Clinical trials: Planning
Esophageal Squamous Cell Carcinoma
Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer
NEEDS is a pragmatic open-label, randomised, controlled, phase III, multicenter trial with non-inferiority design with regard to the first co-primary endpoint overall survival and superiority for the experimental intervention…
- Trial name
- NEEDS (NCT04460352)
- Testing
- Neoadjuvant radiotherapy (arm A), Carboplatin, paclitaxel, Esophagectomy
- Where
- 12 sites in Canada, Ireland and 3 more
- Volunteers
- 1,020 people
- Sponsor
- Karolinska University Hospital
Total Knee Anthroplasty, Total Knee Arthroplasty Recovery
The Effects of Mir Shakeel Teleintegrated Therapy Plan in Patients Undergoing Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effectiveness of a newly developed Modified Structured Telerehabilitation Intervention Protocol (MSTITP) compared with conventional in-person physical therapy in patients…
- Trial name
- RCT (NCT07239258)
- Testing
- Mir Shakeel Teleintegrated Therapy plan, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Lincoln University College Malaysia
Prostate Cancer
Multifunctional Magnetic Resonance (MR) for Radiotherapy Planning in Prostate Cancer
To determine if functional MRI methods will aid planning of a radiation dose boost within the prostate in patients with prostate cancer potentially improving safety and efficacy.
- Trial name
- NCT01006564
- Testing
- Imaging Investigations (not radiation), Other
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Advanced Refractory Left Ventricular Heart Failure
HeartMate 3™ CE Mark Clinical Investigation Plan
The purpose of this clinical investigation is to evaluate the performance and safety of the HeartMate 3 Left Ventricular Assist System (HM3 LVAS) To support obtaining CE Mark for the HM3 LVAS in Europe, a multi-center clinical…
- Trial name
- HM3 CE Mark (NCT02170363)
- Testing
- Left Ventricular Assist System (LVAS)
- Where
- 10 sites in Australia, Austria and 4 more
- Volunteers
- 50 people
- Sponsor
- Abbott Medical Devices
Obesity, Adolescent, Menstrual Problem
Evaluation of the Effects of Planned Trainings Given to Obese Adolescent Girls on Healthy Lifestyle Behaviors and Menstrual Symptoms
The aim of this study is to evaluate the effects of training given to obese female students in mid-adolescence period for improving nutrition, physical activity, and menstrual symptoms on the improvement of their healthy…
- Conditions
- Obesity, Adolescent, Menstrual Problem, Health Behavior
- Trial name
- NuFaMeSTra (NCT04044833)
- Testing
- Health life style behaviour ,
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hulya Erbaba
Malignant Pleural Effusion, Stage IIIB Non-small Cell Lung Cancer
FDG-Labeled PET Scan in Planning Chemotherapy in Treating Patients With Stage IIIB or IV Non-Small Cell Lung Cancer
This phase II trial studies how well fludeoxyglucose F 18 (FDG)-labeled positron emission tomography (PET) scan works in planning chemotherapy in treating patients with stage IIIB or IV non-small cell lung cancer (NSCLC).
- Conditions
- Malignant Pleural Effusion, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
- Trial name
- NCT00564733
- Testing
- carboplatin, docetaxel, gemcitabine hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Washington
Constipation - Functional
Adherence/Outcomes After Use of Constipation Action Plan
Adherence to recommendations for treatment of chronic constipation in pediatric population is often poor. This study is attempting to improve adherence, and outcomes, by implementing a trial of a constipation action plan plus…
- Trial name
- NCT03821532
- Testing
- Constipation Action Plan
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Disabilities Physical, Disabilities Mental
Feasibility and Effectiveness of a Coordinated Healthcare Circuit Dedicated to Patients With Handicap
France currently has more than 10 million disabled people, including 3 millions who could be better treated. In fact, people with disabilities face many obstacles in accessing care and receiving appropriate support (physical…
- Trial name
- INFRA (NCT04991558)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Groupe Hospitalier Mutualiste de Grenoble
HIV Infection, HIV Infections
Integration of Family Planning and HIV Services in Tanzania
HIV positive women and couples have broad reproductive health needs that are not always met within HIV services. The integration of family planning (FP) services into Tanzania's HIV Care and Treatment Clinics (CTC) will address…
- Trial name
- NCT00941876
- Testing
- Facilitated Referral
- Where
- Tanzania
- Volunteers
- 864 people
- Sponsor
- FHI 360
Dietary Exposure
Feasibility of Low Energy Diet in HFpEF and Type 2 Diabetes
Open, Single arm intervention, feasibility study
- Trial name
- ALLEVIATE (NCT04173117)
- Testing
- Low energy meal replacement plan (12 weeks)
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- University of Leicester
Suicide
Rapid Personalization of Safety Plans for Psychiatrically Hospitalized Veterans at High-Risk for Suicide
Veterans psychiatrically hospitalized face significantly elevated suicide risk, particularly in the three months post-discharge.
