Clinical trials: Pleura; Effusion
Pleural Effusion Due to Another Disorder (Disorder)
Natural History of Nonspecific Pleuritis Diagnosed After Video-assisted-thoracoscopic-surgery
The investigators want to determine the incidence of malignant disease, type of malignant disease and overall survival in patients diagnosed with NSP after VATS.
- Trial name
- NCT03270228
- Testing
- Nonspecific pleuritis after VATS thoracoscopy
- Where
- Denmark
- Volunteers
- 10,000 people
- Sponsor
- Naestved Hospital
Malignant Pleural Effusion
Interventions for Malignant Pleural Effusions Impact on Fatigue
Malignant Pleural Effusions (MPE) are a common problem with around 40,000 new cases in the UK each year. The presence of an MPE suggests a poor prognosis of on average of 3-12 months.
- Trial name
- IMPE-F (NCT04793607)
- Testing
- Pleural procedures
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Lung Cancer
Sonography After Thoracic Surgery (SATS)
Lung cancer remains the leading cause of mortality from malignant diseases in both men and women worldwide. Following thoracic surgery and pulmonary resection, patients have a surgically induced pneumothorax / hydro-hemothorax…
- Trial name
- NCT01152463
- Testing
- thoracic ultrasound
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Malignant Pleural Effusions (Mpe), Medical Thoracoscopy
Safety and Feasibility of Medical Thoracoscopy Using Single-use Flexible Bronchoscope Versus SemiRigid Pleuroscope in Pleural Effusion
Pleural effusion is a common problem in hospital patients. It may arise from a wide range of diseases. There is a multitude of recognised causes of pleural effusion, and in addition, other pleural conditions such as pleural…
- Conditions
- Malignant Pleural Effusions (Mpe), Medical Thoracoscopy, Pleural Effusion
- Trial name
- FLEXPLEUR2 (NCT07726784)
- Testing
- Single-Use Flexible Bronchoscope, Semi-Rigid Pleuroscope
- Where
- 2 sites in Malaysia
- Volunteers
- 36 people
- Sponsor
- National University of Malaysia
Pleural Effusion
Validity of Pleural Effusion Detection Software
The Chang Gung Pleural Effusion Detection Software is a medical software that can automatically detect whether there is a pleural effusion in Chest X-Ray.
- Trial name
- NCT05903287
- Testing
- Chang Gung Pleural Effusion Detection Software
- Where
- Taiwan
- Volunteers
- 282 people
- Sponsor
- Chang Gung Memorial Hospital
Pleural Effusion
Evaluating Different Modalities for Pleural Adhesiolysis at Assuit University Hospital
interventional randomized clinical trial will be done at Assuit University Hospital ( Chest Department and Caridothoracic surgery department ),and all patients presented with complex septate pleural effusion in whom the symptoms…
- Trial name
- NCT03172052
- Testing
- streptokinase, MESNA (2-mercaptoethane sulfonate Na), Medical thoracoscopy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Artificial Intelligence, Lung Diseases
Retrospective Study of Carebot AI CXR Performance in Preclinical Practice
The purpose of this study is to describe the design, methodology and evaluation of the preclinical test of Carebot AI CXR software, and to provide evidence that the investigated medical device meets user requirements in…
- Conditions
- Artificial Intelligence, Lung Diseases, Pneumothorax, Pleural Effusion
- Trial name
- NCT05594485
- Testing
- Carebot AI CXR
- Where
- Czechia
- Volunteers
- 127 people
- Sponsor
- Carebot s.r.o.
NSCLC
Detection of EGFR Mutation in Malignant Pleural Effusion of Lung Cancer Patients and Cancer Cell Lines Establishment
1. Detection EGFR mutation of cancer cells from malignant pleural effusion. 2. Established the cancer cell lines with without EGFR mutation from malignant pleural effusion.
- Trial name
- EGFR (NCT00752076)
- Testing
- cancer cell lines establishment
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Pleural Diseases
Ultrasonography Guided Pleural Biopsy Versus Computed Tomography Guided Pleural Biopsy
This study aims to compare the diagnostic efficiency and reliability of Abrams' needle pleural biopsy under computerized tomography guidance with that of cutting-needle pleural biopsy under ultrasonography guidance in patients…
- Trial name
- NCT01196585
- Testing
- CT-Guided pleural needle biopsy with Abrams' needle, Ultrasonography guided cutting pleural needle biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Eskisehir Osmangazi University
Pulmonary Tuberculosis, Genetic Variants of Host
Toll-like Receptor 2 Gene Polymorphism, Serum Cytokines and Susceptibility to Disease Severity or Treatment Response of Pulmonary Tuberculosis
Infection with Mycobacterium tuberculosis remains at epidemic levels globally. Innate and adaptive immune responses evolve as protective mechanisms against mycobacterial infection in humans.
- Conditions
- Pulmonary Tuberculosis, Genetic Variants of Host, Immune Response of Host
- Trial name
- NCT00772408
- Where
- 2 sites in Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pleural Effusion, Chronic Kidney Disease
Pleural Effusion Types in Chronic Kidney Disease
The purpose of this observational study is to understand the causes of pleural effusion (a buildup of fluid around the lungs) in patients with advanced Chronic Kidney Disease (CKD Stages 3 to 5).
- Trial name
- NCT07547852
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pleural Effusion, Cancer
Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions
This is a randomized control trial of patients with suspected malignant pleural effusions to compare whether patients who have a thoracentesis or pleuroscopy (pleural biopsy) obtain an adequate biopsy, achieve a diagnosis, and…
- Trial name
- PERFECT-MPE (NCT06892691)
- Testing
- Pleuroscopy first, Thoracentesis first
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Thoracentesis, Pleural Effusions, Chronic
GRAvity- Versus Wall Suction-drIven Large Volume Thoracentesis: a RAndomized Controlled Study (GRAWITAS Study)
The primary objective of this study is to compare gravity-driven versus wall suction-driven large volume therapeutic thoracentesis on the development of chest discomfort during the procedure.
- Conditions
- Thoracentesis, Pleural Effusions, Chronic, Pulmonary Edema
- Trial name
- NCT05131945
- Testing
- Standard Suction Thoracentesis, Gravity Thoracentesis
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- M.D. Anderson Cancer Center
Fallopian Tube Cancer, Metastatic Cancer
ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of ILX-295501 in treating patients who have stage III or…
- Conditions
- Fallopian Tube Cancer, Metastatic Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00005645
- Testing
- ILX-295501
- Where
- 8 sites in United States
- Sponsor
- Genzyme, a Sanofi Company
Non-Small Cell Lung Cancer
Multicenter Observational Study of Advanced Non-small Cell Lung Cancer With Malignant Pleural Effusion
Multicenter observational study for correlation between tumor mutation burden and immunotherapy efficacy of advanced non-small cell lung cancer with malignant pleural effusion
- Trial name
- NCT04263688
- Testing
- Non-Intervention
- Volunteers
- 300 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Pleural Effusion
Role of Cryobiopsy in Diagnosis of Pleural Effusion
The purpose of this study is to evaluate the feasibility, size and quality of the specimens obtained by cryoprobe in comparison to those specimens obtained by flexible forceps during medical thoracoscopy in diagnosis of pleural…
- Trial name
- NCT03828903
- Testing
- Cryoprobe
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University