Clinical trials: Planning
Prostate Cancer
Dose Optimization and Diagnostic Performance in Prostate Cancer (SPARROW [Staging Prostate Cancer With Advanced RM2 Radiotracer Oncologic Workup])
This is an open-label, nonrandomized, multicenter study conducted in two sequential parts: an initial Phase 2 Dose Optimization Period followed by the Phase 3 Diagnostic Performance Period.
- Trial name
- SPARROW (NCT07831824)
- Testing
- [68Ga]-LNTH-2401
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- Lantheus Medical Imaging
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Dravet Syndrome
ZX008 Expanded Access Protocol
The treatment plan for this Expanded Access Protocol is for patients with Dravet syndrome who do not qualify for participation in one of the ongoing ZX008 clinical trials.
- Trial name
- NCT03780127
- Testing
- Fenfluramine Hydrochloride
- Sponsor
- Zogenix, Inc.
Smoking Cessation
A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery
It is possible to offer smoking cessation treatment including varenicline to patients scheduled for elective surgery. This study will evaluate whether or not this will enable some patients to quit smoking for up to 4 weeks prior…
- Trial name
- NCT00889720
- Testing
- Varenicline
- Where
- 2 sites in France, Italy
- Volunteers
- 16 people
- Sponsor
- Pfizer
Contraception, Gender Equity
Postpartum Integration of Vaccines and Contraception Trial
This study aims to examine how to implement a gender-transformative post-partum family planning program integrated into community-based infant vaccination services, and to evaluate preliminary effectiveness of this approach on…
- Trial name
- PIVoT (NCT05732142)
- Testing
- Postpartum Integration of Vaccines and Contraception Through Gender-Transformative Programming(PIVoT)
- Where
- 2 sites in United States, India
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Prostate Cancer
The Use of Transperineal Ultrasound for Radiation Therapy Treatment Planning and Image Guidance in the Treatment of Prostate Cancer
This study is being done to find out if transperineal ultrasound (TPUS) can help define the prostate gland for radiation treatment planning and improve upon current methods of image guidance for the treatment of prostate cancer.
- Trial name
- NCT01545154
- Testing
- Transperineal Ultrasound
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- H. James Wallace, MD
Maxillofacial Injuries
Advanced Visuohaptic Surgical Planning for Trauma Surgery
This study proposes to develop a computer-based software tool that will allow surgeons to plan and simulate surgery for patients with jaw trauma.
- Trial name
- NCT01056302
- Testing
- Surgical repair of mandibular fractures
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- VA Office of Research and Development
Blood Loss Anemia, Uterine Atony With Hemorrhage
Oxytocin Dosing at Planned Cesarean Section and Anemia
Patient's with planned cesarean sections will be randomized to receive either standard 20 mU in 1L as a bolus following delivery of the placenta or 20 mu in 1L following delivery of the placenta plus an additional 20 mU in 1L…
- Trial name
- NCT03361124
- Testing
- Oxytocin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Pain, Anesthesia, Regional
Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery
Ethics committee approval was taken on October 22, 2019, numbered 19/342. 120 adult patients who will undergo spine stabilization surgery between October 2019 and January 2020 in "Gülhane Training and Research Hospital" were…
- Conditions
- Postoperative Pain, Anesthesia, Regional, Spinal Stenosis
- Trial name
- NCT04193488
- Testing
- MTP block, ESP block, No Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Maxillary Prognathism, Maxillary Retrusion
Custom Made Plate in Orthognathic Surgery
Orthognathic surgery has traditionally been used to correct dentofacial deformities. Conventional methods rely on 2D radiographic images, occlusal splints, and dental casts, but these approaches have limitations, such as errors…
- Trial name
- OGS (NCT06772688)
- Testing
- orthognathic surgery
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Prostatic Neoplasm
CT/MRI Co-registration Prostate Cancer
The target volume in prostate cancer radiotherapy typically consists of the entire prostate gland which is localized by contours drawn on axial computed tomography (CT) radiation planning images.
