Clinical trials: Placenta Accreta Spectrum
Placenta Accreta
Placenta Accreta Spectrum Protocol
Aim of this project is to study diagnosis and management approaches of PAS and to assess safety and efficacy of different conservative approaches compared to planned hysterectomy.
- Trial name
- NCT04384510
- Testing
- Planned Cesarean hysterectomy, Conservative management
- Where
- Egypt
- Volunteers
- 1,500 people
- Sponsor
- Assiut University
Placenta Accreta Spectrum, Cesarean Hysterectomy
Early vs Late Bladder Dissection During CS Hysterectomy in Patients With PAS With Bladder Invasion
Thirty-six singleton pregnant women with PAS and bladder invasion; total anterior or anterolateral invasion, who were scheduled for cesarean hysterectomy were randomly assigned into two equal groups Group 1: included 18 pregnant…
- Trial name
- NCT05752513
- Testing
- Late bladder dissection, early bladder dissection
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Placenta Previa, Placenta Accreta
Management of Placenta Accreta Spectrum
placenta accreta spectrum is group of disorders which have a depate about the best way of management. this is a descriptive study about the best techniques to reduce morbidity and mortalities related to it.
- Trial name
- NCT04609527
- Testing
- Management of placenta accreta spectrum
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Placenta Accreta Management
Total Lower Uterine Segmentectomy With Adjunctive Mechanical Towel Compression for the Surgical Management of Placenta Accreta Spectrum Disorders
The goal of this observational study is to evaluate the feasibility and safety of utilizing adjunctive mechanical towel compression during TLS-CCA, measured primarily by estimated intraoperative blood loss in patient with…
- Trial name
- NCT07706062
- Volunteers
- 30 people
- Sponsor
- Assiut University
Placenta Accreta Spectrum
Comparison Between Cervical Tourniquet and Uterine Artery Ligation Prior to Segmental Resection Approach
The study will compare a modified surgical approach for preserving fertility and minimizing hemorrhage in morbidly adherent placenta during cesarean section with a cervical tourniquet against uterine artery ligation.
- Trial name
- NCT06483724
- Testing
- cervical tourniquet, uterine artery ligation
- Volunteers
- 82 people
- Sponsor
- Minia University
Placenta Accreta Spectrum
Evaluation of Different Surgical Approaches Used for Conservative Management of Placenta Accreta Spectrum in Sohag University Hospital
The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and…
- Trial name
- NCT05510076
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Placenta Accreta
A Comparison Between Bladder Dissection Before and After Uterine Incision During Cesarean Section for Placenta Accreta Spectrum: A Randomized Controlled Study
The worldwide incidence of placenta accreta spectrum is increasing, following the trend of rising caesarean delivery. It is an heterogeneous condition associated with a high maternal morbidity and mortality rate (Jauniaux et al.…
- Trial name
- NCT06957184
- Testing
- bladder dissection in placenta accreta spectrum
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Placenta Accreta Spectrum Disorders,Previous Cesarean Section
Prospective Cohort Observational Study of Placenta Accreta Spectrum Disorders
The incidence of placenta accreta spectrum disorders has shown an increasing trend worldwide due to the increase of cesarean section rate.
- Trial name
- NCT06021964
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Guangzhou Medical University
Placenta Accreta
Histerectomy Vs Partial Myometrial Resection for Placenta Accreta Spectrum
Currently, Placenta Accreta Spectrum (PAS) has two treatment options: hysterectomy (completely removing the uterus) and partial myometrial resection (resecting the part of the uterus affected by this pathology).
- Trial name
- RCT-PAS (NCT05013749)
- Testing
- Hysterectomy, Partial Myometrial Resection
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Fundacion Clinica Valle del Lili
Blood Loss, Repeat Cesarean Section
Cesarean Scar Pregnancy and Clinical Outcomes
This study is a prospective cohort study, led by Prof. Zhao Yangyu, from the Department of Gynecology \& Obstetrics, Peking University Third Hospital.
