Clinical trials: Pneumothorax
Pneumothorax, Primary Spontaneous, VATS
Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)
Guidelines lack high quality evidence on optimal postoperative chest tube and pain management after surgery for primary spontaneous pneumothorax (PSP).
- Conditions
- Pneumothorax, Primary Spontaneous, VATS, Pain, Postoperative, Locoregional Anaesthesia
- Trial name
- NCT06053476
- Testing
- Thoracic epidural analgesia, Single-shot paravertebral block, Late chest tube removal
- Where
- Netherlands
- Volunteers
- 366 people
- Sponsor
- Maxima Medical Center
Non-steroidal Anti-inflammatory Drugs, Pleurodesis
Non-steroidal Anti-inflammatory Drugs in Pleurodesis
Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended in a multimodal pain management to reduce pain intensity and to spare opioid use.
- Conditions
- Non-steroidal Anti-inflammatory Drugs, Pleurodesis, Pneumothorax, Pain Management
- Trial name
- KETOTHORAX (NCT06731647)
- Testing
- pleurodesis procedures, KETOPROFEN(RP19583)
- Where
- France
- Volunteers
- 358 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Tissue Plasminogen Activator
Early Intrapleural TPA Instillation Versus Late
Chest tubes are used for air or fluid removal from the pleural space. When a chest tube is placed, it can be hard for the fluid to drain.Tissue plasminogen activator (tPA) and DNase are given through the chest tube to help with…
- Trial name
- ELEVATE (NCT03167281)
- Testing
- early tPA and DNase
- Where
- United States
- Sponsor
- Prisma Health-Midlands
Interprofessional Approach, Ultrasound
Interprofessional Approach to Ultrasound Diagnosis and Intervention in Critical Care Patients With Pneumothorax and/or Hemothorax
Investigate the efficacy of interprofessional team approach to ultrasound guided diagnosis and intervention (pigtail or chest tube insertion) in critical care patients with Pneumothorax and/or hemothorax.
- Conditions
- Interprofessional Approach, Ultrasound, Intervention, Critical Care
- Trial name
- NCT06825299
- Testing
- Chest-Tube Insertion
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Pneumothorax, Hemothorax
Evaluating Improvised Chest Drainage Techniques in Conflict Zones
This study examines the use of improvised chest drainage systems in managing chest trauma at Wad Madani Teaching Hospital, a low-resource and conflict-affected setting.
- Conditions
- Pneumothorax, Hemothorax, Thoracic Trauma, Flail Chest
- Trial name
- NCT06683976
- Where
- Sudan
- Volunteers
- 180 people
- Sponsor
- Sudan Medical Specialization Board
Spontaneous Pneumothorax, Idiopathic Pneumothorax
Thoracoscopy for Idiopathic Pneumothorax in Children
The goal of this retrospective study is to describe the outcomes of spontaneous idiopathic pneumothorax treated by thoracoscopy with pleural abrasion and blebectomy.
- Conditions
- Spontaneous Pneumothorax, Idiopathic Pneumothorax, Bleb Lung, Child, Only
- Trial name
- THOPED (NCT06734442)
- Testing
- Video-Assisted Thoracoscopy with blebectomy and pleural abrasion
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pneumothorax At Trauma Patients
Chest Ultrasound Versus Chest X-ray with Ct As Gold Standard At Trauma Patients
The goal of this observational study is to learn about the predictive value of the chest ultrasound in detection of pneumothorax at chest trauma patients.
- Trial name
- NCT06699277
- Volunteers
- 100 people
- Sponsor
- Assiut University
Trigger Point Pain, Myofascial
Safe Zone in Trigger Point Injection
The goal of this observational study is to define the safe distance that will reduce the risk of pneumothorax through ultrasonographic imaging measurements in both sitting and prone positions to ensure patient safety during these…
- Trial name
- NCT06664359
- Testing
- Ultrasound guided injection with local anaestethic
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people
- Sponsor
- Ankara University
Spontaneous Pneumothorax
Clinical Characteristics and Outcome of Patients Xith Spontaneous Pneumothorax
Pneumothorax occurs when air accumulates between the visceral and parietal pleura, and canbe defined as spontaneous, iatrogenic or traumatic. Spontaneous pneumothorax further classified as primary or secondary.