- Trial name
- NCT00252460
- Testing
- Computed Tomography Scan and Magnetic Resonance Imaging
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University Health Network, Toronto
Acute Pathology of the Locomotor System
Impact of a Personalized Medication Plan on Duration of Treatment With Potent Opioids in Acute Non-cancer Musculoskeletal Pain.
The aim of this study is to evaluate whether patients who benefit from a personalized pharmaceutical plan (PPP) during their hospitalization, allowing them to be informed and sensitized, are treated for a shorter period of time…
- Trial name
- PPPCARE II (NCT05905146)
- Testing
- personalized pharmaceutical plan
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Anxiety Disorders, Depressive Disorder
Testing Psychosocial Treatment Planning Methods for Youth Anxiety and Depression
Youth depression and anxiety represent a serious public health concern, with affected youth often experiencing social, familial, and academic impairment.
- Trial name
- NCT03610373
- Testing
- Modular Approach to Therapy for Children (MATCH)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Cleft Lip, Congenital Nose Malformation
Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities
There is a robust body of research suggesting that the use of pre-surgical orthopedic devices prior to definitive cleft lip/nose repair results in significant improvement of facial aesthetics with long term follow up.
- Conditions
- Cleft Lip, Congenital Nose Malformation, Deformity, Nose Deformities, Acquired
- Trial name
- NCT04334590
- Testing
- Cleft Lip/Nose Repair without PSIO, Presurgical Infant Orthopedic Therapy
- Where
- United States
- Sponsor
- Johns Hopkins University
Advance Care Planning, Palliative Care
Palliative Care Educator
The investigators propose to conduct a stepped wedge cluster randomized trial of an advance care planning (ACP) educator-led intervention among hospitalized patients aged 65 and over, or any patient with Alzheimer's Disease and…
- Conditions
- Advance Care Planning, Palliative Care, Alzheimer's Disease and Related Dementias, Doctor-patient Communication
- Trial name
- VIDEO-PCE (NCT04857060)
- Testing
- ACP Educator led, video assisted discussion
- Where
- 2 sites in United States
- Volunteers
- 11,174 people
- Sponsor
- Tufts Medical Center
Pneumonia, Pelvic Inflammatory Disease
Drug Use Investigation Of Azithromycin IV For Pneumonia Or Pelvic Inflammatory Disease (Regulatory Post Marketing Commitment Plan)
To collect the efficacy and safety information of Azithromycin IV related to their appropriate use in daily practice
- Trial name
- RESCUE (NCT01671280)
- Testing
- Azithromycin IV
- Volunteers
- 403 people
- Sponsor
- Pfizer
Chronic Periodontitis, Clinical and Microbiological Effects
Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis.
Background: Peridontitis is a group of diseases with complex bacterial etiology that affects a large proportion of the Chilean and worldwide population.
- Trial name
- Metro + Amoxi (NCT01211223)
- Testing
- Administration of Metronidazole plus Amoxicillin
- Where
- Chile
- Volunteers
- 42 people
- Sponsor
- University of Chile
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
3D Specimen Maps for RT Planning
The primary objective of this study is to measure the impact of patient-specific 3D specimen maps on adjuvant radiation treatment volumes and doses to critical organs.
- Conditions
- Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Radiation Therapy
- Trial name
- NCT05743569
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Vanderbilt University Medical Center
Pain, Postoperative, Postoperative Complications
Comparison of Quadratus Lumborum Block and Erector Spina Plane Block in Nephrectomy
Postoperative pain is important due to the limitation of physical functions, delay in recovery of quality of life, long-term opiate use, length of hospital stay, increased care costs and early postoperative pain trigger chronic…
- Trial name
- NCT04459624
- Testing
- Erector Spina Plane Block, Quadratus Lumborum Block 2
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Eskisehir Osmangazi University
Endometrial Cancer
Immunohistochemistry Role in Better Prognosis of Endometrial Carcinoma Patients
The incidence of endometrial cancer (EC) is increasing .Different risk classifications are used to direct the primary and adjuvant therapy.
- Trial name
- NCT06148129
- Testing
- Tissue Biopsy
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Zagazig University
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