Clinical trials: Plastic Surgery, open to volunteers
Drain Output After Breast Reduction Surgery, Breast Reductions
Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery
This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery.
- Trial name
- NCT07131592
- Testing
- IV TXA, Topical TXA, Topical saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Cleft Lip, Cleft Lip Scar
Cleft Lip Scarring After Botox
This study is investigating whether botulinum toxin type A (Botox) can improve scar appearance after cleft lip repair surgery. Cleft lip repair is commonly performed during infancy, but visible scarring can occur as the incision…
- Trial name
- CLSAB (NCT07880860)
- Testing
- Botulinum Toxin Type A (BOTOX) Injection, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's National Research Institute
Pain, Genetic Change
COMT and OPRM1 Polymorphisms and Their Effect on Post-Operative Pain in Children
The goal of this observational study is to investigate whether the A118G single-nucleotide polymorphism (SNP) in the mu-opioid receptor1(OPRM1) and Catechol-O-methyltransferase (COMT) SNPs influence postoperative pain scores in…
- Conditions
- Pain, Genetic Change, Children, Only
- Trial name
- NCT06777875
- Where
- Lebanon
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Breast Reconstruction, Breast Cancer
Optimizing Postoperative Recovery After Breast Reconstruction With Autologous Tissue (BestDIEP)
Women who have their breast reconstructed with autologous tissue seem to be more satisfied with their breast. However, autologous breast reconstruction entails a bigger operation, and the usage of more health care resources, than…
- Trial name
- BestDIEP (NCT05363189)
- Testing
- Venous augmentation, Traditional ERAS (enhanced recovery after surgery) protocol, Sahlgrenska recovery protocol
- Where
- Sweden
- Volunteers
- 380 people
- Sponsor
- Vastra Gotaland Region
Breast-conserving Plastic Surgery, Granulomatous Mastitis
Effect of Different Surgical Approaches of Granulomatous Mastitis
The objective of this study was to prospectively investigate the effects of different surgical approaches on the recurrence rate and aesthetic outcome of patients with granulomatous mastitis.
- Trial name
- NCT06712524
- Testing
- Breast-conserving plastic surgery, Traditional breast surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Hubei Cancer Hospital
Reconstructive Surgical Procedures, Plastic Surgery
Leica Microsystems Sponsored Study to Collect and Confirm Clinical Data on the Performance of the GLOW800 Device When Used in Accordance With Its Intended Use.
This post-market clinical follow-up (PMCF) study aims to confirm the safety and performance of the GLOW800 surgical microscope accessory when used in conjunction with the ARveo8x surgical microscope.
- Conditions
- Reconstructive Surgical Procedures, Plastic Surgery, Vascular Surgical Procedure, Cerebrovascular Disorder
- Trial name
- IMED-GLOW800 (NCT07164040)
- Testing
- The GLOW800, a non-contact, non-invasive device, allows the surgical microscope ARveo 8 and ARveo 8X to produce excitation light and resolve fluorescence emission from the fluorescent agent ICG
- Where
- 3 sites in Portugal, Spain and 1 more
- Volunteers
- 31 people
- Sponsor
- Leica Microsystems (Schweiz) AG
Abdominoplasty, Panniculectomy
Patient Satisfaction and Reflection on Drain Placement
The purpose of this research study is to evaluate the ideal drain placement in patients undergoing abdominoplasty or panniculectomy.
- Trial name
- NCT06043557
- Testing
- Drain Placement
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Plastic Surgery Procedures
Safety and Feasibility of the MACS in Surgical Procedures: A Prospective Multi-Center Study
The goal of this clinical trial is to evaluate the safety and performance of the MACS device in adults undergoing elective plastic surgery procedures.
- Trial name
- NCT07470411
- Testing
- MACS System
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Levita Magnetics
Postoperative Facial Ecchymosis, Postoperative Facial Edema
Perioperative Photobiomodulation in Facial Plastic Surgery
This study is testing whether a new light therapy schedule can reduce bruising after facial plastic surgery, compared with the light therapy schedule currently used in the investigator's practice.
- Trial name
- CLEAR PBM (NCT07846631)
- Testing
- ELIXIR MD Photobiomodulation (PBM) System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Elixir MD Inc
Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate
Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Maxilla.
Multiple techniques can be used for recession coverage. The most common techniques are: tunnel technique (T), coronally advanced flap (CAF) or a combination of both (TCAF).
