Clinical trials: Platelets Rich Plasma
Cesarean Section Wound, Platelet-rich Plasma (PRP)
Efficacy of Platelet-rich Plasma in Improving Postoperative Scarring After Cesarean Delivery
Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regenerative medicine to promote healing and…
- Conditions
- Cesarean Section Wound, Platelet-rich Plasma (PRP), Regenerative Medicine
- Trial name
- PRP06081992 (NCT06978010)
- Testing
- Platelet-Rich Plasma (PRP) intraoperatively
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Erectile Dysfunction
Evaluating the Efficacy of Platelet-Rich-Plasma (PRP) for Erectile Dysfunction
There is great interest in restorative therapies (platelet-rich plasma (PRP) injections, shockwave therapy and stem cell therapy) for ED given their non-invasive nature.
- Trial name
- NCT06264635
- Testing
- Platelet-Rich-Plasma, Saline
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sprain of Ankle
Use of Platelet Rich Plasma Therapy for Acute Ankle Sprains in the Emergency Department
This research study hopes to determine whether or not platelet rich plasma therapy improves healing time of moderate to severe ankle sprain in comparison to standard of care therapy.
- Trial name
- PRP (NCT01518335)
- Testing
- Platelet rich plasma injection
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Albert Einstein Healthcare Network
Pelvic Organ Prolapse
Platelet Rich Plasma as an Adjunct Therapy at the Time of Transvaginal Native Tissue Prolapse Surgery
The purpose of the study is to evaluate the surgical outcomes of injecting platelet-rich plasma (PRP) into the vaginal tissue as an adjunct therapy at the time of prolapse surgery
- Trial name
- PRP (NCT05731284)
- Testing
- Platelet rich plasma (PRP) Injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Lumbar Herniated Disc
Assesment of Epidural Platelet-Rich Plasma (PRP) Injection During Uniportal Endoscopic Lumbar Disc Herniation Excision on Residual Neuropathies
The aim of this study is to assess neuropathic pain in the lower limb at 6 months post-operation in patients who have undergone surgery for a lumbar disc herniation using single-port endoscopic discectomy combined with an…
- Trial name
- HERDISPLA (NCT07770750)
- Testing
- Uniportal endoscopic lumbar disc herniation removal
- Where
- France
- Volunteers
- 50 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Poor Ovarian Response, Ovarian Reactivation
Proteomic and Biological Characterisation of Plasma for the Study of Changes Following Ovarian Reactivation Treatment
The samples used in PRGF treatments owe their effectiveness to the handling, concentration, and preservation of their components, which explains why samples obtained with different platelet-rich plasma preparation systems may…
- Trial name
- NCT07376460
- Testing
- Platelet Rich Plasma + BMDSCs mobilization
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Oral Ulcer Due to Pemphius Vularis, Oral Ulcer Due to Benign Mucous Membrane Pemphioid
PRF in Management of Chronic Multiple Oral Ulcers
PRF in orabase will be applied as a pack material on chronic oral ulcers of chronic multiple oral lesions compared to conventional topical steroid therapy with clobetasol propionate 0.05% in orabase.
- Conditions
- Oral Ulcer Due to Pemphius Vularis, Oral Ulcer Due to Benign Mucous Membrane Pemphioid, Oral Ulcer Due to Steven Johnson's Syndrome
- Trial name
- NCT03878771
- Testing
- Platelet rich fibrin gel in Orabase, Dermovate cream in Orabase
- Where
- Egypt
- Volunteers
- 804 people
- Sponsor
- Beni-Suef University
Acne Vulgaris
Platelet-rich Plasma With Topical Retinoids Versus Topical Retinoids Alone in Acne Vulgaris
Acne vulgaris is the most common skin disease in adolescents and young adults. Adult or post-adolescent acne occurs in 12-14% of this population.It is a chronic, inflammatory disease of the pilosebaceous unit .The clinical…
- Trial name
- NCT06281782
- Testing
- topical retinoids and platalet rich plasma
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Linear Atrophic Scars
Comparative Analysis of Intralesional Platelet-Rich Plasma, NPH Insulin, and Vitamin C- A New Horizon and Future Hope for Linear Atrophic Scar Management
The aim of this clinical trial is to evaluate the efficacy and safety of platelet-rich plasma, insulin and vitamin C in the management of linear atrophic scars.
- Trial name
- NCT07901283
- Testing
- Intradermal injection of autologous platelet rich plasma, Intradermal injection of NPH insulin, Intradermal injection of Vitamin C
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Aya Ashraf Fouda
Post-Traumatic Osteoarthritis of Knee
Early Regenerative Intervention for Post-Traumatic Osteoarthritis
The goal of the proposed research is to compare the ERIPTO protocol for post-traumatic osteoarthritis of the knee with that of bone marrow aspirate concentrate (BMAC) only.