- Trial name
- NCT07507786
- Testing
- Personalized Safety Plans, Safety Plans as Usual + Calls
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- VA Office of Research and Development
Antenatal Corticosteroids
Effect of Antenatal Corticosteroids on Neonatal Hypoglycemia
Comparing the incidence of neonatal hypoglycemia in infants born to mothers who received antenatal corticosteroids to those who did not.
- Trial name
- NCT06716918
- Testing
- Corticosteroid Injection
- Where
- Egypt
- Volunteers
- 188 people
- Sponsor
- Assiut University
Domestic Violence
Internet-Based Intervention to Improve Mental Health Outcomes for Abused Women
The purpose for this trial is to test the effectiveness of the first interactive internet-based safety decision aid on abused women's exposure to repeat intimate partner violence (IPV) and mental health outcomes.
- Trial name
- NCT01312103
- Testing
- Internet-based safety decision aid, Usual Care Safety Plan
- Where
- 4 sites in United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hepatocarcinoma
Benefit of the Use of 3D Models and Tools in Hepatectomy Planning for Hepatocarcinomas
The aim of this study is to assess the benefit of 3D models in the planning of hepatic resection by comparing the changes in the surgical plan based on the analysis of conventional preoperative images (CT-scan and MRI), compared…
- Trial name
- 3D-HAPPI (NCT03382327)
- Testing
- Surgical planning
- Where
- 12 sites in France
- Volunteers
- 136 people
- Sponsor
- IHU Strasbourg
Cervical Cancer
Image Based Brachytherapy in Locally Advanced Cervical Cancers - a Randomized Controlled Trial
Purpose of the study is to determine whether Image based brachytherapy is superior in terms of local control to Conventional radiograph based brachytherapy in locally advanced cervical cancers in a Phase III randomized setting.
- Trial name
- COMBAT-Cx (NCT03005743)
- Testing
- Magnetic Resonance Image based Brachytherapy, Conventional Radiograph based Brachytherapy
- Where
- India
- Volunteers
- 1,050 people
- Sponsor
- Tata Memorial Hospital
Brain Neoplasms, Brain Cancer
Optimal Planning Target Volume With Stereotactic Radiosurgery
The purpose of this study is to estimate the rate of local control at the treated site of the metastasis as a function of 1mm versus 3mm expansion about the gross tumor volume (GTV).
- Trial name
- NCT01017497
- Testing
- Stereotactic Radiosurgery
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Duke University
Recurrent Prostate Carcinoma
Multicenter Randomized Trial of 68Ga-PSMA-11 PET/CT Based SRT After Radical Prostatectomy
This phase III trial studies how well Gallium Ga 68-labeled PSMA-11 (68Ga-PSMA-11) positron emission tomography (PET)/computed tomography (CT) works in diagnosing participants with prostate cancer that has come back after…
- Trial name
- PSMA SRT (NCT03582774)
- Testing
- Best Practice, Computed Tomography, Gallium Ga 68-labeled PSMA-11
- Where
- 2 sites in United States
- Volunteers
- 193 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Alcohol-Related Disorders, Substance-Related Disorders
Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years
The goal of this clinical trial is to test the effectiveness of evidence-based Screening, Brief Intervention, and Referral to Treatment (SBIRT) among adult patients who screen positive to one or more risky alcohol or substance…
- Conditions
- Alcohol-Related Disorders, Substance-Related Disorders, Mental Health, Reproductive Health
- Trial name
- NCT05910580
- Testing
- Screening, Brief Intervention, and Referral to Treatment (SBIRT)
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Mental Health Care, Sexual Health Quality of Life
Self-efficacy and Knowledge (SEEK) Trial to Improve Sexual Reproductive Health and Well-being for Syrian Refugee Women and Girls in Lebanon
This community-based randomized controlled trial (RCT) aims to evaluate a low-resource/low-intensity integrated sexual reproductive health (SRH) and wellbeing intervention package.
- Conditions
- Mental Health Care, Sexual Health Quality of Life, Family Planning Services
- Trial name
- SEEK (NCT07008950)
- Testing
- The Self-Efficacy and Knowledge Trial
- Where
- Lebanon
- Volunteers
- 485 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Executive Dysfunction, Attention Deficit Hyperactivity Disorder
HOPS Study: A Conceptual Replication
The purpose of this current study is to conduct a conceptual replication with an independent evaluation team of the randomized controlled trial conducted by Langberg and colleagues, which demonstrated the efficacy of the…
- Trial name
- NCT04465708
- Testing
- Homework, Organization, and Planning Skills
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
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