Clinical trials: Pneumonia in Children
COVID-19, SARS-CoV-2
Clinical and Immunological Characterisation of COVID-19 in Children, Adolescents and Adults
The investigators aim to characterise Coronavirus Disease 2019 (COVID-19) in every age group. On the one hand, emphasis is put on the initial presentation, clinical course, outcome and the therapy used.
- Trial name
- NCT04341168
- Testing
- this study is non- interventional
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- University Hospital of Cologne
Pneumonia
Accuracy of Clinical and Diagnostic Studies for Pneumonia in Children
Pneumonia continues to be a leading cause of death in children under five years of age worldwide. Many studies have evaluated clinical signs and symptoms that may predict pneumonia.
- Trial name
- NCT03630380
- Testing
- Clinical History, Physical Exam Findings, Laboratory Findings
- Where
- Nepal
- Volunteers
- 1,000 people
- Sponsor
- Patan Academy of Health Sciences
COVID-19, COVID-19 Pandemic
COVID-19, Obesity and Lifestyle in Children - Role of Professionals
In this study it is researched how preventive and curative healthcare for children with overweight and obesity was conducted during the Covid-19 pandemic, which barriers were noticed by professionals, and how new methods (such as…
- Conditions
- COVID-19, COVID-19 Pandemic, Childhood Obesity, Overweight, Childhood
- Trial name
- COLC-Pro (NCT05336591)
- Testing
- Covid-19 pandemic
- Where
- Netherlands
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pneumonia
Efficacy of Single Versus Double Dose of Oral Amoxicillin for Non-Severe Pneumonia in Children
The World Health Organization's (WHO) standard case management strategy for reducing acute respiratory infection (ARI) related mortality recommends oral cotrimoxazole and oral amoxicillin as first line drugs for the treatment of…
- Trial name
- NCT00130013
- Testing
- Oral Amoxicillin
- Where
- Pakistan
- Volunteers
- 900 people
- Sponsor
- ARI Research Cell
Pneumonia, Pneumonia in Children
Assessing Role of Probiotics in Children Aged 6-36 Months Treated for Pneumonia
The main questions this study aims to answer are: Does using probiotic nasal spray (LiveSpo Navax containing Bacillus subtilis and Bacillus clausii, 1x10^9 CFU/mL), with or without oral probiotics (LiveSpo Pregmom containing…
- Trial name
- NCT07399717
- Testing
- Navax, Navax-PregMom
- Where
- Vietnam
- Volunteers
- 330 people
- Sponsor
- Anabio R&D
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Trimetrexate Plus Leucovorin in Children With Pneumocystis Carinii Pneumonia
To evaluate the safety and efficacy of trimetrexate glucuronate with leucovorin protection in pediatric patients with Pneumocystis carinii pneumonia (PCP) who are refractory to or have demonstrated severe or life-threatening…
- Trial name
- NCT00002317
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- United States
- Sponsor
- U.S. Bioscience
COVID-19, Child, Only
Clinical Trial of Jinzhen Oral Liquid in Treating Children With COVID-19 Infection
Jinzhen oral liquid and Jinhuaqinggan Granules were used in the treatment and the control group for 14 days, respectively, to evaluate the effect of Jinzhen oral liquid in treating children with novel coronavirus infection.
- Trial name
- NCT05507489
- Testing
- Jinzhen oral liquid or Jinhuaqinggan granules
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The Affiliated Hospital of Qingdao University
COVID-19
Efficacy, Immunogenicity and Safety of Inactivated Vaccine (Coronavac) Against SARS-COV2 in Children and Adolescents
To evaluate the efficacy and safety of vaccinating children and adolescents, aged 3 to 17 years, with a two-dose schedule of the inactivated vaccine (Coronavac) against SARS-Cov-2.