- Trial name
- NCT06644820
- Testing
- radiology
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pneumothorax Iatrogenic Postprocedural
Characteristics of Pneumothorax Associated With Transthoracic Percutaneous Lung Biopsy in Standard of Care
The number of lung biopsies has increased steadily in recent years. Pneumothorax is the most common complication of a lung biopsy and can occur during the procedure, immediately after the procedure or within a few hours (delayed…
- Trial name
- PNOrate (NCT05259293)
- Testing
- No intervention - retrospective study
- Where
- 6 sites in France, Ireland and 1 more
- Volunteers
- 243 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary
Chest Drain Insertion Assisted by Virtual Reality
Clinical study aiming to investigate the potential benefit of the use of virtual reality helmet as a distractor during chest drain insertion to alleviate patients\' pain and anxiety
- Conditions
- Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary, Pleural Effusion
- Trial name
- CASVIA (NCT06589739)
- Testing
- Virtual Reality Headset
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Pneumothorax
Evaluation of the Feasibility, Safety, and Efficacy of Single-use Endobronchial Silicon Spigots for the Treatment of Refractory Pneumothorax
Study Objective: To evaluate the feasibility and safety of the disposable endobronchial silicon spigots for treating refractory pneumothorax and to preliminarily assess its efficacy, providing domestic experience for the…
- Trial name
- NCT06515015
- Testing
- Endobronchial Silicon Spigots
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Hangzhou Broncus Medical Co., Ltd.
Primary Spontaneous Pneumothorax
Autologous Blood Patch for Primary Spontaneous Pneumothorax
The purpose of this study is to show that treatment with prophylactic autologous blood patch (ABP) after management of primary spontaneous pneumothorax (PSP) is feasible, reduces the incidence of prolonged air leaks, and reduces…
- Trial name
- NCT06088901
- Testing
- Autologous Blood Patch
- Where
- United States
- Sponsor
- Rush University Medical Center
Primary and Secondary Spontaneous Pneumothorax
Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?
Investigators aim to assess if NSAIDs affect the quality of pleurodesis resulting from mechanical pleurodesis (open surgery or VATS) regarding : Primary outcome: Recurrence of pneumothorax in 6 monthes.
- Trial name
- NCT06467318
- Testing
- Paracetamol, NSAID, Paracetamol
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pneumothorax and Air Leak
The Role of Clamping Before Removal of a Pneumothorax Drain Connected to a Digital Drainage System.
The study will be conducted as a, prospective, open label, non-inferiority, randomized controlled trial. In the intervention group; chest tube removal will be determined by air flow criteria as indicated by the digital drainage…
- Trial name
- NCT05180955
- Testing
- Digital drainage system, Digital drainage system + clamping trial
- Where
- Netherlands
- Volunteers
- 92 people
- Sponsor
- Isala
Primary Spontaneous Pneumothorax
Study Compares Pneumothorax Recurrence: Absorbable Mesh vs. Pleurectomy in Primary Spontaneous Pneumothorax.
This is a prospective, randomized controlled trial (pilot study) that aims to determine the incidence of post-operative recurrent pneumothorax within one-year timeframe after video-assisted thoracoscopic blebectomy/bullectomy…
- Trial name
- NCT06413966
- Testing
- Partially absorbable mesh, Apical pleurectomy
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Chiang Mai University
Pneumothorax, Cardiac Surgery
Nurse-performed Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax.
This is a prospective, single-center, observational, cross-sectional cohort study, comparing nurse-performed bedside lung ultrasound to standard portable CXR, for the detection of pneumothorax in the cardiac surgery patient…
- Trial name
- NCT04678726
- Testing
- Lung ultrasound assessment for ruling out pneumothorax
- Sponsor
- University Health Network, Toronto
Pneumothorax
The Diagnostic Value of End-Tidal CO2 in Patients Diagnosed With Pneumothorax
Pneumothorax (PTX) is defined as the accumulation of air in the pleural space. PTX can cause a disruption in the perfusion of lung tissue in the affected area and increase intrathoracic pressure, potentially leading to…
- Trial name
- NCT06276751
- Testing
- End-tidal CO2 monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Ankara City Hospital Bilkent
Pediatric Disorder, Pneumothorax, Spontaneous
Single Site Thoracic Surgery for Pediatric Pneumothorax
Video-Assisted Thoracoscopic Surgery (VATS) has become a standard of care in adults, pediatric surgeons have been slower to undertake this approach. There are limitations for working in children.
- Conditions
- Pediatric Disorder, Pneumothorax, Spontaneous, Thoracic Diseases, Thoracic Surgery
- Trial name
- NCT05034640
- Testing
- Conventional multiport thoracoscopic surgery, Single port site thoracoscopic surgery
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Loma Linda University
Pulmonary Langerhans Cell Histiocytosis
Assessment of Safety of Air Travel in Patients With Pulmonary Langerhans Cell Histiocytosis
The aim of this study is to conduct survey-based assessments for the safety of air travel in patients with pulmonary Langerhans cell histiocytosis (PLCH).
- Trial name
- NCT03052101
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Cincinnati