Clinical trials: Plaque Induced Gingival Disease
Gingivitis
Frankincense and Herbal Extracts for Plaque-Induced Gingivitis: A Double-Blind RCT
Frankincense, a natural resin obtained from trees of the Boswellia genus, has been traditionally used for its medicinal properties.
- Trial name
- FHEPIG (NCT07535229)
- Testing
- Frankinscence and coconut Oil based mouthwash, Frankinscence and Thyme essence/ water based mouthwash, Chlorhexidine (0.2%)
- Where
- Oman
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Oman Dental College
Gingivitis and Periodontal Diseases, Dental Plaque
0.2% Chlorhexidine vs MicroRepair ABX in Gingivitis
Gingivitis is the most common form of reversible gum disease, caused by the accumulation of dental plaque. It leads to inflammation of the gums, bleeding, and discomfort, but it can be managed and reversed with professional…
- Conditions
- Gingivitis and Periodontal Diseases, Dental Plaque, Oral Hygiene
- Trial name
- GEM-CHX02 (NCT07088666)
- Testing
- MicroRepair ABX mouthwash, Chlorhexidine 0.2% mouthwash
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Gingivitis, Dental Plaque
MicroRepair® ABX vs Chlorhexidine 0.12% in Gingivitis Patients
This randomized controlled clinical trial is designed to compare the adjunctive effects of two mouthwashes used after professional biofilm removal in patients with generalized plaque-induced gingivitis, a reversible inflammatory…
- Conditions
- Gingivitis, Dental Plaque, Gingival Inflammation
- Trial name
- GEM-CHX012 (NCT07088653)
- Testing
- MicroRepair ABX mouthwash, Chlorhexidine 0.12% mouthwash
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Plaque-Induced Gingivitis
Individualized Management of Plaque-Related Gingival Inflammation in Routine Dental Practice
Gingival inflammation is common and can often be reversed with effective daily oral hygiene. However, preventive care is not always delivered consistently in dental practices, and patients may not receive sufficient…
- Trial name
- NCT07882459
- Testing
- Structured Preventive Care Workflow (iMGi)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Curaden AG
Plaque-Induced Gingivitis, Orthodontic Treatment
Clinical Outcomes of Different Mouth Rinses During Clear Aligner Orthodontic Therapy
This pilot randomized controlled clinical trial will evaluate the feasibility and preliminary clinical effects of three mouth rinses-alum, Triphala-based herbal mouth rinse, and 0.2% chlorhexidine-in adults undergoing clear…
- Trial name
- NCT07865416
- Testing
- Alum Mouth Rinse, Triphala-based Herbal Mouth Rinse, Chlorhexidine mouth rinse
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Manav Rachna International Institute of Research and Studies
Gingivitis
Efficacy of an Amine and Zinc Lactate - Containing Mouthrinse in the Home-based Treatment of Plaque-induced Gingivitis in Adolescents.
The goal of this clinical trial is to evaluate if the adjunctive use of an amine and zinc lactate - containing mouthrinse may give significant benefits in the home-based treatment of plaque-induced gingivitis in adolescents.
- Trial name
- SPA (NCT06671106)
- Testing
- toothbrushing, flossing, Toothpaste Product
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Università degli Studi di Ferrara
Gingivitis; Chronic, Oxidative Stress
Efficacy of Green and White Tea Extract Mouthwashes in the Management of Plaque-induced Gingivitis: A Clinical and Biochemical Study
Background and objective: Tea is the second most consumed drink in the world after water. Gingivitis is among the most common infectious diseases.
- Conditions
- Gingivitis; Chronic, Oxidative Stress, Inflammation
- Trial name
- NCT05861206
- Testing
- GT-MW group (5% Green tea), WT-MW group (5% White tea),EO-MW group (Listerine mouthrinse), CHX-MW group (0.12% CHX, as a positive control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Yağmur Saraç Gül
Plaque, Dental, Dental Plaque Induced Gingivitis
The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients
This randomized controlled trial will be conducted on 40 orthodontic patients at the Department of Orthodontics, University Hospital Centre Zagreb, Croatia. Respondents will be randomly allocated into 4 groups (n=10).
