgery.
- Trial name
- NCT00653354
- Testing
- valdecoxib
- Where
- 21 sites in United States
- Volunteers
- 360 people
- Sponsor
- Pfizer
Autism Spectrum Disorder (ASD)
Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children and Adolescents Aged From 7 to Less Than 18 Years Old With Autism Spectrum Disorder
The purpose of this study was to evaluate the efficacy and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.
- Trial name
- NCT03715166
- Testing
- Bumetanide Oral Solution
- Where
- 45 sites in Brazil, France and 8 more
- Volunteers
- 211 people
- Sponsor
- Institut de Recherches Internationales Servier
Insomnia
Ramelteon for Complex Insomnia in Veterans With PTSD
Obstructive sleep apnea is commonly reported in Veterans with post-traumatic stress disorder, which can potentiate symptoms of anxiety and depression, daytime symptoms and worsen nightmares.
- Trial name
- DORMI (NCT03265951)
- Testing
- Ramelteon, Usual Care
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Atrial Fibrillation
QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)
Atrial fibrillation (AF) is a type of irregular heart rhythm due to electrical signal disturbances of the heart. It is a very common arrhythmia and the risk of developing AF increases with age and with other risk factors such as…
- Trial name
- QOL-CAFRCT (NCT05136131)
- Testing
- Electrical cardioversion
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Internal Hemorrhoids, Postoperative Pain After Endoscopic Rubber Band Ligation
Nitroglycerin Ointment for Pain Relief After Endoscopic Hemorrhoid Band Ligation
This study is designed to evaluate whether nitroglycerin ointment can reduce pain after endoscopic rubber band ligation for internal hemorrhoids.
- Trial name
- NCT07391501
- Testing
- Nitroglycerin Ointment
- Volunteers
- 68 people
- Sponsor
- Ying Zhu
Post Exercise Inflammation, Exercise Recovery
Effect of Maolactin™ FMR on Exercise Recovery, Inflammation, and Muscle Comfort in an Otherwise Healthy Population
This is a double blind, randomised, placebo-controlled, parallel-group trial to evaluate the effect of Maolactin FMR supplementation on post exercise inflammation, exercise recovery and muscle fatigue and pain in an otherwise…
- Conditions
- Post Exercise Inflammation, Exercise Recovery, Muscle Fatigue, Muscle Pain
- Trial name
- NCT06436781
- Testing
- Maolactin, Maltodextrin
- Where
- Australia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Healthy
A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Ascending Doses of AZD5069 in Healthy Volunteers
The purpose of this study is to explore the safety and tolerability of AZD5069 at steady-state, following twice a day oral dosing in healthy subjects.
- Trial name
- NCT01051505
- Testing
- AZD5069
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Adolescent Idiopathic Scoliosis (AIS)
Intravenous Dexamethasone for ESP Block Analgesia in Children Undergoing Idiopathic Scoliosis Surgery
This randomized, double-blind, placebo-controlled study will evaluate the effect of intravenous dexamethasone on postoperative analgesia in children and adolescents undergoing surgery for idiopathic scoliosis with bilateral…
- Trial name
- NCT07890220
- Testing
- Dexamethasone (0.1 mg/kg), Dexamethasone (0.2 mg/kg)
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Post-COVID Condition, Fatigue Symptom
Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVID
The primary purpose of this phase 2a study is to compare the efficacy of abrocitinib to placebo in improving severe fatigue in non-hospitalized adults with symptomatic Post-COVID Condition (PCC) (also called Long COVID).
- Trial name
- CLEAR-LC (NCT06597396)
- Testing
- Abrocitinib
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Beth Israel Deaconess Medical Center
Gastric Neoplasm
The Effect of Perioperative Intravenous Magnesium on Pain After Endoscopic Submucosal Dissection for Gastric Neoplasm: Prospective Randomized Double-blind Placebo Controlled Study
Endoscopic submucosal dissection (ESD) is an effective treatment for early gastric cancer or premalignant lesions in the stomach.
- Trial name
- NCT02235246
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Type 2 Diabetes Mellitus
Multiple Ascending Dose Trial of BYK324677 in Healthy Volunteers
This monocenter trial is conducted to obtain first data on safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) after multiple ascending doses of BYK324677 in humans.
- Trial name
- NCT01386541
- Testing
- BYK324677
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Nycomed
Laparoscopic Hysterectomy, Postoperative Recovery
Perioperative Duloxetine for Pain Management After Laparoscopic Hysterectomy
The aim of the investigators of the study is to evaluate the effect of peri-operative duloxetine on post-operative recovery in patients undergoing laparoscopic hysterectomy.
- Conditions
- Laparoscopic Hysterectomy, Postoperative Recovery, Postoperative Pain
- Trial name
- NCT03350334
- Testing
- Duloxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Clinical Trial to Assess the Improvement of Fatigue, Sleep Problems, Anxiety / Depression, Neurovegetatives Alterations and Quality of Life After the Administration of ImmunoVita® in Chronic Fatigue Syndrome Patients
Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (CFS / MS) is a medical entity characterized mainly by debilitating and prolonged fatigue lasting more than 6 months, post-exertion fatigue (physical and / or…
- Trial name
- NCT04301609
- Testing
- Active
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Vitae Health Innovation
Ulcer
H. Pylori Eradication on Healing of Iatrogenic Gastric Ulcer by Endoscopic Mucosal Resection
This study will evaluate the effect of Helicobacter pylori eradication therapy on the healing of iatrogenic gastric ulcer caused by endoscopic mucosal resection of gastric neoplastic lesions and is a multicenter, randomized…
- Trial name
- NCT00926809
- Testing
- Lansoprazole (proton pump inhibitor), amoxicillin, clarythromycin
- Where
- 6 sites in South Korea
- Volunteers
- 232 people
- Sponsor
- Korean College of Helicobacter and Upper Gastrointestinal Research
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