Clinical trials: Placenta Accreta Spectrum
Internal Iliac Artery, Balloon Occlusion
Evaluation of Bilateral Internal Iliac Artery Balloon Occlusion in Placenta Accreta Spectrum Management
This study aims to evaluate the efficacy and safety of bilateral internal iliac artery balloon occlusion in the management of the placenta accreta spectrum.
- Conditions
- Internal Iliac Artery, Balloon Occlusion, Placenta Accreta Spectrum
- Trial name
- NCT06562712
- Testing
- Conventional management, Bilateral internal iliac artery balloon occlusion
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Placenta Accreta
Placenta Accreta Spectrum Management: Uterine Preservation Using JSICA Technique - Retrospective Cross-Sectional Study
The goal of this study is to present the Jakarta Surgical Uterine Conservation (JSICA) technique and its perioperative outcomes in Placenta Accreta Spectrum patients.
- Trial name
- NCT05871645
- Testing
- Jakarta Surgical Uterine Conservation (JSICA) Technique, Standard Hysterectomy
- Where
- Indonesia
- Volunteers
- 323 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Placenta Accreta
A Comparison Between Bladder Dissection Before and After Uterine Incision During Cesarean Section for Placenta Accreta Spectrum: A Randomized Controlled Study
The worldwide incidence of placenta accreta spectrum is increasing, following the trend of rising caesarean delivery. It is an heterogeneous condition associated with a high maternal morbidity and mortality rate (Jauniaux et al.…
- Trial name
- NCT06957184
- Testing
- bladder dissection in placenta accreta spectrum
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Placenta Accreta Spectrum
Comparison Between Cervical Tourniquet and Uterine Artery Ligation Prior to Segmental Resection Approach
The study will compare a modified surgical approach for preserving fertility and minimizing hemorrhage in morbidly adherent placenta during cesarean section with a cervical tourniquet against uterine artery ligation.
- Trial name
- NCT06483724
- Testing
- cervical tourniquet, uterine artery ligation
- Volunteers
- 82 people
- Sponsor
- Minia University
Pathophysiology of Placenta Accreta
Impact of Netrin-1 in the Pathophysiology of Placenta Accreta Spectrum
The main goal of this study is to assess the role of Netrin 1, neogenin and ZEB1 in PAS-associated invasion
- Trial name
- NCT04628169
- Testing
- no intervention applied
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Accreta Spectrum
MOGGE PAR Scores for Prediction of Outcomes of PAS
Placenta accreta spectrum (PAS) is a set of placentation disorders that are associated with trophoblastic invasion through the physiologic decidual-myometrial junction zone.
- Trial name
- PAR (NCT04525001)
- Volunteers
- 200 people
- Sponsor
- Assiut University
Placenta Previa, Placenta Accreta Spectrum
Syncytiotrophoblast-derived Extracellular Vesicles in Placenta Previa and Accreta Spectrum
The main goal of this case-control study is to quantify the levels of circulating syncytiotrophoblast-derived extracellular vesicles (STBEVs) in maternal blood in a population of women with placenta previa and placenta accreta…
- Trial name
- PAS (NCT06867874)
- Testing
- Blood sample
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Placenta Accreta, Third Trimester, Uterine Scar Dehiscence
Ultrasound Model to Help Differentiate Between Placenta Accreta Spectrum and Uterine Dehiscence in 3rd Trimester Pregnancies
By using 2d Ultrasound on 3rd trimester pregnant women, a model is made to help differentiate between placenta accreta spectrum and uterine scar dehiscence before operative action to help prepare multi-disciplinary steps if needed
- Trial name
- NCT07236060
- Testing
- 2D ultrasound doppler
- Volunteers
- 50 people
- Sponsor
- Assiut University
Bladder Injury, Accreta, Placenta
Cystoinflation to Prevent Bladder Injury in Cases of Placenta Accreta Spectrum
Placenta accreta spectrum (PAS) disorders are associated with a high risk of bladder injury .leading to increased morbidity. Cystoinflation, involving controlled retrograde bladder filling, has been proposed as a technique to…
- Trial name
- NCT07050082
- Testing
- Bladder dissection after filling with 200 cc saline solution, Bladder dissection with empty bladder
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Obstetric Anesthesia Problems, Placenta Accreta
Fibrinogen Concentrate and Placenta Acreta Spectrum
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS.
