Clinical trials: Platelets Rich Plasma
Hip Necrosis, Hip Injuries
The Treatment of Initial Stage of Hip Osteonecrosis: the Core Decompression
This retrospective study evaluates 52 cases of avascular necrosis of femoral head (AVN) treated by core decompression, bone chips allograft, fibrin platelet rich-plasma (PRF) and concentrated autologous mesenchymal stromal cells…
- Trial name
- NEC15 (NCT04210440)
- Testing
- Core decompression procedure
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Dante Dallari, MD
Knee Osteoarthritis, Hyaluronic Acid
Efficacy at One Year of Combined Injections of Plasma Rich in Platelets and Hyaluronic Acid in Knee Osteoarthritis
The French Society of Rheumatology cannot rule on the value of intra-articular injections of PRP due to the lack of hindsight and insufficient data.
- Conditions
- Knee Osteoarthritis, Hyaluronic Acid, Platelet Rich Plasma
- Trial name
- ISPAG (NCT05039463)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Androgenetic Alopecia (AGA)
PRP Combined With Botulinum Toxin Type A Injection for the Treatment of Androgenetic Alopecia: A Study
Research Purpose The objective of this study is to determine the safety and efficacy of combined PRP and BTX-A injection therapy for Androgenetic Alopecia (AGA).
- Trial name
- AGA (NCT07335367)
- Testing
- Injection of PRP combined with Botulinum Toxin Type A into the alopecic area(s), PRP-only injection into the alopecic area
- Where
- China
- Volunteers
- 83 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Melasma (Facial Melasma)
Efficacy and Safety of Triple-Combination Cream Plus Microneedling Along With Tranexamic Acid Versus Platelet-Rich Plasma in the Treatment of Moderate-to-Severe Melasma: A Randomized Comparative Study
Background Melasma is a chronic acquired pigmentary disorder characterized by symmetrical hyperpigmented macules and patches, predominantly affecting the face.
- Trial name
- NCT07893067
- Testing
- Group B (Triple Combination Cream + Microneedling + Platelet-Rich Plasma)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Treatments of Striae Gravidarum
The Combination Therapy of Fractional Laser and PRP Compared With Nanofat Grafting and PRP Synergy in Treating Striae Gravidarum.
Nowadays, multiple treatment modalities have been applied clinically to treat striae gravidarum, such as laser therapy, microdermabrasion, platelet-rich plasma injection(PRP), etc.
- Trial name
- NCT03328871
- Testing
- Fractional CO2 Laser, Nanofat grafting, Platelet-rich plasma (PRP) Injection
- Where
- China
- Volunteers
- 10 people
- Sponsor
- First Affiliated Hospital of Jinan University
Dry Eye Syndromes
Study of Platelet Rich Plasma Drops to Moderate Clinically Significant Dry Eye
This is a single center double-masked study with up to four visits. Subjects who have been diagnosed with dry-eye syndrome at Flaum Eye Institute will be enrolled.
- Trial name
- NCT05121493
- Testing
- Platelet Poor Plasma Tear Drops, Platelet Rich Plasma Tear Drops
- Where
- United States
- Sponsor
- University of Rochester
PCOS (Polycystic Ovary Syndrome)
Optimal Allogeneic PRP Concentration for Oocyte In Vitro Maturation in Women With PCOS
In vitro maturation is a long-studied technique used to obtain mature oocytes outside the human body. However, this method can increase the risk of ovarian hyperstimulation syndrome (OHSS), particularly in patients with…
- Trial name
- NCT07514234
- Testing
- PRP plasma rich platelets
- Where
- Indonesia
- Volunteers
- 15 people
- Sponsor
- Gadjah Mada University
Shoulder Osteoarthritis
Effect of PRP as Therapy for Shoulder Osteoarthritis
Patients with shoulder osteoarthritis are suffering from pain and disabilities which lead to difficulties in life. The presence of platelet-rich plasma as regenerative therapy which helps in healing of damaged tissues like…
- Trial name
- NCT05043493
- Testing
- Injection in the intraarticular space of glenohumeral joint
- Where
- Egypt
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Knee Osteoarthritis
To Evaluate the Optimum Dose of Platelet Rich Plasma in Knee Osteoarthritis and Compare Efficacy With Hyaluronic Acid
Randomized, Double-blind, 12-month, placebo-controlled study was conducted on 100 outpatients . Intervention platelet rich plasma( PRP) prepared from 60 ml of blood by adding novel step of filtration to manual centrifuge step to…
- Trial name
- NCT04198467
- Testing
- Platelet rich plasma, Hyaluronic Acid
- Volunteers
- 100 people
- Sponsor
- Dr. Himanshu Bansal Foundation
Diabetic Foot Ulcers, Diabetic Wound
The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
The aim of this study is to evaluate the chance of non-healing diabetic foot ulcers repair by improving the condition of lack of oxygen or hypoxia in the wound area caused by diabetes using methylene blue along with the use of…
- Trial name
- NCT05850611
- Testing
- Methylene Blue, Milk (control), Methylene Blue and Platelet-Rich Plasma-Fibrin Glue
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Musculoskeletal Pain, Low Back Pain
Biotensegrity: Thoracolumbar Fascial Integrity in Chronic Low Back Pain
This is a prospective study on chronic low back pain patients aimed at investigating how findings on a physical examination and musculoskeletal ultrasound may correlate with myofascial damage in the lower back.
