Clinical trials: Point of Care Testing
Atopic Asthma
Determination of Accuracy in Measurement of Total Immunoglobulin E Using a Test Device in Atopic Subjects
The purpose of this study is to determine the accuracy of the Novel point of care test (POCT) total IgE assay in atopic patients. 120 patients with atopic conditions and approximately 40 healthy subjects will be enrolled.
- Trial name
- NCT02758548
- Testing
- Blood sample, POCT device
- Where
- 12 sites in Germany, Italy and 3 more
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Prosthetic Joint Infection
Diagnostic Utility of a Novel Point-of-Care Test of Calprotectin for Revision Total Knee Arthroplasty
The purpose of this study is to investigate whether there are quantifiable differences in the level of calprotectin in the synovial fluid that allow separation of different modes of joint implant failure (e.g.
- Trial name
- NCT03694925
- Testing
- Calprotectin test
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- The Cleveland Clinic
Post Partum Hemorrhage, Anemia of Pregnancy
Hemoglobin Testing in Pregnant Patients
The project is a prospective observational study aimed to assess and to validate the use of point-of-care hemoglobin testing in pregnancy.
- Trial name
- AnemiaPOC (NCT05977686)
- Testing
- Masimo Root Radical 7 Pulse CO-Oximeter, HemoCue Hb 801
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Acute Coronary Syndrome
Improving the Management of Acute Coronary Syndromes in the Emergency Department
By using a Rapid Cardiac Evaluation (RACE) pathway in the Emergency Department (ED), the investigators can effectively reduce ED wait times and ED length of stay by decreasing overall hospital admissions and telemetry admissions.
- Trial name
- RACE (NCT01563250)
- Testing
- Point of Care testing
- Where
- United States
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Integrated Medical Research LLC
Hypothyroidism
Study to Verify Clinical Utility of Point-of-Care (POC) Thyroid Stimulating Hormone (TSH) Test Kits as Compared to Third Generation TSH Test Kit
This is a Phase 4, single-center, open-label, interventional study, wherein all enrolled subjects will be tested for Thyroid Stimulating Hormone (TSH) by using the quantitative and the qualitative Point-of-Care (POC) TSH test…
- Trial name
- NCT01921452
- Testing
- Quantitative POC TSH Kit, Qualitative POC TSH Kit, Third generation TSH Kit
- Where
- China
- Volunteers
- 283 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Pregnancy Anemia
Non-invasive Point-Of-Care Hemoglobin Testing In An Obstetric Population
Anemia is common during pregnancy due to increased metabolic rate and normal physiologic changes associated with pregnancy. Anemia during pregnancy has been associated with increased of adverse outcomes during delivery and the…
- Trial name
- NCT06521840
- Testing
- Masimo RAD 67
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Beth Israel Deaconess Medical Center
Embolism and Thrombosis, Infection
Evaluation of the LumiraDx Point of Care D-Dimer and CRP Tests
A Multicenter Study Conducted to Evaluate the Agreement between Fingerstick Whole Blood, Venous Whole Blood and Plasma Determined on the LumiraDx Point of Care D-Dimer and Point of Care CRP Tests to Results on the Reference…
- Conditions
- Embolism and Thrombosis, Infection, Inflammation
- Trial name
- NOVEL-3 (NCT04375982)
- Testing
- Venepuncture, Fingerstick
- Where
- 4 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- LumiraDx UK Limited
Upper Respiratory Infection
Point of Care Respiratory Pathogen Testing for Antibiotic Stewardship in Primary Care
The goal of this study is to understand the use of point of care (POC) testing devices in primary care offices to help clinicians diagnose and appropriately treat patients who have symptoms of upper respiratory infections (URIs).
- Trial name
- PROTECT (NCT06765135)
- Testing
- Clinician Survey, Focus Group, Biofire Spotfire Respiratory (R) panel
- Where
- United States
- Volunteers
- 8,000 people
- Sponsor
- University of Pennsylvania
Diabetes
Point-of-Care Testing in Outpatient Diabetes Care
Using a point-of-care (POC) platform, the investigators will investigate the effects of POC testing for glycated hemoglobin (HbA1c) and cystatin C at out-patient clinics on long-term diabetes outcomes.
- Trial name
- NCT06684990
- Testing
- POC testing
- Where
- Taiwan
- Volunteers
- 222 people
- Sponsor
- Taichung Veterans General Hospital
Covid19
Healthy Volunteer COVID-19 Antibody Testing Study
The need for large-scale testing for COVID-19 has been highlighted by both the World Health Organization (WHO) and the UK government.
- Trial name
- NCT04529460
- Testing
- COVID-19 antibody point of care test kit
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Acute Respiratory Tract Infections
FebriDx DISRUPT Acute Respiratory Infection Trial in Acute Respiratory Infection: An Evaluation of FebriDx® POC Test
The aim of this study is to determine performance characteristics of the FebriDx test in predicting viral or bacterial infection etiology among febrile (observed or reported) patients presenting the emergency department, urgent…
- Trial name
- NCT02018198
- Testing
- FebriDx
- Where
- 20 sites in United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Rapid Pathogen Screening
Cardiac Arrest (CA), Pediatric Cardiac Arrest (Simulated)
Augmented Reality-Cardiopulmonary Resuscitation Support for Pediatric Resuscitation
This study evaluates whether an augmented reality cardiopulmonary resuscitation feedback system (AR-CPR) can support health care providers in delivering high-quality chest compressions during pediatric cardiac arrest.
- Conditions
- Cardiac Arrest (CA), Pediatric Cardiac Arrest (Simulated), Cardiopulmonary Resuscitation (CPR)
- Trial name
- AR-CPR (NCT07778823)
- Testing
- AR-CPR
- Where
- 8 sites in United States, Canada
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Coronavirus Infection, COVID-19
Facilitating AcceLerated Clinical Validation Of Novel Diagnostics for COVID-19 (FALCON-C19)
The United Kingdom and wider world is in the midst of the 2019 novel coronavirus (SARS-CoV-2) pandemic. Accurate diagnosis of infection, identification of immunity and monitoring the clinical progression of infection are of…
- Trial name
- FALCON-C19 (NCT04408170)
- Testing
- Point-of-care test for SARS-CoV-2
- Where
- 15 sites in United Kingdom
- Volunteers
- 8,380 people
- Sponsor
- Manchester University NHS Foundation Trust
Acute Myocardial Infarction
SpinChip Hs-cTnI Sample Type Validation
During a heart attack, the protein troponin I is released from the heart muscle into the bloodstream. Measurements of cardiac troponin in blood are used as an aid in the diagnosis of heart attack.
- Trial name
- HEAT-2 (NCT06453707)
- Testing
- SpinChip hs-cTnI
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- SpinChip Diagnostics ASA
Ventilator Associated Pneumonia
Research Title: Efficacy and Safety of Point- Of-care Procalcitonin Test to Reduce Antibiotic Exposure in VAP
Several studies have shown that PCT guidance can reduce the duration of antibiotic treatment for patients with bacterial infections in the ICU, without compromising the safety outcomes.
- Trial name
- NCT03982667
- Testing
- PCT-guided group
- Where
- 2 sites in Malaysia
- Volunteers
- 100 people
- Sponsor
- Mohd Zulfakar Mazlan, MBBS
Oral Cavity Squamous Cell Carcinoma, Oropharynx Squamous Cell Carcinoma
Saliva-based Detection of CD44
The purpose of this study is to test the ability of OncAlert™ to screen for cancer and the reappearance of cancer. OncAlert™ was developed by Vigilant Biosciences, a collaborator in this research study.
- Conditions
- Oral Cavity Squamous Cell Carcinoma, Oropharynx Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Oropharynx, Squamous Cell Carcinoma of the Head and Neck
- Trial name
- Detect 44 (NCT03148665)
- Testing
- OncAlert
- Where
- 4 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Joseph Califano
Diabetes Mellitus, Type 2, Hypoglycemia
FreeStyle Libre 2 Discharge Trial
The goal of this clinical trial is to learn about the benefits of using aa Continuous Glucose Monitoring (CGM) system in patients with diabetes following discharge from the hospital.
- Trial name
- NCT05822232
- Testing
- FreeStyle Libre 2 CGM, FreeStyle Libre Pro blinded CGM, FreeStyle Precision Neo blood glucose meter
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Palo Alto Medical Foundation
Adult Patients Undergoing Cardiac Surgery, High Bleeding Risks
Transfusion Reduction in High-Bleeding-Risk Cardiac Surgery With Desmopressin
Rationale Bleeding after cardiac surgery is a complication that might result in increased morbidity, mortality, and cost of cardiac surgery by 1.76 (confidence interval (CI), 1.64-1.90) times and a median increase in costs by…
- Conditions
- Adult Patients Undergoing Cardiac Surgery, High Bleeding Risks, Planned Elective Cardiac Surgery Using CPB
- Trial name
- REDES-BLEED (NCT07012837)
- Testing
- Desmopresin
- Where
- Saudi Arabia
- Volunteers
- 112 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Healthy and Acutely Ill Children & Adults
Technical Accuracy and Userfriendliness of Two Point-of-care C Reactive Protein Devices in Comparison With Laboratory CRP Testing.
Study to test technical accuracy and userfriendliness of two Point-of-care C Reactive Protein devices (POC CRP devices) in comparison with laboratory CRP testing on children and adults. Research questions: 1.
- Trial name
- NCT01667172
- Testing
- Point-of-Care C Reactive Protein measurement on capillary blood
- Where
- 3 sites in Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Point-of-Care Testing, HIV
Ayaangwaamiziwin Initiative: Carefulness and Preparedness
The goal of this clinical trial is to implement a test, treat, and connect intervention approach using HIV and syphilis rapid point-of-care (POC) testing in 3 Canadian Prairie provinces (Alberta, Manitoba, and Saskatchewan)…
- Conditions
- Point-of-Care Testing, HIV, Syphilis
- Trial name
- AI (NCT06893159)
- Testing
- INSTI HIV-1/2 Antibody Test, INSTI Multiplex HIV-1/2 Syphilis Antibody Test, Multiplo Complete Syphilis (TP/nTP) Antibody Test
- Where
- 8 sites in Canada
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto