Clinical trials: Platelets Rich Plasma
Vulvar Atrophy
Autologous Platelet Concentrate Combined to Hyaluronic Acid Obtained With Cellular Matrix® BCT-HA Kit and Vulvovaginal Dryness
Vulvovaginal irritation is a frequent complaint among postmenopausal women. Common symptoms of vaginal atrophy include dryness, itching, burning and dyspareunia.
- Trial name
- NCT02966925
- Testing
- Cellular Matrix BCT-HA Kit
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Regen Lab SA
Knee Osteoarthritis
Efficacy of Hyaluronic Acid and Platelet-rich Plasma Combination in Knee Osteoarthritis
The purpose of this study is to evaluate the efficacy of intra-articular injections of combined hyaluronic acid and platelet-rich plasma in knee degenerative joint disease in improving joint function and reducing pain.
- Trial name
- NCT03211650
- Testing
- hyaluronic Acid + platelet-rich plasma, hyaluronic acid, platelet-rich plasma
- Where
- 2 sites in Italy
- Volunteers
- 174 people
- Sponsor
- University of Milan
Peripheral Nerve Injury Upper Limb
Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study
The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults.
- Trial name
- NCT06638008
- Testing
- perineural injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
COPD, Interstitial Lung Disease
An Observational Outcomes Study for Autologous Cell Therapy Among Patients With COPD and Interstitial Lung Disease
The purpose of the Lung Institute is to collect and isolate a patient's own cells and platelet rich plasma (PRP) and deliver the product back to the patient same-day.
- Trial name
- NCT03040674
- Testing
- Cell therapy
- Where
- United States
- Volunteers
- 489 people
- Sponsor
- Lung Institute
Diabetic Foot Ulcers
Evaluate the Safety and Efficacy of RegenKit Autologous PRP Gel for the Treatment of Diabetic Foot Ulcer
Autologous platelet-rich plasma (PRP) gel was reported to have very good outcomes in the treatment of foot ulcers in pilot studies and retrospective uncontrolled trials.
- Trial name
- NCT02402374
- Testing
- Autologous platelet rich plasma gel
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Regen Lab SA
Knee Chondropathy, Knee Early Osteoarthritis
Platelet-rich Plasma (PRP) vs Viscosupplementation for the Treatment of Early Knee Articular Degenerative Pathology
The investigators hypothesized that intra-articular injections of Platelet-rich Plasma (PRP) to treat knee degenerative articular cartilage pathology could determine pain relief and recovery of knee function with overall clinical…
- Trial name
- PRP-012 (NCT02135367)
- Testing
- PRP
- Where
- Italy
- Volunteers
- 185 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anal Fissure Chronic, PRP
Short Term Results of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure
Autologous PRP currently has many uses in surgical and medical therapy. Compared with other regenerative therapies, PRP is easy-to-prepare, low-cost, and does not require complex equipment.
- Trial name
- NCT04320498
- Testing
- prp injection, Anrecta, sitz bath
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- KTO Karatay University
Temporomandibular Joint Disc Displacement
Comparative Efficacy of Platelet Rich Plasma and Dry Needling in Management of Anterior Disc Displacement of Temporomandibular Joint
Pain and trismus are of the prime concerns for the patients in case of Anterior disc displacement ADD of temporomandibular joint (TMJ). In the recent times, PRP has has produced promising results in management of TMDs.
- Trial name
- NCT05532098
- Testing
- Dry Needling, PRP
- Where
- India
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Tendinopathy
Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic Tendinosis
Tendinopathy is a clinical syndrome of chronic pain and tendon degeneration that impairs a person's ability to perform daily activities and recreation.
- Trial name
- NCT01833598
- Testing
- PNT + PRP, PNT alone
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Pilonidal Sinus Disease, Platelet-rich Plasma
The Role of Platelet-rich Plasma Local Injection as Treatment in Improvement of Pilonidal Sinus Surgery Outcomes
The aim of the present study is to find How Platelet-rich plasma treatment improves postoperative recovery in patients with pilonidal sinus disease.
- Conditions
- Pilonidal Sinus Disease, Platelet-rich Plasma, Treatment
- Trial name
- NCT07567586
- Testing
- Group A :Platelet-rich plasma treatment, Group B: Control group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
TMJ Disc Disorder
Therapeutic Effect of Microfragmented Adipose Tissue (Lipogems) Injection on Maximum Interincisal Opening Versus Injectable Platelet-rich Plasma (PRP) for the Treatment of Anterior Disc Displacement With Reduction : A Randomized Clinical Trial
this procedure is to remove inflammatory mediators, reduce friction, stimulate the production of new synovial fluid, eliminate suction-cup effect.