- Trial name
- NCT05938062
- Testing
- the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Placenta Accreta Spectrum, Placenta Accreta
Evaluation of Cervical Invasion and Length in Placenta Accreta Patients
Placenta accreta spectrum (PAS), also called morbidly adherent placenta, is a serious pregnancy problem where the placenta attaches too deeply to the uterus wall and does not come out normally after birth.
- Conditions
- Placenta Accreta Spectrum, Placenta Accreta, Placenta Previa
- Trial name
- NCT07452185
- Volunteers
- 200 people
- Sponsor
- Sohag University
Hemorrhage, Placenta Accreta Spectrum
Prophylactic Occlusion Balloons of Both Internal Iliac Arteries in Caesarean Hysterectomy for PASD
The placenta accreta spectrum is a heterogeneous disorder due to abnormal placental invasion into the uterine wall putting at risk the lives of the patients by causing a massive hemorrhage.
- Conditions
- Hemorrhage, Placenta Accreta Spectrum, Cesarean Section Complications
- Trial name
- NCT06356493
- Testing
- caesarean hysterectomy with prior placement of prophylactic occlusion balloons of both internal iliac arteries, caesarean hysterectomy without prior placement of prophylactic occlusion balloons of both internal iliac arteries
- Where
- 2 sites in Tunisia
- Volunteers
- 38 people
- Sponsor
- Tunis University
Placenta Accreta Spectrum
Diagnostic Accuracy of Placental Thickness in Lower Uterine Segment Measured By Ultrasound in Prediction of Placenta Accreta Spectrum in Patients With Placenta Previa. A Diagnostic Test Accuracy Study
Current prenatal diagnosis of placenta accrete spectrum disorders relies on subjective individual interpretations of visual sonographic findings on grayscale and color Doppler imaging.
- Trial name
- NCT05500404
- Testing
- Ultrasound measurment of placental thickness
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams Maternity Hospital
Placenta Accreta Spectrum
The Application of Comprehensive Prevention and Treatment Strategy of Placenta Accreta Spectrum Disorders
Placenta accreta spectrum (PAS) disorders are pathological attachment of the placenta to myometrium, where trophoblastic cells invade the uterine placental interface.
- Trial name
- NCT06477497
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Placenta Accreta
Bilateral Uterine Artery Ligation in PPC Technique for Management of PAS
Aim of the study Primary outcomes: 1. The effect of bilateral uterine artery ligation in reducing intraoperative bleeding in women underwent PPC as a conservative surgical technique. 2. Decrease surgical time.
- Trial name
- NCT05314595
- Testing
- bilateral uterine artery ligation
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Maternal; Procedure
Total Placenta Previa Associated With the Placenta Accreta Spectrum.
To assess the reliability of placental magnetic resonance imaging measurements in predicting peripartum hysterectomy and neonatal outcomes in patients with total placenta previa.
- Trial name
- PAS (NCT06219564)
- Testing
- Peripartum total abdominal hysterectomy (p-TAH), Cesarean Section (C/S), Neonatal mortality
- Where
- Turkey (Türkiye)
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Placenta Accreta
Paracervical Pouch in Placenta Accreta Spectrum
The study objective is the significance of the ultrasound detection of the paracervical pouch in placenta accreta spectrum. It aimed to evaluate its relation to the degree of placenta accreta spectrum, amount of the blood loss…
- Trial name
- pouch (NCT06100640)
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Alexandria University
Placenta Accreta
Risk Factors for Occurrence of Placenta Accrete Spectrum Following Primary Cesarean Delivery
This study will be conducted on a group of patients undergoing repeat elective caesarean delivery attending at Mansoura university hospital.
- Trial name
- NCT04264169
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University Hospital
Cesarean Section Complications
Comparison of N&H Sandwich Technique and Cesarean Hysterectomy in Management of Placenta Accreta Spectrum
The placenta accreta spectrum (PAS)is one of the most common reasons for cesarean hysterectomy Which associated with high rates of severe maternal morbidity (40%-50%), with reported mortality rates up to 7%.
- Trial name
- NCT03701386
- Testing
- cesarean hysterectomy, N&H sandwich technique
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University Hospital