Clinical trials: Planning
Contraception Behavior
A Pilot Study to Estimate the Impact of a Screening and Referral Service on Contraceptive Use
The specific aim of this pilot study is to estimate the impact of a new digital health service on the uptake of family planning among Kenyan women with an unmet need for contraception.
- Trial name
- E0108 (NCT03224390)
- Testing
- digital family planning screening and referral service
- Where
- Kenya
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Duke University
Lung Carcinoma, Malignant Neoplasm
SPECT/CT in Measuring Lung Function in Patients With Cancer Undergoing Radiation Therapy
This pilot clinical trial studies single photon emission computed tomography (SPECT)/computed tomography (CT) in measuring lung function in patients with cancer undergoing radiation therapy.
- Trial name
- NCT01982123
- Testing
- SPECT/CT, Single Photon Emission Computed Tomography, Technetium Tc-99m Albumin Aggregated
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Washington
Grief
Experiencing Loss and Planning Ahead Study
The course of dementia over many years, gradual losses and uncertain life expectancy can lead to grief amongst family and friend carers.
- Trial name
- ELPAS (NCT03332979)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University College, London
Smoking Cessation
Drug Use Investigation Of Varenicline (Regulatory Post Marketing Commitment Plan)
The objective of this surveillance is to collect information about 1) adverse drug reaction not expected from the LPD (unknown adverse drug reaction), 2) the incidence of adverse drug reactions in this surveillance, and 3)factors…
- Trial name
- NCT00772941
- Testing
- Varenicline
- Volunteers
- 3,939 people
- Sponsor
- Pfizer
Percutaneous CFA Arteriotomy Closure
Safety and Performance Study of Large Hole Vascular Closure Device FIV
The purpose of this Clinical Investigation Plan (CIP) is to: 1. Confirm the safety and performance of the PerQseal® large hole closure system. 2.
- Trial name
- Frontier-IV (NCT03423602)
- Testing
- PerQseal®
- Where
- 11 sites in Germany, Ireland
- Volunteers
- 75 people
- Sponsor
- Vivasure Medical Limited
Coronary Artery Disease
Trial in Subjects Undergoing Cardiac Catheterization With Planned Percutaneous Coronary Intervention With Stenting
The purpose of this study is to provide information of the relative potency of prasugrel and clopidogrel on platelet function studies, inflammation, and myocyte necrosis in subjects undergoing elective percutaneous coronary…
- Trial name
- PRINCIPLE (NCT00357968)
- Testing
- Prasugrel, Clopidogrel
- Where
- 16 sites in United States, France and 2 more
- Volunteers
- 201 people
- Sponsor
- Eli Lilly and Company
Social Stigma, Substance Use Disorders
Planning a Multi-Level Intervention to Reduce Substance Use Stigma in HIV Prevention and Care
This is a community-engaged research project that aims to identify and pilot test interventions that may reduce substance use stigma among professionals at primary care sites serving patients who might be exposed to HIV or are…
- Conditions
- Social Stigma, Substance Use Disorders, HIV Infections, Physician-Patient Relations
- Trial name
- NCT05925374
- Testing
- Substance use stigma training
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Leukemia, Lymphoma
Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT)
The goal of this clinical research study is to learn what dose of a kind of immune cell called T-lymphocytes (T-cells) given as a donor infusion about 8-9 weeks after a stem cell transplant has the best results.
- Conditions
- Leukemia, Lymphoma, Myeloma, Myeloproliferative Diseases
- Trial name
- NCT01518153
- Testing
- Fludarabine, Melphalan, Alemtuzumab
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- M.D. Anderson Cancer Center
Arthritis
Real Time 3D Imaging and Surrogate Bone Model
This is an observer-blinded prospective randomized clinical trial to define the efficacy of a new technology developed at the Cleveland Clinic to improve the positioning of the acetabular shell in total hip arthroplasty.The…
- Trial name
- NCT02204007
- Testing
- 3D imaging & surrogate bone model
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Suicide
Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT
The management of suicide risk is a pressing national public health issue especially among Veterans. This grant consists of two arms: the novel treatment and treatment-as-usual.
- Trial name
- PLF (NCT03653637)
- Testing
- Project Life Force, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- VA Office of Research and Development
Type 2 Diabetes
Complete Health Improvement Program for Geisinger Health Plan Members With Type 2 Diabetes
The Complete Health Improvement Program (CHIP) is a lifestyle improvement program intended to prevent and/or manage cardiovascular disease, diabetes, and other health conditions.