- Trial name
- NCT07107399
- Testing
- microfragmented adipose tissue, platelet-rich plasma
- Volunteers
- 16 people
- Sponsor
- Cairo University
Diabetic Foot Ulcers, Diabetic Wound
The Effect of Platelet-Rich Plasma-Fibrin Glue in Combination With Vitamin E and C for Treatment of Non-healing Diabetic Foot Ulcers
The aim of this study is to evaluates the chance of non-healing Diabetic Foot Ulcers repair by reducing oxidative stress caused by diabetes by taking vitamin E and C supplements along with the use of Platelet-Rich Plasma-Fibrin…
- Trial name
- NCT04315909
- Testing
- PRP-Fibrin Glue, Vitamin E and C
- Where
- Iran
- Volunteers
- 24 people
- Sponsor
- Mashhad University of Medical Sciences
Lung Cancer
Platelet-Rich and Concentrated Platelet-Poor Plasma to Reduce Air Leak Post-Lobectomy: A Randomized Controlled Trial
The purpose of this study is to determine whether the use of platelet-rich plasma (PRP) and concentrated platelet-poor plasma (PPPc) can reduce the duration of post-operative air leak after lobectomy for lung tumours.
- Trial name
- NCT00665912
- Testing
- Standard post-lobectomy wound care plus use of PRP and PPPc prepared by GPS and Plasmax respectively, Standard post-lobectomy wound care
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Zimmer Biomet
Musculoskeletal Pain, Osteoarthritis
Testing the Characteristics of Platelet Rich Plasma in Sports Medicine
This is an observational study that evaluates the characteristics of Platelet Rich Plasma used in the therapy and treatment of musculoskeletal injuries and degenerative joint diseases.
- Trial name
- PRiSM (NCT02726464)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Frozen Shoulder, Adhesive Capsulitis
Comparison of the Effect of Combined Glenohumeral Joint and Subdeltoid Bursa Injection With Platelet-rich Plasma (PRP), Corticosteroid, and Normal Saline in Addition to Physical Therapy for Treatment of Frozen Shoulder
Frozen shoulder, adhesive capsulitis, shoulder, platelet-rich plasma, corticosteroid, injection.
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Shoulder, Platelet-rich Plasma
- Trial name
- NCT05230667
- Testing
- PRP injection (PRP group), Corticosteroid injection (CS group), Normal saline injection (NS group)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Leg Ulcer, Diabetic Foot
Autologous Transplantation of BM-ECs With Platelet-Rich Plasma Extract for the Treatment of Critical Limb Ischemia
The intent of this clinical study is to evaluate the safety of the injection composed of autologous bone marrow derived endothelial cells (BM-ECs) and platelet-rich plasma extract (PRPE) for the treatment of critical limb…
- Conditions
- Leg Ulcer, Diabetic Foot, Gangrene, Peripheral Vascular Disease
- Trial name
- NCT02993809
- Testing
- BM-ECs and PRPE, BM-ECs
- Volunteers
- 40 people
- Sponsor
- South China Research Center for Stem Cell and Regenerative Medicine
Temporomandibular Joint Internal Derangement
Effect of Intraarticular Injection of Tenoxicam and Hyaluronic Acid Versus Platelet-Rich Plasma and Hyaluronic Acid in Temporomandibular Joint Internal Derangement
To compare the effect of intraarticular injection of Tenoxicam and Hyaluronic acid Versus Platelet-rich plasma and Hyaluronic acid in the management of patients with TMJ internal derangement with reduction.
- Trial name
- NCT06572904
- Testing
- Tenoxicam Injectable Product, Hyaluronic Acid 20 MG/1 ML Injection Gel/Jelly
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Poor Ovarian Response, PRP Injection
A RCT Study on Autologous PRP Injection in Patients With POR
Poor ovarian response (POR) is a pathological condition where the ovaries do not respond well to the stimulation of gonadotropins.
- Trial name
- NCT07282314
- Testing
- PRP injection
- Volunteers
- 142 people
- Sponsor
- Peking University Third Hospital
Gingival Diseases, Traumatic Injury
Injectable Platelet Rich Fibrin With Collagen Matrix in Treatment of Multiple Gingival Recession.
This study is proposing the use of i-PRF clot as a scaffold for the XCM in order to obtain a novel biomaterial, incorporating active growth factors and collagen matrix in a single framework, based on the potential effect of i-PRF…
- Trial name
- NCT05389059
- Testing
- CAF+CM, I-PRF
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Osteoarthritis
Intra-articular Injection in the Knee of Adipose Derived Stromal Cells and Platelet Rich Plasma for Osteoarthritis
Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue and platelet rich plasma (PRP) can be obtained from peripheral blood.
- Trial name
- NCT03089762
- Testing
- Intra-articular injection of SVF plus PRP
- Volunteers
- 10 people
- Sponsor
- Bioheart, Inc.