Clinical trials: Point of Care Testing
Gonorrhea Infection
A Study to Evaluate the Performance, Usability, and Contrived Result Interpretation of iStatis Gonorrhea Antigen Test
The objective of this study is to evaluate the performance, usability, and contrived result interpretation of iStatis Gonorrhea Antigen Test (iStatis Gonorrhea Test) in the intended near-patient or point-of-care setting by…
- Trial name
- NCT07569900
- Testing
- iStatis Gonorrhea Antigen Test
- Where
- 3 sites in South Africa
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- bioLytical Laboratories
HIV Infection, HCV Coinfection
Testing and Linkage to Care for Injecting Drug Users in Kenya
Testing and Linkage to Care for Injecting Drug Users in Kenya: Interventions for people who inject drugs (PWID) in sub-Saharan African have been almost entirely absent, despite the fact that in countries like Kenya they…
- Trial name
- NCT01557998
- Testing
- POC CD4 and Peer Case Management, HCV+PWID, Control - No intervention
- Where
- Kenya
- Volunteers
- 9,449 people, healthy volunteers welcome
- Sponsor
- Yale University
Viral Conjunctivitis
ADenoVirus Initiative Study in Epidemiology in UK
The objectives of this study is to assess the characteristics and frequency of adenovirus conjunctivitis in a population of male and female patients from one year of age who present signs and symptoms of acute conjunctivitis.
- Trial name
- NCT02112773
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- NicOx
Liver Cirrhosis
Comparison of Three Transfusion Strategies for Central Venous Catheterization in Cirrhotics: A Randomized Clinical Trial
The aim of this study is to compare three different blood transfusion strategies for coagulopathy correction before central venous catheterization in patients with chronic liver failure (cirrhosis and/or chronic liver graft…
- Trial name
- POCKET (NCT02311985)
- Testing
- Coagulogram-based protocol, Thromboelastometry-based protocol, Restrictive strategy
- Where
- Brazil
- Volunteers
- 57 people
- Sponsor
- Hospital Israelita Albert Einstein
HIV 1 Infection, HIV 2 Infection
A Study to Evaluate Performance, Usability, and Contrived Result Interpretation of TruPlex HIV/HepB/Syphilis Rapid Test
The objectives of this study are as follows: To evaluate the clinical performance of the TruPlex test using capillary blood, EDTA whole blood, EDTA plasma, and SST serum samples collected by trained operators in point-of-care…
- Conditions
- HIV 1 Infection, HIV 2 Infection, Syphilis Infection, Hepatitis B Infection
- Trial name
- NCT07563309
- Testing
- TruPlex HIV/HepB/Syphilis Rapid Test
- Where
- 3 sites in South Africa
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- bioLytical Laboratories
Hematemesis, Melena
Point of Care Testing of Platelet Function in Patients With Acute Upper Gastrointestinal Bleeding
Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency. In an ageing population, antiplatelet drugs are increasingly being prescribed for treatment and prophylaxis against cardiovascular thrombo-embolic…
- Conditions
- Hematemesis, Melena, Gastrointestinal Hemorrhage, Platelet Dysfunction
- Trial name
- POCGIB (NCT03028064)
- Testing
- blood taking
- Where
- China
- Volunteers
- 476 people
- Sponsor
- Chinese University of Hong Kong
Malaria
Innovation Platform
In this study, a prospective evaluation of novel malaria diagnostic tools under development will be performed in malaria-endemic countries to assess their clinical performance for detection of malaria at point-of-care (POC).
- Trial name
- NCT04558528
- Testing
- Novel in vitro diagnostics and medical applications
- Where
- 2 sites in Indonesia, Rwanda
- Volunteers
- 640 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
HIV Infections
Impact of Point-of-care (POC) Viral Load (VL) Testing During Pregnancy in Zimbabwe
The Ministry of Health and Child Care (MOHCC) in collaboration with Clinton Health Access Initiative (CHAI) will conduct an observational cohort study to determine the impact and cost-effectiveness of POC VL testing for pregnant…
- Trial name
- NCT04048629
- Testing
- Point-of-care (POC) viral load (VL) testing plus refresher training, Standard of care central laboratory VL testing plus refresher training
- Where
- 20 sites in Zimbabwe
- Volunteers
- 1,715 people
- Sponsor
- Clinton Health Access Initiative Inc.
Hepatitis B
Evaluation of Hepatitis B Virus (HBV) DNA Test As Point of Care Tool
This is a cross sectional observational study to asses the performance of two novel HBV DNA testing methodologies; a) dried blood spot sampling and b) fingerstick capillary blood using the Xpert® Hepatitis B Virus viral load…
- Trial name
- HBVPOCT (NCT05144776)
- Testing
- GeneXpert HBV DNA Viral Load Assay, Dried Blood Spot HBV DNA test
- Where
- 6 sites in Australia
- Volunteers
- 268 people
- Sponsor
- Kirby Institute
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Men Who Have Sex With Men and Transgender Women
Study to Evaluate the Feasibility of Integrating the Point-of-care Testing for Sexually Transmitted Infections and HIV Into Community-based Clinics for MSM and TGW in Thailand
This will be a prospective study that will enroll up to 2000 MSM and TG from community-based clinics in Bangkok, Chonburi, Chiang Mai, and Songkhla.
- Trial name
- NCT03580512
- Where
- 6 sites in Thailand
- Volunteers
- 2,000 people
- Sponsor
- Thai Red Cross AIDS Research Centre
Breast Cancer
A Prospective Validation Study of a Rapid Point-of-Care Breath Test for Breast Cancer
This is a multicenter, blinded prospective study of 2,000 women undergoing mammography for breast -related symptoms or signs. Breath tests will be performed in order to demonstrate that the outcome of mammography results combined…
- Trial name
- NCT02888366
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Menssana Research, Inc.
Palliative Care
Feasibility Testing of the Quality-monitoring Tool, Qdact, for the Palliative Care Research Cooperative
Few formal mechanisms for collecting, analyzing, and reporting data on quality in palliative care exist. Such infrastructure is needed to understand current clinical practices, inform quality improvement projects, and research…
- Trial name
- QFT (NCT02411305)
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Peritonitis
Point-of-care Test for Diagnosis of Peritonitis in Peritoneal Dialysis Patients
Peritoneal dialysis (PD) is a home-based dialysis therapy and peritonitis is a serious complication in PD. A reliable point-of-care test to detect peritonitis is important for patients to self-detect peritonitis at home as…
- Trial name
- Periplex (NCT04070196)
- Testing
- Periplex
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore General Hospital
CoaguChek® XS System, Coagulation Function
Diagnostic Accuracy Study of a Point-of-Care Test for Coagulation Function
Intraoperative coagulopathies in complex procedures are common. For the diagnosis and adequate therapy, laboratory tests are necessary, which can delay the patient's therapy.
- Trial name
- NCT06037720
- Testing
- Coaguchek testing
- Volunteers
- 50 people
- Sponsor
- Hospital de Base
Critical Care, Child
A Comparison of Laboratory Versus Point of Care (Bedside) APTT Testing
The overall aim of the study is to determine whether point-of-care (bedside) Activated Partial Thromboplastin Time (APTT) testing would be better than laboratory APTT testing in the PICU population (restricted to children under…
- Trial name
- NCT04744701
- Testing
- Hemochron Signature Elite Whole Blood Microcoagulation System
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Leeds
Ovarian Cancer, Endometrial Cancer
Predictors of Ovarian Cancer and Endometrial Cancer for Artificial-Intelligence-Based Screening Tools
The goal of this observational study is to explore the possible associated factors of ovarian cancer and endometrial cancer in Indonesia and develop screening tools that could predict the risk of both types of cancer The specific…
- Conditions
- Ovarian Cancer, Endometrial Cancer, Endometrial Hyperplasia
- Trial name
- NCT05697601
- Testing
- Artificial-Intelligence Based Screening Tools, Pathology analysis
- Where
- Indonesia
- Volunteers
- 2,905 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Liver Transplant; Complications
Lung Ultrasound as a Point of Care Test for Living Donor Liver Transplant Recipients.
Liver transplant is now a standard treatment for end-stage liver disease patients. Pulmonary complications are common in the perioperative period and are associated with adverse outcomes.
- Trial name
- NCT04413695
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Blood Loss Massive, Post Operative Hemorrhage
Evaluation of the Quantra QStat System in Obstetric Patients
This pilot study will assess the performance of the Quantra System with the QStat Cartridge versus standard of care coagulation testing in bleeding pregnant women at delivery.
- Trial name
- NCT05875987
- Testing
- Quantra System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- HemoSonics LLC
Outbreaks
Respiratory Outbreak Mitigation in Long-Term Care Using Point-of-Care Testing
Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with…
- Trial name
- PROMPT-LTC (NCT06660433)
- Testing
- Point-of-care respiratory test platform, Existing respiratory virus testing platform
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Michael Garron Hospital