Clinical trials: Platelet Rich Plasma
Diabetic Neuropathies, Chronic Pain
Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain
Peripheral neuropathy is very common in diabetes mellitus (DM). Till now there is no available effective therapy for this pathology.
- Trial name
- NCT03601494
- Testing
- perineural injection of platelet-rich plasma, medical
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Low Back Pain, Platelet Rich Plasma
Comparison of IntraArticular Platelet-Rich-Plasma to Corticosteroid Injections for Patients With Zygapophyseal Joint (Z-Joint) Low Back Pain Confirmed by Dual Intra-Articular Local Anesthetic Injections
Comparison of IntraArticular Platelet-Rich-Plasma to Corticosteroid Injections for Patients with Zygapophyseal Joint (Z-Joint) Low Back Pain Confirmed by Dual Intra-Articular Local Anesthetic Injections: A Triple Blinded…
- Conditions
- Low Back Pain, Platelet Rich Plasma, Zygapophyseal Joint Arthritis
- Trial name
- NCT05188820
- Testing
- PRP - platelet rich plasma injection, Cortisone injection
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Osteo Arthritis Knee, Pain, Chronic
Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis
Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities.
- Trial name
- NCT03886142
- Testing
- radiofrequency, platelet rich plasma injection
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Ovarian Failure, Perimenopausal Disorder
Ovarian Rejuvenation Using Platelet Rich Plasma (PRP) & Autologous Tissue Stromal Vascular Fraction (tSVF) and Cell Enriched tSVF
Trial of imaging guided intra-ovarian injection to improve ovarian function in clinical settings of Premature Ovarian Failure, Perimenopausal and /or early postmenopausal symptomatology and related hormonal deficiencies.
- Conditions
- Ovarian Failure, Perimenopausal Disorder, Hormone Disturbance
- Trial name
- OVAR-REJUV (NCT04444245)
- Testing
- lipoaspiration harvest tSVF, Platelet Rich Plasma, Endovaginal Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Black Tie Medical, Inc.
Knee Osteoarthritis
Effects of Platelet-Rich Plasma and Ozone Therapy in Knee Osteoarthritis
Knee osteoarthritis can frequently occur with advancing age. In cases of pain that persists despite hot/cold applications, drug therapy and exercise, intra-articular injections are considered.
- Trial name
- NCT06631456
- Testing
- PRP injection, Ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Lumbar Facet Joint Syndrome
The Role of Intra-articular Injection of PRP Versus Corticosteriods in Treatment of Lumbar Facet Disease
Low back pain is an extremely common health problem and recent studies have shown that nearly up to 52% of patients have low back pain caused by lumbar facet joint syndrome.
- Trial name
- PRP (NCT04860531)
- Testing
- Lumbar Facet Joints intra-articular injection with Platelet Rich Plasma, Lumbar Facet Joints intra-articular injection with a mixture of 0.5% lidocaine and 5mg/ml of betamethasone
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Knee Osteoarthritis
High Frequency Intensive Autologous PRP Injection and Genicular Nerve Blocks in Treating Knee Osteoarthritis
Osteoarthritis (OA) of the knees is the most common degenerative disorder seen in a rehabilitation outpatient clinic. It is characterized by structural changes in the articular cartilage and the surrounding tissues.
- Trial name
- NCT04088045
- Testing
- Autologous platelet rich plasma and 5% dextrose solution injections.
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Temporomandibular Joint Disorders, Temporomandibular Joint Pain
PRP vs HA Intra-articular Injections in TMDs
This clinical trial aims to compare the multidirectional mandibular mobility following the treatment of TMJ disorders with same-protocol intra-articular injections of PRP and HA.
- Trial name
- NCT06530745
- Testing
- Hyaluronic acid (HA) injection, Platelet-rich plasma (PRP) injection
- Where
- Poland
- Volunteers
- 81 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Post-acne Atrophic Scars
Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars
This study compares the outcome of two procedures for the treatment of atrophic acne scars.
- Trial name
- NCT06978361
- Testing
- Microneedling with autologous Platelet Rich Plasma, Microneedling with topical insulin
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Khyber Teaching Hospital
Treatments of Striae Gravidarum
The Combination Therapy of Fractional Laser and PRP Compared With Nanofat Grafting and PRP Synergy in Treating Striae Gravidarum.
Nowadays, multiple treatment modalities have been applied clinically to treat striae gravidarum, such as laser therapy, microdermabrasion, platelet-rich plasma injection(PRP), etc.
- Trial name
- NCT03328871
- Testing
- Fractional CO2 Laser, Nanofat grafting, Platelet-rich plasma (PRP) Injection
- Where
- China
- Volunteers
- 10 people
- Sponsor
- First Affiliated Hospital of Jinan University
Rotator Cuff Injuries, Shoulder Joint
Platelet-Rich Plasma Versus Home-Based Exercise for Partial-Thickness Supraspinatus Tears
This study evaluates the clinical effectiveness of platelet-rich plasma (PRP) injections compared with a home-based exercise program in patients with partial-thickness tears of the supraspinatus tendon.
