Clinical trials: Platelets Rich Plasma
Degenerative Lesion of Articular Cartilage of Knee
Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the…
- Trial name
- NCT02090140
- Testing
- ADSC Application, Microfracture
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Surgical Site Infection (SSI), Mediastinitis
Use of Platelet-Rich Plasma to Reduce Sternal Wound Complications After CABG With Median Sternotomy
The goal of this clinical trial is to learn whether applying autologous platelet-rich plasma (PRP) to the sternal wound during heart surgery improves wound healing and reduces complications after surgery.
- Conditions
- Surgical Site Infection (SSI), Mediastinitis, Delayed Wound Healing
- Trial name
- NCT07352020
- Testing
- Autologous Platelet-Rich Plasma (PRP) Application, Standard Sternal Wound Closure
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Genitourinary Syndrome of Menopause (GSM)
Vaginal Platelet-Rich Plasma and Vaginal Histology in Genitourinary Syndrome of Menopause
This study evaluates whether subepithelial injection of autologous platelet-rich plasma (PRP) into the vaginal wall produces histological changes consistent with tissue regeneration in postmenopausal women with genitourinary…
- Trial name
- NCT07905820
- Testing
- Autologous Platelet-Rich Plasma (PRP), 0.9% sodium chloride (normal saline)
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Knee Osteoarthritis
Platelet-rich Plasma and Synovial Cytokines in Knee Osteoarthritis
A prospective study was performed on 90 patients were included and categorized into mild (30 cases, moderate (30 cases) and severe (30 cases) knee OA. Three intra-articular (I.A) injections of PRP, 2 weeks a part, were received.
- Trial name
- NCT04754685
- Testing
- Intra-articular injection of platelet-rich plasma
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Valley University
Plantar Fasciitis, Steroid
Platelet Rich Plasma Injection Compared With Steroid Injection for the Treatment of Plantar Fasciitis
Plantar fasciitis (PF) is the one of the most common orthopaedic problem resulting in heel pain. Previous evidence suggests that Platelet Rich Plasma (PRP) injection has better outcome in the long run as compared to the local…
- Conditions
- Plantar Fasciitis, Steroid, Platelet-rich Plasma (PRP)
- Trial name
- NCT04985396
- Testing
- Platelet Rich Plasma (PRP) group
- Where
- Nepal
- Volunteers
- 78 people
- Sponsor
- Armed Police Force Hospital, Nepal
Lateral Epicondylitis (Tennis Elbow)
Comparison of Platelet Rich Plasma and Alternative Therapies for the Treatment of Tennis Elbow (Lateral Epicondylitis)
"Tennis elbow" is the most common cause of lateral elbow pain, generally caused by either work or sports related repetitive strain.
- Trial name
- IMPROVE (NCT01668953)
- Testing
- Platelet Rich Plasma (PRP) Injection, Whole Blood Injection, Dry Needle Fenestration
- Where
- 2 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse
Efficacy of Platelet Rich Plasma on Pelvic Floor Muscle Strength and Recurrence Rate in Pelvic Organ Prolapse Surgery
Pelvic organ prolapse (POP) is a common pelvic floor disorder associated with impaired quality of life and considerable postoperative recurrence following native tissue repair.
- Conditions
- Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Platelet Rich Plasma Injection
- Trial name
- NCT07746739
- Testing
- POP surgery adjunctive PRP
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Andalas University
Knee Osteoarthritis
Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis
Osteoarthritis (OA) of the knees is the most common degenerative disorder seen in a rehabilitation outpatient clinic. It is characterized by metabolic, biochemical, and structural changes in the articular cartilage and the…
- Trial name
- NCT04006314
- Testing
- Autologous platelet rich plasma and dextrose solution.
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Covid19, Sars-CoV-2 Infection
Management of Cytokine Storms in Severe COVID-19 Patients With Autologous Activated Platelet-rich Plasma Therapy
The positive cases of coronavirus disease-2019 (COVID-19) in Indonesia has been increasing rapidly since the first case found in March 2020 to date.
- Conditions
- Covid19, Sars-CoV-2 Infection, ARDS, Human, Severe covid19
- Trial name
- NCT04715360
- Testing
- autologous activated platelet-rich plasma, Avigan
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Hayandra Peduli Foundation
Lung Cancer
Platelet-Rich and Concentrated Platelet-Poor Plasma to Reduce Air Leak Post-Lobectomy: A Randomized Controlled Trial
The purpose of this study is to determine whether the use of platelet-rich plasma (PRP) and concentrated platelet-poor plasma (PPPc) can reduce the duration of post-operative air leak after lobectomy for lung tumours.
