Clinical trials: Platelets Rich Plasma
Osteoarthritis
Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
Clinical study to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma.
- Trial name
- NCT01075230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Exactech
Temporomandibular Disorder
Platelet-rich Plasma Injection for Temporomandibular Disorders
Temporomandibular disorder (TMD) involves the temporomandibular joint (TMJ) and surrounding structure, causing problems including myofascial pain and joint degeneration. TMD is mostly seen in the age group of 18 to 44.
- Trial name
- NCT04127942
- Testing
- platelet-rich plasma injection therapy of TMD
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Impacted Third Molar
Comparative Effects of CGF and PRP in Impacted Third Molar Surgery
This study evaluates the effects of two different blood products obtained from the patient's own blood (Concentrated Growth Factor [CGF] and Platelet-Rich Plasma [PRP]) on healing after wisdom tooth extraction.
- Trial name
- NCT07320170
- Testing
- Concentrated Growth Factor (CGF), Platelet-Rich Plasma (PRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Recep Tayyip Erdogan University
Knee Osteoarthritis
Knee Osteoarthritis and Rehabilitation
Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that causes hypertrophic changes in bone. OA is a non-inflammatory progressive musculoskeletal disease and is one of the most common degenerative…
- Trial name
- NCT06432842
- Testing
- Laser Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Muscle Injury
Platelet-Rich Plasma in Acute Muscle Injuries
OBJECTIVE: To evaluate the effect of Platelet Rich Plasma (PRP) injection in muscle injuries. The investigators check football players in the acute phase of hamstrings or quadriceps injuries. Efficacy and safety are evaluated.
- Trial name
- NCT03676205
- Testing
- PRP, Traumeel
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Thin Endometrium, Endometrial Disorder
Autologous Platelet-Rich Plasma (PRP) and Endometrial Thickness
The goal of this interventional study is to evaluate the increasing in endometrial thickening after the intrauterine infusion of 0,5-1 ml of autologous Platelet-Rich Plasma (PRP) and the implantation rate in women with thin…
- Conditions
- Thin Endometrium, Endometrial Disorder, Endometrial Thickness Not Growing Under Estrogen Stimulation
- Trial name
- NCT03067623
- Testing
- PRP, Tomcat catheter
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University Magna Graecia
Occipital Neuralgia, Headache
Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia
This study is a randomized controlled trial, assessing the effect of a single platelet rich plasma (PRP) injection in post traumatic (concussive) greater occipital neuralgia.
- Trial name
- NCT04051203
- Testing
- Autologous Platelet Rich Plasma Injection, Depo-Medrol and lidocaine, Normal Saline
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Graft-versus-host Disease
Safety and Efficacy of Autologous PRP and PPP Eye Drops in the Treatment of Ocular GVHD
The purpose of this study is to evaluate the safety and efficacy of autologous Platelet Rich Plasma (PRP) and Platelet Poor Plasma (PPP) eye drops four times a day in the treatment of ocular graft versus host disease (O-GVHD).
- Trial name
- NCT02561520
- Testing
- PRP eye drops, PPP eye drops
- Where
- United States
- Sponsor
- Ladan Espandar
Dry Eye Syndromes
Study of Platelet Rich Plasma Drops to Moderate Clinically Significant Dry Eye
This is a single center double-masked study with up to four visits. Subjects who have been diagnosed with dry-eye syndrome at Flaum Eye Institute will be enrolled.
- Trial name
- NCT05121493
- Testing
- Platelet Poor Plasma Tear Drops, Platelet Rich Plasma Tear Drops
- Where
- United States
- Sponsor
- University of Rochester
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Rectal Fistula
Is the Use of Blood Platelets Effective in the Treatment of Difficult Fistulas Related to the Anal Sphincter?
Rationale: Closure of the internal opening is the most accepted standard procedure in the treatment of peri-anal fistulas. The mucosal advancement flap is considered as golden standard.
- Trial name
- NCT01615302
- Testing
- Mucosa advancement flap, Platelet rich plasma (PRP)
- Where
- 6 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Maastricht University Medical Center
Periodontal Regeneration, Wound Healing
Effects of Standard PRP and Extracellular Vesicle-Enriched PRP on Human Gingival Fibroblasts
The goal of this study is to compare the biological effects of two blood-derived products, standard platelet-rich plasma (PRP) and extracellular vesicle-enriched PRP (EV-enriched PRP), on human gingival (gum) fibroblasts, the…
- Conditions
- Periodontal Regeneration, Wound Healing, Fibroblast
- Trial name
- NCT07855822
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Inonu University
Rotator Cuff Tears of the Shoulder
Effect of Platelet-rich Fibrin on Rotator Cuff Repair
The objective of this study was to prospectively evaluate the influence of local application of Platelet Rich Fibrin (PRF) on the functional outcome and integrity of the arthroscopically repaired tendons in patients with massive…
- Trial name
- PRP-Fibrin (NCT01612845)
- Testing
- Arthroscopic repair without platelet rich fibrin, PRF (vivostat ®) administration after rotator cuff repair
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Hospital Universitario La Paz
Osteoarthritis, Knee
Knee Osteoarthritis Treatment With Platelet-rich Plasma
Knee osteoarthritis (KOA) is a disease characterized by cartilage degeneration, synovium inflammation, bone remodeling, osteophyte formation, inflammations and loss of articular function.
- Trial name
- NCT05824806
- Testing
- PRP Protocol A, PRP Protocol B, Hyaluronic acid
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Unilateral Cleft Lip
Effect of Platelet Rich Plasma (PRP) on the Esthetic Outcome and Scar Formation of Unilateral Cleft Lip Repair
The purpose of this study is to evaluate effect of platelet rich plasma on scar formation of unilateral cleft lip repair.
- Trial name
- NCT02958306
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Platelet-Rich Plasma
Effect of Platelet-Rich-Plasma in Spine Fusion
The objective of this study is to evaluate the fusion rate after the use of platelet rich plasma with autolgus bone graft and comparing it with bone graft alone
- Trial name
- NCT03779945
- Testing
- autologous platelet rich plasma, posteriolateral lumbar fusion only
- Volunteers
- 60 people
- Sponsor
- Assiut University
Degenerative Lesion of Articular Cartilage of Knee
Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the…
- Trial name
- NCT02090140
- Testing
- ADSC Application, Microfracture
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Lateral Epicondylitis (Tennis Elbow)
Platelet Rich Plasma Injection vs Percutaneous Tenotomy for Common Extensor Tendinopathy
This is a randomized control trial comparing the use of leukocyte rich platelet rich plasma injections to percutaneous tenotomy for the treatment of chronic common extensor tendinopathy.
- Trial name
- NCT04384809
- Testing
- Leukocyte rich platelet rich plasma, Percutaneous Tenotomy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Osteo Arthritis Knee
Efficacy of Mesotherapy Added to Intra-articular Platelet-rich Plasma (PRP) in Patients With Knee Osteoarthritis
In this study, the investigators aimed to determine whether platelet rich plasma (PRP) and mesotherapy combined treatment is effective on pain and function compared to PRP alone in patients with knee osteoarthritis (OA).
- Trial name
- NCT05329116
- Testing
- Lidocaine 2% Injectable Solution, Platelet-rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Necmettin Yildiz
Pilonidal Disease of Natal Cleft
Effect of Platelet Rich Plasma on Healing of Operated Pilonidal Sinus by Open Method
The aim of the study is to assess the healing promotion effect of platelet rich plasma in patient being operated for sacrococcygeal pilonidal sinus disease by open excision
- Trial name
- NCT04430413
- Testing
- Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University