- Conditions
- Blood Loss, Repeat Cesarean Section, Maternal Transmission, Hysterectomy
- Trial name
- NCT05481606
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Placenta Accreta Spectrum
Conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique With or Without Hayman Sutures
This study evaluates whether adding Hayman sutures in the conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique reduces intraoperative blood loss and improves outcomes
- Trial name
- NCT07519993
- Testing
- Kasr Al-Ainy Technique Alone, Kasr Al-Ainy Technique + Hayman Sutures
- Volunteers
- 48 people
- Sponsor
- Cairo University
Placenta Previa, Placenta Accreta
Outcomes of Placenta Accreta Spectrum Disorders Surgery in Relation to Placenta Accreta Scoring Index
Using of Ultra sound in assessment of Placenta Accreta Index to predict the surgical outcomes of Placenta accreta
- Trial name
- NCT06220760
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Previa, Placenta Accreta Spectrum
Planned Delivery at 37 Versus 36 Weeks in Pregnancies With Placenta Previaand Accreta
Current clinical practice guidelines recommend planned cesarean delivery(CD) at 34-37 weeks of gestation in pregnant women with placenta previa and accreta.
- Conditions
- Placenta Previa, Placenta Accreta Spectrum, Antepartum Bleeding, Emergency Cesarean Section
- Trial name
- NCT07025954
- Testing
- Cesarean delivery
- Where
- 6 sites in China
- Volunteers
- 600 people
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Placenta Accreta, Cesarean Hysterectomy
Conservative Treatment of PAS With or Without IIL
In the current study, the investigators aimed to compare the benefits of internal iliac ligation in placenta accreta spectrum
- Conditions
- Placenta Accreta, Cesarean Hysterectomy, Pelvic Devascularization
- Trial name
- PASIIL (NCT05232981)
- Testing
- Ligation of the bilateral internal iliac arteries, Shehat's technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Pathophysiology of Placenta Accreta
Impact of Netrin-1 in the Pathophysiology of Placenta Accreta Spectrum
The main goal of this study is to assess the role of Netrin 1, neogenin and ZEB1 in PAS-associated invasion
- Trial name
- NCT04628169
- Testing
- no intervention applied
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Accreta Spectrum
Effectiveness of REBOA in Reducing Blood Loss During Cesarean Section in Patients with PAS
Obstetric hemorrhage is one of the leading causes of maternal mortality and morbidity worldwide. The major risk factors for obstetric hemorrhage include placenta previa and placenta accreta spectrum (PAS) disorders.
- Trial name
- NCT06721182
- Testing
- REBOA
- Volunteers
- 100 people
- Sponsor
- Nazarbayev University
Placenta Accreta Spectrum, Placenta Previa
Hematological and Coagulation Markers in Predicting Placenta Accreta Spectrum in Placenta Previa
Placenta accreta spectrum (PAS) is a serious pregnancy complication where the placenta attaches too deeply into the wall of the uterus.
- Trial name
- NCT07826247
- Volunteers
- 130 people
- Sponsor
- Assiut University
Placenta Accreta Spectrum
New Conservative Technique for Placenta Accreta Spectrum
participants diagnosed as placenta accreta spectrum were subjected to cesarean delivery. Investigators manually detected a plan of cleavage through which the placenta was separated followed by closure of defective placental bed.
- Trial name
- percreta (NCT04427592)
- Testing
- ultrasound, closure of uterine wall defect
- Where
- Egypt
- Volunteers
- 159 people
- Sponsor
- Alexandria University
Placenta Accreta Management
Observation of Strategies in Placenta Accreta Spectrum Management
Placenta accreta spectrum (PAS) disorders represent a significant obstetric challenge, characterized by abnormal adherence of the placenta to the uterine wall, leading to potentially life-threatening hemorrhage (ACOG 2020; RCOG…
- Trial name
- NCT07236710
- Volunteers
- 300 people
- Sponsor
- Assiut University
Placenta Accreta Spectrum
High vs. Low Segmental Hysterotomy: Impact on Uterine Wall Defects Post-Cesarean
The purpose of this clinical trial is to compare the incidence of defects in the uterine wall at the site of the scar (niche) and surgical complications when using high-segment versus low-segment hysterotomy, with both…
- Trial name
- HISEAL (NCT06620432)
- Testing
- Low segment hysterotomy, High segment hysterotomy, Crossed hysterorrhaphy
- Where
- Colombia
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinica Valle del Lili