- Conditions
- Rotator Cuff Injuries, Shoulder Joint, Shoulder Pain
- Trial name
- NCT07246434
- Testing
- Platelet-Rich Plasma (PRP), Home Exercise Program
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Extremadura
Leg Ulcer, Diabetic Foot
Autologous Transplantation of BM-ECs With Platelet-Rich Plasma Extract for the Treatment of Critical Limb Ischemia
The intent of this clinical study is to evaluate the safety of the injection composed of autologous bone marrow derived endothelial cells (BM-ECs) and platelet-rich plasma extract (PRPE) for the treatment of critical limb…
- Conditions
- Leg Ulcer, Diabetic Foot, Gangrene, Peripheral Vascular Disease
- Trial name
- NCT02993809
- Testing
- BM-ECs and PRPE, BM-ECs
- Volunteers
- 40 people
- Sponsor
- South China Research Center for Stem Cell and Regenerative Medicine
Osteoarthritis (OA), Knee Injury
Investigating the Safety and Regenerative Potential of MSC-Derived Secretome Combined With PRGF in Knee Osteoarthritis
This Phase I/II randomized clinical trial investigates the safety, feasibility, and early regenerative potential of intra-articular administration of mesenchymal stem cell (MSC)-derived secretome combined with Plasma Rich in…
- Conditions
- Osteoarthritis (OA), Knee Injury, Cartilage Degeneration
- Trial name
- PRGFSECKOA (NCT07157891)
- Testing
- MSC-Derived Secretome, MSC-Derived Secretome + Autologous PRGF
- Volunteers
- 25 people
- Sponsor
- University of the Punjab
Knee Osteoarthritis
Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis
Osteoarthritis (OA) of the knees is the most common degenerative disorder seen in a rehabilitation outpatient clinic. It is characterized by metabolic, biochemical, and structural changes in the articular cartilage and the…
- Trial name
- NCT04006314
- Testing
- Autologous platelet rich plasma and dextrose solution.
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Thumb Carpometacarpal Joint Osteoarthritis
Platelet-rich Plasma for Thumb Carpometacarpal Joint Osteoarthritis
The purpose of this study is to investigate a case series of patients treated with Platelet-rich plasma for thumb carpometacarpal joint osteoarthritis.
- Trial name
- NCT04886349
- Testing
- Platelet-rich plasma
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Mayo Clinic
Ovarian Failure, Infertility, Female
Ovarian Rejuvenation for Premature Ovarian Insufficiency and Poor Ovarian Response
The objective of this study is to perform a prospective randomized controlled trial seeking to characterize the effects of intra-ovarian injection of platelet rich plasma (PRP) on biomarkers of ovarian reserve as well as IVF…
- Trial name
- NCT04163640
- Testing
- intra-ovarian platelet rich plasma injection
- Where
- 2 sites in United States, Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Osteoarthritis, Knee
PRP-HA Versus HA in Knee Osteoarthritis
Osteoarthritis (OA) is a prevalent chronic condition which most commonly affects the knee. The pathogenesis of OA involves initial mechanical stress resulting in cartilage lesions, leading to inflammatory processes causing joint…
- Trial name
- NCT05076526
- Testing
- Hyaluronic acid (Synolis VA), Cellular Matrix platelet-rich-plasma with hyaluronic acid (CM PRP-HA)
- Volunteers
- 132 people
- Sponsor
- Singapore General Hospital
Shoulder Tendinopaty
Comparison Between Platelet Rich Plasma and Corticosteroids for the Treatment of Rotator Cuff Tendinopathy
The goal of this clinical trial is to test if Plateth-rich plasma would provide improved pain relief and function in patients with rotator cuff tendinopathy compared to standard treatment of corticosterone injections.
- Trial name
- NCT06150378
- Testing
- Corticosteroid, Plathet rich plasma
- Where
- Argentina
- Volunteers
- 100 people
- Sponsor
- Hospital Italiano de Buenos Aires
Unilateral Cleft Lip
Effect of Platelet Rich Plasma (PRP) on the Esthetic Outcome and Scar Formation of Unilateral Cleft Lip Repair
The purpose of this study is to evaluate effect of platelet rich plasma on scar formation of unilateral cleft lip repair.
- Trial name
- NCT02958306
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Olfactory Disorder, Olfaction Disorders
Intranasal Injection of PRP Versus Saline for Treatment of Olfactory Dysfunction
This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PrP) in the treatment of olfactory dysfunction.
- Conditions
- Olfactory Disorder, Olfaction Disorders, Olfactory Nerve Injuries, Olfactory Nerve Disorder
- Trial name
- NCT04406584
- Testing
- Injection into olfactory cleft
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University