- Trial name
- CHIP-RCT (NCT04924400)
- Testing
- CHIP Program, Usual Care
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Thomas Morland
Non Small Cell Lung Cancer
Dosage Schedule Study of Pemetrexed Monochemotherapy for Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Patients affected by non-small cell lung cancer (NSCLC) will be treated in pemetrexed monochemotherapy regimen for a maximum of 8 cycles.
- Trial name
- NCT00370292
- Testing
- Pemetrexed - Before Protocol Amendment, Pemetrexed - After Protocol Amendment
- Where
- Italy
- Volunteers
- 19 people
- Sponsor
- Eli Lilly and Company
Epilepsy
Clinical and Economic Burden of Uncontrolled Epilepsy: Analyses From a Medicaid Database and a Private Health Plan Database
Antiepileptic drugs (AEDs) are the main therapeutic option for patients with epilepsy; however, complete seizure control remains elusive for many patients.
- Trial name
- NCT01390909
- Testing
- Anti-epileptic drug (AED)
- Volunteers
- 12,386 people
- Sponsor
- GlaxoSmithKline
Heart Failure, Pulmonary Disease, Chronic Obstructive
Advancing Symptom Alleviation With Palliative Treatment
Chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), and interstitial lung disease (i.e., pulmonary fibrosis) are common serious illnesses.
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Emphysema, Pulmonary Fibrosis, Interstitial Lung Disease
- Trial name
- ADAPT (NCT02713347)
- Testing
- ADAPT Intervention
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- VA Office of Research and Development
Colorectal Cancer Metastatic, Colorectal Cancer
TheraSphere® For Treatment of Metastases in Liver
To investigate whether the dose predicted by pre-therapy 99mTc MAA SPECT predicts the dose to the liver from the 90Y microspheres as assessed by post-therapy 90Y SPECT/CT or positron emission tomography (PET)/CT.
- Trial name
- NCT04517643
- Testing
- Therasphere Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Advance Care Planning, Palliative Care
Palliative Care for Persons With ADRD and CI in SNF
Alzheimer's disease and related dementias (ADRD) are serious, life limiting illnesses with no known cure. Dementia is the fifth-leading cause of death in older adults and the majority of people with advanced dementia die in…
- Conditions
- Advance Care Planning, Palliative Care, Skilled Nursing Facility, Cognitive Impairment
- Trial name
- NCT05308004
- Testing
- Palliative Care Consultation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Maryland, Baltimore
Neoplasms
Evaluating the Impact of Patient-Centered Oncology Care
The National Committee for Quality Assurance has worked with the National Coalition for Cancer Survivorship, the American Society of Clinical Oncology, Oncology Management Services, Independence Blue Cross, and RAND, as well as a…
- Trial name
- NCT02110758
- Testing
- Pilot of Patient-Centered Oncology Care
- Where
- United States
- Volunteers
- 125,250 people
- Sponsor
- National Committee for Quality Assurance
Palliative Care, Advance Care Planning
Palliative Care Consultations in the Skilled Nursing Facility (SNF) Setting
Close to one-third of Medicare decedents use the Medicare skilled nursing facility (SNF) benefit in the 6 months prior to death.
- Conditions
- Palliative Care, Advance Care Planning, Skilled Nursing Facilities
- Trial name
- NCT03958552
- Testing
- Palliative Care Consultation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Maryland, Baltimore
Asthma
Coordinated Healthcare Interventions for Childhood Asthma Gaps in Outcomes
Chicago is an epicenter for asthma health disparities in the U.S., with African-American children 5-11 yrs bearing a disproportionate share of the burden.
- Trial name
- CHICAGO (NCT02319967)
- Testing
- CAPE, CHW home visits
- Where
- 6 sites in United States
- Volunteers
- 373 people
- Sponsor
- University of Illinois Chicago
Pain Associated With Fibromyalgia
Special Investigation of Pregabalin for Fibromyalgia (Regulatory Post Marketing Commitment Plan)
To collect the efficacy and safety information of Pregabalin on Fibromyalgia patients related to their appropriate use in daily practice.
- Trial name
- NCT01773993
- Testing
- Pregabalin
- Volunteers
- 534 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.