Clinical trials: Pneumothorax
Traumatic Pneumothorax
Duration of Chest Tube Suction in Traumatic Pneumothorax
The purpose of this pilot study is to determine whether chest tube suction duration, 24 hours vs 48 hours, prior to water seal affects outcome and length of stay after placement for traumatic pneumothorax.
- Trial name
- NCT04986527
- Testing
- Chest tube suction
- Where
- United States
- Sponsor
- University of Rochester
Pneumothorax, Atelectasis
Digital Air Leak Monitoring for Patients Undergoing Lung Resection
Often the decision for chest tube removal or trial of chest tube clamping is based on subjective assessment. This can lead to delay in chest tube removal.
- Trial name
- NCT01810172
- Testing
- Digital pleural drainage system, Dry suction pleura drainage device
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Nova Scotia Health Authority
Respiratory Failure, Pneumothorax
Mechanical Ventilation During Cardiac Surgery
Background There is no unanimous opinion about a lung-protective strategy in cardiac surgery. Small randomized clinical and animals trials suggest that ventilation during cardio-pulmonary bypass (CPB) could be protective on the…
- Conditions
- Respiratory Failure, Pneumothorax, Atelectasis, Aspiration Pneumonia
- Trial name
- NCT02090205
- Testing
- Non-ventilation during CPB, Ventilation with CPAP, Ventilation with 5 act/minute
- Where
- 13 sites in Italy
- Volunteers
- 780 people
- Sponsor
- Ospedale San Raffaele
Pneumothorax
Percussion Device (PD) for Detection of Pneumothorax
This study aims to examine the safety and efficacy of the Percussion Device in detecting a pneumothorax in patients that have undergone thoracic surgery.
- Trial name
- NCT03272815
- Testing
- Percussion Device (PD), Ultrasound (US)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lung Tumor, Pneumothorax
The Depth of Right Bronchial Blocker Placement in Taiwanese in Video-assisted Thoracoscopic Surgery(VATS)
A retrospective study to demonstrate the optimal depth of right side bronchial blocker for complete right lung separation. Data were collected from all patients who completed right side VATS with right side BB from Jan 2010…
- Trial name
- NCT01388803
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax
Primary Versus Delayed Surgical Therapy for Pediatric Spontaneous Pneumothorax
The purpose of this study is to compare the effectiveness of two treatment strategies--delayed versus immediate surgery-- for children with primary spontaneous pneumothorax (collapse of the lung).
- Trial name
- NCT02449980
- Testing
- Primary Surgery Group, Initial Non-operative management
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Baylor College of Medicine
Primary Spontaneous Pneumothorax, Pleural Disease
Study Designed to Optimize the Treatment of Primary Pneumothorax
Knowledge about incidence, risk factors and genetic predispositions of primary spontaneous pneumothorax in young adults is very limited, and treatment has also been controversial.The Aim of this study is to optimize the…
- Trial name
- TOPP (NCT02866305)
- Testing
- VATS bullectomy and mechanical pleuradesis., Chest tube insertion, Epidural
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Odense University Hospital
Pneumothorax, Spontaneous
Spontaneous Pneumothorax in Adolescents
Pneumothorax is characterized by an abnormal presence of air in the pleural cavity, that is to say between the two layers of the pleura, the membrane that surrounds the lungs and lines the rib cage.
- Trial name
- PNSA (NCT06175416)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Strasbourg, France
Pneumothorax, Pulmonary Contusion
Electrical Impedance Imaging of Patients on Mechanical Ventilation
The goal of this study is to evaluate the sensitivity and specificity of Electrical Impedance Tomography (EIT) as a bedside diagnostic tool for lung pathologies in patients who are mechanically ventilated.
- Conditions
- Pneumothorax, Pulmonary Contusion, Pleural Effusion, Pulmonary Edema
- Trial name
- NCT02232841
- Testing
- Mechanical Ventilation, CT Scan
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Colorado State University
Lung Biopsy
Effect of Autologous Blood Patch Injection Versus BioSentry Hydrogel Tract Plug in the Reduction of Pneumothorax Risk Following Lung Biopsy Procedures
The purpose of this study is to compare two methods that are currently used at the end of a CT guided lung biopsy to close the hole on the surface of the lung in order to minimize the chance of air leaking out of the hole.
