Clinical trials: Plaque Accumulation
Dental Biofilm Accumulation
RCT: Enzyme Blend Toothpaste on Dental Biofilm Plaque Accumulation
The aim of the study is to investigate whether brushing twice a day with a toothpaste (Biofresh Clean) containing a blend of alpha-amylase and gluco-amylase improves oral health outcomes over a 14-day period.
- Trial name
- NCT07079683
- Testing
- Toothpaste Product
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Gingivitis, Periodontitis
Efficacy of Essential Oil Mouthwash With and Without Alcohol: a 3-Day Plaque Accumulation Model
The daily removal of supragingival dental plaque is a major factor in the prevention of caries, gingivitis and periodontitis. Proper control of bacterial plaque is obtained through the mechanical removal of the biofilm by the…
- Trial name
- NCT01411618
- Testing
- free alcohol essential oil mouthwash
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Gingivitis, Plaque
ToothWave Calculus Reduction and Accumulation Prevention Study
The objective of the study is to evaluate the safety and efficacy of the home-use device ToothWave (Model H7001) for calculus reduction and the prevention of calculus accumulation.
- Conditions
- Gingivitis, Plaque, Calculus, Dental
- Trial name
- NCT04596761
- Testing
- RF-utilizing powered toothbrush
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Dental Plaque Accumulation, Oral Hygiene Education Methods
Evaluation of a Novel Dual-Headed Toothbrush Design for Periodontal Health: Split-Mouth Randomized Blind Clinical Trial
The goal of this clinical trial is to evaluate the effectiveness and patient satisfaction of a novel dual-headed toothbrush design compared to a conventional single-headed toothbrush in adult dental professionals aged 22-45 years…
- Conditions
- Dental Plaque Accumulation, Oral Hygiene Education Methods, Toothbrushing
- Trial name
- NCT07030088
- Testing
- Dual-Headed Manual Toothbrush, Conventional Single-Headed Manual Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Dar Al Uloom University
Plaque Accumulation, Gingival Inflammation
Triphila Mouthwash Effect as Anti-plaque and Anti-gingivitis in Children
The study aim to to assess the antiplaque and antigingivitis efficacy of Triphala mouthwash versus chlorhexidine mouthwash among children.
- Trial name
- NCT07016659
- Testing
- 0.12% Chlorhexidine Mouthwash ( Hexitol ), Triphila mouthwash
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Gingivitis
Comparisons of Efficacy of Triphala and Chlorhexidine Mouthwash Against Plaque Accumulation and Gingivitis.
Gingivitis is one of the commonly prevalent oral diseases worldwide which is caused by the bacterial biofilm adhering to the teeth surfaces. Chlorhexidine is the antimicrobial agent most familiar to dental professionals.
- Trial name
- NCT07426393
- Testing
- 6% Triphala mouthwash, .2% chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 220 people
- Sponsor
- Bangladesh Medical University
Gingivitis, Plaque Accumulation
Evaluation Study of a Mouthwash Based on Schinus Terebinthifolius to Treat Gingivitis in Children
The purpose of this study is to evaluate the clinical efficacy of a mouthwash based on a natural product (Schinus terebinthifolius) used by children with gingivitis.
- Trial name
- NCT01197105
- Testing
- Use of natural product (Schinus terebinthifolius)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Gingivitis, Dental Plaque Accumulation
6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health
The goal of this clinical trial is to evaluate the clinical efficacy of an antimicrobial mouthrinse, with a particular focus on its effect on established plaque and the improvement of gum health.
- Trial name
- NCT07414173
- Testing
- Test Mouthrinse, Control Mouthrinse
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Dental Plaque
Pooled Analysis of Clinical Data From Six GSK Studies to Investigate the Efficacy of a Dentifrice Containing 67% Weight by Weight (w/w) Sodium Bicarbonate on Gingivitis and Plaque Accumulation
The aim of this analysis was to pool data from 6 GSK studies with similar clinical design to investigate the overall efficacy of a test dentifrice containing 67% w/w sodium bicarbonate in the treatment of gingivitis and plaque…
- Trial name
- NCT03703245
- Testing
- Sodium bicarbonate, Control Dentifrice
- Where
- United Kingdom
- Volunteers
- 1,601 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Plaque-Induced Gingivitis, Dental Plaque Accumulation
Innovative Mouthwash in School-Aged Children With Fixed Orthodontic Appliances
Fixed metal orthodontic appliances create additional plaque-retentive areas around brackets, archwires and ligatures, making mechanical plaque control more difficult in children and adolescents.
