Clinical trials: Pleural Effusion Disorder
Lung Neoplasms
Sensitivity of PDL-1-analysis From Pleural Effusion in Non-small Cell Lung Cancer
This is a prospective diagnostic pilot study to create hypotheses regarding immunocytochemistry (ICC) PD-L1 analysis of pleural effusions in NSCLC patients as compared to the reference standard of PD-L1 immunohistochemistry…
- Trial name
- NCT02855281
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Malignant Pleural Effusion, Stage IV Metastatic Cancer
A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion
This is a Phase Ib/II clinical trial to evaluate the feasibility of administering talimogene laherparepvec into the intrapleural space of subjects with malignant pleural effusion through a pleurX catheter.
- Conditions
- Malignant Pleural Effusion, Stage IV Metastatic Cancer, Lung Cancer
- Trial name
- NCT03597009
- Testing
- Talimogene laherparepvec (TVEC), Nivolumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Brenner Tumor, Malignant Ascites
Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
This randomized phase II trial studies how well metformin hydrochloride and combination chemotherapy works in treating patients with stage III-IV ovarian, fallopian tube, or primary peritoneal cancer.
- Conditions
- Brenner Tumor, Malignant Ascites, Malignant Pleural Effusion, Ovarian Clear Cell Cystadenocarcinoma
- Trial name
- NCT02122185
- Testing
- metformin hydrochloride, Chemotherapy
- Where
- 10 sites in United States
- Volunteers
- 111 people
- Sponsor
- University of Chicago