- Conditions
- Plaque, Dental, Dental Plaque Induced Gingivitis, White Spot Lesion
- Trial name
- NCT06331442
- Testing
- Photodynamic therapy, Tricalcium phosphate (TCP) varnish with 5% NaF, Chlorhexidine varnish
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Plaque Induced Gingivitis, Mouth Diseases
Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide
The goal of this clinical trial is to test efficiency of using mouth rinse containing (H2O2 and HA) over a period of two weeks to control on gingival inflammation and plaque accumulation through measuring the clinical periodontal…
- Conditions
- Plaque Induced Gingivitis, Mouth Diseases, Bleeding Gum, Periodontal Diseases
- Trial name
- NCT05787600
- Testing
- Perhyal rinse, Chlorhexidine mouthwash
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontal Diseases, Periodontitis and Treatment Need
Micro-Needling Technique Using Ozonated Olive Oil in Periodontal Diseases
The research idea is based on using micro-acupuncture therapy with ozone-treated olive oil to improve the condition of patients suffering from gingivitis and periodontitis and comparing it to the scientifically proven…
- Conditions
- Periodontal Diseases, Periodontitis and Treatment Need, Gingivitis
- Trial name
- NCT06990282
- Testing
- microneedling, scaling, Ozonated olive oil
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Fayoum University
Gingival Bleeding, Von Willebrand Diseases
Gingival Bleeding and Von Willebrand Disease Typ 2 and 3
Von Willebrand disease (VWD) is the most common inherent bleeding disorder resulting in prolonged bleeding time. Gingival bleeding is a frequently reported symptom of VWD.
- Trial name
- NCT03078595
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Goethe University
Gingival and Periodontal Disease
Anti-microbial Effect of Acacia Arabica Extract on Gingival and Periodontal Health of Dental Patients
This randomized clinical pilot study evaluated the short-term effects of Acacia arabica mouth rinse and paste as adjuncts to conventional oral hygiene in adults with plaque-induced gingivitis.
- Trial name
- NCT07840131
- Testing
- Acacia arabica Mouth Rinse, acacia arabica paste
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- Umm Al-Qura University
Gingivitis
Efficacy Of Lotus Leaves In Management Of Plaque Induced Gingivitis
Due to difficulties in maintenance of an effective mechanical oral hygiene regime, effective chemical adjunctive measures will likely significantly contribute to overall oral health, the function of which should be to augment…
- Trial name
- NCT01956656
- Testing
- lotus leaf mouthwash
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sri Hasanamba Dental College and Hospital
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Plaque Induced Gingivitis
Plaque and Gingivitis Evaluation of a U-Shaped Toothbrush in a 30-Day Model
The objective of this 30 day, randomized, two group, parallel, examiner-blind clinical trial is to assess the safety and efficacy of AutoBrush® 360° U-shaped Sonic Toothbrush on plaque and gingivitis, compared to an American…
- Trial name
- NCT06122376
- Testing
- U-shaped Power Toothbrush, Soft Manual Toothbrush
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Lander Enterprises, LLC
Gingivitis, Mouth Diseases
Clinical Effects of Tooth Powder on Gingivitis
Dental plaque, known as dental biofilm, is implicated as the primary etiological agent responsible for oral inflammatory diseases.
- Trial name
- Toothpowder (NCT01902095)
- Testing
- Tooth powder, Tooth paste (control)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Dental Plaque, Dental Plaque Induced Gingivitis
Clinical Efficacy of the Combined Effect of Oral Irrigator and Chemicals (0.075% CPC)
This is an experimental gingivitis clinical study to evaluate gum health efficacy from the combination effect of water flosser and chemistry (0.075% CPC) compared to water flosser and water and to no oral hygiene regimen with a…
- Conditions
- Dental Plaque, Dental Plaque Induced Gingivitis, Dental Plaque and Gingivitis, Gingivitis
- Trial name
- WFPOC (NCT06607172)
- Testing
- oral irrigator, Cetylpyridinium Chloride (CPC)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque-Induced Gingivitis
Efficacy of Thymus Vulgaris Mouthwash in the Management of Biofilm-Induced Gingivitis
The goal of this clinical trial is to learn whether a mouthwash made from thyme (Thymus vulgaris in its scientific name) helps improve gum health in people with plaque-induced gingivitis.
- Trial name
- NCT07905456
- Testing
- Thymus vulgaris mouthwash, Chlorhexidine 0,12%
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Sulaimani
Gingival Bleeding, Plaque Induced Gingival Disease
Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis Reduction
Clinical study evaluating the effectiveness of an alcohol-free mouthwash containing CPC+Zn compared to dental flossing and an essential oils-containing alcohol mouthwash in reducing dental plaque and gingivitis.
- Conditions
- Gingival Bleeding, Plaque Induced Gingival Disease, Gingivitis and Periodontal Diseases
- Trial name
- PGMWI (NCT06607263)
- Testing
- Mouthwash CPC+Zn+F, Essential oils mouthrinse, Dental floss
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Colgate Palmolive
Plaque-Induced Gingivitis
Impact of Oral Hygiene Instruction in Gingivitis Patients
The aim of this study is to comparatively evaluate the effectiveness of two different oral hygiene instruction methods given in addition to Phase 1 periodontal treatment in patients diagnosed with gingivitis, on periodontal…
- Trial name
- NCT07479706
- Testing
- video-based oral hygiene instruction, Model-based oral hygiene instruction
- Where
- Turkey (Türkiye)
- Sponsor
- Ankara University