- Conditions
- Musculoskeletal Pain, Low Back Pain, Myofascial Pain
- Trial name
- NCT03940313
- Testing
- Prolotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ProloAustin
Knee Arthritis, Osteoarthritis
Platelet-Rich Plasma Composition and Clinical Effects in Knee Osteoarthritis
This is a prospective, observational cohort study involving 40 patients with primary knee osteoarthritis hospitalized in a rehabilitation hospital in Cluj-Napoca.
- Trial name
- NCT07558980
- Testing
- intra-articular administration of plasma rich in platelets (PRP)
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Menopause, Menopause Ovarian Failure
Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation
SEGOVA procedure includes - Stem cell therapy, G - Growth factor Platelet Plasma Rich therapy and in Vitro Activation of the ovaries.
- Conditions
- Menopause, Menopause Ovarian Failure, Ovarian Failure, Premature Ovarian Failure
- Trial name
- SEGOVA (NCT04009473)
- Testing
- SEGOVA procedure
- Where
- 3 sites in Malta, North Macedonia and 1 more
- Volunteers
- 100 people
- Sponsor
- Forever Young d.o.o.
Anosmia
Value of Platelet-Rich Plasma in Post Severe Acute Respiratory Syndrome Coronavirus 2
The study will be conducted to evaluate : The efficacy of Platelet Rich plasma in treatment of smell disorders post severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via the growth factors involved in accelerating and…
- Trial name
- NCT05395845
- Testing
- platelets rich plasma
- Volunteers
- 88 people
- Sponsor
- Aya abdelnasser hassani
Tendinopathy, Enthesopathy
Hyaluronic Acid Versus Platelet-Rich Plasma for Chronic Tendinopathy and Enthesopathy
Chronic tendinopathies and enthesopathies are common musculoskeletal conditions in orthopedics and sports medicine, frequently leading to pain, impaired function, and significantly reduced quality of life.
- Conditions
- Tendinopathy, Enthesopathy, Achilles Tendinopathy, Golfer's Elbow
- Trial name
- NCT07714811
- Testing
- Hyaluronic acid injection, Autologous Platelet-Rich Plasma Injection
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Ortonika Orthopedic Medical Clinic in Lublin
Carpal Tunnel Syndrome
Platelet Rich Plasma in Carpal Tunnel Syndrome
The aim of this study is to evaluate the effect of local platelet rich plasma injection therapy in patients with mild to moderate idiopathic carpal tunnel syndrome (CTS) with clinical and electrophysiological parameters.
- Trial name
- NCT04000932
- Testing
- Local platelet rich plasma (PRP) injection-T-Lab PRP kit, Local steroid injection-Diprospan ®, Schering Plough
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Baskent University
Androgenic Alopecia
Autologous Stromal Vascular Fraction in Treatment of Male Androgenic Alopecia
Evaluation of Safety and efficacy of autologous stromal vascular fraction derived from denovo versus platelet rich plasma enhanced donner site in treatment of male androgenic alopecia
- Trial name
- NCT06326359
- Testing
- autologous stromal vascular fraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Aortic Dissection Type A, Transfusions
Use of PRP in Open Surgery for Type A Aortic Dissection
The goal of this clinical trial is to determine if autologous platelet rich plasma (PRP) can reduce the need for blood transfusions in patients undergoing open surgery for Type A aortic dissection.
- Conditions
- Aortic Dissection Type A, Transfusions, Platelet Rich Plasma (PRP), Organ Protection
- Trial name
- NCT07005661
- Testing
- Autologous Platelet Rich Plasma, Standard Blood Management
- Volunteers
- 250 people
- Sponsor
- Beijing Anzhen Hospital
Platelet-Rich Plasma, Meniscus Lesion
Platelet-rich Plasma for Menical Tear
Meniscal injuries are a common pathology among athletes, and have an impact on the daily or sporting practice of patients. Surgical approach implies sometimes heavy consequences.
- Trial name
- NCT04040283
- Testing
- Platelet-rich plasma (PRP) therapy
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- University of Malaga
Spontaneous Intracranial Hypotension
Autologous Platelet-rich Plasma Versus Whole Blood for Epidural Patch in Spontaneous Intracranial Hypotension
Spontaneous intracranial hypotension (SIH) is a condition characterized by refractory orthostatic headache, mostly due to leaks of cerebrospinal fluid (CSF).
- Trial name
- NCT07602556
- Testing
- PRP Patch group, Whole Blood Patch Group
- Volunteers
- 218 people
- Sponsor
- Beijing Tiantan Hospital