Clinical trials: Placenta Diseases, Diagnosis
Diabete Mellitus, Foot Ulcer Chronic
Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing
Evaluation of Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing
- Trial name
- NCT07326553
- Testing
- Placental Membrane
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- BioXTek
Placenta Accreta Spectrum
Placenta Accreta Spectrum Outcome After Uterine Conservation
study will be carried out on patients with placenta accreta spectrum having done uterine conservation and recording immediate outcome of conservation regarding success of the procedure, amount of blood loss and amount of blood…
- Trial name
- PAS (NCT04866888)
- Testing
- closure of the uterine wall defect, ultrasound, outpatient hysteroscopy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Cardiometabolic Health, Pregnancy Related
Cardiometabolic Health in First Time Pregnancy
Women who experience placental complications (syndromes) during pregnancy, such as pre-eclampsia (high blood pressure and kidney problems), gestational hypertension (high blood pressure during pregnancy) and fetal growth…
- Conditions
- Cardiometabolic Health, Pregnancy Related, Diabetes, Placental; Syndrome, Dysfunction
- Trial name
- POPPY (NCT05856318)
- Where
- 7 sites in United Kingdom
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Postpartum Hemorrhage
Prophylactic Oxytocin Before Versus After Placental Delivery to Reduce Blood Loss in Vaginal Delivery
Randomized controlled study to assess the efficacy and safety of the timing of administration of prophylactic oxytocin via intramuscular route (before compared to after placental delivery) on blood loss in vaginal delivery.
- Trial name
- NCT03006380
- Testing
- oxytocin
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Placenta Accreta
Placenta Accreta; Total Lower Uterine Segmentectomy With Cervico-corporeal Anastomosis
To study feasibility and safety of Total lower uterine segmentectomy with cervico-corporeal anastomosis in conservative management of placenta accreta
- Trial name
- NCT05419804
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Assiut University
Cerebral Palsy
Safety of Cultured Umbilical or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CP
This trial will study the safety and efficacy of intravenous infusion of cultured umbilical or placental derived mesenchymal stem cells for the treatment of Cerebral Palsy
- Trial name
- NCT05018871
- Testing
- Umbilical or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 15 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Chronic Liver Disease
In Patients With Chronic Liver Diseases(Alcoholic Liver Disease and Non-Alcoholic Fatty Liver Disease), LAENNEC(Human Placenta Hydrolysate) is to Evaluate the Efficacy and Safety of Intravenous Drop
Control group : LAENNEC subcutaneous injection (4 ml) Experimental group : LAENNEC intravenous injection (10 ml)
- Trial name
- NCT06493799
- Testing
- LAENNEC (Human Placenta Hydrolysate) IV, LAENNEC (Human Placenta Hydrolysate) SC
- Where
- South Korea
- Volunteers
- 226 people
- Sponsor
- Green Cross Wellbeing
Kidney Cancer
Studying Genes Using Cord Blood and Placenta Samples From Relatively Healthy Newborns and Samples From Younger Patients With Wilms Tumor
RATIONALE: Studying samples of blood and tissue from newborns and from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01576211
- Testing
- DNA methylation analysis, RNA analysis, allele-specific oligonucleotide real-time quantitative polymerase chain reaction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Fetal Growth Retardation
Antenatal Allopurinol in Intrauterine Growth Restriction
Growth retardation in utero may be caused by uteroplacental vascular insufficiency. When Doppler ultrasound studies of the umbilical artery are abnormal pathological intrauterine growth restriction (IUGR) can be diagnosed.
- Trial name
- NCT00346463
- Testing
- Allopurinol
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- UMC Utrecht
Obesity, Pregnancy
Maternal Body Composition Regulates Placental Function
This study examined the relationships between maternal body composition, placental function, and fetal nutrition and body composition, and sought to determine the most accurate method of maternal body composition analysis in late…
- Trial name
- MBC (NCT02586714)
- Testing
- No intervention
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Rheumatoid Arthritis
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion and Intra-Articular Injection for RA
This trial will study the safety and efficacy of intravenous infusion and intra-articular injection of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Rheumatoid Arthritis
- Trial name
- NCT05003934
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Placental Insufficiency
Reference Ranges for Placental Perfusion Using Magnetic Resonance Imaging (MRI)PLACENTIMAGE
To evaluate the feasibility of functional MRI method developed in an animal model and to construct normal reference ranges for in vivo placental perfusion using functional MRI.
