Clinical trials: Platelets Rich Plasma
Anosmia, COVID-19
Effectiveness and Safety of Platelet Rich Plasma (PRP) on Persistent Olfactory Dysfunction Related to COVID-19
Olfactory dysfunction (OD) is a well know symptom of coronavirus disease 2019 (COVID-19), accounting for 48 to 85% of patients. In 1 to 10% of cases, patients develop a chronic olfactory dysfunction (COD,) lasting more than 6…
- Trial name
- NCT05226546
- Testing
- Platelet rich plasma (PRP), olfactory training
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Asherman Syndrome
Effects of Platelet Rich Plasma on Endometrium
Intrauterine platelet rich plasma will be injected in the endometrial region via the vaginal route after the cessation of menstrual period.
- Trial name
- NCT04424160
- Testing
- PRP injection in the endometrium
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Acibadem University
Knee Osteoarthritis
Intra-Articular Platelet Rich Plasm Use in Osteoarthritis of Knee.
Osteoarthritis of the knee is a very prevalent disease. However, there are few therapeutic options for its patients. Platelet-rich plasma is a treatment option for chronic pain.
- Trial name
- NCT03086759
- Testing
- platelet rich plasm, Triamcinolone Hexacetonide, Isotonic Saline Solution
- Where
- Brazil
- Volunteers
- 99 people
- Sponsor
- Federal University of São Paulo
Chronic Low Back Pain
Intra-discal Injection of PRP for Low Back Pain
Low back pain (LBP) is the second cause of medical visits in France. Indeed, its incidence can vary between 60 and 90%. LBP is also the leading cause of disability in the adult population in France and in the rest of the world.
- Trial name
- MODI-PRP (NCT03712527)
- Testing
- Injection of Platelet rich plasma, Injection of NaCl
- Where
- 6 sites in France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Montpellier
Retinitis Pigmentosa
Management of Retinitis Pigmentosa Via Electromagnetic Stimulation and Platelet Rich Plasma
The aim of this study is to investigate whether natural progression rate can be slowed down with subtenon PRP or PRP application combined with rEMS in retinitis pigmentosa cases.
- Trial name
- rEMS (NCT04252534)
- Testing
- PRP combined Magnovision, PRP
- Volunteers
- 60 people
- Sponsor
- Ankara Universitesi Teknokent
Unrestorable Dentition, Post-Extraction Sockets
An Assessment of Bone Augmentation in Post-Extraction Sockets
When a tooth is extracted the ridge of bone that held the tooth in place begins to heal and over time new bone grows to fill the empty space left by the missing tooth.
- Trial name
- FMD-007 (NCT00641316)
- Testing
- AtraumaticTeeth Extraction, Atraumatic Teeth Extraction/Grafted Extraction Sockets
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Premature Ovarian Insufficiency, Intrauterine Adhesion
Application of Platelet-rich Plasma (PRP) in Reproductive Medicine
Female fertility is affected by many factors, such as ovarian function, fallopian tube patency, uterine environment, and mental state, among which the ovaries and endometrium are more important.
- Conditions
- Premature Ovarian Insufficiency, Intrauterine Adhesion, Poor Ovarian Response, Repeated Implantation Failure
- Trial name
- NCT06645379
- Testing
- Platelet-Rich Plasma (PRP) Injections
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Anterior Cruciate Ligament Tear
Tunnel Widening in Augmented ACL Integration Via PrP Enriched Collected Autologous Bone vs Standard ACL Technique
The purpose of this clinical study is to compare the outcomes of two surgical techniques for reconstruction of the anterior cruciate ligament (ACL) after a single, primary ACL rupture.
- Trial name
- NCT05953051
- Testing
- ACL reconstruction with bone/PrP-composite, ACL reconstruction (Standard)
- Where
- Switzerland
- Volunteers
- 107 people
- Sponsor
- Schulthess Klinik
Rotator Cuff Tears, Rotator Cuff Tendinitis
Treatment of Rotator Cuff Tears With Platelet Rich Plasma
The purpose of this study is to evaluate the safety and effectiveness of dual platelet rich plasma (PRP) injections into the rotator cuff insertion and the area of the tendon proximal to the insertion.
- Trial name
- NCT06481046
- Testing
- Platelet Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Skin Wrinkling
Autologous Platelet Rich Plasma Combined to Hyaluronic Acid Obtained With Regen-Kit BCT-HA in Aesthetic Medicine
The aim of this prospective study is to assess the efficacy of autologous Platelet Rich Plasma combined with Hyaluronic Acid prepared with RegenKit-BCT HA Cellular Matrix on skin rejuvenation.
