Clinical trials: Platelets Rich Plasma
Penile Hypospadias
Pearls and Pitfalls in Usage of Plasma-Rich Platelet Graft Versus Dartos Flap in Distal Penile Hypospadias Repair
Hypospadias is the most common congenital anomaly of penis. It is the second most common genital birth defect in boys after cryptorchidism The reinforcement of hypospadias repair with an intermediate layer is believed to reduce…
- Trial name
- NCT06808139
- Testing
- Plasma-Rich Platelet Graft, Dartos Flap
- Volunteers
- 70 people
- Sponsor
- Assiut University
Nonunion of Fracture
Platelet-rich Plasma Combined With Conventional Surgery in the Treatment of Atrophic Nonunion of Femoral Shaft Fractures
To objectively analyze the effectiveness of platelet-rich plasma (PRP) combined with conventional surgery in the treatment of atrophic nonunion of femoral shaft fractures.
- Trial name
- NCT03129971
- Testing
- conventional surgery, autologous platelet-rich plasma
- Volunteers
- 92 people
- Sponsor
- Qinghai University
Knee Osteoarthritis
Optimal Articular Solutions With Intraosseous and Synovial Platelet-Rich Plasma
This is a prospective cohort clinical study. Due to logistic constraints at the sites of implementation, a randomized allocation will not be feasible (private clinic).
- Trial name
- OASIS-PRP (NCT06520059)
- Testing
- Platelet rich-plasma - PRP - intraosseous and intra-articular admnistration
- Where
- 2 sites in Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Osteoarthritis of the Shoulder, Corticosteroid
Comparing Platelet Rich Plasma and Corticosteroid for Military & Civilian Patients With Glenohumeral Osteoarthritis
Shoulder arthroplasty provides successful improvement in pain and function for the treatment of end stage osteoarthritis (OA) of the shoulder in the older patient population (Sanchez 2008, Sampson 2010, Kon 2012, Fitzpatrick…
- Conditions
- Osteoarthritis of the Shoulder, Corticosteroid, PRP, Pain
- Trial name
- PRP (NCT05160441)
- Testing
- Platelet Rich Plasma Injection, Corticosteroid Injection, Delayed Platelet Rich Plasma Injection After Corticosteroid Injection Failure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Walter Reed National Military Medical Center
Wrinkle
Association of Photobiomodulation With Platelet Rich Plasma Intradermal Injection for Facial Rejuvenation
Skin aging is an irreversible, slow and progressive process. It is influenced mainly by age, but also by external factors such as ultraviolet radiation, smoking, alcohol, among others.
- Trial name
- NCT04145999
- Testing
- PRP application, Photobiomodulation
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Knee Osteoarthritis, Cartilage Degeneration
Platelet Rich Plasma Injection for Knee Osteoarthritis
The research questions of this study are; 1. Is platelet rich plasma (PRP) treatment effective in knee osteoarthritis (OA)? 2. What are the indications for PRP treatment? 3.
- Trial name
- NCT04454164
- Testing
- PRP, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ferhat Say
Injectable Plasma-rich Fibrin Versus Low-Level Laser Therapy on Othodontic Movement
Assessment of Different Orthodontic Tooth Movements Assisted With Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
The present prospective clinical study will be undertaken for assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy onthe rate of different orthodontic tooth movements,
- Trial name
- NCT05966987
- Testing
- Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Autologous Blood Transfusion
Autologous Platelet-rich Plasma (aPRP) for Complex Aortic Arch Surgerymacrovascular Operation
Perioperative blood loss continues to be a serious problem in complex aortic arch surgery using deep hypothermic circulatory arrest (DHCA). Major blood loss causes increased morbidity and mortality [1].
- Trial name
- NCT02572440
- Testing
- Sorin XTRA/Sorin Group,
- Where
- China
- Sponsor
- Beijing Anzhen Hospital
Knee Osteoarthritis
Platelet-rich Plasma in Symptomatic Knee Osteoarthritis
Intro: Platelet rich plasma (PRP) is largely used in various musculoskeletal disorders such as chronic tendinopathies but also osteoarthritis (OA).
- Trial name
- PIKOA (NCT05378815)
- Testing
- PRP injection
- Where
- 2 sites in France
- Volunteers
- 210 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus Foot Ulcer
Platelet Rich Plasma and Autologous Fat Graft for Diabetic Ulcer
Conventional management of diabetic ulcers is associated with slow healing, high costs and repeated trips to clinic. Stem cells contained in fat grafts can differentiate into pro-healing cells and release growth factors with…
- Trial name
- NCT03085550
- Testing
- Fat grafting, Fat grafting + platelet rich plasma
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University College, London
Arthroplasty, Replacement
Wound Additives in Primary Total Joint Athroplasty
3 cohorts of total joint patient of 30 members each were randomized to receive PRP or Activated Collegen or no additive were studied for status of the wound at 6 weeks and recorded all complications, infections and reoperations.
