Clinical trials: Platelets Rich Plasma
Epicondylitis, Lateral Humeral, Tennis Elbow
Evaluation of Three Types of Injection for the Treatment of Lateral Epicondylalgia
The primary objective of this study is to compare the evolution of pain profiles among patients suffering from lateral epicondyalgia (tennis elbow) following three types of treatment: PRP-L injection versus type A botulinum toxin…
- Trial name
- LET (NCT02325063)
- Testing
- PRP-L Injection, Botox injection, Corticoid injection
- Where
- 2 sites in France
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Knee Instability
Patellar Tendon Regeneration With Platelet-rich Plasma
The central third of the patellar tendon is used as a donor site for anterior cruciate ligament (ACL) reconstruction. After months or years the harvest site partially regenerates.
- Trial name
- NCT01111747
- Testing
- Platelet-rich plasma, Control group
- Volunteers
- 27 people
- Sponsor
- University of Sao Paulo General Hospital
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Lateral Epicondylitis of the Elbow
Identification of Responders to Platelet-Rich Plasma (PRP) Injections in Lateral Elbow Epicondylalgia
The goal of this non-interventional study is to identify patients who respond to platelet-rich plasma (PRP) injections for chronic lateral epicondylalgia (tennis elbow) and to investigate factors associated with treatment…
- Trial name
- EPIC-PRP (NCT07496983)
- Where
- France
- Volunteers
- 139 people
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Deep Retinal Capillary Ischemia, Paracentral Acute Middle Maculopathy
Management of Deep Retinal Capillary Ischemia by Electromagnetic Stimulation and Platelet- Rich Plasma
To investigate the efficacy of retinal electromagnetic stimulation and sub-tenon autologous platelet rich plasma in the treatment of deep retinal capillary ischemia.
- Conditions
- Deep Retinal Capillary Ischemia, Paracentral Acute Middle Maculopathy, Acute Macular Neuroretinopathy
- Trial name
- rEMS (NCT04242719)
- Testing
- Electromagnetic stimulation, Platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara Universitesi Teknokent
Osteoarthritis
Leukocyte-rich PRP vs Leukocyte-poor PRP for the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial
Platelet-rich Plasma (PRP) is the most exploited biologic agents currently used for the treatment of osteoarthritis (OA) of different joints, in particular knee OA.
- Trial name
- PRP014 (NCT02923700)
- Testing
- Leukocyte-rich PRP intra-articular injections, Leukocyte-poor PRP intra-articular injections
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Istituto Ortopedico Rizzoli
PRP Injection Only, Physiotherapy Only
Platelet-rich Plasma Injections and Physiotherapy in the Treatment of Chronic Rotator Cuff Tendinopathy
The investigators aim to investigate whether combination of PRP injection with physiotherapy program could produce superior effect than either treatment alone.
- Conditions
- PRP Injection Only, Physiotherapy Only, PRP and Physiotherapy
- Trial name
- NCT03133416
- Testing
- PRP preparation, Physiotherapy, PRP and physiotherapy
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Knee Osteoarthritis
Bone Marrow Aspirate Compared to Platelet Rich Plasma for Treating Knee Osteoarthritis
This study is intended to compare whether bone marrow aspirate concentrate or platelet rich plasma injections is more effective in treating knee osteoarthritis.
- Trial name
- EmCyte (NCT03289416)
- Testing
- Pure PRP II, PureBMC
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Andrews Research & Education Foundation
Knee Osteoarthristis, Cartilage Damage
Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems
The investigators would like to study the differences in the quality of Platelet Rich Plasma (PRP) between two different machines in those with knee osteoarthritis.
- Conditions
- Knee Osteoarthristis, Cartilage Damage, Platelet Rich Plasma, Platelet Rich Plasma Injection
- Trial name
- PRP-PEPC (NCT07491367)
- Testing
- Platelet Rich Plasma, Emcyte PurePRP Supraphysiologic Concentrating System, APEX Biologix XCELL PRP System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Patellar Tendinopathy, Achilles Tendinopathy (AT)
Evaluation of Platelet-Rich Plasma (PRP) Treatment in Tendinopathies
This multicenter, prospective, observational study, based on real-world evidence (RWE), aims to evaluate the efficacy and safety of Platelet-Rich Plasma (PRP) treatment across four types of tendinopathies: patellar, Achilles…
- Conditions
- Patellar Tendinopathy, Achilles Tendinopathy (AT), Epicondylitis, Lateral, Plantar Fasciitis, Chronic
- Trial name
- RWE-TDP-PRP (NCT07558564)
- Testing
- Platelet rich plasma (PRP)
- Where
- 5 sites in Spain
- Volunteers
- 2,000 people
- Sponsor
- ReSport Clinic
Geographic Atrophy, Dry Age Related Macular Degeneration
Subtenon PRP Injection for Geographic Atrophy in Dry Age-Related Macular Degeneration
This study investigates the effects of subtenon autologous platelet-rich plasma (PRP) injections on retinal structure and visual function in patients with advanced dry age-related macular degeneration (AMD).