- Trial name
- NCT01092949
- Testing
- MRI
- Where
- France
- Volunteers
- 135 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chorioamnionitis, Intrapartum Fever
Intrapartum Fever: Antibiotics Versus no Treatment
The purpose of this study is to determine whether antibiotics can be safely avoided in women who develop a fever during labor. Because investigators have no accurate tests to determine whether women who develop fever during labor…
- Conditions
- Chorioamnionitis, Intrapartum Fever, Intra-amniotic Infection
- Trial name
- NCT03168178
- Testing
- Standard Antibiotic Treatment, No Antibiotic Treatment
- Where
- United States
- Sponsor
- University of Utah
Alterations of ECM in Umbilical Cord ECM in Preeclampisa, Alterations of ECM in Placenta in Preeclampisa
Extracellular Matrix Remodeling of the Umbilical Cord and Placenta in Preeclampsia
Preeclampsia affects 2% to 8% of all pregnancies and is a major cause of maternal morbidity an mortality worldwide.Althought the primary pathology leading to preeclampsia is remain not known, complex pathophysiologic pathways and…
- Trial name
- NCT01931891
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Primary Mitochondrial Diseases
A First in Human Study to Evaluate the Safety of Infusion of MNV-BM-PLC (Autologous CD34+ Cells Enriched With Placenta Derived Allogeneic Mitochondria) in Patients With Primary Mitochondrial Diseases Associated With Mitochondrial DNA Mutation or Deletion
The study objectives are to evaluate the safety of a single intravenous (IV) infusion of autologous CD34+ cells enriched with placenta-derived allogeneic mitochondria in participant with primary mitochondrial disease associated…
- Trial name
- NCT04548843
- Testing
- Bone Marrow mobilization, Apheresis, MNV-BM-PLC infusion
- Where
- Israel
- Sponsor
- Minovia Therapeutics Ltd.
Venous Leg Ulcer
Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers
This is a randomized controlled trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating venous leg ulcers.
- Trial name
- NCT06930768
- Testing
- Standard of Care, NeoThelium FT
- Volunteers
- 132 people
- Sponsor
- NuScience Medical Biologics, LLC
Fetal Macrosomia
Prediction of Fetal Macrosomia by US
Fetal macrosomia defined as birth weight above 90th centile ,macrosomia occurs in 42-62%of pregnancy complicated by type 1 diabetes mellitus ,in 30-56% of pregnancy complicated by type 2 diabetes mellitus .
- Trial name
- NCT03451838
- Testing
- Ultrasound, HbA1c level in blood
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Aljazeera Hospital
Vitamin A Deficiency
Retinol Status in Preterm Infants and Mothers
Retinol and retinol binding protein were studied in the umbilical cord blood of 44 preterm infants with gestation age of < 30 weeks. Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Trial name
- NCT04780958
- Testing
- Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Premature Birth of Newborn, Infant, Very Low Birth Weight
Delayed Cord Clamping in Preterm Neonates
Delayed cord clamping (DCC) from 30 to 60 seconds allows blood to continue to flow from the placenta through the umbilical cord to the infant, thus resulting in a placental transfusion.
- Conditions
- Premature Birth of Newborn, Infant, Very Low Birth Weight, Delayed Separation of Umbilical Cord, Placental Transfusion
- Trial name
- DCC (NCT02478684)
- Testing
- 30 Seconds of placental blood transfusion, 60 Seconds of placental blood transfusion
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Weill Medical College of Cornell University
Post Partum Haemorrhage
Carbetocin Versus Oxytocin in the Prevention of Post Partum Haemorrhage (PPH) in Women Undergoing Caesarean Sections for Placenta Previa: A Randomised Controlled Trial
The study aims at comparing the roles of carbetocin and oxytocin in the prevention of atonic PPH in women undergoing CS for placenta previa.
- Trial name
- NCT02303418
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University