- Trial name
- NCT03158623
- Testing
- Platelet Rich Plasma, Cellerate
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salt Lake Orthopedic Clinic
Pilonidal Sinus, Pilonidal Disease
Application of Platelet-rich Plasma in Pilonidal Sinus Disease
Pilonidal sinus disease is a common health-care problem, and surgical excision is the standard treatment modality. Controversy still exists regarding the best surgical technique for treating pilonidal disease in terms of…
- Conditions
- Pilonidal Sinus, Pilonidal Disease, Wound Heal, Quality of Life
- Trial name
- NCT04697082
- Testing
- Open surgery, Minimal invasive surgery, Platelet rich plasma administration
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Cihangir Akyol
Impacted Third Molar Tooth
Effectiveness of Platelet Rich Plasma in Wound Healing
Purpose: This prospective randomized comparative clinical study was conducted to assess the effect of platelet-rich plasma (PRP) gel on soft tissue healing and bone regeneration potential on lower third molar extraction sockets.
- Trial name
- NCT02831374
- Testing
- Local anesthesia, surgical extraction of impacted third molar, Preparation of PRP gel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Linyi People's Hospital
Bronchopleural Fistula
PRP Efficacy and Safety in BPF
Platelet-rich plasma(PRP), is a concentrate of platelet-rich plasma protein derived from whole blood. The main components of it are platelets, leukocytes and fibrin.
- Trial name
- NCT05304897
- Testing
- PRP treatment
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Genitourinary Syndrome of Menopause
Comparison of Vaginal Hyaluronic Acid Treatment Over Autologous Platelet Rich Plasma Treatment for Genitourinary Syndrome of Menopause
Genitourinary syndrome of menopause (GSM) is a collection of symptoms and signs caused by hypoestrogenic changes to the labia majora/minora, clitoris, vestibule/introitus, vagina, urethra, and bladder that occur in menopausal…
- Trial name
- NCT05571527
- Testing
- Platelet Rich Plasma treatment, Vaginal Hyaluronic Acid supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Atrophic Rhinitis
Evaluation of Efficacy of Platelet Rich Plasma as Anew Modality for Treatment of Atrophic Rhinitis
An interventional hospital based study will be undertaken from February 2021 to February 2023 in order to determine the efficacy of platelet rich plasma as a new modality for treatment of patients suffering from atrophic rhinitis…
- Trial name
- NCT04717960
- Testing
- nasal submucosal injection of platelet rich plasma
- Volunteers
- 40 people
- Sponsor
- Sohag University
Anal Fistula
BIOlogic Augmented Repair of Complex Anal Fistula Using Acellular Matrix and/or Autologous Platelet-rich Plasma
The purpose of this study is to compare the clinical effectiveness of augmenting surgical repair of complex anal fistula using autologous PRP and/or micronized acellular porcine urinary bladder matrix (UBM) to usual surgical care…
- Trial name
- BIO RAMP (NCT05805449)
- Testing
- Surgery, Platelet-rich plasma (PRP), Matrix
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetic Foot Ulcer (DFU), Ulcer
Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Diabetic Foot Ulcers
To prospectively evaluate the safety and efficacy of an Autologous Platelet-Rich Fibrin Plasma system when applied in conjunction with Standard of Care for management of chronic Diabetic Foot Ulcers.
- Conditions
- Diabetic Foot Ulcer (DFU), Ulcer, Wound Closure, Wound Management
- Trial name
- NCT07840378
- Testing
- PRFM, Standard of Care (SoC)
- Volunteers
- 55 people
- Sponsor
- Tiger Biosciences, LLC.
PRP, Knee Osteoarthritis
IA Injection of Rejoint Gel and PRP in Patients With Unilateral Knee OA
To assess the safety and tolerability of intra-articular Injection doses of Rejoint Gel after platelet-rich plasma administration in unilateral knee OA subjects.
- Trial name
- NCT04519047
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Lipofilling, Human Autologous Fat Transfer
The Use of Activated Platelet Rich Plasma (PRP) in Human Autologous Fat Transfer
In this prospective, randomized clinical trial, lipofilling of the midface with Platelet Rich Plasma (PRP) is compared with lipofilling of the midface without PRP.
- Trial name
- NCT01461785
- Testing
- Addition of PRP ( platelet rich plasma) to the lipograft, Lipofilling of the midface
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bergman Clinics