- Conditions
- Plaque-Induced Gingivitis, Dental Plaque Accumulation, Halitosis
- Trial name
- NCT07710144
- Testing
- Test mouthwash, Chlorhexidine-containing mouthwash
- Where
- Bulgaria
- Volunteers
- 90 people
- Sponsor
- Plovdiv Medical University
Dental Plaque, Gingivitis
Effect of an Enzyme-containing Lozenge on Dental Biofilm in Healthy Individuals.
The purpose of the study is to assess the effect of an enzyme containing lozenge on dental plaque accumulation in healthy adults.
- Conditions
- Dental Plaque, Gingivitis, Microbial Colonization
- Trial name
- NCT05070507
- Testing
- Enzyme containing lozenge
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Gingival Inflammation, Dental Plaque Accumulation
Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash).
- Trial name
- NCT07824388
- Testing
- Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Complication of Personal Oral Hygiene
The Use of Quantitative Light Induced Fluorescence Digital as an Oral Hygiene Evaluation Tool in Orthodontics
During orthodontic treatment bacterial plaque readily accumulates on the teeth. This is because food easily accumulates around the braces and it is more difficult to clean when the braces are in place.
- Trial name
- NCT02545660
- Testing
- QLF Image, White Light Image
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Gingivitis, Periodontitis
A Clinical and Imaging Study to Evaluate a Novel Dentifrice
There is a need for toothpastes that more effectively remove oral biofilm, inhibit biofilm re-formation and support periodontal health.
- Conditions
- Gingivitis, Periodontitis, Dental Plaque
- Trial name
- NCT02271815
- Testing
- Oral Hygiene
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of California, Irvine
Dental Plaque, Dental Plaque Accumulation
Effect of Different Products to Support Plaque Control During Daytime
The goal of this clinical trial is to test if the additional use of different commercially available products for a better breath and plaque reduction, taken during daytime between morning and evening tooth brushing, can reduce…
- Conditions
- Dental Plaque, Dental Plaque Accumulation, Mouthwashes, Chewing Gum
- Trial name
- NCT07382310
- Testing
- Oral B Pro-Health Multi-Protection Mouth Rinse refreshing mint without alcohol (0.07% CPC), Listerine Total Care mouth rinse without alcohol, Colgate total advanced pro-shield mouth rinse without alcohol (0.075% CPC)
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Plaque Accumulation, Patient Acceptance
The Effect of Stingless Bee Honey Mouthrinse on Dental Plaque Accumulation
Mouthrinses are recommended as a complement to mechanical methods in oral hygiene procedures to prevent and control periodontal diseases. Chlorhexidine mouthrinse has been used as a chemical plaque control agent for many years.
- Trial name
- NCT06223243
- Testing
- Stingless bee honey mouthrinse, normal saline mouthrinse, chlorhexidine mouthrinse
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Islam Malaysia
Dental Caries, Dental Plaque Accumulation
Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal
The study investigates the effectiveness of a 45°-cut miswak for plaque removal compared to a toothbrush in children and assesses their preferences for these tools.
- Trial name
- NCT07409610
- Testing
- Miswak, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Gingival Bleeding, Dental Plaque Accumulation
Adjunctive Oral Hygiene Aids in Reducing Oral Hygiene Parameters Among Orthodontic Patients
Adult orthodontic patients aged 18-30 were included in a randomised, singleblind clinical research using a split-mouth design at a dental clinic.
- Trial name
- D-F-H-17-Dec (NCT06779279)
- Testing
- Water flosser and super flosser, Orthodontic brush
- Where
- United Arab Emirates
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- sudhir rama varma