- Trial name
- GA-PRP (NCT07428798)
- Testing
- Subtenon Autologous Platelet-Rich Plasma Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Glossopharyngeal Neuralgia, Pulsed Radiofrequency
Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet Rich Plasma to Treat Idiopathic Glossopharyngeal Neuralgia (GPN)
To investigate the efficacy and safety of the application of PRF combined PRP to the for the treatment of GPN.
- Conditions
- Glossopharyngeal Neuralgia, Pulsed Radiofrequency, Platelet Rich Plasma
- Trial name
- NCT06931457
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Beijing Tiantan Hospital
Tendon Entrapment
Effectiveness of Platelet-rich Plasma for Treatment of Trigger Finger
Study purpose is to evaluate the effectiveness of Platelet-rich Plasma (PRP) injection in the treatment of trigger finger. We compare PRP to a corticosteroid (methylprednisolone) injection in a prospective randomized triple-blind…
- Trial name
- NCT04167098
- Testing
- PRP injection, Corticosteroid injection
- Where
- Finland
- Volunteers
- 117 people
- Sponsor
- Töölö Hospital
Osteoarthritis, Knee
Intraosseous With Intra-articular Injection of Platelet Rich Plasma in Treatment of Knee Osteoarthritis
The aim of this study was to compare the efficacy of treatment in three groups of patients with knee osteoarthritis (OA) given a combination of intraosseous with intra-articular injection of platelet rich plasma (PRP)…
- Trial name
- NCT03329235
- Testing
- PRP, HA
- Volunteers
- 86 people
- Sponsor
- Cangzhou Central Hospital
Knee Chondropathy, Osteoarthritis, Knee
Platelet-rich Plasma vs Viscosupplementation in the Treatment of Knee Articular Degenerative Pathology
The investigators hypothesized that intra-articular injections of Platelet-rich Plasma (PRP) to treat knee degenerative articular cartilage pathology could determine pain relief and recovery of knee function with overall clinical…
- Trial name
- PRP2009 (NCT01670578)
- Testing
- PRP, Hyaluronic acid
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Istituto Ortopedico Rizzoli
Severe Oligoasthenoteratozoospermia, Sperm Quality
PRP Improves Blastocyst Formation in ICSI Cycles
The goal of this clinical trial is to learn if platelet rich plasma (PRP) works to improve embryo development rates and embryo quality in IVF cycles, involving male adult patients with severe sperm disorders.
- Conditions
- Severe Oligoasthenoteratozoospermia, Sperm Quality, Spermatazoa Disorders, Sperm Parameters in Fertile and Infertile Men
- Trial name
- PRP ICSI SOAT (NCT07579858)
- Testing
- Platelet Rich Plasma
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stella Maris Women and Children Hospital
Management of Stable Vitiligo
Effect of Platelet Rich Plasma on Outcome of Narrow Band UVB in Treatment of Vitiligo; Clinical and Histopathological Study
For each patient, one side of body will be treated with NB-UVB alone while the other side will be treated with NB-UVB therapy in addition to intradermal injection of PRP every 2 weeks.
- Trial name
- NCT06370650
- Testing
- platelet rich plasma, narrow band UVB
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Osteoarthritis, Knee
How Does Platelet Dose Impact Clinical Outcomes After PRP Treatment?
The purpose of this study is to determine which platelet rich plasma (PRP) injection dosage provides the most improvement in a patient's knee pain level at 26 weeks post-injection.
- Trial name
- NCT05330689
- Testing
- PRP injection dose (<5 billion platelets), PRP injection dose (between 5 and <10 billion platelets), PRP injection dose (between 10 and <20 billion platelets)
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Pseudoarthrosis
Humeral Shaft Pseudoarthrosis Treated With Bone Autograft Versus Platelet Rich Plasma
Patients with humeral shaft pseudoarthrosis is going to be treated with a standard protocol with a locking compression plate and bone autograft, and other group of patients treated with platelet rich plasma.
- Trial name
- NCT02520089
- Testing
- bone autograft of iliac crest, Platelet Rich Plasma plus bone autograft
- Where
- Mexico
- Volunteers
- 23 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Cuff Injury, Rotator, Arthroscopic Surgical Procedures
Augmentation of Arthroscopic Rotator Cuff Repair With Reimplantation of Subacromial Bursa Tissue and Platelet-Rich Plasma
The goal of this observational study is to evaluate the clinical and radiographic outcomes of the biological enhancement of the arthroscopic rotator cuff repair with stem cells from the acromial bursa and PRP in individuals who…
- Conditions
- Cuff Injury, Rotator, Arthroscopic Surgical Procedures, Stem Cell, PRP
- Trial name
- NCT07589478
- Testing
- Subacromial Bursa Tissue Reimplantation, Arthroscopic Rotator Cuff Repair, Platelet-Rich Plasma (PRP) Injections
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens