Clinical trials: Pocket, Periodontal
Periodontal Pocket, Periodontal Diseases
Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment
The objective of this study will be to evaluate a new protocol for the surgical treatment of periodontal disease with two novelties: to make a single incision in the midline of the interproximal area to respect the vascular…
- Conditions
- Periodontal Pocket, Periodontal Diseases, Periodontal Bone Loss
- Trial name
- NCT05533528
- Testing
- periodontal surgery
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad de Murcia
Periodontal Diseases, Periodontal Pocket
Evaluation of the Rinse With Chlorhexidine Plus Hyaluronic Acid Mouthwash in Periodontal Surgical Wound Healing
Evaluate the response of the gingival tissues to the use of mouthwash with chlorhexidine and chlorhexidine + hyaluronic acid in terms of healing of the periodontal surgical wound.
- Trial name
- CLOR_3 (NCT04345744)
- Testing
- Periodontal surgery, Hyaluronic and 0.2% chlorhexidine mouth rinse, Chlorhexidine 0.2% mouth rinse
- Where
- Italy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Periodontal Pocket
Quantitation of Bacteria Associated With Severe Periodontitis by Real -Time PCR Following Application of Diode Laser
1. Primary objective To measure the gingival crevicular levels of A.actinomycetemcomitans and P.gingivalis after intra-pocket application of diode laser in severe periodontitis (stage 3 grade C) patients. 2.
- Trial name
- NCT05222737
- Testing
- medency diode laser, spirazole forte
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Periodontitis, Surgery
Metronidazole vs Azithromycin in Periodontal Surgery for Patients Positive to Porphyromonas Gingivalis
The objective of this study is to determine whether, in patients with non treated periodontitis (stage III and IV) positive to Porphyromonas gingivalis, the use of systemic antimicrobials (metronidazole versus azithromycin) as an…
- Trial name
- NCT03862456
- Testing
- Azithromycin, Metronidazole
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Periodontal Pocket
Gingival Crevicular Fluid Bone Morphogenetic Protein - 2 Release Profile Following the Use of Perforated Membrane
One of the most important elements suggested to be provided through membrane perforations to augment regeneration are cell released growth factors from the overlying periosteal and gingival cells.
- Trial name
- MPM (NCT01860495)
- Testing
- perforated membrane, G2
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Periodontal Diseases
Efficacy of Subgingival Erythritol Air Polishing in Treatment of Periodontal Pockets
Periodontitis is an inflammation associated with destruction of the periodontium that ultimately, if not treated, leads to tooth loss.
- Trial name
- NCT05798871
- Testing
- Subgingival erythritol air polishing, Conventional root planing
- Where
- Iraq
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontitis, Periodontal Pocket
Comparing Different Timings for Periodontal Re-evaluation After Non-surgical Periodontal Therapy (NSPT)
This is a prospective cohort study that aims to describe the difference in terms of percentage of closed pockets (PPD <5 mm and no BOP) when performing the periodontal re-evaluation at 3-4, 6-8 and 12 months.
- Trial name
- NCT05088746
- Testing
- Non-surgical periodontal therapy
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Parma
Periodontal Pocket
Dietary Intakes and Periodontal Outcomes After Sanative Therapy
Periodontitis is a chronic inflammatory disease and a significant risk factor for tooth loss. While a link between diet and periodontal health exists, the relationship between diet and healing following periodontal therapy has…
- Trial name
- NCT02291835
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Brock University
Periodontal Pocket, Periodontitis
Evaluation Of Nonsurgical Treatment Of Deep Periodontal Pockets (7-10mm) Using AIRFLOW® Prophylaxis Master Device With Erythritol Powder vs Conventional Instrumentation
Periodontitis is a chronic condition associated with the inflammatory destruction of the periodontal tissues ultimately leading to tooth loss.
- Conditions
- Periodontal Pocket, Periodontitis, Gingival Diseases, Gingival Bleeding
- Trial name
- NCT06490679
- Testing
- Hand and ultrasonic scalers and curettes, Electro Medical Systems AIRFLOW® Prophylaxis Master Device
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pocket Depth, Plaque Accumulation
Microbial and Periodontal Changes Associated With Conventional Versus Self Ligating Brackets
Microbial and periodontal changes associated with conventional versus self ligating brackets. The aim of this study will be to compare microbial and periodontal changes associated with conventional versus self ligating brackets.
- Conditions
- Pocket Depth, Plaque Accumulation, Gigival Bleeding
- Trial name
- NCT02436525
- Testing
- conventional stainless steel orthodontic brackets ligated with stainless steel ligature (Oromco - USA), passive self-ligating stainless steel orthodontic brackets (Oromco - USA), active self-ligating stainless steel orthodontic brackets (Oromco - USA)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Periodontitis
Effect of Disinfective Solution as an Adjunct to Maintenance Therapy of Inflamed Periodontal Pockets
This study will determine whether the supplemental use of chemical pocket disinfection with scaling and root planing is more effective than scaling and root planing alone in clinically reducing periodontal probing depth (PD)…
- Trial name
- NCT02316652
- Testing
- Scaling and root planing, Scaling and root planing with solution
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Periodontitis, Periodontal Pocket
Ultrasonic Versus Ultrasonic+ for Effective Sanative Therapy
Periodontitis is a chronic oral infection that results in the breakdown of connective tissue and alveolar bone that support the teeth.
- Trial name
- NCT03074565
- Testing
- Ultrasonic alone, Ultrasonic+
- Where
- 2 sites in Canada
- Volunteers
- 42 people
- Sponsor
- Brock University
Periodontitis
Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis Treatment
Periodontitis is a destructive chronic inflammatory disease characterized by periodontium damage and pocket formation between the tooth and the gingival margin resulting in ultimate tooth loss.
- Trial name
- NCT05583643
- Testing
- Atorvastatin Calcium, Scaling and debridement only
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Periodontitis, Periodontitis (Stage 3)
Periodontal Dressings in Non-Surgical Therapy
This study aims to evaluate and compare the efficacy of two different eugenol-free periodontal dressing materials-Ora-Aid (a hydrophilic polymer) and Coe-Pak (a zinc oxide-based paste)-following non-surgical periodontal treatment…
- Conditions
- Periodontitis, Periodontitis (Stage 3), Periodontal Pocket
- Trial name
- NCT07472218
- Testing
- Ora Aid application, Coe-Pack application
- Volunteers
- 25 people
- Sponsor
- Saglik Bilimleri Universitesi
Periodontal Diseases, Periodontal Attachment Loss
Clinical Effectiveness of Biologic Agents as an Adjunct to Non-surgical Periodontal Therapy of Intrabony Defects
The aim of the present study is to clinically and radiographically compare the efficacy of recombinant human platelet-derived growth factor (rhPDGF), Leukocyte-Platelet Rich Fibrin (L-PRF) and Enamel Matrix Derivatives (EMD) in…
- Conditions
- Periodontal Diseases, Periodontal Attachment Loss, Pocket, Periodontal, Intrabony Periodontal Defect
- Trial name
- NCT05858411
- Testing
- SRP+rhPDGF, SRP+L-PRF, MINST alone
- Where
- Albania
- Volunteers
- 88 people
- Sponsor
- G. d'Annunzio University
Periodontal Pocket, Xerostomia
Periodontal Outcomes After Sanative Therapy
Salivary gland hypofunction, or dry mouth, is a damaging oral condition that affects salivary gland production. Absence of saliva causes bad breath, dental decay, increased plaque accumulation, dry lips, mouth sores, and the…
- Conditions
- Periodontal Pocket, Xerostomia, Dry Mouth, Periodontal Diseases
- Trial name
- NCT03649789
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Brock University
Periodontitis
Intra-pocket Application of Tea Tree Oil Gel in the Treatment of Stage-2 Periodontitis
This study aimed to assess clinically and biochemically the effect of intrapocket application of tea tree oil (TTO) gel adjunctive to SRP in the management of stage 2(moderate) periodontitis and to correlate the biochemical…
- Trial name
- NCT04769271
- Testing
- Scaling and Root Planing, Scaling and Root Planing with tea tree oil
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Periodontitis, Periodontal Diseases
Inulin Supplementation During Sanative Therapy to Further Improve Periodontal Healing
The aim of this study is to investigate the effectiveness of daily supplementation with inulin before, during and after sanative therapy (ST), on clinical outcomes of periodontal disease.
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket
- Trial name
- NCT04670133
- Testing
- Inulin, Maltodextrin
- Sponsor
- Brock University
Periodontal Pocket
The Proposed Study Aims to Investigate the Impact of Adjunctive Vitamin D Gel Application on Gingival Crevicular Fluid Levels of Alkaline Phosphatase and Interleukin-8 in Periodontitis Patients Undergoing Phase 1 Periodontal Therapy. By Elucidating the Molecular Mechanisms Underlying the Therapeutic
The proposed study aims to investigate the impact of adjunctive vitamin D gel application on gingival crevicular fluid levels of alkaline phosphatase and interleukin-8 in periodontitis patients undergoing phase 1 periodontal…
- Trial name
- NCT06669026
- Testing
- vitamin D loaded Poly lactic-co-glycolic acid nanoparticles gel, vitamin D3 gel (regular non-nanoparticle form), only mechanical debridement
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periodontitis, Periodontal Pocket
Injectable PRF in Non-Surgical Periodontal Treatment
This study aims to evaluate the clinical and microbiological effects of using injectable Platelet-Rich Fibrin (i-PRF) as an adjunct to non-surgical periodontal therapy (scaling and root planing) in patients with periodontitis.
- Conditions
- Periodontitis, Periodontal Pocket, Alveolar Bone Loss
- Trial name
- IPRF-PERIO (NCT07375004)
- Testing
- Injectable Platelet-Rich Fibrin (i-PRF)., Scaling and Root Planing (SRP).
- Where
- Iraq
- Volunteers
- 18 people
- Sponsor
- Al-Mustansiriyah University