- Trial name
- NCT02832583
- Testing
- Regenkit BCT-HA Cellular Matrix
- Volunteers
- 31 people
- Sponsor
- Regen Lab SA
Tennis Elbow
Efficacy of Injection Therapy for Lateral Epicondylosis
While evidence does not identify any conventional therapy as definitive for chronic lateral epicondylosis (CLE, tennis elbow), basic science and limited pilot level trials support rigorous assessment of prolotherapy (PrT) and…
- Trial name
- NCT01476605
- Testing
- Dextrose prolotherapy, PrT-DMS, Platelet Rich Plasma injection
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Alopecia Areata
Comparative Study Efficacy and Safety of of Activated Versus Non-Activated PRP
This was comparative prospective study conducted on 40 subjects, diagnosed with alopecia areata of 40 the scalp, carried in a period from February 2020 and March 2021
- Trial name
- NCT05251831
- Testing
- Intradermal injection
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Knee Osteoarthritis
Effects of Steroid, Dextrose Prolotherapy, and Platelet-Rich Plasma Injections in Knee Joint OA Patients
The novelty of thisstudy lies in its comparative assessment of three latest intra-articular injection therapies including steroid injections, dextrose prolotherapy, and PRP, for knee OA associated impairments, with a focus on…
- Trial name
- NCT07243392
- Testing
- Intra articular steroid injection, Intra articular PRP, Intra articular dextrose prolotherapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Lincoln University College
Post Operative Pain
The Effect of Platelet Rich Plasma (PRP) on Post Operative Pain in Anterior Cruciate Ligament Reconstruction
The purpose of this research study is to investigate whether or not platelet rich plasma (PRP) may help to improve tendon healing and decrease post operative pain in patients undergoing anterior cruciate ligament (ACL)…
- Trial name
- NCT01765712
- Testing
- Anterior Cruciate ligament reconstruction bone patellar tendon bone autograft, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brian Walters
Degenerative Chondropathy, Early Osteoarthritis
Platelet Rich Plasma Injection for Knee Pain
Platelet-rich plasma (PRP) has been used as an alternative to non-operative treatments for increasing the rate of cure in bone and soft-tissue regeneration, although there are very few clinical studies regarding the treatment of…
- Trial name
- NCT01747018
- Testing
- Platelet-rich Plasma
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- The Catholic University of Korea
Chronic Venous Hypertension With Ulcer and Inflammation, Chronic Ulcer of Leg or Foot
Role of Platelet Rich Plasma in Enhancing Graft Take in Chronic Venous Ulcers
Chronic venous ulcers are considered a problem with a big morbidity impact on both the health facilities and patients, skin-grafting have shown not so perfect outcomes with such ulcers.
- Trial name
- NCT03526913
- Testing
- PRP, STSG
- Volunteers
- 20 people
- Sponsor
- Noha Mohsen Omar
Alveolar Bone Loss
Effect of Buccal Fat Pad Derived Stem Cells in Maxillary Sinus Augmentation
In this study the buccal fat pad derived stem cells (BFPSCs) will be harvested from buccal fat pad tissue of patients receiving maxillary sinus augmentation.
- Trial name
- NCT02745379
- Testing
- BFPSCs+ DFDBA+ PRF, DFDBA + PRF
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Erectile Dysfunction
Clinical Trial to Evaluate the Efficacy of Intracavernosal Infusion of PRP vs PPP for the Erectile Dysfunction.
Randomized, double-blind clinical trial to evaluate efficacy, feasibility and safety with two groups in a 1:1 ratio; where the control group corresponds to patients who will receive Platelet Poor plasma and an experimental group…
- Trial name
- PRePED (NCT04502875)
- Testing
- PRP, PPP
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Puerta de Hierro University Hospital
Paraosmia
Randomized Clinical Trial of Intranasal Injection of Platelet-Rich Plasma for Treatment of Parosmia
This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PRP) in the treatment of qualitative olfactory dysfunction (parosmia).
- Trial name
- NCT06283745
- Testing
- Platelet-rich Plasma (PRP), Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Sciatica
Pain Relief by Platelet-rich Plasma (PRP) Treatment
Past PRP therapy is not sufficient for some part of patients.In this clinical research, The integrated application of PRP with extracellurar matrix and some type of stem cell technique.
- Trial name
- NCT01749839
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saint Bernard Mission University