- Trial name
- ERIPTO (NCT04222140)
- Testing
- ERIPTO Protocol, BMAC Only
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Affinity Health Research Institute
Trochanteric Syndrome
Comparison Between Transarterial Musculoskeletal Embolization and Platelet-Rich Plasma Injection for the Treatment of Greater Trochanteric Pain Syndrome
Greater Trochanteric Pain Syndrome (GTPS) is a common cause of lateral hip pain that can significantly affect daily activities and quality of life.
- Trial name
- HIPE (NCT07396246)
- Testing
- Transarterial Musculoskeletal Embolization, Platelet-Rich Plasma Injection
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Temporomandibular Joint Disc Displacement
Comparative Efficacy of Platelet Rich Plasma and Dry Needling in Management of Anterior Disc Displacement of Temporomandibular Joint
Pain and trismus are of the prime concerns for the patients in case of Anterior disc displacement ADD of temporomandibular joint (TMJ). In the recent times, PRP has has produced promising results in management of TMDs.
- Trial name
- NCT05532098
- Testing
- Dry Needling, PRP
- Where
- India
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Autologous Platelet-rich Plasma Supplement, Sperm Cryopreservation
The Effects of Autologous Platelet-rich Plasma Supplement During Sperm Cryopreservation on Post-cryopreserved Sperm Quality
Sperm cryopreservation is an essential procedure for male fertility in certain situations, like cancer, vasectomy or other obstructive surgeries, autoimmunity diseases, immunosuppressive therapeutic strategies, or when the male…
- Conditions
- Autologous Platelet-rich Plasma Supplement, Sperm Cryopreservation, Post-cryopreserved Sperm Quality, Semen Analysis
- Trial name
- NCT06258759
- Testing
- autologous platelet-rich plasma supplement, no autologous platelet-rich plasma supplement
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Thumb Osteoarthritis
A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base
Randomized comparison between Platelet Rich Plasma (PRP) and placebo (Saline) for thumb base.osteoarthritis.
- Trial name
- NCT04218591
- Testing
- PRP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Trigeminal Neuralgia, Idiopathic, PRP
The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for the Trigeminal Neuralgia
Trigeminal neuralgia (TN), characterized by brief, recurrent paroxysms of lancinating pain in the distribution of 1 or more branches of the trigeminal nerve (fifth cranial nerve [CNV]), is one of the most common, severe forms of…
- Trial name
- NCT06472323
- Testing
- PRF+PRP, PRF
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Beijing Tiantan Hospital
Stress Urinary Incontinence (SUI)
The Effect of Periurethral Injection of Platelet Rich Plasma Versus Mid-urethral Sling in Treatment of Stress Urinary Incontinence
this study used to compare efficacy between platelet rich plasma periurethral injection versus mid urethral sling ( trans obturator tape ) in treatment of stress urinary incontinence
- Trial name
- NCT07550426
- Testing
- Platelet Rich Plasma, Mid urethral sling ( trans obturator tape)
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Poor Ovarian Response
A RCT Study on Autologous Cell Injection Into the Ovaries of Patients With POR
Poor ovarian response (POR) is a pathological state where the ovaries do not respond well to the stimulation of gonadotropins. It is mainly characterized by a small number of developing follicles, a high cancellation rate of the…
- Trial name
- NCT07282288
- Testing
- PRP injection, SVF injection
- Volunteers
- 198 people
- Sponsor
- Peking University Third Hospital
Pressure Injuries - Stage 3, Pressure Injuries - Stage 4
Platelet Rich Plasma Combined With Human Umbilical Cord Mesenchymal Stem Cells for Stage 3 and 4 Stress Injury
This study is an open-label, single-center trial which aim to evaluate of efficacy and safety of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) combined with platelet-rich plasma (PRP) in stage 3 and 4 stress…
- Trial name
- NCT06302582
- Testing
- Platelet-rich plasma (PRP) combined with human umbilical cord mesenchymal stem cells (huMSCs), Control group
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Liaocheng People's Hospital
Osteoarthritis Knee, Corticosteroid
Intra-articular Platelet Rich Plasma vs Corticosteroid in Treatment of Knee Osteoarthritis Patients
Knee osteoarthritis is the most common type of osteoarthritis in the lower extremity and constitutes 23% of all arthritis cases, about 13% of females and 10% of males aged above 60 years have symptomatic knee OA.
- Conditions
- Osteoarthritis Knee, Corticosteroid, Platelet Rich Plasma
- Trial name
- NCT05742061
- Testing
- Corticosteroid, Platelet Rich Plasma
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University