- Conditions
- Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate, Gingival Recession, Generalized, Gingival Recession, Localized
- Trial name
- NCT07158528
- Testing
- coronally advanced flap with connective tissue graft, tunneled coronally advanced flap with a connective tissue graft
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Ghent
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Gingival Recessions, Gingival Recession, Mucogingival Surgery
Optimizing Clinical Outcomes in CAF + SCTG: the Impact of Compressive Sutures
This randomized controlled clinical trial aims to evaluate the additional effect on clinical outcomes of compressive sutures associated with coronally advanced flap (CAF) and subepithelial connective tissue graft (SCTG) for the…
- Conditions
- Gingival Recessions, Gingival Recession, Mucogingival Surgery, Suture
- Trial name
- NCT06701786
- Testing
- Compressive Sutures (CSs) group, Without Compressive Sutures (WCSs) group
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Refractory Granulomatous Lobular Mastitis
Surgical Intervention for Refractory Granulomatous Lobular Mastitis
Granulomatous lobular mastitis (GLM) belongs to a group of benign diseases, which is mainly treated with glucocorticoids and surgical treatment.
- Trial name
- NCT04637711
- Testing
- Focus clearing + whole breast exploration and washing + one-stage micro plastic surgery No Intervention: Extensive lesion excision
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Wuhan University
Flap Ischemia, Hypoxia
Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap Reconstructions
This study is a single-center, observational study designed to collect tissue spectrometric data.
- Trial name
- NCT07786610
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Breast Cancer
Effect of Breast Implants om Mammography Screening
The purpose of the study is to survey how many women have breast implants in the mammography screening population and the effect of implants on the number and type of examinations and on costs.
- Trial name
- NCT05222100
- Testing
- Mammography screening
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Vastra Gotaland Region
Gingival Recession, Localized, Gingival Recession, Plastic Surgery
Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Premandibula.
Multiple techniques can be used for recession coverage. The most common techniques are : tunnel technique (T), coronally advanced flap (CAF) or a combination of both (TCAF).
- Conditions
- Gingival Recession, Localized, Gingival Recession, Plastic Surgery, Gingival Recessions, Gingival Recession, Mucogingival Surgery
- Trial name
- NCT06940050
- Testing
- Coronally advanced flap with a connective tissue graft, Tunneled coronally advanced flap with a connective tissue graft
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Ghent
Pancreatic Cancer, Malignant Biliary Obstruction
Comparison of a Short Modified Metal Stent Versus Plastic Stent as a Bridge to Surgery in Pancreatic Cancer With Malignant Biliary Obstruction
This study is a multicenter, randomized clinical trial designed to compare the effectiveness and safety of a modified 8-mm fully covered self-expandable metal stent (FCSEMS) with a conventional plastic stent for preoperative…
- Trial name
- BRIDGE-8 (NCT07606430)
- Testing
- Modified 8-mm Fully Covered Self-Expandable Metal Stent, Plastic stent
- Volunteers
- 116 people
- Sponsor
- Soonchunhyang University Hospital
Self Esteem
Impact of Plastic and Aesthetic Surgery on Self-esteem
The primary objective of QUALIPLAST is to evaluate the impact of plastic and aesthetic surgery interventions on patients' self-esteem.
- Trial name
- QUALIPLAST (NCT06865794)
- Testing
- Questionnaire and Physical Exam
- Where
- 2 sites in France
- Volunteers
- 1,500 people
- Sponsor
- Hospices Civils de Lyon
Physiologic Venous Dilation, Air Travel
Prospective Repeated-Measures Study of Popliteal Vein Diameter During the First 48 Hours After Commercial Air Travel to Bogota for a Plastic Surgery Intervention
This prospective repeated-measures study will evaluate how long popliteal vein dilation persists after international commercial air travel to Bogota.
- Trial name
- NCT07808411
- Testing
- Commercial Air Travel Exposure, Standardized Bilateral Popliteal Vein Duplex Ultrasound
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Research Inc
Microtia, Congenital, Microtia
Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction
This study aims to improve surgical outcomes for children and young adults with ear differences severe secondary to congenital conditions (like microtia, a condition where the ear is underdeveloped), trauma (such as dog bites)…
- Conditions
- Microtia, Congenital, Microtia, Microtia-Anotia, Ear Deformities, Acquired
- Trial name
- NCT07154667
- Testing
- Use of AuryzoN™ EAR 2.0 device, Hand carving
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nemours Children's Clinic