- Trial name
- Curumim (NCT05225285)
- Testing
- Inactivated Coronavac/Butantan vaccine, BNT162b2 (Pfizer)
- Where
- Brazil
- Volunteers
- 1,120 people, healthy volunteers welcome
- Sponsor
- Federal University of Espirito Santo
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Multisystem Inflammatory Syndrome in Children (MIS-C)
COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C
The primary objectives of this study are: To determine the proportion of children with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) related death, rehospitalization or major complications after infection with…
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Multisystem Inflammatory Syndrome in Children (MIS-C), Coronavirus Disease 2019 (COVID-19)
- Trial name
- PRISM (NCT04588363)
- Testing
- SARS-CoV-2 and/or MIS-C Exposure
- Where
- 20 sites in United States
- Volunteers
- 244 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Malaria, Pneumonia
Study of Post-Training Supports for Health Workers in Benin
The objective of this study was to determine the effectiveness and cost-effectiveness of a package of interventions to support health workers in Benin (in West Africa) who had been trained to use Integrated Management of…
- Conditions
- Malaria, Pneumonia, Diarrhea, Measles
- Trial name
- NCT00510679
- Testing
- Health worker supports (supervision, job aids, incentives)
- Where
- Benin
- Volunteers
- 1,577 people
- Sponsor
- Centers for Disease Control and Prevention
Acute Respiratory Infection
Children's Automated Respiration Monitor (ChARM) for Child Pneumonia Diagnosis by Community Health Workers in Mali
The primary objective of this study is to estimate the impact of a self-monitoring tool (ChARM), used as a teaching/monitoring device, on the CHWs respiratory rate counting accuracy when assessing children under the age of 5…
- Trial name
- NCT03457519
- Testing
- Children's Automated Respiration Monitor (ChARM)
- Where
- 2 sites in Mali
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Diego Bassani
Acetaminophen,Mechanical Ventilation,Critically Ill Children
Clinical Efficacy of Acetaminophen in Mechanical Ventilation in Children With New Coronary Pneumonia
Patients were randomized to receive either paracetamol during mechanical ventilation. When patients were randomized to receive paracetamol (40 mg/kg per day in 4 doses), a placebo infusion of normal saline was administered…
- Trial name
- NCT05691088
- Testing
- Paracetamol injection
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Second Clinical Medical College of Jinan University
SARS CoV 2 Infection, Alveolar; Injury
The Potential Role of sRAGE, KL-6, and SP-D as Prognostic Factors in Children With COVID-19
COVID-19 causes a wide spectrum of clinical illness, from upper respiratory symptoms to severe respiratory failure and death. Several plasma biomarkers -such as IL-6, C-reactive protein (CRP), D-dimer, the…
- Conditions
- SARS CoV 2 Infection, Alveolar; Injury, Children, Pneumonia, Viral
- Trial name
- NCT05619640
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
SARS-CoV-2, COVID-19
Special Investigation for Booster Dose of Comirnaty in Children Ages 6 Months Though 4 Years
The purpose of this post-marketing study is to assess the safety of Comirnaty monovalent XBB.1.5. for booster vaccination children ages 6 months though 4 years under actual use medical practice.
- Trial name
- NCT06130410
- Testing
- COMIRNATY intramuscular injection
- Where
- Japan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Long COVID
Consequences of COVID-19 Infection for Child Health and Wellbeing: Protocol for a Prospective, Observational, Longitudinal Study in Children
Prospective follow-up of children with SARS-CoV-2
- Trial name
- NCT05799508
- Where
- Italy
- Volunteers
- 1,200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Community-acquired Pneumonia, Child, Only
Stopping Pneumonia Antibiotherapy Regimen Early
The hypothesis for this trial is that an antibiotic strategy for the management of non-severe community-acquired alveolar pneumonia in children aged 3 to 59 months, including amoxicillin 80-100 mg/kg/day for at least 3 days in…
- Trial name
- SPARE (NCT06291012)
- Testing
- Quick response: Amoxicillin for 3 days, Delayed response: Amoxicillin for 5 days, Quick response: Amoxicillin for 5 days
- Where
- France
- Volunteers
- 1,100 people
- Sponsor
- University Hospital, Montpellier
Community Acquired Bacterial Pneumonia, Complicated Intra-Abdominal Infection
Study Evaluating Tigecycline Versus Ceftriaxone In Complicated Intra-Abdominal Infections & Community Acquired Pneumonia
The main purpose of this study is to compare the safety of tigecycline versus a ceftriaxone regimen in pediatric subjects (aged 8 to 17 years) with complicated intra-abdominal infections (cIAI) and community acquired pneumonia…
- Trial name
- NCT01602874
- Testing
- Tigecycline, cIAI: Ceftriaxone with metronidazole, plus if applicable aminoglycoside, CAP: Ceftriaxone, plus if applicable oral clarithromycin
- Sponsor
- Pfizer
Foreign Body Ingestion
Foreign Body Ingestion During COVID-19 Lockdown
Ingestion of foreign bodies (FB) is one of the most observed domestic accidents and a frequent reason for consultation in pediatric emergency departments (PED).
- Trial name
- COCE (NCT05261074)
- Testing
- No intervention
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
SARS CoV 2 Infection, COVID-19
Diagnosis of Respiratory Viruses in Children With Rhinoswab Junior
A study to investigate Rhinoswab as an alternative method to combined throat and deep nasal (CTDN) swab for respiratory sample collection in children who present to the Royal Children's Hospital (RCH) for viral testing.
- Trial name
- NCT05043623
- Testing
- Rhinoswab Junior, Combined nose and throat swab, Saliva swab
- Where
- Australia
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19)
Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19)
The objectives of this intermediate-size expanded access protocol are to assess the safety and efficacy of remestemcel-L in participants with MIS-C associated with COVID-19.
- Trial name
- NCT04456439
- Testing
- Remestemcel-L, Hydrocortisone, Diphenhydramine
- Sponsor
- Mesoblast International Sàrl