- Trial name
- NCT00665912
- Testing
- Standard post-lobectomy wound care plus use of PRP and PPPc prepared by GPS and Plasmax respectively, Standard post-lobectomy wound care
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Zimmer Biomet
Androgenetic Alopecia
Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia: A Systematic Review and Meta-analysis
assess the literature on PRP outcomes for AGA, with a focus on specific clinical outcomes in a comparative view, in accordance with PRISMA statement for reporting this meta-analysis
- Trial name
- PRP IN AGA (NCT04191005)
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Jasim Mohammed Alshammari
Chronic Patellar Tendinopathy
Chronic Patellar Tendinopathy (PT)is Prevalent in Participants of Several Sports.A Three-arm, Single-blind Randomized Controlled Trial Will be Conducted. We Want to Compare the Clinical Effectiveness of ESWT Alone, ESWT Combined With Hyaluronic Acid, and ESWT Combined With PRP in Athletes With PT
Chronic patellar tendinopathy is highly prevalent among youth, amateur, and elite athletes, with rates reaching 30-40% in high-performance populations.
- Trial name
- NCT07819968
- Testing
- Extracorporeal Shock Wave Therapy, Hyaluronic Acid (HA), Platelet-Rich Plasma
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Chang Gung Memorial Hospital
Platelets Rich Plasma, Saline
Platelets Rich Plasma Injection Versus Physiologic Saline Injection for Treatment of Myofascial Pain
The aim of this is to compare the usage of Platelet-Rich Plasma (PRP) and Physiologic Saline injection in management of myofascial pain dysfunction (MPD).
- Conditions
- Platelets Rich Plasma, Saline, Myofascial Pain
- Trial name
- NCT07901920
- Testing
- Platelet-rich plasma, Physiologic saline
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Pilonidal Disease of Natal Cleft
Effect of Platelet Rich Plasma on Healing of Operated Pilonidal Sinus by Open Method
The aim of the study is to assess the healing promotion effect of platelet rich plasma in patient being operated for sacrococcygeal pilonidal sinus disease by open excision
- Trial name
- NCT04430413
- Testing
- Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Subacromial Impingement Syndrome, Partial Thickness Rotator Cuff Tear
Treatment of the Rotator Cuff Disease With Platelet Rich Plasma Injection
The purpose of this investigator initiated study is to clinically evaluate the efficacy of a new treatment for subacromial impingement syndrome and partial thickness rotator cuff tears.
- Trial name
- NCT01123889
- Testing
- platelet rich plasma injection, corticosteroid injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Loma Linda University
Class II Division 1 Malocclusion
The Effect of Autologous Platelet Concentrations on Orthodontic Treatment Time
60 patients needed therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines were divided to randomly three groups: (1) PRP group: Received PRP injections, (2) I-PRF group…
- Trial name
- NCT05335824
- Testing
- The platelet-rich plasma (PRP), The injectable platelet-rich fibrin (I-PRF) group, The control group
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Thin Endometrium, Endometrial Disorder
Autologous Platelet-Rich Plasma (PRP) and Endometrial Thickness
The goal of this interventional study is to evaluate the increasing in endometrial thickening after the intrauterine infusion of 0,5-1 ml of autologous Platelet-Rich Plasma (PRP) and the implantation rate in women with thin…
- Conditions
- Thin Endometrium, Endometrial Disorder, Endometrial Thickness Not Growing Under Estrogen Stimulation
- Trial name
- NCT03067623
- Testing
- PRP, Tomcat catheter
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University Magna Graecia
Greater Trochanteric Pain Syndrome
Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial)
Greater Trochanteric Pain Syndrome (GTPS), also known as Trochanteric Bursitis, is a painful condition predominantly affecting middle aged women.
- Trial name
- NCT03479190
- Testing
- ultrasound guided injection of Platelet rich plasma, ultrasound guided injection of Normal Saline
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Rotator Cuff Tears
PRP for Rotator Cuff Tears
Regenerative medicine, specifically orthobiologics is a hot topic in the community and in Sports Medicine. Riding the hype curve of a new treatment can be great when offering new procedures to patients.
- Trial name
- NCT06422390
- Testing
- Platelet - Rich Plasma
- Where
- United States
- Sponsor
- Scripps Clinic
Osteoarthritis
PRP vs HA Intra-articular Knee Injections for Cartilage Defects
Study Title: A cohort comparison study Comparing Platelet Rich Plasma vs Hyaluronic Acid Intra-articular Knee Injections for Early Cartilage Defects in the knee.
- Trial name
- NCT02012530
- Testing
- HA, PRP
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Shetty-Kim Research Foundation