- Trial name
- NCT02224924
- Testing
- ABPI, BioSentry (formerly known as Bio-Seal) hydrogel Tract Plug
- Where
- 2 sites in United States
- Volunteers
- 454 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Leiomyomatosis
Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)
Pulmonary lymphoangioleiomyomatosis (LAM) is a rare destructive lung disease typically affecting women of childbearing age. Currently, there is no effective therapy for the disease and the prognosis is poor.
- Trial name
- NCT00001869
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pneumothorax, Pleural Effusion
Study of the Benefits of Virtual Reality Headsets for Reducing Anxiety in Patients Treated for Pleural Effusion or Pneumothorax Using Small-bore Chest Drainage Tubes
Pleural effusion and pneumothorax are common conditions encountered in pulmonology departments and may require chest drainage. However, the chest drainage procedure can cause anxiety in patients, leading to discomfort during the…
- Conditions
- Pneumothorax, Pleural Effusion, Drainage of Liquor
- Trial name
- eSEDATION (NCT07206940)
- Testing
- Drainage with Headset Hypno VR
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chest Tube Removal
Clinical Trial Evaluating the Optimal Technique for Chest Tube Removal
There are two commonly used methods to remove chest tubes following thoracotomy. One is to remove the chest tube at maximum inspiration, (patient is asked to take a deep breath in and hold it), and the other is to pull the chest…
- Trial name
- NCT00873587
- Testing
- Chest tube pull on inspiration, Expiration
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pneumothorax At Trauma Patients
Chest Ultrasound Versus Chest X-ray with Ct As Gold Standard At Trauma Patients
The goal of this observational study is to learn about the predictive value of the chest ultrasound in detection of pneumothorax at chest trauma patients.
- Trial name
- NCT06699277
- Volunteers
- 100 people
- Sponsor
- Assiut University
Subclavian Vein Catheterization
Effect of Mechanical Ventilation on the Incidence of Pneumothorax After Subclavian Vein Catheterization
The purpose of this study is to determine whether mechanical ventilation influences the incidence of pneumothorax after subclavian venous catheterization.
- Trial name
- NCT01815801
- Testing
- Lungs were not mechanically ventilated during subclavian vein catheterization, Lungs were mechanically ventilated during subclavian vein catheterization
- Where
- South Korea
- Volunteers
- 334 people
- Sponsor
- Seoul National University Hospital
Pectus Excavatum
Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children
This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE)…
- Trial name
- ECO_NUSS (NCT03073616)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Nicola Disma, MD
Pulmonary Disease, Postoperative Respiratory Complications
Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography
The purpose of this study is to determine whether Electrical Impedance Tomography can be used as sensitive and specific predictor in the detection of postoperative pulmonary complications (e.g.
- Conditions
- Pulmonary Disease, Postoperative Respiratory Complications, Malignant Neoplasm of Stomach, Liver Diseases
- Trial name
- NCT02337673
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Johannes Gutenberg University Mainz
Pneumothorax Spontaneous Primary
Outpatient Management of Primary Spontaneous Pneumothorax: Pigtail Catheter With Unidirectional Valve vs. Exsufflation, Randomized Prospective Study
The management of large spontaneous pneumothorax is not consensual. Current practice involves placement of a Fuhrman catheter connected to a one-way valve, with outpatient monitoring in pneumology consultation.
- Trial name
- PNEUM-AMBU (NCT03691480)
- Testing
- Fuhrman catheter insertion, Three-way stopcock open, Manual aspiration
- Where
- 5 sites in France
- Volunteers
- 148 people
- Sponsor
- Rennes University Hospital
Thoracic Surgical Procedures
Thoracoscopic Bullectomy Versus Thoracoscopic Bullectomy With Pleurodesis in Primary Spontaneous Pneumothorax
The exact pathogenesis of PSP is controversial. A few theories has been proposed contributing to the pathogenesity of the PSP as emphysematous like changes (ELCs) which lead to the formation and rupture of the lung bullae or…
- Trial name
- NCT03943069
- Testing
- Thoracoscopic bullectomy alone, Thoracoscopic bullectomy with pleurodesis
- Where
- Saudi Arabia
- Volunteers
- 232 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Primary Spontaneous Pneumothorax
Effect of Tetracycline Pleurodesis on Prevention of Primary Spontaneous Pneumothorax Recurrence
Primary spontaneous pneumothorax (PSP) defines as presence of air in chest cavity occurs most commonly in young, tall, and smoker men without underlying lung disease. Trends for PSP treatment tend toward more invasive procedures.
- Trial name
- NCT03634605
- Testing
- Chemical pleurodesis, Tetracycline Topical Ointment, Normal saline
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences